Identification and expression of nor efflux family genes in Staphylococcus epidermidis that act against gatifloxacin.

abstract：:The mechanism of Cronobacter pathogenesis in neonatal meningitis and potential virulence factors (aside from host cell invasion ability) remain largely unknown. To ascertain whether Cronobacter can invade and transcytose across intestinal epithelial cells, enter into the blood stream and then transcytose across the bl...

journal_title：Microbial pathogenesis

authors： Giri CP,Shima K,Tall BD,Curtis S,Sathyamoorthy V,Hanisch B,Kim KS,Kopecko DJ

更新日期：2012-02-01 00:00:00

abstract：:The major limitation in histological examination of orally inoculated mice of Salmonella typhimurium has been the difficulty of attaining high enough levels for immunochemical detection. This problem has been solved by the use of confocal laser scanning microscopy (CLSM) analysis, which allows detection of bacteria in...

journal_title：Microbial pathogenesis

authors： Matsui H,Eguchi M,Kikuchi Y

更新日期：2000-07-01 00:00:00

abstract：UNLABELLED:The outcome of Helicobacter pylori infection has been related to specific virulence-associated bacterial genotypes. The vacuolating cytotoxin (vacA), cagA gene, oipA and babA2 gene are important virulence factor involving gastric diseases. The objective of this study was to assess the relationship between vi...

journal_title：Microbial pathogenesis

authors： Salimzadeh L,Bagheri N,Zamanzad B,Azadegan-Dehkordi F,Rahimian G,Hashemzadeh-Chaleshtori M,Rafieian-Kopaei M,Sanei MH,Shirzad H

更新日期：2015-03-01 00:00:00

abstract：:Resistance to antimicrobials is a challenging issue that complicates the treatment of infections caused by bacteria and fungi, thus requiring new therapeutic options. Oncocalyxone A, a benzoquinone obtained from Auxemma oncocalyx (Allem) Taub has several biological effects; however, there is no data on its antimicrobi...

journal_title：Microbial pathogenesis

authors： da Silva RE,Ribeiro FOS,de Carvalho AMA,Daboit TC,Marinho-Filho JDB,Matos TS,Pessoa ODL,de Souza de Almeida Leite JR,de Araújo AR,Dos Santos Soares MJ

更新日期：2020-12-01 00:00:00

abstract：:Adhesion is the first step for Candida species to form biofilms on medical devices implanted in the human host. Both the physicochemical nature of the biomaterial and cell wall proteins (CWP) of the pathogen play a determinant role in the process. While it is true that some CWP have been identified in vitro, little is...

journal_title：Microbial pathogenesis

authors： Núñez-Beltrán A,López-Romero E,Cuéllar-Cruz M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:It is generally considered that HLA-Ⅱ genes contribute to the Helicobacter pylori (Hp) infection and disease development process. AIMS:To perform a meta-analysis to explore the relationship between HLA-Ⅱgene polymorphism and host susceptibility to Hp infection. METHODS:Relevant cohort studies, case-control...

journal_title：Microbial pathogenesis

authors： Wang J,Zhang Q,Liu Y,Han J,Ma X,Luo Y,Liang Y,Zhang L,Hu Y

更新日期：2015-05-01 00:00:00

abstract：:Infectious urinary stones account for about 10% of all urinary stones. In 50% of cases urolithiasis is a recurrent illness, which can lead to the loss of a kidney if not properly treated. One of the reasons for recurrence of the disease may be the ability of bacteria to invade urothelial cells, persist in the host cel...

journal_title：Microbial pathogenesis

authors： Torzewska A,Budzyńska A,Białczak-Kokot M,Różalski A

更新日期：2014-06-01 00:00:00

abstract：:Quorum sensing (QS), a cell-to-cell communication mechanism present in many bacterial species plays a key role in regulating the virulence factor and biofilm formation in many pathogens, which causes severe public health risk. Therefore, interfering with QS mechanism offers an attractive strategy to combat bacterial i...

journal_title：Microbial pathogenesis

authors： Vasavi HS,Sudeep HV,Lingaraju HB,Shyam Prasad K

更新日期：2017-03-01 00:00:00

abstract：:Upon oxygen shift-down, Mycobacterium tuberculosis complex bacteria can induce a genetic program characterized by halted duplication, which is called Non-replicating persistence (NRP). During this phase, at least 48 genes, collectively named Dormancy survival regulator (DosR) regulon, are important for the long-term s...

journal_title：Microbial pathogenesis

authors： Jiménez BA,Hinojoza-Loza E,Flores-Valdez MA,Prado-Montes de Oca E,Allen K,Estrada-Chávez C,Herrera-Rodríguez S,Flores-Fernández JM,Martínez-Velázquez M,Hernández-Gutiérrez R,Alvarez AH

