Alveolar macrophage kinetics after inhalation of 239PuO2 by CBA/Ca mice: changes in synthesis of DNA.

abstract：BACKGROUND:Adverse cardiorespiratory health is associated with exposure to ambient particulate matter (PM). The highest PM concentrations in London occur in proximity to waste transfer stations (WTS), sites that experience high numbers of dust-laden, heavy-duty diesel vehicles transporting industrial and household wast...

journal_title：Environmental health perspectives

authors： Godri KJ,Duggan ST,Fuller GW,Baker T,Green D,Kelly FJ,Mudway IS

更新日期：2010-04-01 00:00:00

abstract：:Minority populations face a wide variety of economic, institutional, and cultural barriers to health care. These barriers and low levels of education and income pose significant challenges for health professionals in developing cancer research and prevention-control strategies. It is suggested that specific segments o...

journal_title：Environmental health perspectives

authors： Ramirez AG,McAlister A,Gallion KJ,Villarreal R

更新日期：1995-11-01 00:00:00

abstract：:The purpose of the investigation is to study whether an increased mortality from certain causes exists in an area around the Rönnskärsverken smelter works in northern Sweden. Founded in 1928, this metallurgical plant processing mainly nonferrous metals has since its initial operations been using ore with a high arseni...

journal_title：Environmental health perspectives

authors： Pershagen G,Elinder CG,Bolander AM

更新日期：1977-08-01 00:00:00

abstract：:Preterm delivery can lead to serious infant health outcomes, including death and lifelong disability. Small increases in preterm delivery risk in relation to spatial gradients of air pollution have been reported, but previous studies may have controlled inadequately for individual factors. Using a time-series analysis...

journal_title：Environmental health perspectives

authors： Sagiv SK,Mendola P,Loomis D,Herring AH,Neas LM,Savitz DA,Poole C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The upward trend in industrial nations in the incidence of male genitourinary (GU) conditions may be attributed to increased exposure to endocrine disruptors. Polybrominated biphenyl (PBB), a brominated flame retardant, is one such suspected endocrine disruptor. OBJECTIVE:We investigated the relationship be...

journal_title：Environmental health perspectives

authors： Small CM,DeCaro JJ,Terrell ML,Dominguez C,Cameron LL,Wirth J,Marcus M

更新日期：2009-07-01 00:00:00

abstract：:Martineau et al. (2002) reported that St. Lawrence beluga (SLB) have high cancer rates. Unfortunately, errors in their interpretation of the data have led them to overstate the importance of cancer and its links to environmental sources. ...

journal_title：Environmental health perspectives

authors： Hammill MO,Lesage V,Kingsley MC

更新日期：2003-02-01 00:00:00

abstract：:In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrin...

journal_title：Environmental health perspectives

authors： Mossman BT,Faux S,Janssen Y,Jimenez LA,Timblin C,Zanella C,Goldberg J,Walsh E,Barchowsky A,Driscoll K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Tetraethyl lead was phased out of gasoline in Uganda in 2005. Recent mitigation of an important source of lead exposure suggests examination and re-evaluation of the prevalence of childhood lead poisoning in this country. Ongoing concerns persist about exposure from the Kiteezi landfill in Kampala, the count...

journal_title：Environmental health perspectives

authors： Graber LK,Asher D,Anandaraja N,Bopp RF,Merrill K,Cullen MR,Luboga S,Trasande L

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Health risks differ by fine particle (aerodynamic diameter ≤ 2.5 μm) component, although with substantial variability. Traditional methods to assess component-specific risks are limited, suggesting the need for alternative methods. OBJECTIVES:We examined whether the odds of daily hospital admissions differ ...

journal_title：Environmental health perspectives

authors： Suh HH,Zanobetti A,Schwartz J,Coull BA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Exposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway. OBJECTIVES:We examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children. METHODS:We condu...

journal_title：Environmental health perspectives

authors： Thompson B,Coronado GD,Vigoren EM,Griffith WC,Fenske RA,Kissel JC,Shirai JH,Faustman EM

