abstract：:Uropathogenic Escherichia coli (UPEC) is the most prevalent causative agent of urinary tract infections (UTIs). The pathogenicity of UPEC relies on the expression of virulence factors which could be regulated by intercellular signal molecules. Our previous study found that sub-minimal inhibitory concentration ceftazid...

journal_title：Microbial pathogenesis

authors： Feng W,Zhang L,Yuan Q,Wang Y,Yao P,Xia P,Sun F

更新日期：2021-01-21 00:00:00

abstract：:Saffron (Crocus sativus L.) is an important plant in medicine. The Kashmir Valley (J&K, India) is one of the world's largest and finest saffron producing regions. However, over the past decade, there has been a strong declining trend in saffron production in this area. Plant Growth Promoting Rhizobacteria (PGPR) are f...

journal_title：Microbial pathogenesis

authors： Rasool A,Imran Mir M,Zulfajri M,Hanafiah MM,Azeem Unnisa S,Mahboob M

更新日期：2021-01-08 00:00:00

abstract：:Based on the in-depth study of type III secretion systems (T3SS) in pathogenic bacteria, approaches targeting T3SS have become new alternative strategies to combat drug-resistant bacterial infections. As an important food-borne pathogen, Salmonella enterica serovar Typhimurium (S. Typhimurium) injects effector protein...

journal_title：Microbial pathogenesis

authors： Lv Q,Lv Y,Dou X,Wassy SL,Jia G,Wei L,Yu Q,Deng X,Zhang C,Wang J

更新日期：2021-01-05 00:00:00

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:A number of studies have identified that gut microbiota influences the development of cancer. However, there is little known about gut microbiota and esophageal cancer (EC). The aim of this study was to investigate the gut microbiota profile associated with EC. In this study, 23 patients with EC and 23 sex- and age-ma...

journal_title：Microbial pathogenesis

authors： Deng Y,Tang D,Hou P,Shen W,Li H,Wang T,Liu R

更新日期：2020-12-27 00:00:00

abstract：:Multidrug resistance due to the expression of extended spectrum β-lactamases (ESBLs) by bacterial pathogens is an alarming health concern with huge socio-economic burden. Here, 102 bacterial isolates from Wastewater treatment plants (WTPs) were screened for resistance to different antibiotics. Kirby-Bauer method and p...

journal_title：Microbial pathogenesis

authors： Hemlata,Bhat MA,Kumar V,Ahmed MZ,Alqahtani AS,Alqahtani MS,Jan AT,Rahman S,Tiwari A

更新日期：2020-12-08 00:00:00

abstract：:Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected patients. Recent studies indicated that active glucagon like peptide-1 (GLP-1) encoded by glucagon (GCG) gene exer...

journal_title：Microbial pathogenesis

authors： Bai Y,Lian P,Li J,Zhang Z,Qiao J

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Probiotics have been associated with many beneficial effects in human digestive physiology. The aim of this study was to evaluate the effect of improved formulation of chitosan-alginate microcapsules of Bifidobacterium strains on serum triglycerides, cholesterol, HDL, and LDL in mice. METHODS:Five approved ...

journal_title：Microbial pathogenesis

authors： Lohrasbi V,Abdi M,Asadi A,Rohani M,Esghaei M,Talebi M,Amirmozafari N

更新日期：2020-12-01 00:00:00

abstract：:The human microbiota gained a big interest among the scientific community with numerous studies being performed to better understand its role in health and diseases. Even with all the success achieved in studying the bacterial populations at the different body sites and its interaction among each other and with the ho...

journal_title：Microbial pathogenesis

authors： Bilen M

更新日期：2020-12-01 00:00:00

abstract：:In recent years, blast disease caused by Magnaporthe grisea, an ascomycete fungus is becoming a serious threat to pearl millet crop in India and worldwide. Due to the increase in virulent races of pathogen, blast disease management strategies seemed to be very limited. Hence, unraveling the occurrence of blast isolate...

journal_title：Microbial pathogenesis

authors： Adhikari S,Joshi SM,Athoni BK,Patil PV,Jogaiah S

更新日期：2020-12-01 00:00:00

abstract：:Pseudomonas aeruginosa is one of the most common opportunistic pathogens that cause biofilm-associated infections. Biofilm formation is partially regulated by the quorum sensing (QS) system, and quercetin can inhibit QS, biofilm formation and virulence factors. We therefore speculated that quercetin would inhibit the ...