更新日期：2013-08-01 00:00:00

abstract：:The emergence of extensively drug-resistant (XDR) Acinetobacter baumannii strains and the limited number of efficacious antibiotics demonstrate an urgent need to develop novel agents to treat infections caused by this dangerous pathogen. To find antimicrobial peptides against A. baumannii growing either in planktonic ...

journal_title：Microbial pathogenesis

authors： Irani N,Basardeh E,Samiee F,Fateh A,Shooraj F,Rahimi A,Shahcheraghi F,Vaziri F,Masoumi M,Pazhouhandeh M,Siadat SD,Kazemi-Lomedasht F,Jamnani FR

更新日期：2018-08-01 00:00:00

abstract：:We investigated the effects of vacuolating cytotoxin (VacA) prepared from Helicobacter pylori on the metabolism of gastric epithelial cells, AZ-521. VacA caused the ATP levels to decrease in a time-dependent manner; by approximately 20% in 6 h, 35% in 12 h and 50% in 24 h, at a concentration of 120 nM. This decrease w...

journal_title：Microbial pathogenesis

authors： Kimura M,Goto S,Wada A,Yahiro K,Niidome T,Hatakeyama T,Aoyagi H,Hirayama T,Kondo T

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:This study focused on the comparative genomic analyses of two qnrVC6 carrying Pseudomonas spp. strains which might give us insights on the similarity and difference in the genomic contexts of qnrVC6 gene. METHODS:Comparative genomic analyses of the novel qnrVC6 carrying Pseudomonas spp. genomes with emphasi...

journal_title：Microbial pathogenesis

authors： Liu J,Yang L,Li L,Li B,Chen D,Xu Z

更新日期：2018-10-01 00:00:00

abstract：:Programmed cell death is part of normal development and homeostasis. Apoptosis induced by bacteria appears to contribute to infectious diseases. Some bacteria produce toxins to kill host cells by the same pathway, apoptosis, through different mechanisms including pore formation, protein synthesis inhibition or adenyla...

journal_title：Microbial pathogenesis

authors： Chen Y,Zychlinsky A

更新日期：1994-10-01 00:00:00

abstract：:Salmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing sy...

journal_title：Microbial pathogenesis

authors： Almeida FA,Vargas ELG,Carneiro DG,Pinto UM,Vanetti MCD

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems and produces several virulence factors. The most important of these factors is biofilm. Many studies suggest administration of new generation of antibiotics, as P. aeruginosa biofilm has developed high resistance to antimicro...

journal_title：Microbial pathogenesis

authors： Dolatabadi S,Moghadam HN,Mahdavi-Ourtakand M

更新日期：2018-05-01 00:00:00

abstract：:Moritella viscosa is the aetiological agent of winter-ulcer disease in farmed salmonids in the North Atlantic. Previously, two major (typical and variant) genetic clades have been demonstrated within this bacterial species, one of which is almost solely related to disease in Atlantic salmon (Salmo salar). In the prese...

journal_title：Microbial pathogenesis

authors： Karlsen C,Ellingsen AB,Wiik-Nielsen C,Winther-Larsen HC,Colquhoun DJ,Sørum H

更新日期：2014-12-01 00:00:00

abstract：:Good vaccines should confer protection against specific pathogens in experimental and field conditions. However, some commercial vaccines are not capable to confer protection to animals, being inefficient in a bovine vaccine program. In this sense, the aim of this study was to evaluate the antibody levels involved in ...

journal_title：Microbial pathogenesis

authors： Fávero JF,Fritzen A,Lovato LT,Martins P,Baldissera MD,Stefani LM,Da Silva AS

更新日期：2018-01-01 00:00:00

abstract：:YopM is a type III secretion effector from Yersinia which contributes to pathogenicity but whose action still remains unclear. It is an acidic, leucine-rich repeats (LRR) containing protein which migrates to the nucleus of target cells in spite of the fact that it does not contain any classical nuclear localization si...

journal_title：Microbial pathogenesis

authors： Benabdillah R,Mota LJ,Lützelschwab S,Demoinet E,Cornelis GR

更新日期：2004-05-01 00:00:00

abstract：:This study aims to investigate whether IL-10 regulate decidual Treg cells apoptosis to reverse the abnormal pregnancy outcomes with Toxoplasma gondii (T. gondii) infection. Recombinant mouse IL-10 (rIL-10) treatment and IL-10 deficiency (IL-10(-/-)) abnormal pregnancy animal models with T. gondii infection were establ...

journal_title：Microbial pathogenesis

authors： Lao K,Zhao M,Li Z,Liu X,Zhang H,Jiang Y,Wang Y,Hu X

更新日期：2015-12-01 00:00:00

abstract：:Human leishmaniasis is a spectral disease that includes asymptomatic self-resolving infection, localized skin lesions, and progressive visceral leishmaniasis. With some overlap, visceral and cutaneous leishmaniasis are usually caused by different species of Leishmania. This review focuses on host responses to infectio...

