Surface and bulk infrared modes of crystalline and amorphous silica particles: a study of the relation of surface structure to cytotoxicity of respirable silica.

abstract：BACKGROUND:Humans have been exposed to fine and ultrafine particles throughout their history. Since the Industrial Revolution, sources, doses, and types of nanoparticles have changed dramatically. In the last decade, the rapidly developing field of nanotechnology has led to an increase of engineered nanoparticles with ...

journal_title：Environmental health perspectives

authors： Wick P,Malek A,Manser P,Meili D,Maeder-Althaus X,Diener L,Diener PA,Zisch A,Krug HF,von Mandach U

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Cancer may be a stem cell (SC)-based disease involving formation of cancer SCs (CSCs) potentially arising from transformation of normal SCs. Cadmium has been linked to human pancreatic cancer. OBJECTIVE:We studied cadmium exposure of human pancreatic ductal epithelial (HPDE) cells and whether SCs may be tar...

journal_title：Environmental health perspectives

authors： Qu W,Tokar EJ,Kim AJ,Bell MW,Waalkes MP

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exposure has been linked to an increased risk of coronary heart disease (CHD). Paraoxonase 1 (PON1), an enzyme located in the high-density-lipoprotein (HDL) fraction of blood lipids, may protect against CHD by metabolizing toxic oxidized lipids associated with low-density liproprotein an...

journal_title：Environmental health perspectives

authors： Ayotte P,Carrier A,Ouellet N,Boiteau V,Abdous B,Sidi EA,Château-Degat ML,Dewailly É

更新日期：2011-08-01 00:00:00

abstract：:Inoculation of tumorigenic prostatic stroma and nontumorigenic prostatic epithelia into the subcutaneous space of syngeneic rats induced the development of carcinosarcoma. The induced tumors, which were composed of a mixture of adenocarcinoma and fibrosarcoma, were androgen responsive. This model offers a novel mechan...

journal_title：Environmental health perspectives

authors： Chung LW,Chang SM,Bell C,Zhau H,Ro JY,von Eschenbach AC

更新日期：1988-04-01 00:00:00

abstract：:Atlantic coast estuaries recently have experienced fish kills and fish with lesions attributed to Pfiesteria piscicida and related dinoflagellates. Human health effects have been reported from laboratory exposure and from a 1997 Maryland fish kill. North Carolina has recorded Pfiesteria-related fish kill events over t...

journal_title：Environmental health perspectives

authors： Swinker M,Koltai D,Wilkins J,Hudnell K,Hall C,Darcey D,Robertson K,Schmechel D,Stopford W,Music S

更新日期：2001-01-01 00:00:00

abstract：:There are a number of technical and statistical problems in monitoring the temporal and spatial variation of local area death rates in the United States for evidence of systematically elevated risks. An analytic strategy is proposed to reduce one of the major statistical concerns, i.e., that of identifying areas with ...

journal_title：Environmental health perspectives

authors： Manton KG,Stallard E,Creason JP,Riggan WB

更新日期：1985-05-01 00:00:00

abstract：:Basophilic hepatic foci, nodules, and trabecular hepatocellular carcinomas, collectively referred to as focal hepatic lesions, were induced by single injections of 5.0 micrograms of diethylnitrosamine (DEN) per gram body weight in 15-day-old C57BL/6J X C3HeB/FeJ F1 (B6C3 F1) mice. Groups of eight experimental and eigh...

journal_title：Environmental health perspectives

authors： Goldfarb S,Pugh TD,Koen H,He YZ

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Arsenic, cadmium, mercury, and lead are associated with cardiovascular disease in epidemiologic research. These associations may be mediated by direct effects of the metals on blood pressure (BP) elevation. Manganese is associated with cardiovascular dysfunction and hypotension in occupational cohorts. OBJE...

