Phase relation between episodic fluctuations of spontaneous locomotor activity and plasma corticosterone in rats with suprachiasmatic nuclei lesions.

abstract：:Diurnal variations, ranging over a twofold difference in concentrations of dopamine, norepinephrine and epinephrine, occur in the rat posterior pituitary gland during a 24-hour period. Highest catecholamine concentrations were seen during daylight hours and low levels reached a nadir 5 h after the onset of darkness. D...

journal_title：Neuroendocrinology

authors： Barden N,Chevillard C,Saavedra JM

更新日期：1982-02-01 00:00:00

abstract：:alpha-Methyl-p-tyrosine (alpha-MT), a competitive inhibitor of tyrosine hydroxylase, was used to block the synthesis of hypothalamic catecholamines in immature female rats of 14, 16 and 30 days of age and in castrated adults. The administration of alpha-MT (300 mg/kg body weight, free base) induced a significant decay...

journal_title：Neuroendocrinology

authors： Moguilevsky JA,Arias P,Szwarcfarb B,Carbone S,Rondina D

更新日期：1990-10-01 00:00:00

abstract：:Experiments were carried out to increase the endogenous levels of TRH in brain and spinal cord. After 7 days of continuous oral ingestion of TRH analogs (D-pGlu-Leu-ProNH2, pGlu-Leu-Pro, pGlu-Pro-ProNH2, or pGlu-Leu-pyrrolidide), spinal cord and brain levels of TRH were elevated, whereas the content of TRH metabolite,...

journal_title：Neuroendocrinology

authors： Prasad C,Eloby-Childress S,Iriuchijima T,Wilber JF,Szirtes T,Kisfaludy L

更新日期：1989-02-01 00:00:00

abstract：:The purpose of the present study was to evaluate the opioid receptor subtype mediating opioid modulation of growth hormone (GH) secretion during ontogeny. The mu-agonist morphine and the kappa agonist U50,488 caused a stimulation and inhibition of GH secretion, respectively, on postnatal day 10. Studies on postnatal d...

journal_title：Neuroendocrinology

authors： Eason MG,Francis RS,Kuhn CM

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. AIM:To evaluate the clinicopathological features and therapeutic outcomes of CP diagnosed in the elderly. PATIENTS AND METHODS:A retrospective, multicenter, national study of C...

journal_title：Neuroendocrinology

authors： Iglesias P,Nocete I,Moure Rodríguez MD,Venegas-Moreno E,Ares J,Biagetti B,Rodríguez Berrocal V,Guerrero-Pérez F,Vicente A,Villar-Taibo R,Cordido F,Paja M,Glerean M,González Rivera N,Dios Fuentes E,Blanco C,Alvaréz-Escolá

更新日期：2020-10-09 00:00:00

abstract：:The presence of vasopressin (VP) in pars distalis of rats and pigs was investigated. Using radioimmunoassay and bioassay of VP, a substance with immunological and biological properties of this hormone was found. This substance was not detected in the adenohypophysis of rats with diabetes insipidus. A partial purificat...

journal_title：Neuroendocrinology

authors： Chateau M,Marchetti J,Burlet A,Boulange M

更新日期：1979-01-01 00:00:00

abstract：:The mammalian pineal gland appears to be a major endocrine component in the regulation of photoperiodic responses. The circadian pattern of secretion of the pineal hormone, melatonin, is regulated by the nervous system. Changes in photoperiod, acting via the nervous system, alter the temporal pattern of melatonin secr...

journal_title：Neuroendocrinology

authors： Goldman BD,Darrow JM

更新日期：1983-11-01 00:00:00

abstract：:Recent evidence suggests that the free amino-terminal fragment of procalcitonin (N-PCT) plays a role in the central control of feeding behavior and energy homeostasis. However, little is known about the mechanisms through which N-PCT works. Here we report that intracerebroventricular administration of N-PCT to free-fe...

journal_title：Neuroendocrinology

authors： Tavares E,Miñano FJ

更新日期：2008-01-01 00:00:00

abstract：:The effect of pinealectomy or immunization against melatonin (Mel) and N-acetylserotonin (NAS) on plasma prolactin (Prl) levels was studied in rats following pineal stimulation induced by blinding or exposure to short photoperiods (1 h light and 23 h darkness daily). Blinding alone or together with pinealectomy or imm...

journal_title：Neuroendocrinology

authors： Niles LP,Brown GM,Grota LJ

更新日期：1977-01-01 00:00:00

abstract：:Hereditary cases of growth hormone (GH)-secreting tumors have been classified into three clinical entities: the multiple endocrine neoplasia type 1 (MEN1) syndrome, the Carney complex (CNC) and the isolated familial somatotropinomas (IFS). The genomic defects associated with MEN1 are all linked to various mutations of...