更新日期：2008-05-01 00:00:00

abstract：:Droplets of toluene and three chlorinated organics, ortho-dichlorobenzene, 1,2-dichloroethane, and trichloroethylene, were pyrolyzed in pure nitrogen. The composition and bacterial mutagenicity of the product tars were measured. The presence of organic chlorine was found to affect both pyrolysis product tar compositio...

journal_title：Environmental health perspectives

authors： Mulholland JA,Sarofim AF,Longwell JP,Lafleur AL,Thilly WG

更新日期：1994-01-01 00:00:00

abstract：:Considerable attention has been given to the relationship between levels of fine particulate matter (particulate matter < or = 2.5 microm in aerodynamic diameter; PM(2.5) in the atmosphere and health effects in human populations. Since the U.S. Environmental Protection Agency began widespread monitoring of PM(2.5) lev...

journal_title：Environmental health perspectives

authors： Holloman CH,Bortnick SM,Morara M,Strauss WJ,Calder CA

更新日期：2004-09-01 00:00:00

abstract：:Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little known. We studied their effects on two main targets, the renal and dopaminergic systems, in > 800 children during a cross-sectional European survey. Control and ...

journal_title：Environmental health perspectives

authors： de Burbure C,Buchet JP,Leroyer A,Nisse C,Haguenoer JM,Mutti A,Smerhovsky Z,Cikrt M,Trzcinka-Ochocka M,Razniewska G,Jakubowski M,Bernard A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The 1974 Safe Drinking Water Act (SDWA) regulates >170,000 public water systems to protect health, but not >13 million private wells. State and local government requirements for private well water testing are rare and inconsistent; the responsibility to ensure water safety remains with individual households....

journal_title：Environmental health perspectives

authors： Zheng Y,Flanagan SV

更新日期：2017-08-03 00:00:00

abstract：:Previously, we showed that diesel exhaust particles (DEPs) suppressed pulmonary clearance of Listeria monocytogenes (Listeria) and inhibited the phagocytosis of alveolar macrophages and their response to Listeria in the secretion of interleukin (IL)-1 beta, tumor necrosis factor alpha, and IL-12. In this report we exa...

journal_title：Environmental health perspectives

authors： Yin XJ,Schafer R,Ma JY,Antonini JM,Roberts JR,Weissman DN,Siegel PD,Ma JK

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about exposure mixtures, including methods such as weighted quantile sum (WQS) regression that estimate a joint effect o...

journal_title：Environmental health perspectives

authors： Keil AP,Buckley JP,O'Brien KM,Ferguson KK,Zhao S,White AJ

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Cadmium exposure may increase the risk of cardiovascular disease. The only published longitudinal study on cadmium and incident cardiovascular disease was performed in American Indians with relatively high cadmium exposure. OBJECTIVES:Our aim was to examine the association between blood cadmium at baseline ...

journal_title：Environmental health perspectives

authors： Barregard L,Sallsten G,Fagerberg B,Borné Y,Persson M,Hedblad B,Engström G

更新日期：2016-05-01 00:00:00

abstract：:Surface IR (infrared) modes of crystalline and fumed (amorphous) silica particles, calcined at temperatures up to 1095 degrees C, have been studied by Fourier transform infrared spectroscopy. The ability of these same particles to lyse cells has been measured by a hemolysis protocol. The untreated crystalline and amor...

journal_title：Environmental health perspectives

authors： Pandurangi RS,Seehra MS,Razzaboni BL,Bolsaitis P

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Pesticides have been associated with Parkinson's disease (PD), but there are few data on important exposure characteristics such as dose-effect relations. It is unknown whether associations depend on clinical PD subtypes. OBJECTIVES:We examined quantitative aspects of occupational pesticide exposure associa...

journal_title：Environmental health perspectives

authors： Moisan F,Spinosi J,Delabre L,Gourlet V,Mazurie JL,Bénatru I,Goldberg M,Weisskopf MG,Imbernon E,Tzourio C,Elbaz A

更新日期：2015-11-01 00:00:00

abstract：:The ability of questionnaires to predict children's exposure to pesticides was examined as part of the Minnesota Children's Pesticide Exposure Study (MNCPES). The MNCPES focused on a probability sample of 102 children between the ages of 3 and 13 years living in either urban (Minneapolis and St. Paul, MN) or nonurban ...

