Mass spectrometric analysis of tobacco-specific hemoglobin adducts.

abstract：:Epidemiological studies report a small but positive association between short-term increases in airborne particulate matter and small increases in morbidity and mortality from respiratory and cardiovascular disease in urban areas. However, the lack of a mechanistic explanation to link particle exposure and human healt...

journal_title：Environmental health perspectives

authors： Holian A,Hamilton RF Jr,Morandi MT,Brown SD,Li L

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The presence of pharmaceuticals in aquatic environments and in drinking water has prompted significant public interest regarding potential adverse ecological effects and risks to human health. OBJECTIVES:The Environmental Health Summit held in North Carolina, 10-11 November 2008, explored the issues associa...

journal_title：Environmental health perspectives

authors： Rodriguez-Mozaz S,Weinberg HS

更新日期：2010-07-01 00:00:00

abstract：:Once a sign of modernization and growth, dams are often seen today as symbols of environmental and social devastation. Over 800,000 dams have been built worldwide to provide drinking water, flood control, hydropower, irrigation, navigation, and water storage. Dams do indeed provide these things,but at the cost of seve...

journal_title：Environmental health perspectives

authors： Joyce S

更新日期：1997-10-01 00:00:00

abstract：:We present a pilot study of individuals (liquidators) who were engaged in clean-up operations after the disaster at the nuclear power plant at Chernobyl in Ukraine. In the 10 years since the disaster, adverse health effects among exposed individuals have not been clearly defined. There is widespread fear of damage to ...

journal_title：Environmental health perspectives

authors： Fischbein A,Zabludovsky N,Eltes F,Grischenko V,Bartoov B

更新日期：1997-12-01 00:00:00

abstract：:Mammalian cells in culture have been used to study the genetic effects of physical and chemical agents. We have used Chinese hamster ovary (CHO) cells, clone K1-BH4, to quantify mutations at the X-linked, large (35 kb) hypoxanthine-guanine phosphoribosyltransferase (hprt) locus (the CHO/HPRT assay) induced by environm...

journal_title：Environmental health perspectives

authors： Hsie AW,Xu Z,Yu Y,An J,Meltz ML,Schwartz JL,Hrelia P

更新日期：1993-10-01 00:00:00

abstract：:A comprehensive environmental fate and effects testing program, sponsored by the Chemical Manufacturers Association (CMA) Phthalate Esters Program Panel, has been completed. Based on the results, a preliminary safety assessment has shown that all of the 14 commercially important phthalates tested have sufficiently hig...

journal_title：Environmental health perspectives

authors： Group EF Jr

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Although 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been associated with alterations in ovarian function and hormones in animals, it has not been studied in humans. On 10 July 1976, an explosion exposed residents of Seveso, Italy, to the highest levels of TCDD in a population. Twenty years later, we init...

journal_title：Environmental health perspectives

authors： Warner M,Eskenazi B,Olive DL,Samuels S,Quick-Miles S,Vercellini P,Gerthoux PM,Needham L,Patterson DG,Mocarelli P

更新日期：2007-03-01 00:00:00

abstract：:A system suitable for the detection of meiotic aneuploidy is described in which various different origins of the aneuploidy can be distinguished. Aneuploid meiotic products are detected as black disomic spores held in asci containing all the products of a single meiosis. Aneuploidy may result from nondisjunction or fr...

journal_title：Environmental health perspectives

authors： Bond DJ,McMillan L

更新日期：1979-08-01 00:00:00

abstract：:Although press reports indicate that the leakage of methyl isocyanate (MIC) on December 3, 1984, in Bhopal has led to an increase in spontaneous abortions, stillbirths, infant mortality, and fetal abnormalities, no clinical or experimental studies on the reproductive toxicity of MIC were reported in scientific journal...

journal_title：Environmental health perspectives

authors： Varma DR

更新日期：1987-06-01 00:00:00

abstract：:During 1992 and 1993 the Wisconsin Division of Health investigated five cases in which copper-contaminated drinking water was suspected of causing gastrointestinal upsets. Each of these case studies was conducted after our office was notified of high copper levels in drinking water or notified of unexplained illnesses...