journal_title：Microbial pathogenesis

authors： Wilson ME,Jeronimo SM,Pearson RD

更新日期：2005-04-01 00:00:00

abstract：:The extracellular hemolysin (AHH1) gene of Aeromonas hydrophila ATCC7966 was cloned into Charomid9-28 in Escherichia coli DH1, and its complete nucleotide sequence determined. Escherichia coli carrying this gene expressed an extracellular heat-labile hemolysin for rabbit red blood cells. The minimum size of the coding...

journal_title：Microbial pathogenesis

authors： Hirono I,Aoki T

更新日期：1991-09-01 00:00:00

abstract：:Ectoine, the most prominent osmolyte in nature, is a vital compatible solute present in halophilic bacterium. It protects the cellular biomolecules of the halophilic bacteria and retains their intrinsic function from extreme circumstances. In the current research, ectoine biosynthesis gene cluster (ectABC) in Bacillus...

journal_title：Microbial pathogenesis

authors： Anburajan L,Meena B,Sreelatha T,Vinithkumar NV,Kirubagaran R,Dharani G

更新日期：2019-11-01 00:00:00

abstract：:Neisseria meningitidis, but not Haemophilus influenzae, damage cultured human endothelial cells. We have undertaken a study to generate genetically and structurally defined lipopolysaccharide (LPS) mutant strains of meningococci for functional studies to assess the role of surface exposed oligosaccharides in imparting...

journal_title：Microbial pathogenesis

authors： Jennings MP,Bisercic M,Dunn KL,Virji M,Martin A,Wilks KE,Richards JC,Moxon ER

更新日期：1995-12-01 00:00:00

abstract：:As one of the dominant bacteria in the ocean, Vibrio play important roles in maintaining the aquatic ecosystem. In this study, we studied the phylogenetic relationships of 32 Vibrio based on the 16S rRNA genes sequences and utilized substrate immersing zymography method to detect the trend of protease production and c...

journal_title：Microbial pathogenesis

authors： Liu D,Wu C,Wu R,Huang J,Liao B,Lei M,Zhang Y,He H

更新日期：2019-06-01 00:00:00

abstract：:The biodegradation of Aflatoxin B1 (AFB1) is an industry of increasing importance. Bacillus licheniformis BL-010 was isolated from the aflatoxin contaminated corn feed storage, and was shown to degrade AFB1 efficiently. Here we present the complete genome sequence of BL-010, the genome comprises 4,287,714 bp in a circ...

journal_title：Microbial pathogenesis

authors： He S,Feng K,Ding T,Huang K,Yan H,Liu X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:During the past decade, cationic antimicrobial peptides (CAPs) have gained particular interest among researchers, since they often display broad-spectrum antimicrobial activity and low possibility of resistance emergence. This study aimed to investigate in vitro effectiveness of Mastoparan-1 (MP-1), a tetradecapeptide...

journal_title：Microbial pathogenesis

authors： Memariani H,Memariani M,Pourmand MR

更新日期：2018-06-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is one of several opportunistic microbial pathogens associated with many healthcare problems. In the present study, S. aureus was assessed for its biofilm-forming ability on materials routinely used in dental offices, including stainless steel (SS), polyethylene (PE), and polyvinyl ch...

journal_title：Microbial pathogenesis

authors： Merghni A,Bekir K,Kadmi Y,Dallel I,Janel S,Bovio S,Barois N,Lafont F,Mastouri M

更新日期：2017-02-01 00:00:00

abstract：:Staphylococcus aureus expresses many Microbial Surface Recognizing Adhesive Matrix Molecules (MSCRAMM's) to recognize host extracellular matrix (ECM) molecules to initiate colonization. The MSCRAMM, fibronectin binding protein A (FnBPA), is an important adhesin for S. aureus infection. FnBPA also binds with fibrinogen...

journal_title：Microbial pathogenesis

authors： Ponnuvel S,Sankar S,Ponnuraj K

更新日期：2020-09-01 00:00:00

abstract：:Establishment of pulmonary Mycobacterium tuberculosis infection requires evasion of host innate defenses. In the lung alveoli, epithelial cells naturally resist uptake by the inhaled bacilli while macrophages patrol the epithelial surface and phagocytose foreign microbes. Alveolar microvascular endothelial cells, howe...

journal_title：Microbial pathogenesis

authors： Mehta PK,Karls RK,White EH,Ades EW,Quinn FD

更新日期：2006-08-01 00:00:00

abstract：:Influenza A virus infection plays a significant role in the pathogenesis of Streptococcus pneumoniae-induced acute otitis media in children. An understanding of how influenza A virus modulates host cellular responses is critically important in efforts to explore the molecular mechanisms of this synergism. We used micr...

journal_title：Microbial pathogenesis

authors： Tong HH,Long JP,Li D,DeMaria TF

更新日期：2004-10-01 00:00:00