Abstract:
:During 1992 and 1993 the Wisconsin Division of Health investigated five cases in which copper-contaminated drinking water was suspected of causing gastrointestinal upsets. Each of these case studies was conducted after our office was notified of high copper levels in drinking water or notified of unexplained illnesses. Our findings suggest that drinking water that contains copper at levels above the federal action limit of 1.3 mg/l may be a relatively common cause of diarrhea, abdominal cramps, and nausea. These symptoms occurred most frequently in infants and young children and among resident of newly constructed or renovated homes.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Knobeloch L,Ziarnik M,Howard J,Theis B,Farmer D,Anderson H,Proctor Mdoi
10.1289/ehp.94102958subject
Has Abstractpub_date
1994-11-01 00:00:00pages
958-61issue
11eissn
0091-6765issn
1552-9924journal_volume
102pub_type
杂志文章abstract::One of the many forms that biological warfare may take is the targeting of major food crops. In a poor country where millions of citizens depend on staple crops such as rice, an act of bioterrorism that destroys the crop would create a famine, resulting not only in malnutrition and starvation but also in reduced immun...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.108-a126
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Arsenic (As) occurs as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in humans, and the methylation pattern demonstrates large interindividual differences. The fraction of urinary MMA is a marker for susceptibility to As-related diseases. OBJECTIVES:We evaluated the impact of polymorphisms in ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,随机对照试验
doi:10.1289/ehp.1002471
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Because of complex interactions of climate variables at the levels of the pathogen, vector, and host, the potential influence of climate change on vector-borne and zoonotic diseases (VBZDs) is poorly understood and difficult to predict. Climate effects on the nonvector-borne zoonotic diseases are especially ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.0901389
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Adapting to extreme heat is becoming more critical as our climate changes. Previous research reveals that very few communities in the United States have programs to sufficiently prevent health problems during hot weather. OBJECTIVE:Our goal was to examine county-level local heat preparedness and response in...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1306693
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:A growing body of evidence indicates a relationship between household indoor air pollution from cooking fires and adverse neonatal outcomes, such as low birth weight (LBW), in resource-poor countries. OBJECTIVE:We examined the effect of reduced wood smoke exposure in pregnancy on LBW of Guatemalan infants i...
journal_title:Environmental health perspectives
pub_type: 杂志文章,随机对照试验
doi:10.1289/ehp.1002928
更新日期:2011-10-01 00:00:00
abstract::There are still many uncertainties regarding the risk of adverse pregnancy outcomes associated with exposure to drinking water disinfection by-products. In Montréal, Québec, Canada, we carried out a hospital-based case-control study including 493 cases of intrauterine growth restriction defined as birth weight below t...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7003
更新日期:2004-08-01 00:00:00
abstract::Metals continually rank at the top of the U.S. Environmental Protection Agency's annual list of agents that pose the greatest hazard to the people of the United States. Metals aren't going away, either. They do not biodegrade, and they often concentrate in human and animal cells and tissue. Many metals are known human...
journal_title:Environmental health perspectives
pub_type: 新闻
doi:10.1289/ehp.99107a244
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/EHP483
更新日期:2017-06-13 00:00:00
abstract::A wide range of chemicals with diverse structures derived from plant and environmental origins are reported to have hormonal activity. The potential for appreciable exposure of humans to such substances prompts the need to develop sensitive screening methods to quantitate and evaluate the risk to the public. Yeast cel...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.97105734
更新日期:1997-07-01 00:00:00
abstract::The gas phase reactions of carbanions with molecular oxygen in both its ground state (X3 sigma g-) and first electronically excited state (a1 delta g) have been studied by the flowing afterglow technique. Reactions include cleavage processes, charge transfer, hydride transfer, formation of hydroxide ion and processes ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8036119
更新日期:1980-06-01 00:00:00
abstract::Exposure to air polluted with particles less than 2.5 micron in size is associated epidemiologically with adverse cardiopulmonary health consequences in humans. The goal of this study was to characterize human pulmonary responses to controlled experimental high-dose exposure to fine and ultrafine magnesium oxide parti...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.971051234
更新日期:1997-11-01 00:00:00
abstract::For workers in the nuclear industry, the primary route for the entry of radioactive materials into the body is by inhalation, and the rate of clearance of particles from the pulmonary region of the lung is an important factor in determining radiation dose. It is the function of alveolar macrophages (AM) to maintain th...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.929769
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Environmental air pollutants are inhaled as complex mixtures, but the long dominant focus of monitoring and research on individual pollutants has provided modest insight into pollutant interactions that may be important to health. Trends toward managing multiple pollutants to maximize aggregate health gains ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.11654
更新日期:2009-01-01 00:00:00
abstract::Metabolic enzymes involved in benzene activation or detoxification, including NAD(P)H, quinone oxidoreductase 1 (NQO1), cytochrome P450 2E1 (CYP2E1), myeloperoxidase (MPO), glutathione-S-transferase mu-1 (GSTM1), and glutathione-S-transferase theta-1 (GSTT1), were studied for their roles in human susceptibility to ben...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.021101213
