Apoptosis induced by bacterial pathogens.

abstract：:The failure of drugs for effective treatment against infectious diseases can be attributed to resistant forms of causative agents. The evasive nature of Mycobacterium tuberculosis is partly associated to its physical features, such as having a thick cell wall and incorporation of beneficial mutations leading to drug r...

journal_title：Microbial pathogenesis

authors： Rabha A,Singh A,Grover S,Kumari A,Pandey B,Grover A

更新日期：2019-04-01 00:00:00

abstract：:Type VI secretion systems (T6SSs) have been identified recently in several Gram-negative organisms and have been shown to be associated with virulence in some bacterial pathogens. A T6SS of Yersinia pestis CO92 (locus YPO0499-YPO0516) was deleted followed by investigation of the phenotype of this mutation. We observed...

journal_title：Microbial pathogenesis

authors： Robinson JB,Telepnev MV,Zudina IV,Bouyer D,Montenieri JA,Bearden SW,Gage KL,Agar SL,Foltz SM,Chauhan S,Chopra AK,Motin VL

更新日期：2009-11-01 00:00:00

abstract：:A cytotoxin to Vero cells (Shiga-like toxin), which was neutralized by antibody against purified Shiga toxin produced by Shigella dysenteriae 1, was purified from Escherichia coli O157:H7, isolated from a patient with hemorrhagic colitis. The purification procedure consisted of ammonium sulfate fractionation, DEAE-cel...

journal_title：Microbial pathogenesis

authors： Noda M,Yutsudo T,Nakabayashi N,Hirayama T,Takeda Y

更新日期：1987-05-01 00:00:00

abstract：:The virulence of Staphylococcus aureus opsonized with an antiserum raised against a recombinant fibronectin-binding protein (FnBP) was compared with homologous, non-opsonized bacteria (treated with pre-immune serum) in a mouse mastitis model. Virulence was evaluated comparing the number of bacteria removed from the in...

journal_title：Microbial pathogenesis

authors： Mamo W,Jonsson P,Müller HP

更新日期：1995-07-01 00:00:00

abstract：:Microbial adherence to host cells is an early key step in the establishment of infection. During the course of Legionnaire's disease, Legionella interactions with host cells are best documented for resident macrophages. However, L. pneumophila can also replicate within type I and type II pneumocytes, which cover almos...

journal_title：Microbial pathogenesis

authors： Yaradou DF,Raze D,Ginevra C,Ader F,Doléans-Jordheim A,Vandenesch F,Menozzi FD,Etienne J,Jarraud S

更新日期：2007-11-01 00:00:00

abstract：:Helicobacter pylori is a microorganism that in the last years has been associated with extragastric disorders such as respiratory diseases, however, its impact on lung is partially understood. The aim of this work was to study infection impact of H. pylori on the inflammatory markers expression at the pulmonary level ...

journal_title：Microbial pathogenesis

authors： Arismendi Sosa AC,Salinas Ibáñez AG,Pérez Chaca MV,Penissi AB,Gómez NN,Vega AE

更新日期：2020-02-26 00:00:00

abstract：:Avian sarcoma virus (ASV)-induced tumor cells that are derived from regressing neoplasms contain about 75% less pp60src kinase activity than do progressively-growing tumor cells. Paradoxically, the polyadenylated RNAs extracted from 'regressor' cells found in regressing neoplasms are much more productive than those fr...

journal_title：Microbial pathogenesis

authors： Poulin L,Wainberg MA

更新日期：1987-02-01 00:00:00

abstract：:We report the development of an in vitro assay using HEp-2 cell monolayers in which cell association of five C. jejuni strains and E. coli K12 C600 were tested under different experimental conditions. Both total cell associated colony forming units (CFU) and the CFU protected from gentamicin killing (i.e. internalized...

journal_title：Microbial pathogenesis

authors： de Melo MA,Pechère JC

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:Prompt genotyping of Mycobacterium tuberculosis (M. tuberculosis) is crucial for improving molecular epidemiological investigation of tuberculosis (TB). METHODS:We performed a retrospective study to evaluate the use of 24 loci MIRU-VNTR (mycobacterial interspersed repetitive unit-variable number of tandem-re...

journal_title：Microbial pathogenesis

authors： Sadegh H,Kargarpour Kamakoli M,Farmanfarmaei G,Masoumi M,Abdolrahimi F,Fateh A,Ebrahimzadeh N,Rahimi Jamnani F,Vaziri F,Siadat SD

更新日期：2017-02-01 00:00:00

abstract：:Cervical cancer is a growing and serious problem world-wide in women, but more acute in developing countries especially in Indian subcontinent. The main causative agent for the disease is Human Papilloma Virus (HPV). The history of the cervical cancer goes back to eighteenth century as the HPV infection is reported si...

