Abstract:
:In rats anesthetized with sodium pentobarbital, adrenal venous blood samples were collected and analyzed for epinephrine and norepinephrine by the fluorometric method. Stimulation of the inferior fovea or adjacent areas resulted in a significant increase in epinephrine secretion. Stimulation of some other areas of the floor of the fourth ventricle was associated with a significant decrease in norepinephrine secretion with or without significant decrease in epinephrine secretion. In no instance was observed a significant increase in norepinephrine secretion in response to the medulla oblongata stimulation.
journal_name
Neuroendocrinologyjournal_title
Neuroendocrinologyauthors
Matsui Hdoi
10.1159/000122949subject
Has Abstractpub_date
1979-01-01 00:00:00pages
385-90issue
6eissn
0028-3835issn
1423-0194journal_volume
29pub_type
杂志文章abstract::Phase relation between plasma corticosterone and locomotor activity rhythms was analyzed in individual rats with selective lesions of suprachiasmatic nuclei (SCN). SCN in Wistar male rats were selectively coagulated electrically and the extent of SCN destruction was examined histologically. Spontaneous locomotor activ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123200
更新日期:1981-07-01 00:00:00
abstract::These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123141
更新日期:1981-02-01 00:00:00
abstract::The effects of linear (L) or cyclic (C) somatostatin (SRIF) on the release of growth hormone (GH) as measured both by bioassay and by radioimmunoassay (RIA) were studied in a series of incubation experiments with rat adenohypophyses. Although both forms of SRIF inhibited release of RIA-GH in all experiments, only C-SR...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123204
更新日期:1981-08-01 00:00:00
abstract::Interactions between the hypothalamic-pituitary-adrenocortical (HPA) system and melatonin secretion have been demonstrated, but only the effects of melatonin on the activity of the HPA system have been studied in man. Alterations of melatonin secretion described as low-melatonin syndrome have been demonstrated in pati...
journal_title:Neuroendocrinology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000127186
更新日期:1997-04-01 00:00:00
abstract::Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126940
更新日期:1996-01-01 00:00:00
abstract::Follicle-stimulating hormone (FSH) is involved in the regulation and maintenance of gametogenesis. It exists in multiple molecular forms with different oligosaccharide structures which in turn are influenced by the hormonal milieu. Previous studies from our laboratory demonstrated that antiandrogen administration to i...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000054484
更新日期:1999-10-01 00:00:00
abstract::Measurements of electrical activity and intracellular Ca(2+) levels were performed in perforated-patch clamped GH(3) cells to determine the contribution of large-conductance calcium-activated K(+) (BK) channels to action potential repolarization and size of the associated Ca(2+) oscillations. By examining the dependen...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000069509
更新日期:2003-03-01 00:00:00
abstract::The primary treatment of gastroenteropancreatic neuroendocrine tumors (GEPNETs) is surgery with curative intent or debulking of the tumor mass. In case of metastatic disease, cytoreductive options are limited. A relatively new therapeutic modality, peptide receptor radionuclide therapy (PRRT) with radiolabeled somatos...
journal_title:Neuroendocrinology
pub_type: 杂志文章,评审
doi:10.1159/000335018
更新日期:2013-01-01 00:00:00
abstract::This study was carried out to clarify the central effects of neuropeptide Y (NPY) on gonadotropin and prolactin (PRL) release in the male rat and to evaluate the hypothesis that it may play a role in negative feedback regulation of gonadotropin secretion in the male. NPY (4 micrograms in 2 microliters 0.9% NaCl) or an...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126481
更新日期:1993-06-01 00:00:00
abstract::Light deprivation by blinding or exposure to short photoperiod results in depressed prolactin (PRL) cell activity and gonadal regression in the male Syrian hamster after at least 42-56 days of treatment, and both of these events can be prevented if pineal removal accompanies light deprivation. In the present study, we...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125272
更新日期:1989-11-01 00:00:00
abstract::Neuroanatomical attempts have been made to determine the synapses between luteinizing hormone-releasing hormone (LHRH)-containing neurons and substance P (SP)-containing neurons in the hypothalamus of female rats. Wheat germ agglutinin was injected into the septo-preoptic area (SPA) and found to be incorporated into c...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125724
更新日期:1991-03-01 00:00:00
abstract::Pituitary transcription factor-1 (Pit-1 or GHF-1) is a transcription factor specific to the anterior pituitary and is involved in the expression and regulation of the growth hormone (GH), prolactin (PRL) and thyroid-stimulating hormone (TSH) beta-subunit genes. The expression of these three genes can be modulated by c...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126930
更新日期:1996-01-01 00:00:00
abstract::The ability of the flutamide metabolite Sch 16423 to block androgen receptor binding and inhibit masculine copulatory behavior in male rats was examined. Restoration of copulatory behavior was prevented in Sch 16423-treated rats given two 10-mm testosterone (T)-filled Silastic capsules plus 15 mg Sch 16423 daily for 1...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124510
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) express insulin-like growth factor (IGF)-related factors [IGF1, IGF2; insulin receptor (IR)-A, IR-B; IGF-binding protein (IGFBP) 1-3] as well as somatostatin (SSTRs) and dopamine D2 receptors (D2Rs). OBJECTIVES:To (1) compare mRNA expression of IGF-rel...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000444280
更新日期:2016-01-01 00:00:00
