A novel cysteine proteinase (CP65) of Trichomonas vaginalis involved in cytotoxicity.

abstract：:A number of different techniques were used to analyse classic and atypical serogroup O:11 Aeromonas isolates. Five of seven atypical O:11, S layer-negative strains lacking a homogeneous LPS side-chain pattern exhibited varying degrees of mouse pathogenecity. One virulent atypical strain (AH-77) synthesized a surface a...

journal_title：Microbial pathogenesis

authors： Kokka RP,Vedros NA,Janda JM

更新日期：1991-01-01 00:00:00

abstract：:Viral myocarditis (VMC) is a type of inflammation affecting myocardial cells caused by viral infection and has been an important cause of dilated cardiomyopathy (DCM) worldwide. Type B3 coxsackievirus (CVB3), a non-enveloped positive-strand RNA virus of the Enterovirus genus, is one of most common agent of viral myoca...

journal_title：Microbial pathogenesis

authors： Zhao Y,Yan K,Wang Y,Cai J,Wei L,Li S,Xu W,Li M

更新日期：2020-07-01 00:00:00

abstract：:Application of antibiotics to combat bacterial diseases in fish has been criticized due to likely emergence of drug resistance. Therefore, investigation of new bioactive compounds from natural sources has been taken into account. This study was designed to purify and characterize the bioactive compound in the cell fre...

journal_title：Microbial pathogenesis

authors： Mukherjee A,Banerjee G,Mukherjee P,Ray AK,Chandra G,Ghosh K

更新日期：2019-05-01 00:00:00

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:The re-emerging field of phage therapy is the potential biocontrol agents for the transfer of virulence factor and to kill their bacterial hosts. In this study, the lytic Vibrio vulnificus phages were studied to provide a better understanding of phage-host interactions and development of phage therapy. Four new V. vul...

journal_title：Microbial pathogenesis

authors： Srinivasan P,Ramasamy P

更新日期：2017-10-01 00:00:00

abstract：:Interleukin-8 (IL-8) is a neutrophil and T-lymphocyte chemotactic and activating factor. This cytokine is produced by many cell types including macrophages in response to a variety of microbial and non-microbial agents. In the present study, we determined the nucleotide sequence for bovine IL-8 cDNA. The amino acid se...

journal_title：Microbial pathogenesis

authors： Morsey MA,Popowych Y,Kowalski J,Gerlach G,Godson D,Campos M,Babiuk LA

更新日期：1996-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is considered one of the most important causes of chronic liver diseases. Many reports have shown that the proteins of the HCV via interactions with gene expression regulatory networks such as cellular pathways and microRNAs can contribute to the development of chronic liver diseases....

journal_title：Microbial pathogenesis

authors： Khanizadeh S,Ravanshad M,Hosseini SY,Davoodian P,Almasian M,Khanlari Z

更新日期：2017-09-01 00:00:00

abstract：:The Guama virus (GMAV) is a member of Peribunyaviridae family, Orthobunyavirus genus. Several strains of the virus were isolated in South and Central Americas from several hosts, such as humans, wild animals, including nonhuman primates, wild rodents and mosquitoes as well as mice used as sentinels. The virus is able ...

journal_title：Microbial pathogenesis

authors： Matos GC,Ferreira MS,Martins Filho AJ,Amador Neto OP,Campos VM,Lima MLG,Rodrigues JCP,Ribeiro ACDS,Freitas MNO,Silva FA,Chiang JO,Casseb LMN,Sousa JR,Quaresma JAS,Martins LC,Vasconcelos PFDC,Carvalho VL

更新日期：2019-10-01 00:00:00

abstract：:Foot and Mouth disease (FMD) is economically devastating, highly contagious transboundry viral disease of livestock with 100% morbidity, rapid spread and severe production losses in animals. The FMDV has seven different serotypes. There is no vaccine that can protect animals from all serotypes. Hence, it is need of th...

journal_title：Microbial pathogenesis

authors： Raza S,Siddique K,Rabbani M,Yaqub T,Anjum AA,Ibrahim M,Azhar M,Jamil F,Rasheed MA

更新日期：2019-03-01 00:00:00

abstract：:Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected patients. Recent studies indicated that active glucagon like peptide-1 (GLP-1) encoded by glucagon (GCG) gene exer...