journal_title：Microbial pathogenesis

authors： Shah UJ,Nasiruddin M,Dar SA,Khan MKA,Akhter MR,Singh N,Rabaan AA,Haque S

更新日期：2020-06-01 00:00:00

abstract：UNLABELLED:The outcome of Helicobacter pylori infection has been related to specific virulence-associated bacterial genotypes. The vacuolating cytotoxin (vacA), cagA gene, oipA and babA2 gene are important virulence factor involving gastric diseases. The objective of this study was to assess the relationship between vi...

journal_title：Microbial pathogenesis

authors： Salimzadeh L,Bagheri N,Zamanzad B,Azadegan-Dehkordi F,Rahimian G,Hashemzadeh-Chaleshtori M,Rafieian-Kopaei M,Sanei MH,Shirzad H

更新日期：2015-03-01 00:00:00

abstract：:Xylella fastidiosa is a xylem-restricted plant pathogen that causes a range of diseases in several and important crops. Through comparative genomic sequence analysis many genes were identified and, among them, several potentially involved in plant-pathogen interaction. The experimental determination of the primary seq...

journal_title：Microbial pathogenesis

authors： Caruso CS,de Fátima Travensolo R,de Campus Bicudo R,de Macedo Lemos EG,Ulian de Araújo AP,Carrilho E

更新日期：2009-09-01 00:00:00

abstract：:A. baumannii has been considered as Priority-I as suggested by the World Health Organization (WHO) and the most critical pathogenic microorganism for causing nosocomial infection in imunno-compromised hospital-acquired patients due to multi-drug resistance (MDR). In the current study, we utilized "Computer-aided ligan...

journal_title：Microbial pathogenesis

authors： Amera GM,Khan RJ,Pathak A,Jha RK,Muthukumaran J,Singh AK

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Cryptosporidiosis represents a major public health problem. This infection, caused by a protozoan parasite of the genus Cryptosporidium, has been reported worldwide as a frequent cause of diarrhoea. In the immunocompetent host, the typical watery diarrhea can be self-limiting. However, it is severe and chron...

journal_title：Microbial pathogenesis

authors： Chelbi H,Essid R,Jelassi R,Bouzekri N,Zidi I,Ben Salah H,Mrad I,Ben Sghaier I,Abdelmalek R,Aissa S,Bouratbine A,Aoun K

更新日期：2018-02-01 00:00:00

abstract：:Staphylococcus aureus is one of the major bacterial mastitis pathogens with significant effects on animal and human health. Some studies showed that S. aureus strains that infect different host species are genetically distinct, although most strains can infect a wide range of host species. However, there are no clearl...

journal_title：Microbial pathogenesis

authors： Vaughn JM,Abdi RD,Gillespie BE,Kerro Dego O

更新日期：2020-07-01 00:00:00

abstract：:Recent research has shown broad antifungal activity of the classic antidepressants selective serotonin reuptake inhibitors (SSRIs). This fact, combined with the increased cross-resistance frequency of the genre Candida regarding the main treatment today, fluconazole, requires the development of novel therapeutic strat...

journal_title：Microbial pathogenesis

authors： Costa Silva RA,da Silva CR,de Andrade Neto JB,da Silva AR,Campos RS,Sampaio LS,do Nascimento FBSA,da Silva Gaspar B,da Cruz Fonseca SG,Josino MAA,Grangeiro TB,Gaspar DM,de Lucena DF,de Moraes MO,Cavalcanti BC,Nobre Júnior H

更新日期：2017-06-01 00:00:00

abstract：:The corticosteroid-treated animal is well established as an experimental model for the study of Pneumocystis carinii pneumonitis (PCP). Latent or acquired infection with P. carinii in the murine lung progresses to fatal pneumonitis when the host is profoundly immunocompromized. In this study the effects of five immuno...

journal_title：Microbial pathogenesis

authors： Oz HS,Hughes WT,Rehg JE,Thomas EK

更新日期：2000-09-01 00:00:00

abstract：:Yersina enterocolitica-like species have not been extensively studied regarding its pathogenic potential. This work aimed to assess the pathogenic potential of some Y. enterocolitica-like strains by evaluating the presence of virulence-related genes by PCR and their ability to adhere to and invade Caco-2 and HEp-2 cel...

journal_title：Microbial pathogenesis

authors： Imori PF,Passaglia J,Souza RA,Rocha LB,Falcão JP

更新日期：2017-03-01 00:00:00

abstract：:Carbohydrate analyses of whole-spore extracts have confirmed the presence of rhamnose in the spore of the fully virulent Ames strain of Bacillus anthracis. A gene cluster containing loci with high homology to the rhamnose biosynthetic genes, rmlACBD, was identified within the B. anthracis chromosome. The first gene of...