journal_title：Microbial pathogenesis

authors： Ouyang J,Feng W,Lai X,Chen Y,Zhang X,Rong L,Sun F,Chen Y

更新日期：2020-12-01 00:00:00

abstract：:As an economic devastating virus, porcine reproductive and respiratory syndrome virus (PRRSV) has spread globally, and seriously hinders the healthy development of the swine industry worldwide. In recent years, however, recombinant PRRSV strains are continuously emerging, resulting in the death of a large number of pi...

journal_title：Microbial pathogenesis

authors： Song Z,Zhang Q,Chen Y,Shen H,Yang G,Jiang P,Chen JL,Lin L

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:DNA vaccine has emerged as a promising approach with potential for Tuberculosis (TB) prevention in adults. However, the mechanism behind DNA vaccines is still largely unknown. MATERIALS AND METHODS:Utilizing the CRISPR/Cas9 technique, we engineered Ag85A mutated dendritic cells (Ag85A-M-DCs) in which the Ag8...

journal_title：Microbial pathogenesis

authors： Zhai J,Gao W,Zhao L,Lu C

更新日期：2020-12-01 00:00:00

abstract：:Essential oils (EOs) obtained from aromatic plants are rich in natural components with interesting antimicrobial effects. The aim of this study was to evaluate the chemical composition of EOs extracted from Origanum majorana (OM-EO), Mentha suaveolens (MS-EO), Rosmarinus officinalis (RO-EO), Salvia officinalis (SO-EO)...

journal_title：Microbial pathogenesis

authors： Ed-Dra A,Filali FR,Lo Presti V,Zekkori B,Nalbone L,Bouymajane A,Trabelsi N,Lamberta F,Bentayeb A,Giuffrida A,Giarratana F

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Since the pre-transplant status affects the renal transplantation success and ultimately the survival rate, identifying the probable risk factors that increase the chance of BK virus replication in end-stage renal disease patients can be included in proposing proper surveillance guidelines during pre and pos...

journal_title：Microbial pathogenesis

authors： Pourkazemi A,Shenagari M,Monfared A,Hassankhani A,Chamaki FN,Khosravi M,Lebadi M,Ashrafkhani B

更新日期：2020-12-01 00:00:00

abstract：:Resistance to antimicrobials is a challenging issue that complicates the treatment of infections caused by bacteria and fungi, thus requiring new therapeutic options. Oncocalyxone A, a benzoquinone obtained from Auxemma oncocalyx (Allem) Taub has several biological effects; however, there is no data on its antimicrobi...

journal_title：Microbial pathogenesis

authors： da Silva RE,Ribeiro FOS,de Carvalho AMA,Daboit TC,Marinho-Filho JDB,Matos TS,Pessoa ODL,de Souza de Almeida Leite JR,de Araújo AR,Dos Santos Soares MJ

更新日期：2020-12-01 00:00:00

abstract：:Rhoptry proteins (ROPs) play a significant role in various stages of Toxoplasma gondii (T. gondii) life cycle, being critical for both invasion and intracellular survival. ROP38 is a key manipulator of host gene expression and has a function in tachyzoite to bradyzoite conversion. In this study, we've employed various...

journal_title：Microbial pathogenesis

authors： Nosrati MC,Ghasemi E,Shams M,Shamsinia S,Yousefi A,Nourmohammadi H,Javanmardi E,Kordi B,Majidiani H,Ghaffari AD,Shakarami F

更新日期：2020-12-01 00:00:00

abstract：AIMS:The main objective of the present study was to assess and compare the safety and inhibitory efficacy of Lactobacillus acidophilus against cholera toxin and shigatoxin production by measuring CTX-B and Stx1 expression level in Caco-2 cells exposed to Vibrio cholerae (as a non-invasive small intestine pathogens and ...

journal_title：Microbial pathogenesis

authors： Alamdary SZ,Bakhshi B

更新日期：2020-12-01 00:00:00

abstract：:Mycotoxins represent substantial challenges to the farming industry. These include toxins produced by Fusarium fungi, particularly trichothecenes (toxin T-2) and fumonisin (FB1). In the present study, we determined the effects of addition on Saccharomyces cerevisiae lysate (SCL) added to feed contaminated with T-2 and...

journal_title：Microbial pathogenesis

authors： Dazuk V,Boiago MM,Rolim G,Paravisi A,Copetti PM,Bissacotti BF,Morsch VM,Vedovatto M,Gazoni FL,Matte F,Gloria EM,Da Silva AS

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age. It shifts the paradigms of the vagina from healthy, beneficial microbiota to facultative and strict anaerobes. BV remains one of the most arduous and controversial challenges in modern-day clinical micr...