journal_title：Environmental health perspectives

authors： Knobeloch L,Ziarnik M,Howard J,Theis B,Farmer D,Anderson H,Proctor M

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Although from a societal point of view a modal shift from car to bicycle may have beneficial health effects due to decreased air pollution emissions, decreased greenhouse gas emissions, and increased levels of physical activity, shifts in individual adverse health effects such as higher exposure to air pollu...

journal_title：Environmental health perspectives

authors： Johan de Hartog J,Boogaard H,Nijland H,Hoek G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are persistent chemicals that have been widely used as flame retardants in furniture, carpet padding, car seats, and other consumer products during the past three decades. OBJECTIVE:We examined whether in utero exposure to PBDEs is associated with child cognitive funct...

journal_title：Environmental health perspectives

authors： Chen A,Yolton K,Rauch SA,Webster GM,Hornung R,Sjödin A,Dietrich KN,Lanphear BP

更新日期：2014-08-01 00:00:00

abstract：:We include in this review an assessment of the formation, environmental fate, and mammalian and ecotoxicity of CW agent degradation products relevant to environmental and occupational health. These parent CW agents include several vesicants: sulfur mustards [undistilled sulfur mustard (H), sulfur mustard (HD), and an ...

journal_title：Environmental health perspectives

authors： Munro NB,Talmage SS,Griffin GD,Waters LC,Watson AP,King JF,Hauschild V

更新日期：1999-12-01 00:00:00

abstract：:N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. De...

journal_title：Environmental health perspectives

authors： King CM,Glowinski IB

更新日期：1983-03-01 00:00:00

abstract：:The distribution of inhaled mineral fibers in the lung determines the site and severity of disease caused by the fibers. Some of our recent work has described the fate of inhaled asbestos fibers in rodents. After a brief inhalation exposure, asbestos fibers are deposited primarily at the first alveolar duct bifurcatio...

journal_title：Environmental health perspectives

authors： Coin PG,Roggli VL,Brody AR

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Adapting to extreme heat is becoming more critical as our climate changes. Previous research reveals that very few communities in the United States have programs to sufficiently prevent health problems during hot weather. OBJECTIVE:Our goal was to examine county-level local heat preparedness and response in...

journal_title：Environmental health perspectives

authors： White-Newsome JL,Ekwurzel B,Baer-Schultz M,Ebi KL,O'Neill MS,Anderson GB

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) may affect fetal growth; however, prior research often lacked assessment of mercury speciation, confounders, and interactions. OBJECTIVE:Our objective was to assess the relationship between MeHg and fetal growth as well as the potential for confounding or interaction of this relationshi...

journal_title：Environmental health perspectives

authors： Wells EM,Herbstman JB,Lin YH,Jarrett J,Verdon CP,Ward C,Caldwell KL,Hibbeln JR,Witter FR,Halden RU,Goldman LR

更新日期：2016-03-01 00:00:00

abstract：:The last decade has marked a radical change in the business of sustainability, say environmental activists and industrialists alike. On the wane are "greenwashing" campaigns in which corporations promote dubious environmental accomplishments to draw attention away from environmentally damaging practices. On the rise a...

journal_title：Environmental health perspectives

authors： Fields S

更新日期：2002-03-01 00:00:00

abstract：:Lead-induced nephropathy produces both tubular and interstitial manifestations of cell injury, but the pathophysiology of these lesions is not completely understood. Delineation of the molecular factors underlying renal handling of lead is one of central importance in understanding the mechanisms of renal cell injury ...

journal_title：Environmental health perspectives

authors： Fowler BA,DuVal G

更新日期：1991-02-01 00:00:00

abstract：:We have developed and applied a new measurement methodology to investigate dermal absorption of chloroform while bathing. Ten subjects bathed in chlorinated water while breathing pure air through a face mask. Their exhaled breath was delivered to a glow discharge source/ion trap mass spectrometer for continuous real-t...

journal_title：Environmental health perspectives

authors： Gordon SM,Wallace LA,Callahan PJ,Kenny DV,Brinkman MC

更新日期：1998-06-01 00:00:00

abstract：:Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies demonstrated that male BD IX rats consuming diets containing 50 ppm fumonisin B1 developed hepatocellular carcinomas. In our recent studies, diets containing FB1 at 50 ...