journal_title：Microbial pathogenesis

authors： Bozue JA,Parthasarathy N,Phillips LR,Cote CK,Fellows PF,Mendelson I,Shafferman A,Friedlander AM

更新日期：2005-01-01 00:00:00

abstract：:Pyelonephritis induces an inflammatory process in the renal parenchyma, which may occur as a result of excessive reactive nitrogen intermediates (RNI) and reactive oxygen species (ROS) and/or impaired antioxidant capacity. In the present investigation, contribution of free radicals to the development of acute pyelonep...

journal_title：Microbial pathogenesis

authors： Mittal R,Sharma S,Chhibber S,Harjai K

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Pneumococcal infections have caused morbidity and mortality globally. Streptococcus pneumoniae (pneumococci) are commensal bacteria that colonize the nasopharynx, asymptomatically. From there, pneumococci can spread in the lungs causing pneumonia and disseminate in the bloodstream causing bacteremia (sepsi...

journal_title：Microbial pathogenesis

authors： Rahman NA,Sharudin A,Diah S,Muharram SH

更新日期：2017-09-01 00:00:00

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:Streptococcus suis is an important pathogen in swine, and it also represents an emerging zoonotic agent. Zebrafish as a model for the evaluation of virulence of S. suis has been demonstrated before. Here, an Affymetrix Zebrafish GeneChip was used to identify alterations in gene expression of zebrafish injected with S....

journal_title：Microbial pathogenesis

authors： Wu Z,Zhang W,Lu Y,Lu C

更新日期：2010-05-01 00:00:00

abstract：:The present study was aimed to investigate and understand the mechanism of inhibitory effect of phenyl benzoxime on proliferation of SNU-306 cells. Proliferation of SNU-306 cells transfected with wild-type p53-induced phosphatase 1 (Wip1)-siRNA or treated with phenyl benzoxime was examined by 3-(4,5-dimethythiazol-2-y...

journal_title：Microbial pathogenesis

authors： Chen W,Tan Y,Zhang Y

更新日期：2019-01-01 00:00:00

abstract：:The gene gseA, involved in the expression of the genus-specific epitope of chlamydial lipopolysaccharide (LPS), was analyzed by temperature gradient gel electrophoresis (TGGE) to visualize nucleotide sequence variations among the 15 serovars of Chlamydia trachomatis. Sequence analysis showed that the TGGE melting-prof...

journal_title：Microbial pathogenesis

authors： Mamat U,Löbau S,Persson K,Brade H

更新日期：1994-08-01 00:00:00

abstract：:A collection of Haemophilus ducreyi isolates were screened for the ability to bind to fibrinogen, fibronectin, collagen, gelatin and laminin by a particle agglutination test using latex beads coated with the individual proteins. Thirteen of 21 isolates reacted with all five extracellular matrix proteins. Binding of or...

journal_title：Microbial pathogenesis

authors： Abeck D,Johnson AP,Mensing H

更新日期：1992-07-01 00:00:00

abstract：:In this study, monodispersed, highly biocompatible and substantially stable glucose encapsulated CdO nanoparticles (G-CdO NPs) of uniform sizes were synthesized using a sol-gel route. In addition, naked CdO (n-CdO) NPs without any capping or surface functionalization were synthesized using the same method. These NPs w...

journal_title：Microbial pathogenesis

authors： Zahera M,Khan SA,Khan IA,Elgorban AM,Bahkali AH,Alghamdi SM,Khan MS

更新日期：2018-06-01 00:00:00

abstract：:Molecular prevalence of nine putative virulence factors in two more prevalent Brucella species in Iranian patients and livestock was investigated. During five years (2010-2015), 120 human and animal specimens were collected from three geographical areas of Iran. All samples were cultured in blood culture media and sub...

journal_title：Microbial pathogenesis

authors： Hashemifar I,Yadegar A,Jazi FM,Amirmozafari N

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Rickettsia prowazekii is the etiological agent of epidemic typhus and is an obligate intracellular bacterium that grows as a parasite freely within the cytoplasm of a eukaryotic host cell. Previous studies have shown that rOmpA and rOmpB which belong to the family of rickettsial cell surface antigens are inv...

journal_title：Microbial pathogenesis

authors： Vellaiswamy M,Kowalczewska M,Merhej V,Nappez C,Vincentelli R,Renesto P,Raoult D

更新日期：2011-05-01 00:00:00

abstract：:The transferrin-binding proteins TbpA and TbpB from Pasteurella haemolytica biotype A serotype 1 were tested for their ability to confer protection against experimental P. haemolytica infection when administered to calves in vaccine formulations containing one or both antigens. Vaccine groups included TbpB (single imm...

journal_title：Microbial pathogenesis

authors： Potter AA,Schryvers AB,Ogunnariwo JA,Hutchins WA,Lo RY,Watts T

更新日期：1999-10-01 00:00:00