Serotyping of Brunei pneumococcal clinical strains and the investigation of their capability to adhere and invade a brain endothelium model.

abstract：:Phenotypic serum resistance of gonococci in urethral exudates is due to sialylation of lipopolysaccharide (LPS) by host cytidine 5'-monophospho-N-acetyl neuraminic acid (CMP-NANA). A surface structure was visible on gonococci [strain BS4 (agar)] that had been stained with ruthenium red after incubation with CMP-NANA. ...

journal_title：Microbial pathogenesis

authors： Fox AJ,Curry A,Jones DM,Demarco de Hormaeche R,Parsons NJ,Cole JA,Smith H

更新日期：1991-09-01 00:00:00

abstract：:It has been shown that N-linked high mannose type oligosaccharides competitively inhibits attachment to and infectivity of chlamydiae in HeLa cells. To further study whether mannose moieties are involved in the infectivity of chlamydiae, the susceptibility of mannose-receptor negative J774A and positive J774E mouse ma...

journal_title：Microbial pathogenesis

authors： Kuo CC,Puolakkainen M,Lin TM,Witte M,Campbell LA

更新日期：2002-01-01 00:00:00

abstract：:Helicobacter pylori (H. pylori), which is a spiral-shaped Gram-negative microaerobic bacterium, is a causative pathogen. The entry of H. pylori into gastric epithelial cells involves various host signal transduction events, and its virulence factors can also cause a variety of biological responses. In this study, AGS ...

journal_title：Microbial pathogenesis

authors： Matsunaga S,Nishiumi S,Tagawa R,Yoshida M

更新日期：2018-11-01 00:00:00

abstract：:Vibrio parahaemolyticus is a leading cause of seafood-associated bacterial gastroenteritis. The pathogen produces the thermostable direct hemolysin (TDH), which is the sole cause of the Kanagawa phenomenon (KP), a special β-type haemolysis in the Wagatsuma agar. TDH also exerts several other biological activities, the...

journal_title：Microbial pathogenesis

authors： Cai Q,Zhang Y

更新日期：2018-10-01 00:00:00

abstract：:Strains of the Enterobacter cloacae complex are becoming increasingly important human pathogen. The aim of the study was to identify, by sequencing the hsp60 gene, the species of clinical isolates phenotypically identified as E. cloacae and to examine them for virulence-associated properties: the ability of adhesion, ...

journal_title：Microbial pathogenesis

authors： Krzymińska S,Koczura R,Mokracka J,Puton T,Kaznowski A

更新日期：2010-09-01 00:00:00

abstract：:Dendritic cells (DCs) are key linkages between innate immunity and acquired immunity. The antigens that promote the functions of DCs might be the effective candidates of novel vaccine. In this research, the ability of ubiquitin-conjugating enzyme (UCE), a recognized common antigens among chicken Eimeria species, to st...

journal_title：Microbial pathogenesis

authors： Lakho SA,Haseeb M,Huang J,Hasan MW,Naqvi MA,Zhou Z,Song X,Yan R,Xu L,Li X

更新日期：2020-06-01 00:00:00

abstract：:The goal of this study was to demonstrate the participation in cellular damage of a Trichomonas vaginalis proteinase with a molecular mass of 65 kDa (CP65). By two dimensional gelatin-gel electrophoresis of trichomonad proteins we detected four spots with proteolytic activity on the 65 kDa region, but only one, pI 7.2...

journal_title：Microbial pathogenesis

authors： Alvarez-Sánchez ME,Avila-González L,Becerril-García C,Fattel-Facenda LV,Ortega-López J,Arroyo R

更新日期：2000-04-01 00:00:00

abstract：:Invasion plasmid antigen C (IpaC) is secreted by the Shigella flexneri type III secretion system (TTSS) as an essential trigger of epithelial cell invasion. At the molecular level, IpaC possesses a distinct functional organization. The IpaC C-terminal region between amino acids 319 and 345 is predicted to form a coile...

journal_title：Microbial pathogenesis

authors： Terry CM,Picking WL,Birket SE,Flentie K,Hoffman BM,Barker JR,Picking WD

更新日期：2008-10-01 00:00:00

abstract：:In mice, nitric oxide (NO) production by inducible NO synthase (iNOS), is a component of the control of Brucella infection. In humans, the involvement of iNOS in infection is still a matter of debate. Based on in vitro experiments, it was recently postulated that in humans, Brucella infection tends to become chronic b...

