Serum dioxin concentrations and quality of ovarian function in women of Seveso.

abstract：:Differential CYP1A1 inducibility, reflecting variations in aromatic hydrocarbon receptor (AHR) affinity among inbred mouse strains, is an important determinant of environmental toxicity. We took advantage of the Ahr polymorphism in C57BL/6 and DBA/2 mice to develop an oligonucleotide-hybridization screening approach f...

journal_title：Environmental health perspectives

authors： Maier A,Micka J,Miller K,Denko T,Chang CY,Nebert DW,Alvaro Puga

更新日期：1998-07-01 00:00:00

abstract：:We present a pilot study of individuals (liquidators) who were engaged in clean-up operations after the disaster at the nuclear power plant at Chernobyl in Ukraine. In the 10 years since the disaster, adverse health effects among exposed individuals have not been clearly defined. There is widespread fear of damage to ...

journal_title：Environmental health perspectives

authors： Fischbein A,Zabludovsky N,Eltes F,Grischenko V,Bartoov B

更新日期：1997-12-01 00:00:00

abstract：:Comamonas testosteroni YZW-D was isolated from Passaic River sediment for its ability to degrade isophthalate and terephthalate. Degradation of the two isomeric compounds proceeds via separately inducible catabolic pathways that converge at protocatechuate. Analysis of the catabolic pathways by which these two isomers...

journal_title：Environmental health perspectives

authors： Wang YZ,Zhou Y,Zylstra GJ

更新日期：1995-06-01 00:00:00

abstract：:Neurogenic inflammation as a pathway distinct from antigen-driven, immune-mediated inflammation may play a pivotal role in understanding a broad class of environmental health problems resulting from chemical exposures. Recent progress in understanding the mediators, triggers, and regulation of neurogenic inflammation ...

journal_title：Environmental health perspectives

authors： Meggs WJ

更新日期：1993-08-01 00:00:00

abstract：:Human DNA adduct formation (covalent modification of DNA with chemical carcinogens) is a promising biomarker for elucidating the molecular epidemiology of cancer. Classes of compounds for which human DNA adducts have been observed include polycyclic aromatic hydrocarbons (PAHs), nitrosamines, mycotoxins, aromatic amin...

journal_title：Environmental health perspectives

authors： Poirier MC,Weston A

更新日期：1996-10-01 00:00:00

abstract：:A combined cytogeneticurine metabolite analysis approach was used to assess potential interactive effects between Fenarimol (FN), a fungicide, and trichloroethylene (TRI), a halogenated solvent. FN was demonstrated to selectively induce P450-2B1 isoforms in different organs of treated mice. Since the rate of metabolis...

journal_title：Environmental health perspectives

authors： Hrelia P,Maffei F,Vigagni F,Fimognari C,Flori P,Stanzani R,Cantelli Forti G

更新日期：1994-11-01 00:00:00

abstract：:In this paper we report yields, identities, and mutagenicities of products from heating a polycyclic aromatic hydrocarbon (PAH)-contaminated, Superfund-related synthetic soil matrix without exogenous oxygen. We heated batch samples of soil pretreated with 5.08 wt% (by weight) pyrene in a tubular furnace under a consta...

journal_title：Environmental health perspectives

authors： Richter H,Risoul V,Lafleur AL,Plummer EF,Howard JB,Peters WA

更新日期：2000-08-01 00:00:00

abstract：:Relative advantages and disadvantages and important design criteria for various exposure methods are presented. Five types of exposures are discussed: whole-body chambers, head-only exposures, nose or mouth-only methods, lung-only exposures, and partial-lung exposures. Design considerations covered include: air cleani...

journal_title：Environmental health perspectives

authors： Phalen RF

更新日期：1976-08-01 00:00:00

abstract：:There is accumulating evidence that the multistage carcinogenic process is associated with the progressive acquisition of mutations in cellular proto-oncogenes and in growth-suppressor genes. At the same time, several types of evidence indicate that nongenotoxic agents and epigenetic events also play an important role...

