Nanoparticles of star-like copolymer mannitol-functionalized poly(lactide)-vitamin E TPGS for delivery of paclitaxel to prostate cancer cells.

abstract：:Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...

journal_title：Journal of biomaterials applications

authors： Chang H,Xiang H,Yao Z,Yang S,Tu M,Zhang X,Yu B

更新日期：2020-07-01 00:00:00

abstract：:The objective of the present study was to incorporate strontium into calcium phosphate cement combined with a lower single-dose local administration of bone morphogenetic protein-2 to enhance its in vivo biodegradation and bone tissue growth. After the creation of a rodent critical-sized femoral metaphyseal bone defec...

journal_title：Journal of biomaterials applications

authors： Tao Z,Zhou W,Jiang Y,Wu X,Xu Z,Yang M,Xie J

更新日期：2018-07-01 00:00:00

abstract：:The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of ...

journal_title：Journal of biomaterials applications

authors： Banerjee R,Nageswari K,Puniyani RR

更新日期：1997-07-01 00:00:00

abstract：:The effect of hybrid material-graphene flakes with Fe3O4 nanospheres (GO-Fe3O4), graphene oxide (GO) and magnetite nanospheres (Fe3O4) in rotating magnetic field on mammalian cells metabolism has been studied. Several reports shown that exposure to magnetic field may have influence on cellular membrane permeability. T...

journal_title：Journal of biomaterials applications

authors： Urbas K,Jedrzejczak-Silicka M,Rakoczy R,Zaborski D,Mijowska E

更新日期：2016-04-01 00:00:00

abstract：:Polylactic acid (PLA)-derived polymers are widely used in many biotechnological fields, thanks to their biocompatibility and resorbability through natural pathways. Moreover, PLA is one of the few polymers in which both the properties and the stereochemical structure can be easily modified, making possible a specific ...

journal_title：Journal of biomaterials applications

authors： Renò F,Rizzi M,Cannas M

更新日期：2012-08-01 00:00:00

abstract：:The different barriers that slow the penetration of active ingredients administered by the ocular route are described, and some novel dosage forms designed for this route are discussed. Both precorneal and corneal factors considerably restrict ocular penetration. The low bioavailability of classical ophthalmic dosage ...

journal_title：Journal of biomaterials applications

authors： Aiache JM,el Meski S,Beyssac E,Serpin G

更新日期：1997-01-01 00:00:00

abstract：:Devices such as contact lenses and collagen shields have been used to improve the antibiotic bioavailability of eye drops formulations in the treatment of ulcerative keratitis. Nevertheless, these devices are not sustained drug delivery systems, and a combination with eye drops is necessary. In animal patients, it req...

journal_title：Journal of biomaterials applications

authors： Daza JHU,Righetto GM,Chaud MV,da Conceição Amaro Martins V,Lopes Baratella da Cunha Camargo I,Maria de Guzzi Plepis A

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:A functionalized graphene oxide-based thermosensitive hydrogel loaded with docetaxel for intratumoral delivery was designed to enhance therapeutic efficacy and alleviate system toxicity. METHODS:First, graphene oxide was functionalized with chitosan to acquire high stability in physiological solutions. And the...

journal_title：Journal of biomaterials applications

authors： Zhu X,Zhang Y,Huang H,Zhang H,Hou L,Zhang Z

更新日期：2016-03-01 00:00:00

abstract：:The surface quality of coronary stents has a significant influence on its biocompatibility. Therefore, surface polishing is of paramount importance in the production and application of stents. In the present study, electropolishing is performed on 316LVM steel slotted tube coronary stents. Additionally, acid pickling,...

journal_title：Journal of biomaterials applications

authors： Raval A,Choubey A,Engineer C,Kothwala D

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...

journal_title：Journal of biomaterials applications

authors： Edwards A,Carson RJ,Bowald S,Quist WC

更新日期：1995-10-01 00:00:00

abstract：:The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...