journal_title：Microbial pathogenesis

authors： Bai Y,Lian P,Li J,Zhang Z,Qiao J

更新日期：2020-12-05 00:00:00

abstract：:To determine if RecA plays a role in the virulence of Brucella abortus, a B. abortus RecA mutant was constructed and its survival was examined in mice. The recA gene was cloned from a B. abortus genomic DNA library by complementation of an Escherichia coli recA mutant in the presence of methyl methanesulfonate (MMS). ...

journal_title：Microbial pathogenesis

authors： Tatum FM,Morfitt DC,Halling SM

更新日期：1993-03-01 00:00:00

abstract：:Hemolysins are cytolytic proteins which have been extensively characterized at the molecular level, however, their in vivo functions remain unclear. This study analyzed the association of hemolysin production with the inflammatory response in patients with urinary tract infection (UTI). Infants and children with their...

journal_title：Microbial pathogenesis

authors： Connell H,de Man P,Jodal U,Lincoln K,Svanborg C

更新日期：1993-06-01 00:00:00

abstract：:Oxidative stress is implicated in the pathogenesis of influenza virus infection. Increasing evidences show that transient receptor potential melastatin 2 (TRPM2), a Ca2+-permeable non-selective cation channel, plays an important role in the pathomechanism of reactive oxygen species (ROS)-coupled diseases. The present ...

journal_title：Microbial pathogenesis

authors： Wang S,Liang T,Luo Q,Li P,Zhang R,Xu M,Su J,Xu T,Wu Q

更新日期：2020-11-01 00:00:00

abstract：:Periodontitis is a highly prevalent infective and inflammatory disease with an adverse impact on systemic health. Isorhamnetin, a flavonoid mainly isolated from Hippophae fhamnoides L. fruit, has been reported to have anti-inflammatory effect. This study aimed to investigate the anti-inflammatory effects and mechanism...

journal_title：Microbial pathogenesis

authors： Qi F,Sun JH,Yan JQ,Li CM,Lv XC

更新日期：2018-07-01 00:00:00

abstract：:Pathogenic Salmonella strains have a set of virulence factors allowing them to generate systemic infections and damage in a variety of hosts. Among these factors, bacterial proteins secreted by specialized systems are used to penetrate the host's intestinal mucosa, through the invasion and destruction of specialized e...

journal_title：Microbial pathogenesis

authors： Varas M,Ortíz-Severín J,Marcoleta AE,Díaz-Pascual F,Allende ML,Santiviago CA,Chávez FP

更新日期：2017-06-01 00:00:00

abstract：:Murine gammaherpesvirus 72 (MHV-72) is a virus of wild rodents and serves as a convenient small animal model to understand the pathogenesis of Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV8) infection. In laboratory mice MHV-72 causes an acute infection of lung epithelial cells and establishes the latency in B...

journal_title：Microbial pathogenesis

authors： Raslova H,Berebbi M,Rajcani J,Sarasin A,Matis J,Kudelova M

更新日期：2001-08-01 00:00:00

abstract：:Chronic burn wound infections caused by Stapyhylococcus aureus (S. aureus) are largely associated with biofilm formation. However, the mechanism by which S. aureus form biofilm in clinical environments is far less understood. In the present study we addressed the association between biofilm formation and membrane vesi...

journal_title：Microbial pathogenesis

authors： He X,Yuan F,Lu F,Yin Y,Cao J

更新日期：2017-09-01 00:00:00

abstract：:Clostridium perfringens (C. perfringens), a Gram-positive bacterium, is one of the main causing piglet diarrhea, which leads serious economic loss in the world swine industries. Generally, the innate immune response plays a critical role in host defense against pathogen invasion. TLR4, a member of the TLR (Toll-like r...

journal_title：Microbial pathogenesis

authors： Shi H,Huang X,Yan Z,Yang Q,Wang P,Li S,Sun W,Gun S

更新日期：2019-10-01 00:00:00

abstract：:Natural habitats of opportunistic fungal pathogens are outside of the host; therefore, it is critically important to understand their ecology and routes of transmission. In this study, we investigated the presence of human pathogenic opportunistic fungi in lake water and incidence of fungal infections in associated po...

journal_title：Microbial pathogenesis

authors： Bandh SA,Kamili AN,Ganai BA,Lone BA

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age. It shifts the paradigms of the vagina from healthy, beneficial microbiota to facultative and strict anaerobes. BV remains one of the most arduous and controversial challenges in modern-day clinical micr...