journal_title：Environmental health perspectives

authors： Weinstein IB

更新日期：1991-06-01 00:00:00

abstract：:The presence of blue-green algae (BGA) toxins in surface waters used for drinking water sources and recreation is receiving increasing attention around the world as a public health concern. However, potential risks from exposure to these toxins in contaminated health food products that contain BGA have been largely ig...

journal_title：Environmental health perspectives

authors： Gilroy DJ,Kauffman KW,Hall RA,Huang X,Chu FS

更新日期：2000-05-01 00:00:00

abstract：:Multiple chemical sensitivity (MCS) is a condition in which persons experience negative health effects in multiple organ systems from exposure to low levels of common chemicals. Although symptoms experienced from particular chemicals vary across persons, they are generally stable within persons. The sensitivities ofte...

journal_title：Environmental health perspectives

authors： Gibson PR,Elms AN,Ruding LA

更新日期：2003-09-01 00:00:00

abstract：:Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns ...

journal_title：Environmental health perspectives

authors： Landrigan PJ,Suk WA,Amler RW

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Controversy remains regarding the relationship between ambient ozone and mortality worldwide. In mainland China, the largest developing country, there has been no prior study investigating the acute effect of O3 on death risk. Given the changes in types of air pollution from conventional coal combustion to t...

journal_title：Environmental health perspectives

authors： Zhang Y,Huang W,London SJ,Song G,Chen G,Jiang L,Zhao N,Chen B,Kan H

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Perfluoroalkyl substances (PFAS) may affect body mass index (BMI) and other components of cardiometabolic (CM) risk during childhood, but evidence is scarce and inconsistent. OBJECTIVES:We estimated associations between prenatal PFAS exposures and outcomes relevant to cardiometabolic risk, including a compo...

journal_title：Environmental health perspectives

authors： Manzano-Salgado CB,Casas M,Lopez-Espinosa MJ,Ballester F,Iñiguez C,Martinez D,Romaguera D,Fernández-Barrés S,Santa-Marina L,Basterretxea M,Schettgen T,Valvi D,Vioque J,Sunyer J,Vrijheid M

更新日期：2017-09-20 00:00:00

abstract：:A wide variety of behavioral methods has been employed with animals to assess visual changes induced by drugs or toxicants. The methods range from simple to complex, from broad screening devices to narrowly focused techniques. Their relative advantages for the environmental toxicologist are discussed. Manipulation of ...

journal_title：Environmental health perspectives

authors： Evans HL

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Tetraethyl lead was phased out of gasoline in Uganda in 2005. Recent mitigation of an important source of lead exposure suggests examination and re-evaluation of the prevalence of childhood lead poisoning in this country. Ongoing concerns persist about exposure from the Kiteezi landfill in Kampala, the count...

journal_title：Environmental health perspectives

authors： Graber LK,Asher D,Anandaraja N,Bopp RF,Merrill K,Cullen MR,Luboga S,Trasande L

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

journal_title：Environmental health perspectives

authors： Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

更新日期：2018-04-26 00:00:00

abstract：:Atmospheric pollution from vehicular traffic is a matter of growing interest, often leading to temporary restrictions in urban areas. Although guidelines indicate limits for several parameters, the real toxicologic impacts remain largely unexplored in field conditions. In this study our aim was to validate an ecotoxic...

journal_title：Environmental health perspectives

authors： Regoli F,Gorbi S,Fattorini D,Tedesco S,Notti A,Machella N,Bocchetti R,Benedetti M,Piva F

更新日期：2006-01-01 00:00:00

abstract：:Cooking, heat processing, or pyrolysis of protein-rich foods induce the formation of a series of structurally related heterocyclic aromatic bases that have been found to be mutagens. The primary genetic assay utilized to detect and isolate these mutagens has been the his reversion assay in Salmonella typhimurium. The ...

journal_title：Environmental health perspectives

authors： Hatch FT

更新日期：1986-08-01 00:00:00

abstract：:Chronic exposure of rodents to high dose levels of drugs, food additives and environmental chemicals frequently results in liver enlargement. Several of these compounds have been found to enhance the incidence of liver tumors in animals briefly exposed previously to hepatocarcinogens. Accordingly, it has been advanced...