journal_title：Neuroendocrinology

authors： Lytras A,Tolis G

更新日期：2006-01-01 00:00:00

abstract：:Chronic administration of the mineralocorticoid deoxycorticosterone acetate (DOCA) induces a steady and robust increase in salt appetite and plasma Na(+) over the course of treatment. Interestingly, salt appetite behavior persists in rats even with elevated plasma Na(+) levels. Since there is evidence that the pathway...

journal_title：Neuroendocrinology

authors： Lucas LR,Pompei P,McEwen BS

更新日期：2000-06-01 00:00:00

abstract：:To determine the possible physiological role of endogenous growth hormone-releasing factor (GRF) in the neuronal content and release of cerebral somatostatin (SS), we studied the effect of endogenous GRF blockade on the immunoreactive SS (IR-SS) content of cells and media in fetal rat cerebral cortical and hypothalami...

journal_title：Neuroendocrinology

authors： de los Frailes MT,Cacicedo L,Fernandez G,Tolón RM,Jesus Lorenzo M,Aguado F,Sánchez Franco F

更新日期：1992-02-01 00:00:00

abstract：:Relief of symptoms can be achieved following surgery for growth hormone (GH)-secreting adenomas, as well as after pharmacological therapy with somatostatin analogs. Recently, long-acting somatostatin analog depot formulations, octreotide LAR and lanreotide SR have become available. Somatostatin analogs control GH/insu...

journal_title：Neuroendocrinology

authors： Tolis G,Angelopoulos NG,Katounda E,Rombopoulos G,Kaltzidou V,Kaltsas D,Protonotariou A,Lytras A

更新日期：2006-01-01 00:00:00

abstract：:Neuronal nitric oxide synthase, e.g. NADPH diaphorase (NADPH-d), catalyzes formation of the free radical, nitric oxide (NO), and occurs within brain structures that have functional significance for energy fuel homeostasis. The following studies examined whether populations of NADPH-d-positive neurons in the hypothalam...

journal_title：Neuroendocrinology

authors： Briski KP,Sylvester PW

更新日期：1999-03-01 00:00:00

abstract：:Cell-intact patch-clamp recording was used to determine the electrophysiological responses of sheep anterior pituitary gonadotropes to stimulation with gonadotropin-releasing hormone (GnRH). Cells were identified prior to recording by reverse haemolytic plaque assay (RHPA), or using morphological criteria in preparati...

journal_title：Neuroendocrinology

authors： Heyward PM,Chen C,Clarke IJ

更新日期：1993-12-01 00:00:00

abstract：:The role of beta-endorphin in the stimulation of growth hormone secretion elicited by administration of clonidine (Clon), an alpha2-adrenergic agonist, was investigated in awake, freely moving male rats. Animals were infused slowly with either 1 ml of normal rabbit serum (NRS), beta-endorphin antiserum (beta-end-AS) o...

journal_title：Neuroendocrinology

authors： Bruhn TO,Tresco PA,Mueller GP,Jackson IM

更新日期：1989-10-01 00:00:00

abstract：:An ultradian rhythm in adrenal secretion of corticosterone has been described in awake rats using intra-adrenal microdialysis. To determine the role of the autonomic innervation of the adrenal on the expression of the corticosterone rhythm, adrenal extracellular fluid was sampled by intra-adrenal microdialysis in inta...

journal_title：Neuroendocrinology

authors： Jasper MS,Engeland WC

更新日期：1994-02-01 00:00:00

abstract：:Dexras1, a newly identified member of the Ras superfamily of proteins, was discovered in AtT-20 corticotrope cells because its expression was induced in response to glucocorticoids (dexamethasone; Dex). As yet, the function of Dexras1 is unknown, but its rapid induction in response to glucocorticoids suggests the poss...

journal_title：Neuroendocrinology

authors： Brogan MD,Behrend EN,Kemppainen RJ

更新日期：2001-10-01 00:00:00

abstract：:Growth hormone-releasing hormone (GHRH) stimulates GH secretion in man and the hormonal response is specific. The attenuation of GH response to bolus GHRH after prior exposure of GHRH of up to 24 h was not demonstrated in normal or GH-deficient subjects after more prolonged exposure. This suggests that the partial los...

journal_title：Neuroendocrinology

authors： Low LC

更新日期：1991-01-01 00:00:00

abstract：:Neuroanatomical attempts have been made to determine the synapses between luteinizing hormone-releasing hormone (LHRH)-containing neurons and substance P (SP)-containing neurons in the hypothalamus of female rats. Wheat germ agglutinin was injected into the septo-preoptic area (SPA) and found to be incorporated into c...

journal_title：Neuroendocrinology

authors： Tsuruo Y,Kawano H,Hisano S,Kagotani Y,Daikoku S,Zhang T,Yanaihara N

更新日期：1991-03-01 00:00:00

abstract：:The regulation of prolactin secretion by tuberoinfundibular dopamine (DA) neurons appears to be altered in the aged rat: the concentration of prolactin in the serum increases and the activity of the tuberoinfundibular DA neurons decreases. In the young female rat a brief period of stress reduces the tuberoinfundibular...