journal_title：Environmental health perspectives

authors： Howard PC,Warbritton A,Voss KA,Lorentzen RJ,Thurman JD,Kovach RM,Bucci TJ

更新日期：2001-05-01 00:00:00

abstract：:A biodosimetric approach to determine alpha-particle dose to the respiratory tract epithelium from known exposures to radon has been developed in the rat. Cytotoxicity assays have been used to obtain dose-conversion factors for cumulative exposures typical of those encountered by underground uranium miners. However, t...

journal_title：Environmental health perspectives

authors： Johnson NF,Carpenter TR,Jaramillo RJ,Liberati TA

更新日期：1997-06-01 00:00:00

abstract：:This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...

journal_title：Environmental health perspectives

authors： Baranski B

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Understanding the potential links between extreme weather events and human health in India is important in the context of vulnerability and adaptation to climate change. Research exploring such linkages in India is sparse. OBJECTIVES:We evaluated the association between extreme precipitation and gastrointes...

journal_title：Environmental health perspectives

authors： Bush KF,O'Neill MS,Li S,Mukherjee B,Hu H,Ghosh S,Balakrishnan K

更新日期：2014-03-01 00:00:00

abstract：:High-dose boric acid (BA) exposure produces testicular lesions in adult rats characterized by inhibited spermiation (IS) that may progress to atrophy. In vivo and in vitro studies addressed possible mechanisms. In vivo, boron tissue disposition was examined, since no detailed data existed, and relevant boron concentra...

journal_title：Environmental health perspectives

authors： Ku WW,Chapin RE

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. OBJECTIVES:We examined the short-term temperature-su...

journal_title：Environmental health perspectives

authors： Kim Y,Kim H,Gasparrini A,Armstrong B,Honda Y,Chung Y,Ng CFS,Tobias A,Íñiguez C,Lavigne E,Sera F,Vicedo-Cabrera AM,Ragettli MS,Scovronick N,Acquaotta F,Chen BY,Guo YL,Seposo X,Dang TN,de Sousa Zanotti Stagliorio Coel

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are flame retardants found in North American household products during the past four decades. These chemicals leach out in dust as products age, exposing individuals daily through inhalation and ingestion. Animal studies suggest that PBDEs disrupt sex hormones and adver...

journal_title：Environmental health perspectives

authors： Goodyer CG,Poon S,Aleksa K,Hou L,Atehortua V,Carnevale A,Koren G,Jednak R,Emil S,Bagli D,Dave S,Hales BF,Chevrier J

更新日期：2017-05-26 00:00:00

abstract：BACKGROUND:Chronic exposure to arsenic (As), a human toxicant and carcinogen, remains a global public health problem. Health risks persist after As exposure has ended, suggesting epigenetic dysregulation as a mechanistic link between exposure and health outcomes. OBJECTIVES:We investigated the association between tota...

journal_title：Environmental health perspectives

authors： Bozack AK,Domingo-Relloso A,Haack K,Gamble MV,Tellez-Plaza M,Umans JG,Best LG,Yracheta J,Gribble MO,Cardenas A,Francesconi KA,Goessler W,Tang WY,Fallin MD,Cole SA,Navas-Acien A

更新日期：2020-06-01 00:00:00

abstract：:comments on S. Patandin et al. : Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long-term exposure. Environ Health Perspect 107:45-51 (1999). ...

journal_title：Environmental health perspectives

authors： LaKind JS,Filser JG

更新日期：1999-10-01 00:00:00

abstract：:The remarkable frequency of uterine leiomyoma in the human population calls into question the potential for the participation of environmental factors in tumor etiology. Having been implicated in the dramatic rise in hormone-related cancers in recent years, endocrine disruptors are salient suspects in this pathogenesi...

journal_title：Environmental health perspectives

authors： Hunter DS,Hodges LC,Eagon PK,Vonier PM,Fuchs-Young R,Bergerson JS,Walker CL

更新日期：2000-10-01 00:00:00