journal_title：Environmental health perspectives

authors： Kunz HW,Tennekes HA,Port RE,Schwartz M,Lorke D,Schaude G

更新日期：1983-04-01 00:00:00

abstract：:We present a model to plan a rational strategy for cancer prevention that has two main functions--assessment and intervention. The assessment function includes three main components: to identify populations at high cancer risk, which may be due to their ethnic group, occupational and environmental exposures, family hi...

journal_title：Environmental health perspectives

authors： Anton-Culver H

更新日期：1995-11-01 00:00:00

abstract：:Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of human cancer caused by exposure to nonionizing radiation and may play a mechanistic role in the phenomenon of radioresistan...

journal_title：Environmental health perspectives

authors： Garte SJ,Burns FJ

更新日期：1991-06-01 00:00:00

abstract：:In 1998, the Helicobacter pylori [(13)C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in t...

journal_title：Environmental health perspectives

authors： Herbarth O,Krumbiegel P,Fritz GJ,Richter M,Schlink U,Müller DM,Richter T

更新日期：2001-06-01 00:00:00

abstract：:The type II cell plays an important role in the response of the alveolar epithelium after lung injury through its synthesis and secretion of pulmonary surfactant, and by acting as the stem cell for the replacement of damaged type I epithelial cells. The nonciliated bronchiolar epithelial (Clara) cell is thought to pla...

journal_title：Environmental health perspectives

authors： Finkelstein JN,Johnston C,Barrett T,Oberdörster G

更新日期：1997-09-01 00:00:00

abstract：:The purpose of this study was to examine whether perinatal exposure to two major environmental endocrine-disrupting chemicals, bisphenol A (BPA; 0.1 mg/kg/day orally) and nonylphenol [NP; 0.1 mg/kg/day (low dose) and 10 mg/kg/day (high dose) orally] daily from gestational day 3 to postnatal day 20 (transplacental and ...

journal_title：Environmental health perspectives

authors： Negishi T,Kawasaki K,Suzaki S,Maeda H,Ishii Y,Kyuwa S,Kuroda Y,Yoshikawa Y

更新日期：2004-08-01 00:00:00

abstract：:Forty percent of hazardous waste sites in the United States are co-contaminated with organic and metal pollutants. Data from both aerobic and anaerobic systems demonstrate that biodegradation of the organic component can be reduced by metal toxicity. Metal bioavailability, determined primarily by medium composition/so...

journal_title：Environmental health perspectives

authors： Sandrin TR,Maier RM

更新日期：2003-06-01 00:00:00

abstract：:In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. In recent years their actual advantages and limitations have been better defined. The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions...

journal_title：Environmental health perspectives

authors： Guillouzo A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. OBJECTIVES:We examined the short-term temperature-su...

journal_title：Environmental health perspectives

authors： Kim Y,Kim H,Gasparrini A,Armstrong B,Honda Y,Chung Y,Ng CFS,Tobias A,Íñiguez C,Lavigne E,Sera F,Vicedo-Cabrera AM,Ragettli MS,Scovronick N,Acquaotta F,Chen BY,Guo YL,Seposo X,Dang TN,de Sousa Zanotti Stagliorio Coel

更新日期：2019-11-01 00:00:00

abstract：:We used real-time monitors and low-volume air samplers to measure the potential human exposure to airborne polycyclic aromatic hydrocarbon (PAH) concentrations during various flight-related and ground-support activities of C-130H aircraft at an Air National Guard base. We used three types of photoelectric aerosol sens...

journal_title：Environmental health perspectives

authors： Childers JW,Witherspoon CL,Smith LB,Pleil JD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Studies estimating health effects of long-term air pollution exposure often use a two-stage approach: building exposure models to assign individual-level exposures, which are then used in regression analyses. This requires accurate exposure modeling and careful treatment of exposure measurement error. OBJEC...

journal_title：Environmental health perspectives

authors： Bergen S,Sheppard L,Sampson PD,Kim SY,Richards M,Vedal S,Kaufman JD,Szpiro AA

更新日期：2013-09-01 00:00:00