journal_title：Neuroendocrinology

authors： Demarest KT,Moore KE,Riegle GD

更新日期：1987-05-01 00:00:00

abstract：INTRODUCTION:The pituitary gland has a high expression of somatostatin receptors (SSTRs) and is therefore a potential organ at risk for radiation-induced toxicity after 177Lu-DOTATATE treatment. OBJECTIVE:To study changes in pituitary function in patients with neuroendocrine tumors (NETs) treated with dosimetry-based ...

journal_title：Neuroendocrinology

authors： Sundlöv A,Sjögreen-Gleisner K,Tennvall J,Dahl L,Svensson J,Åkesson A,Bernhardt P,Lindgren O

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Little information is available concerning prognostic factors for bronchopulmonary large cell neuroendocrine carcinomas (BP-LCNECs) and even less is known about combined LCNECs (Co-LCNECs). We investigated whether an integrated morphological, immunohistochemical, and molecular approach could be used for thei...

journal_title：Neuroendocrinology

authors： Milione M,Maisonneuve P,Grillo F,Mangogna A,Centonze G,Prinzi N,Pusceddu S,Garzone G,Cattaneo L,Busico A,Bossi P,Spaggiari P,Pellegrinelli A,Del Gobbo A,Ferrero S,Kankava K,Pruneri G,Rolli L,Roca E,Bercich L,Tiron

更新日期：2020-05-04 00:00:00

abstract：:Introduction Dysregulation of the mTORC1-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive PanNENs. Although everolimus significantly increases progression free survival, most patients acquire secondary...

journal_title：Neuroendocrinology

authors： Terracciano F,Capone A,Montori A,Rinzivillo M,Partelli S,Panzuto F,Pilozzi E,Arcidiacono PG,Sette C,Capurso G

更新日期：2020-07-02 00:00:00

abstract：:Electrical stimulation in the subfornical organ (SFO) alters the excitability of antidromically identified paraventricular nucleus neurons. Extracellular recordings demonstrate that the dominant effect of single stimuli delivered to the SFO on neurohypophyseal oxytocin and vasopressin containing neurons is an increase...

journal_title：Neuroendocrinology

authors： Ferguson AV,Day TA,Renaud LP

更新日期：1984-11-01 00:00:00

abstract：:An experiment was performed on 21-day-old male rats to determine the combined effects of pinealectomy, constant light and darkness, and intraperitoneal (i.p.) thyrotropin-releasing hormone (TRH) on pituitary and plasma radioimmunoassayable thyrotropin (TSH), serum thyroxine (T4), and pituitary, thyroid and body weight...

journal_title：Neuroendocrinology

authors： Relkin R

更新日期：1978-01-01 00:00:00

abstract：:G-protein-coupled receptor 135 (GPCR135), a former orphan GPCR also known as SALPR, has recently been shown to be modulated by relaxin-3 (R3). In addition to GPCR135, R3 has been shown to be an agonist for GPCR142 (which is a pseudogene in the rat) and to activate LGR7, which is primarily the receptor for relaxin-1/2....

journal_title：Neuroendocrinology

authors： Sutton SW,Bonaventure P,Kuei C,Roland B,Chen J,Nepomuceno D,Lovenberg TW,Liu C

更新日期：2004-01-01 00:00:00

abstract：:The studies reported in this paper were undertaken to investigate the effect of chronic (10 day) alcohol consumption on female pituitary-gonadal function. The immature female rat model treated with pregnant mare serum gonadotropin (PMSG) was used since it results in a highly reproducible luteinizing hormone (LH) surge...

journal_title：Neuroendocrinology

authors： Sundberg DK,Bo WJ,Reilly J

更新日期：1987-10-01 00:00:00

abstract：:The effects of acute and chronic administration of a combination of lynestrenol-mestrenol, a widely employed contraceptive medication, on the dopaminergic system of the rat forebrain and striatum were investigated to better understand the biochemical basis of the neurological side-effects of steroid contraceptive drug...

journal_title：Neuroendocrinology

authors： Algeri S,Ponzio F,Dolfini E,Jori A

更新日期：1976-01-01 00:00:00

abstract：:Pregnancy and parturition are associated with opioid-mediated elevations in maternal pain thresholds. This analgesia is subserved by a spinal cord dynorphin/kappa-opiate receptor system. During gestation, elevated pain thresholds are paralleled by a significant increase in the content of dynorphin (1-17 and 1-8) in th...

journal_title：Neuroendocrinology

authors： Medina VM,Dawson-Basoa ME,Gintzler AR

更新日期：1993-09-01 00:00:00