journal_title：Microbial pathogenesis

authors： Javed A,Manzoor S

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Tuberculosis (TB) is considered as a serious complication of organ transplant; therefore, the detection and appropriate treatment of active TB infection is highly recommended for the reduction of mortality in the future. The aim of this review was to conduct a systematic review and meta-analysis assessing ...

journal_title：Microbial pathogenesis

authors： Mamishi S,Pourakbari B,Moradzadeh M,van Leeuwen WB,Mahmoudi S

更新日期：2020-02-01 00:00:00

abstract：:Anthemis species are traditionally used to treat infectious and inflammatory processes, among others clinical disturbances. In the current study, the chemical composition, the total phenolic and flavonoid contents, the antioxidant, anticholinesterase, antimicrobial, and antibiofilm activities of Anthemis stiparum subs...

journal_title：Microbial pathogenesis

authors： Chemsa AE,Zellagui A,Öztürk M,Erol E,Ceylan O,Duru ME,Lahouel M

更新日期：2018-06-01 00:00:00

abstract：:Mannheimia(Pasteurella)haemolytica serotype 1 is the primary causative agent responsible for bovine pneumonic mannheimiosis, also known as shipping fever in cattle. The bacterium produces a variety of virulence factors, foremost of which is the exotoxic leukotoxin. The leukotoxin is a calcium-dependent cytolysin that ...

journal_title：Microbial pathogenesis

authors： Thumbikat P,Briggs RE,Kannan MS,Maheswaran SK

更新日期：2003-05-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae is the pathogen of porcine contagious pleuropneumonia causing great economic losses globally. LuxS is known to be involved in the interspecies quorum sensing by mediating the production of AI-2 signal molecule and play important roles in regulating various behaviors of bacteria. In this...

journal_title：Microbial pathogenesis

authors： Li L,Zhou R,Li T,Kang M,Wan Y,Xu Z,Chen H

更新日期：2008-09-01 00:00:00

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:YopM is a type III secretion effector from Yersinia which contributes to pathogenicity but whose action still remains unclear. It is an acidic, leucine-rich repeats (LRR) containing protein which migrates to the nucleus of target cells in spite of the fact that it does not contain any classical nuclear localization si...

journal_title：Microbial pathogenesis

authors： Benabdillah R,Mota LJ,Lützelschwab S,Demoinet E,Cornelis GR

更新日期：2004-05-01 00:00:00

abstract：:Clostridium difficile causes serious and potentially fatal inflammatory diseases of the colon. Two large protein toxins, TcdA and TcdB, have been clearly implicated in pathogenesis. The goal of this study was to determine whether the glucosyltransferase activity of the toxins is critical for the induction of tumor nec...

journal_title：Microbial pathogenesis

authors： Sun X,He X,Tzipori S,Gerhard R,Feng H

更新日期：2009-06-01 00:00:00

abstract：:The Phytophthora capsici inflicts damage on numerous crop plants by secreting a series of pectinase including pectin methylesterase (PME). We identified a PME gene (pcpme6) from a genomic library of a highly virulent P. capsici strain SD33 which had an encoded a polypeptide of 348 amino acid residues with a predicted ...

journal_title：Microbial pathogenesis

authors： Feng B,Li P,Wang H,Zhang X

更新日期：2010-07-01 00:00:00

abstract：:The present study was aimed to investigate and understand the mechanism of inhibitory effect of phenyl benzoxime on proliferation of SNU-306 cells. Proliferation of SNU-306 cells transfected with wild-type p53-induced phosphatase 1 (Wip1)-siRNA or treated with phenyl benzoxime was examined by 3-(4,5-dimethythiazol-2-y...

journal_title：Microbial pathogenesis

authors： Chen W,Tan Y,Zhang Y

更新日期：2019-01-01 00:00:00

abstract：:NorA, NorB, and NorC are efflux proteins in the Nor family that regulate the secretion of fluoroquinolones, and MgrA/NorR is a transcription factor of the Nor family. Overexpression of Nor family proteins provides fluoroquinolone resistance in Staphylococcus aureus. However, in coagulase-negative staphylococci (CNS), ...

journal_title：Microbial pathogenesis

authors： Juárez-Verdayes MA,Parra-Ortega B,Hernández-Rodríguez C,Betanzos-Cabrera G,Rodríguez-Martínez S,Cancino-Diaz ME,Cancino-Diaz JC

更新日期：2012-06-01 00:00:00