journal_title：Environmental health perspectives

authors： Sexton K,Adgate JL,Eberly LE,Clayton CA,Whitmore RW,Pellizzari ED,Lioy PJ,Quackenboss JJ

更新日期：2003-01-01 00:00:00

abstract：:Most contemporary bioinsecticides are derived from scaled-up cultures of Bacillus thuringiensis subspecies israelensis (Bti) and kurstaki (Btk), whose particulate fractions contain mostly B. thuringiensis spores (> 10(12)/L) and proteinaceous aggregates, including crystal-like parasporal inclusion bodies (PIB). Based ...

journal_title：Environmental health perspectives

authors： Tayabali AF,Seligy VL

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The autonomic nervous system plays a key role in maintaining homeostasis and responding to external stimuli. In adults, exposure to fine particulate matter ( PM ...

journal_title：Environmental health perspectives

authors： Cowell WJ,Brunst KJ,Malin AJ,Coull BA,Gennings C,Kloog I,Lipton L,Wright RO,Enlow MB,Wright RJ

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. OBJECTIVE:We investigated the impact of tolerated and toxic arsenic trioxide (As2O3) e...

journal_title：Environmental health perspectives

authors： Rahman S,Housein Z,Dabrowska A,Mayán MD,Boobis AR,Hajji N

更新日期：2015-05-01 00:00:00

abstract：:Recent increases have been reported in industrial countries for several sites of cancer. The causes of these increases remain unknown. Efforts should proceed to identify those occupational groups with increases in the same sites, as these may indicate relevant exposures. Two analyses were undertaken: trends in cancer ...

journal_title：Environmental health perspectives

authors： Davis DL,Blair A,Hoel DG

更新日期：1993-04-01 00:00:00

abstract：:Between 1966 and 1986, the childhood leukemia rate in Woburn, Massachusetts, was 4-fold higher than the national average. A multidisciplinary research team from MIT, which is being supported by the NIEHS Superfund Basic Research Program, has explored the possible importance of a temporal correlation between the period...

journal_title：Environmental health perspectives

authors： Durant JL,Chen J,Hemond HF,Thilly WG

更新日期：1995-09-01 00:00:00

abstract：:The presence of low concentrations of perchlorate in some drinking water sources has led to concern regarding potential effects on the thyroid. In a recently published report, the National Academy of Sciences indicated that the perchlorate dose required to cause hypothyroidism in adults would probably be > 0.40 mg/kg-...

journal_title：Environmental health perspectives

authors： Crump KS,Gibbs JP

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. OBJECTIVE:We aimed to assess the toxicity of well-characte...

journal_title：Environmental health perspectives

authors： Bastian S,Busch W,Kühnel D,Springer A,Meissner T,Holke R,Scholz S,Iwe M,Pompe W,Gelinsky M,Potthoff A,Richter V,Ikonomidou C,Schirmer K

更新日期：2009-04-01 00:00:00

abstract：:The review of over 800 references on aluminum (Al) published since the mid-fifties covers the occurrence of Al in soil, air, water, plants and food products, as well as air and water pollution problems. In addition, the existing quality criteria, the biology and toxicology of Al, and the therapeutic and medical uses a...

journal_title：Environmental health perspectives

authors： Sorenson JR,Campbell IR,Tepper LB,Lingg RD

更新日期：1974-08-01 00:00:00

abstract：:This working paper summarizes the known ultrastructural and biochemical effects of lead, mercury, cadmium, and arsenic on subcellular organelle systems following in vivo administration. Documented metal-induced alterations in nuclear, mitochondrial, microsomal, and lysosomal functions are discussed in relation to thei...

journal_title：Environmental health perspectives

authors： Fowler BA

更新日期：1978-02-01 00:00:00

abstract：:Effects of respirable aerosols of sulfuric acid, ammonium sulfate, sodium sulfite, and ammonium persulfate on lungs of rats are reviewed. The literature regarding interactions between ozone or nitrogen dioxide and acidic aerosols (ammonium sulfate, sulfuric acid) is discussed. An unexpected interaction between nitroge...

journal_title：Environmental health perspectives

authors： Last JA

更新日期：1989-02-01 00:00:00