journal_title：Microbial pathogenesis

authors： Javed A,Manzoor S

更新日期：2020-12-01 00:00:00

abstract：:Thanks to the progress and decreasing costs in genome sequencing technologies, more than 250,000 bacterial genomes are currently available in public databases, covering most, if not all, of the major human-associated phylogenetic groups of these microorganisms, pathogenic or not. In addition, for many of them, sequenc...

journal_title：Microbial pathogenesis

authors： Anani H,Zgheib R,Hasni I,Raoult D,Fournier PE

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Blastocystis is one of the most common pathogens of the human intestine, caused by an emerging parasite, which can lead to severe symptoms and even death in immunocompromised patients. We aimed to determine the global prevalence of Blastocystosis infection in people with immunodeficiency. A systematic litera...

journal_title：Microbial pathogenesis

authors： Khorshidvand Z,Khazaei S,Amiri M,Taherkhani H,Mirzaei A

更新日期：2020-11-24 00:00:00

abstract：:Essential oils and their chemical constituents have been reported with well documented antimicrobial effects against a range of bacterial, fungal and viral pathogens. By definition, essential oils are a complex mixture of volatile organic compounds which are synthesized naturally in different parts of the plant as par...

journal_title：Microbial pathogenesis

authors： Wani AR,Yadav K,Khursheed A,Rather MA

更新日期：2020-11-16 00:00:00

abstract：:HPV persistent infection is a main event leading to the development of cervical intraepithelial neoplasia and cervical cancer. Earlier to distinguish HPV persistent and transient infection is meaningful but the methods are limited. This study used 16S rDNA sequencing to determine the cervicovaginal microbiota of HPV p...

journal_title：Microbial pathogenesis

authors： Qingqing B,Jie Z,Songben Q,Juan C,Lei Z,Mu X

更新日期：2020-11-15 00:00:00

abstract：:SARS-CoV-2 is a causative agent of Coronavirus disease-19 (COVID-19), which is considered as a fatal disease for public health apprehension worldwide. This pathogenic virus can present everywhere. As it is a virus it can extend easily and cause severe illness to humans. Hence, an efficient international attentiveness ...

journal_title：Microbial pathogenesis

authors： Divya M,Vijayakumar S,Chen J,Vaseeharan B,Durán-Lara EF

更新日期：2020-11-01 00:00:00

abstract：:Food-production animals were considered to be a major reservoir of antimicrobial-resistant bacteria and clinically relevant pathogens. The potential of commensal Escherichia coli from pigs as a source of opportunistic pathogens associated with extraintestinal infections in humans needs to be assessed. In this study, 1...

journal_title：Microbial pathogenesis

authors： Li Y,Ma X,Li C,Dai X,Zhang L

更新日期：2020-11-01 00:00:00

abstract：:A total of 54 positive blood aerobic cultures of suspected blood sepsis in neonates were purified, diagnosed and tested for antibiotic susceptibility. Six bacterial pathogens of Escherichia coli (10 isolates), Klebsiella pneumoniae (10 isolates), Haemophilus influenzae (4 isolates), Pseudomonas aeruginosa (3 isolates)...

journal_title：Microbial pathogenesis

authors： Gatea Kaabi SA,Musafer HK

更新日期：2020-11-01 00:00:00

abstract：:Oxidative stress is implicated in the pathogenesis of influenza virus infection. Increasing evidences show that transient receptor potential melastatin 2 (TRPM2), a Ca2+-permeable non-selective cation channel, plays an important role in the pathomechanism of reactive oxygen species (ROS)-coupled diseases. The present ...

journal_title：Microbial pathogenesis

authors： Wang S,Liang T,Luo Q,Li P,Zhang R,Xu M,Su J,Xu T,Wu Q

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) remains a major public health problem. SH3RF1 and SH3RF2 are candidate genes with multiple single-nucleotide polymorphisms (SNPs) that have the potential to participate in Mycobacterium infection via activation of the JNK signaling pathway. In this case-control study, we aimed to investigat...

journal_title：Microbial pathogenesis

authors： Chen H,Zhou J,Jiao L,Song J,Zhong H,Zhao Z,Meng Z,Lu X,Chen X,Zhang W,Ying B

更新日期：2020-10-28 00:00:00

abstract：:Toxoplasma gondii is an intracellular obligate parasitic protozoon that can infect all warm-blooded animals, causing zoonotic toxoplasmosis. So far, there is no commercial toxoplasmosis vaccine for human use. In the present study, we constructed a DNA vaccine cocktail which includes the surface protein (SAG1) and the ...