journal_title：Microbial pathogenesis

authors： Gross A,Bertholet S,Mauel J,Dornand J

更新日期：2004-02-01 00:00:00

abstract：:We obtained mutants devoid of the O1-antigen, the capsular polysaccharide (K antigen) or both from Klebsiella pneumoniae clinical isolates (urinary infection). These mutants were grown in urine, and their ability to fimbriate and to adhere were studied. Mutants lacking the O1-antigen, independently of the other surfac...

journal_title：Microbial pathogenesis

authors： Merino S,Rubires X,Aguilar A,Tomás JM

更新日期：1997-07-01 00:00:00

abstract：:Thymol and carvacrol from the class of monoterpene phenols are one of the most potent plant essential oil components possessing antimicrobial effects. Known for their wide bioactive spectrum, these positional isomers of isopropyl cresol deplete ergosterol content, compromise membrane permeability, block efflux pumps a...

journal_title：Microbial pathogenesis

authors： Khan A,Ahmad A,Ahmad Khan L,Padoa CJ,van Vuuren S,Manzoor N

更新日期：2015-03-01 00:00:00

abstract：:Present study evaluates the protective effect of mollugin against Klebsiella pneumonia (KP) and also postulates the possible mechanism of its action. Klebsiella pneumoniae (2.4 × 108 CFU/ml) was used for the induction of KP. PMNs and WBC count was determined in the blood and bronchoalveolar lavage fluid (BALF) of Kleb...

journal_title：Microbial pathogenesis

authors： Zhang Y,Zhou S,Zhou J,Wang D,Zhou T

更新日期：2019-07-01 00:00:00

abstract：:Viral myocarditis (VMC) is a type of inflammation affecting myocardial cells caused by viral infection and has been an important cause of dilated cardiomyopathy (DCM) worldwide. Type B3 coxsackievirus (CVB3), a non-enveloped positive-strand RNA virus of the Enterovirus genus, is one of most common agent of viral myoca...

journal_title：Microbial pathogenesis

authors： Zhao Y,Yan K,Wang Y,Cai J,Wei L,Li S,Xu W,Li M

更新日期：2020-07-01 00:00:00

abstract：CONTEXT:Hepatitis E virus (HEV) as a hepatotropic virus is one of the major global health concerns. Autochthonous HEV transmitted by oral fecal-route in poor sanitation conditions as well as vertical and rarely blood transfusion. HEV occurrence is more common in developing countries and recently increased in developed ...

journal_title：Microbial pathogenesis

authors： Karbalaie Niya MH,Rezaee-Zavareh MS,Ranaei A,Alavian SM

更新日期：2017-09-01 00:00:00

abstract：:The failure of drugs for effective treatment against infectious diseases can be attributed to resistant forms of causative agents. The evasive nature of Mycobacterium tuberculosis is partly associated to its physical features, such as having a thick cell wall and incorporation of beneficial mutations leading to drug r...

journal_title：Microbial pathogenesis

authors： Rabha A,Singh A,Grover S,Kumari A,Pandey B,Grover A

更新日期：2019-04-01 00:00:00

abstract：:Besides the well characterized role in glycolysis, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been implicated in virulence of pathogenic micro-organisms and because of its cell surface location, it has been shown to act as an adhesin for colonization of tissue surfaces both for pathogenic and non-pathogenic ...

journal_title：Microbial pathogenesis

authors： van der Merwe J,Prysliak T,Gerdts V,Perez-Casal J

更新日期：2011-06-01 00:00:00

abstract：:A cytotoxin to Vero cells (Shiga-like toxin), which was neutralized by antibody against purified Shiga toxin produced by Shigella dysenteriae 1, was purified from Escherichia coli O157:H7, isolated from a patient with hemorrhagic colitis. The purification procedure consisted of ammonium sulfate fractionation, DEAE-cel...

journal_title：Microbial pathogenesis

authors： Noda M,Yutsudo T,Nakabayashi N,Hirayama T,Takeda Y

更新日期：1987-05-01 00:00:00

abstract：:Until recently, glycoproteins had only been described in eukaryotes. However, advances in detection methods and genome analyses have allowed the discovery of N-linked or O-linked glycoproteins, similar to those found in eukaryotes, in some bacterial species. These prokaryotic glycoproteins play roles in adhesion, solu...

journal_title：Microbial pathogenesis

authors： Shoji M,Nakayama K

更新日期：2016-05-01 00:00:00

abstract：:Childhood pneumonia has been considered as a major cause of child morbidity and mortality worldwide. We aimed to investigate the effect of resveratral in synergizing with oral amoxicillin to improve the treatment outcome of oral amoxicillin administration against childhood fast breathing pneumonia. 647 children diagno...