journal_title：Journal of biomaterials applications

authors： Carballo J,Ferreirós CM,Criado MT

更新日期：1992-10-01 00:00:00

abstract：:The aim of this pilot study was to evaluate the bioactive, surface-coated polycaprolactone-co-lactide scaffolds as bone implants in a tibia critical size defect model. Polycaprolactone-co-lactide scaffolds were coated with collagen type I and chondroitin sulfate and 30 piled up polycaprolactone-co-lactide scaffolds we...

journal_title：Journal of biomaterials applications

authors： Rentsch C,Schneiders W,Hess R,Rentsch B,Bernhardt R,Spekl K,Schneider K,Scharnweber D,Biewener A,Rammelt S

更新日期：2014-01-01 00:00:00

abstract：:The controlled release of insulin from a series of biodegradable hybrid hydrogel network containing dextran derivative of allyl isocyanate (dex-AI) and poly (D,L) lactide diacrylate macromer (PDLLAM) over a wide range of composition ratio was investigated. Laser confocal scanning microscope was used to understand the ...

journal_title：Journal of biomaterials applications

authors： Zhang Y,Chu CC

更新日期：2002-04-01 00:00:00

abstract：:Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA) scaffolds were fabricated via freeze-drying wi...

journal_title：Journal of biomaterials applications

authors： Koç A,Finkenzeller G,Elçin AE,Stark GB,Elçin YM

更新日期：2014-11-01 00:00:00

abstract：:Hemocompatibility is the goal for any biomaterial contained in extracorporeal life supporting medical devices. The hallmarks for hemocompatibility include nonthrombogenicity, platelet preservation, and maintained platelet function. Both in vitro and in vivo assays testing for compatibility of the blood/biomaterial int...

journal_title：Journal of biomaterials applications

authors： Major TC,Handa H,Annich GM,Bartlett RH

更新日期：2014-10-01 00:00:00

abstract：:The objective of the study was to produce three-dimensional and porous nanofiber reinforced hydrogel scaffolds that can mimic the hydrated composite structure of the cartilage extracellular matrix. In this regard, wet-electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanofiber reinforced carboxymethyl ch...

journal_title：Journal of biomaterials applications

authors： Gunes OC,Albayrak AZ,Tasdemir S,Sendemir A

更新日期：2020-10-01 00:00:00

abstract：:The aim of the in vitro study was a comparison of an allogenic (ABSM) and a xenogenic bone substitute material (XBSM) with and without injectable platelet-rich fibrin (ABSM-i-PRF & XBSM-i-PRF) on cell characteristics of human osteoblasts (HOB). Here, ABSM and XBSM (+ i-PRF = test; - i-PRF = control) were incubated wit...

journal_title：Journal of biomaterials applications

authors： Kyyak S,Blatt S,Pabst A,Thiem D,Al-Nawas B,Kämmerer PW

更新日期：2020-07-01 00:00:00

abstract：:Pluronic® F127 is a biocompatible, injectable, and thermoresponsive polymer with promising biomedical applications. In this study, a chemically modified form, i.e., Pluronic ALA-L with tailored degradation rate, was tested as an encapsulation vehicle for osteoblastic cells. UV cross-linking of the modified polymer res...

journal_title：Journal of biomaterials applications

authors： Lippens E,Swennen I,Gironès J,Declercq H,Vertenten G,Vlaminck L,Gasthuys F,Schacht E,Cornelissen R

更新日期：2013-03-01 00:00:00

abstract：:Biodegradable sponges, as a promising hemostatic biomaterial, has been clinically required over the past decades. Current hemostatic sponges are generally prepared by crosslinking and freeze-drying, but the quality control or biocompatibility is often unsatisfactory due to the freezing-caused morphological non-uniform...

journal_title：Journal of biomaterials applications

authors： Jiang X,Wang Y,Fan D,Zhu C,Liu L,Duan Z

更新日期：2017-03-01 00:00:00

abstract：:Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...

journal_title：Journal of biomaterials applications

authors： Gosau M,Bürgers R,Vollkommer T,Holzmann T,Prantl L

更新日期：2013-08-01 00:00:00

abstract：:The quality and quantity of bone are crucial to the success of dental implant treatment. Recently, bone grafting materials have reached some limitations. This study aimed to evaluate the biocompatibility of novel drug delivery material, injectable methacrylated hyaluronic acid hydrogel incorporated with different rati...