journal_title：Microbial pathogenesis

authors： Sun H,Li J,Xiao T,Huang XD,Wang LJ,Huang BC,Yin K,Liu GZ,Xu C,Wei QK

更新日期：2020-10-01 00:00:00

abstract：:Rice is an important food crop in the world, and rice blast is one of the major fungal diseases that cause large-scale rice yield reduction. This study aimed to investigate the antagonistic activity and its molecular mechanism of bacterial strain JK isolated from seeds of super hybrid rice 'Shenliangyou 5814' (Oryza s...

journal_title：Microbial pathogenesis

authors： Jing R,Li N,Wang W,Liu Y

更新日期：2020-10-01 00:00:00

abstract：:Lactobacillus fermentum KU200060 was isolated from watery kimchi and its probiotic characteristics were evaluated, including tolerance to artificial gastric acid and bile salt, production of enzymes, ability to adhere to HT-29 cells, and antibiotic susceptibility. The antibacterial and antibiofilm effects of L. fermen...

journal_title：Microbial pathogenesis

authors： Lim SM,Lee NK,Kim KT,Paik HD

更新日期：2020-10-01 00:00:00

abstract：:A. baumannii has been considered as Priority-I as suggested by the World Health Organization (WHO) and the most critical pathogenic microorganism for causing nosocomial infection in imunno-compromised hospital-acquired patients due to multi-drug resistance (MDR). In the current study, we utilized "Computer-aided ligan...

journal_title：Microbial pathogenesis

authors： Amera GM,Khan RJ,Pathak A,Jha RK,Muthukumaran J,Singh AK

更新日期：2020-10-01 00:00:00

abstract：:Chlamydia persistence is a viable but non-replicative stage, induced by several sub-lethal stressor agents, including beta-lactam antibiotics. So far, no data about the connection between doxycycline and chlamydial persistence has been described in literature. We investigated the ability of doxycycline to induce C. tr...

journal_title：Microbial pathogenesis

authors： Marangoni A,Zalambani C,Marziali G,Salvo M,Fato R,Foschi C,Re MC

更新日期：2020-10-01 00:00:00

abstract：:Over the past 50 years, fungal natural products have revolutionized medicine, yielding drugs which have enormous therapeutic potential. The aim of this study was to investigate the probable effect of marine fungal natural products on various skin pathogens. Initially, seventy natural extracts obtained from 35 differen...

journal_title：Microbial pathogenesis

authors： Agrawal S,Barrow CJ,Deshmukh SK

更新日期：2020-09-01 00:00:00

abstract：:Inflammasome activation is an important host response to infectious diseases, but the difference in inflammasome activation between typhoid fever and non-typhoidal Salmonella infection has been rarely studied. To determine whether inflammasome activation in macrophages after S. Typhi and S. Typhimurium infection is di...

journal_title：Microbial pathogenesis

authors： Lin HH,Chen HL,Janapatla RP,Chen CL,Chiu CH

更新日期：2020-09-01 00:00:00

abstract：:Staphylococcus aureus expresses many Microbial Surface Recognizing Adhesive Matrix Molecules (MSCRAMM's) to recognize host extracellular matrix (ECM) molecules to initiate colonization. The MSCRAMM, fibronectin binding protein A (FnBPA), is an important adhesin for S. aureus infection. FnBPA also binds with fibrinogen...

journal_title：Microbial pathogenesis

authors： Ponnuvel S,Sankar S,Ponnuraj K

更新日期：2020-09-01 00:00:00

abstract：:Microglial inflammation is the hallmark of S. aureus induced brain abscesses. Conventional antibiotic therapy could not regulate inflammation and the use of steroids in CNS infection remained controversial. To address this issue the effect of dexamethasone along with ciprofloxacin on microglial inflammation has been a...

journal_title：Microbial pathogenesis

authors： Dey R,Bishayi B

更新日期：2020-08-01 00:00:00

abstract：:Viral myocarditis (VMC) is a type of inflammation affecting myocardial cells caused by viral infection and has been an important cause of dilated cardiomyopathy (DCM) worldwide. Type B3 coxsackievirus (CVB3), a non-enveloped positive-strand RNA virus of the Enterovirus genus, is one of most common agent of viral myoca...

journal_title：Microbial pathogenesis

authors： Zhao Y,Yan K,Wang Y,Cai J,Wei L,Li S,Xu W,Li M

更新日期：2020-07-01 00:00:00

abstract：:Staphylococcus aureus is one of the major bacterial mastitis pathogens with significant effects on animal and human health. Some studies showed that S. aureus strains that infect different host species are genetically distinct, although most strains can infect a wide range of host species. However, there are no clearl...

journal_title：Microbial pathogenesis

authors： Vaughn JM,Abdi RD,Gillespie BE,Kerro Dego O

更新日期：2020-07-01 00:00:00