更新日期:2002-12-01 00:00:00
abstract::We conducted experiments to determine whether diesel engine exhaust affects reproductive endocrine function in growing rats. The rats were assigned to three groups: a group exposed to total diesel engine exhaust containing 5.63 mg/m3 particulate matter, 4.10 ppm nitrogen dioxide, and 8.10 ppm nitrogen oxide; a group e...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.99107539
更新日期:1999-07-01 00:00:00
abstract::Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7234
更新日期:2004-12-01 00:00:00
abstract::Dysmenorrhea is a common gynecologic disorder in women of reproductive age. Previous studies have found an association between current cigarette smoking and prevalence of dysmenorrhea. This study investigated the association between exposure to environmental tobacco smoke (ETS) and the occurrence of dysmenorrhea among...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.001081019
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Controversy remains regarding the relationship between ambient ozone and mortality worldwide. In mainland China, the largest developing country, there has been no prior study investigating the acute effect of O3 on death risk. Given the changes in types of air pollution from conventional coal combustion to t...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9014
更新日期:2006-08-01 00:00:00
abstract::Uranium accumulates in bone, affects bone metabolism in laboratory animals, and when ingested in drinking water increases urinary excretion of calcium and phosphate, important components in the bone structure. However, little is known about bone effects of ingested natural uranium in humans. We studied 146 men and 142...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7475
更新日期:2005-01-01 00:00:00
abstract::Although press reports indicate that the leakage of methyl isocyanate (MIC) on December 3, 1984, in Bhopal has led to an increase in spontaneous abortions, stillbirths, infant mortality, and fetal abnormalities, no clinical or experimental studies on the reproductive toxicity of MIC were reported in scientific journal...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8772153
更新日期:1987-06-01 00:00:00
abstract::This study was undertaken to explore the effects of chronic low-level cadmium ingestion in Dahl hypertension-resistant (R) and hypertension-sensitive (S) lines of rats. Groups of weanling female R and S rats were given 0 or 1 mg cadmium/1. in drinking water and fed either a low salt (0.4% NaCl) or a high salt (4% NaCl...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7928261
更新日期:1979-02-01 00:00:00
abstract:INTRODUCTION:Ambient particulate pollution and traffic have been linked to myocardial infarction and cardiac death risk. Possible mechanisms include autonomic cardiac dysfunction. METHODS:In a repeated-measures study of 46 patients 43-75 years of age, we investigated associations of central-site ambient particulate po...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.0901003
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Most studies on endocrine-disrupting chemicals and breast cancer have focused on single compounds and have produced inconclusive findings. OBJECTIVES:We assessed the combined estrogenic effects of mixtures of xenoestrogens in serum and their relationship to breast cancer risk. METHODS:A total of 186 incide...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/EHP157
更新日期:2016-10-01 00:00:00
abstract::Organophosphates in increasing amounts and wider varieties of molecular structure are being used to replace the organochlorine pesticides. It has been assumed that the organophosphates as a class would have a minimal chronic toxicity due to rapid hydrolysis and an unfavorable partitioning as regards to lipids. The phy...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.761377
更新日期:1976-02-01 00:00:00
abstract::This paper summarizes the clinical phenomenology of multiple chemical sensitivity (MCS), outlines the concepts and evidence for the olfactory-limbic, neural sensitization model for MCS, and discusses experimental design implications of the model for exposure-related research. Neural sensitization is the progressive am...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.97105s2457
更新日期:1997-03-01 00:00:00
abstract::Concentrations of polychlorinated biphenyls (PCBs), hydroxylated metabolites of PCBs (HO-PCBs) and octachlorostyrene (4-HO-HpCS), and pentachlorophenol (PCP) were determined in umbilical cord plasma samples from three different regions of Québec. The regions studied included two coastal areas where exposure to PCBs is...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.02110411
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:The World Health Organization (WHO) released the fourth edition of Guidelines for Drinking-Water Quality in July 2011. In this edition, the 400-µg/L drinking-water guideline for manganese (Mn) was discontinued with the assertion that because "this health-based value is well above concentrations of manganese ...
journal_title:Environmental health perspectives
pub_type: 历史文章,杂志文章
doi:10.1289/ehp.1104693
更新日期:2012-06-01 00:00:00
abstract::The effects of global change on biodiversity and ecosystem functioning encompass multiple complex dynamic processes. Climate change and exposure to endocrine-disrupting chemicals (EDCs) are currently regarded as two of the most serious anthropogenic threats to biodiversity and ecosystems. We should, therefore, be espe...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.8057
更新日期:2006-04-01 00:00:00
abstract::Asthma is the most common chronic illness of childhood and its prevalence is increasing, causing much concern for identification of risk factors such as air pollution. We previously conducted a study showing a relationship between asthma visits in all persons < 65 years of age to emergency departments (EDs) and air po...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.99107489
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Exposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway. OBJECTIVES:We examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children. METHODS:We condu...
journal_title:Environmental health perspectives
pub_type: 杂志文章,随机对照试验
doi:10.1289/ehp.10882
更新日期:2008-05-01 00:00:00