abstract::An experiment was performed on 21-day-old male rats to determine the combined effects of pinealectomy, constant light and darkness, and intraperitoneal (i.p.) thyrotropin-releasing hormone (TRH) on pituitary and plasma radioimmunoassayable thyrotropin (TSH), serum thyroxine (T4), and pituitary, thyroid and body weight...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122751
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND/AIMS:Abuse of toluene products (e.g., glue-sniffing) primarily occurs during adolescence and has been associated with appetite suppression and weight impairments. However, the metabolic phenotype arising from adolescent inhalant abuse has never been fully characterised, and its persistence during abstinence ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000493686
更新日期:2018-01-01 00:00:00
abstract::The neuropeptide galanin (GAL) is widely distributed in the central and peripheral nervous systems where it often coexists with catecholamines and acetylcholine. Recently we have reported that human GAL (hGAL) in man depresses the release of norepinephrine (NE) and the responses to both assumption of upright posture a...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000127143
更新日期:1996-11-01 00:00:00
abstract::We have investigated the hypothesis that administration of progesterone to estrogen-treated ovariectomized (OVX) rats enhances the stimulatory effects of neuropeptide Y (NPY) on the secretion of luteinizing hormone-releasing hormone (LHRH) from median eminence (ME) fragments in vitro. Adult rats were bilaterally OVX a...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125651
更新日期:1990-12-01 00:00:00
abstract::Unlike rats, but similar to primates, guinea pigs exhibit prolonged function of the corpus luteum and elevated progesterone secretion after ovulation. The gonadotropins, estrogen (E) and progesterone (P) have been examined throughout the guinea pig estrous cycle. However, neither prolactin secretion nor its regulation...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126897
更新日期:1995-06-01 00:00:00
abstract::Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000509865
更新日期:2020-07-02 00:00:00
abstract::Prolactin (PRL) secretion from the anterior pituitary is tonically controlled by the activity of the hypothalamic tuberoinfundibular dopaminergic (TIDA) system. Changes in TIDA activity have been associated with the decrease in basal PRL levels shown by hamsters exposed to a short-day photoperiod. Potential concurrent...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000127153
更新日期:1996-12-01 00:00:00
abstract::The timing of the episodic secretion of luteinizing hormone (LH) in ovariectomized ewes was investigated with respect to an ultradian rest-activity cycle. Individual sheep were enclosed in a chamber where their physical activity was continuously monitored, and blood samples for LH analysis were collected at 5-min inte...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123187
更新日期:1981-06-01 00:00:00
abstract::Prolactin release from primary cultured pituitary cells was investigated using a dynamic perifusion system. Although epinephrine (1 mumol/l) produced an elevation in the mean value of the prolactin concentration at the onset of the perifusion, the elevation was not statistically significant, and the overall effect of ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126424
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND/AIM:The neuroendocrine tumor (NET) proliferation-based grading system (ENETS/WHO) for gastroenteropancreatic (GEP) tumors has proved reliable for prognostic stratification. To date, concerns exist regarding Ki-67 heterogeneity within the tumor and little is known on whether grade varies between primary and s...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000439434
更新日期:2016-01-01 00:00:00
abstract::The sleep-wakefulness pattern and brain protein levels were determined in rats for 3 h following these conditions: administration of an inhibitor of protein synthesis (anisomycin), administration of several doses of rat growth hormone (GH) or thyrotropin, and administration of a combination of anisomycin + GH or thyro...
journal_title:Neuroendocrinology
pub_type: 杂志文章,评审
doi:10.1159/000122377
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:The reviewing and assessment of epidemiological characteristics of neuroendocrine tumours (NETs) remains a challenge. Despite the fact that it is an uncommon family of neoplasms, several worldwide series have revealed an increasing incidence of this rare condition. However, the data are difficult to compare ...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000441897
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND/AIMS:Cervical stimulation induces a circadian rhythm of prolactin secretion and antiphase dopamine release. The suprachiasmatic nucleus (SCN) controls this rhythm, and we propose that it does so through clock gene expression within the SCN. METHODS:To test this hypothesis, serial blood samples were taken fr...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000254379
更新日期:2010-01-01 00:00:00
abstract::Acetylcholinesterase (AChE) activity, and concentrations of monoamines, monoamine metabolites and oxytocin (OT) were measured in the cerebrospinal fluid (CSF) of sheep during late pregnancy, labour, parturition, vaginocervical stimulation, lamb separation and suckling. Concentrations of AChE, 4-hydroxy-3 methoxyphenyl...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124638
更新日期:1986-01-01 00:00:00
abstract:CONTEXT:Early pubertal luteinizing hormone (LH), and by inference gonadotropin-releasing hormone (GnRH), pulse secretion is marked by high nocturnal but low daytime frequency; however, the underlying mechanisms remain unclear. Plasma concentrations of progesterone, the major regulator of GnRH frequency in women, increa...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000336395
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Activation of somatostatin receptors (sstr1-5) by somatostatin and its analogues exerts an inhibitory effect on hormone secretion and provides the basis for the treatment of a range of endocrine diseases such as acromegaly, Cushing's disease and neuroendocrine tumors (NET). The lack of well-characterized com...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000330616
更新日期:2012-01-01 00:00:00