journal_title：Microbial pathogenesis

authors： Qiang L,Di Y,Jiang Z,Xu J

更新日期：2018-01-01 00:00:00

abstract：:To determine if RecA plays a role in the virulence of Brucella abortus, a B. abortus RecA mutant was constructed and its survival was examined in mice. The recA gene was cloned from a B. abortus genomic DNA library by complementation of an Escherichia coli recA mutant in the presence of methyl methanesulfonate (MMS). ...

journal_title：Microbial pathogenesis

authors： Tatum FM,Morfitt DC,Halling SM

更新日期：1993-03-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is one of several opportunistic microbial pathogens associated with many healthcare problems. In the present study, S. aureus was assessed for its biofilm-forming ability on materials routinely used in dental offices, including stainless steel (SS), polyethylene (PE), and polyvinyl ch...

journal_title：Microbial pathogenesis

authors： Merghni A,Bekir K,Kadmi Y,Dallel I,Janel S,Bovio S,Barois N,Lafont F,Mastouri M

更新日期：2017-02-01 00:00:00

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:Animal studies with Candida albicans have provided models for understanding fungal virulence and antifungal drug development. To non-invasively monitor long-term Candida murine infections, clinical isolates were stably transformed with a codon-optimized luciferase gene to constitutively express luciferase. Chronic sys...

journal_title：Microbial pathogenesis

authors： Doyle TC,Nawotka KA,Kawahara CB,Francis KP,Contag PR

更新日期：2006-02-01 00:00:00

abstract：:The search for new antimicrobial drugs has been necessary due to the increased bacterial resistance to antibiotics currently in use, and natural products play an important role in this field. The aim of this study was to evaluate the in vitro effect of cinnamaldehyde on S. epidermidis strains, biofilm set-up preventio...

journal_title：Microbial pathogenesis

authors： Albano M,Crulhas BP,Alves FCB,Pereira AFM,Andrade BFMT,Barbosa LN,Furlanetto A,Lyra LPDS,Rall VLM,Júnior AF

更新日期：2019-01-01 00:00:00

abstract：:In this experimental study, the Allium essential oil (AHEO) was extracted through the hydrodistillation method. AHEO components were identified through gas chromatography/mass spectrometry (GC/MS), and its antioxidant properties and total phenolic content were examined through the methods of 2,2-diphenyl-1-picrylhydra...

journal_title：Microbial pathogenesis

authors： Alizadeh Behbahani B,Imani Fooladi AA

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study is to evaluate antidiarrheal activity of SKB_Gutbiotic against Castor oil and E.coli induced diarrhea in Swiss albino mice and Sprague Dawley rats. In present study three doses of SKB_Gutbiotic were tested against castor oil induced diarrhea in mice. Its effect on co-administration with l-arginin...

journal_title：Microbial pathogenesis

authors： Vanjari H,Mohan M,Saudagar P,Guthale G,Dalvi M

更新日期：2020-06-01 00:00:00

abstract：:Mannheimia(Pasteurella)haemolytica serotype 1 is the primary causative agent responsible for bovine pneumonic mannheimiosis, also known as shipping fever in cattle. The bacterium produces a variety of virulence factors, foremost of which is the exotoxic leukotoxin. The leukotoxin is a calcium-dependent cytolysin that ...

journal_title：Microbial pathogenesis

authors： Thumbikat P,Briggs RE,Kannan MS,Maheswaran SK

更新日期：2003-05-01 00:00:00

abstract：:3-Hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase (HMGR), an NADPH dependant enzyme catalyzes the synthesis of mevalonic acid from HMG-CoA required for isoprenoid biosynthesis. The HMGR gene from Leishmania donovani was cloned and expressed. Genome analysis of L. donovani revealed that HMGR gene having an open readin...

journal_title：Microbial pathogenesis

authors： Dinesh N,Pallerla DS,Kaur PK,Kishore Babu N,Singh S

更新日期：2014-01-01 00:00:00

abstract：:The live oral typhoid vaccine Ty21a has proved to confer protection against the disease at least as effectively as killed parenteral vaccines, whereas killed oral vaccines have not been protective in field trials. This prompted us to compare the immune response of subjects vaccinated either with live oral, killed oral...

journal_title：Microbial pathogenesis

authors： Kantele A,Arvilommi H,Kantele JM,Rintala L,Mäkelä PH

更新日期：1991-02-01 00:00:00

abstract：:Group A streptococci demonstrate a number of distinct ways to interact with the human fibrinolytic system to acquire unregulatable cell-surface enzymatic activity. Interactions between bacteria, fibrinogen, streptokinase and plasminogen resulted in acquisition of cell-associated enzymatic activity that can lyse fibrin...

journal_title：Microbial pathogenesis

authors： Wang H,Lottenberg R,Boyle MD

更新日期：1995-03-01 00:00:00