journal_title：Journal of biomaterials applications

authors： Areevijit K,Dhanesuan N,Luckanagul JA,Rungsiyanont S

更新日期：2020-11-04 00:00:00

abstract：:Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...

journal_title：Journal of biomaterials applications

authors： Lusvardi G,Malavasi G,Menabue L,Menziani MC,Pedone A,Segre U,Aina V,Perardi A,Morterra C,Boccafoschi F,Gatti S,Bosetti M,Cannas M

更新日期：2008-05-01 00:00:00

abstract：:A biodegradable polylactic acid composite containing tricalcium phosphate microsphere was fabricated. The composite exhibited enhanced biocompatibility and a well-interconnected porous structure that enabled tissue ingrowth after degradation. The tricalcium phosphate microspheres had an average size of 106 ± 43 μm and...

journal_title：Journal of biomaterials applications

authors： Shin DY,Kang MH,Kang IG,Kim HE,Jeong SH

更新日期：2018-05-01 00:00:00

abstract：:The adhesion of platelets, red blood cells, and lymphocytes onto various polymer substrates, hydrophobic to hydrophilic in nature, has been studied. Cell adhesion is found to be higher on hydrophilic substrates. The stability of these adhered cells has also been studied under a flow rate of 20 ml/min. Further the effe...

journal_title：Journal of biomaterials applications

authors： Sharma CP,Hari PR

更新日期：1991-07-01 00:00:00

abstract：:Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series of N-alkyl-substituted linear polyethylenimine (CP) polymers have been synthesized, characterized, and investigated about how degree of substitution (hydrophobi...

journal_title：Journal of biomaterials applications

authors： Bansal R,Kumar P

更新日期：2017-07-01 00:00:00

abstract：:We assess the effects of chemical processing, ethylene oxide sterilization, and threading on bone surface and mechanical properties of bovine undecalcified bone screws. In addition, we evaluate the possibility of manufacturing bone screws with predefined dimensions. Scanning electronic microscopic images show that che...

journal_title：Journal of biomaterials applications

authors： Haje DP,Volpon JB,Moro CA

更新日期：2009-03-01 00:00:00

abstract：:Aluminum-free glass ionomer cements (GICs) are under development for orthopedic applications, but are limited by their insufficient handling properties. Here, the addition of calcium polyphosphate (CPP) was investigated as an additive to an experimental zinc-silicate glass ionomer cement. A 50% maximum increase in wor...

journal_title：Journal of biomaterials applications

authors： Valliant EM,Gagnier D,Dickey BT,Boyd D,Filiaggi MJ

更新日期：2015-07-01 00:00:00

abstract：:In the present study, a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the treatment of infected wound. Hydrogel-grafted fabric was prepared by graft copolymerization of N-isopropylacrylamide and alginate using ceric ammonium nitrate as initiator. Berberine nanosuspension was pr...

journal_title：Journal of biomaterials applications

authors： Xu H,Yuan XD,Shen BD,Han J,Lv QY,Dai L,Lin MG,Yu C,Bai JX,Yuan HL

更新日期：2014-05-01 00:00:00

abstract：:This study aims the in vivo biological characterization of an innovative minocycline delivery system, based on polymethylmethacrylate bone cement. Bone cements containing 1% or 2.5% (w/w) minocycline were formulated and evaluated through solid-state characterization. Biological evaluation was conducted in vivo, within...

journal_title：Journal of biomaterials applications

authors： Silva T,Silva JC,Colaco B,Gama A,Duarte-Araújo M,Fernandes MH,Bettencourt A,Gomes P

更新日期：2018-09-01 00:00:00

abstract：:Gold nanomaterials possess unique physical and chemical properties, which attracted much attention in recent years. As a new type of gold nanomaterials, gold nanostars (GNSTs) have been prepared and characterized in this study. GNSTs under near-infrared (NIR) light irradiation can exert not only cancer photothermal th...

journal_title：Journal of biomaterials applications

authors： Wang L,Meng D,Hao Y,Zhao Y,Li D,Zhang B,Zhang Y,Zhang Z

更新日期：2015-11-01 00:00:00