journal_title：Environmental health perspectives

authors： Mordukhovich I,Wright RO,Hu H,Amarasiriwardena C,Baccarelli A,Litonjua A,Sparrow D,Vokonas P,Schwartz J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In a changing climate, increasing temperatures are anticipated to have profound health impacts. These impacts could be mitigated if individuals and communities adapt to changing exposures; however, little is known about the extent to which the population may be adapting. OBJECTIVE:We investigated the hypoth...

journal_title：Environmental health perspectives

authors： Bobb JF,Peng RD,Bell ML,Dominici F

更新日期：2014-08-01 00:00:00

abstract：:Soil ingestion estimates play an important role in risk assessment of contaminated sites, and estimates of soil ingestion in children are of special interest. Current estimates of soil ingestion are trace-element specific and vary widely among elements. Although expressed as daily estimates, the actual estimates have ...

journal_title：Environmental health perspectives

authors： Stanek EJ 3rd,Calabrese EJ

更新日期：1995-03-01 00:00:00

abstract：:New technologies are providing innovative ways to reduce sound levels in many areas. Aircraft engineers are finding ways to reduce the noise produced by jet engines, while road builders are using rubber-enhanced pavement to quiet highway noise. Indoor acoustics are benefiting from materials that transform sound waves ...

journal_title：Environmental health perspectives

authors： Manuel J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains undefined. OBJECTIVES:O...

journal_title：Environmental health perspectives

authors： Negro Silva LF,Lemaire M,Lemarié CA,Plourde D,Bolt AM,Chiavatti C,Bohle DS,Slavkovich V,Graziano JH,Lehoux S,Mann KK

更新日期：2017-07-05 00:00:00

abstract：:The role of the knowledge of high risk groups in the standard-setting process is examined. The overall conclusion is that many potential high risk segments of the population have not been studied adequately and that this deficiency in our knowledge markedly reduces the ability of decision makers to derive appropriate ...

journal_title：Environmental health perspectives

authors： Calabrese EJ

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Miners inhaling respirable coal dust (CD) frequently develop coal workers' pneumoconiosis, a dust-associated pneumoconiosis characterized by lung inflammation and variable fibrosis. Many coal miners are also exposed to polycyclic aromatic hydrocarbon (PAH) components of diesel engine exhaust and cigarette sm...

journal_title：Environmental health perspectives

authors： Ghanem MM,Battelli LA,Mercer RR,Scabilloni JF,Kashon ML,Ma JY,Nath J,Hubbs AF

更新日期：2006-09-01 00:00:00

abstract：:Unlike laboratory animals, people are rarely exposed to a single hazardous chemical. However, most of the information documenting adverse human health effects from environmental and occupational contaminants has come from studies focused on exposure to single chemicals, and there is little information available on how...

journal_title：Environmental health perspectives

authors： Carpenter DO,Arcaro KF,Bush B,Niemi WD,Pang S,Vakharia DD

更新日期：1998-12-01 00:00:00

abstract：:Many mutagenic heterocyclic amines (HAs) have been isolated from cooked foods and pyrolysates of amino acids and proteins, and the carcinogenicity of 10 of these HAs in rodents and of 1 in monkeys has been reported. Quantification of these carcinogenic HAs in various kinds of cooked foods indicated that the level of 2...

journal_title：Environmental health perspectives

authors： Wakabayashi K,Ushiyama H,Takahashi M,Nukaya H,Kim SB,Hirose M,Ochiai M,Sugimura T,Nagao M

更新日期：1993-03-01 00:00:00

abstract：:The ability of a series of haloalkanes, haloethanols and haloacetaldehydes to induce mutations in Salmonella typhrimurium and preferentially to inhibit the growth of DNA polymerase-deficient E. coli (pol A(+)/pol A(-)) was investigated. For the haloalkanes investigated, the order of reactivities towards the E. coli po...

journal_title：Environmental health perspectives

authors： Rosenkranz HS

更新日期：1977-12-01 00:00:00

abstract：:The epidemiological data linking air pollution and lung cancer are derived from statistical associations concerning rates of cancer among urban and rural residents, migrant studies and studies of occupational groups exposed to effluents from fossil fuel combinations. Few, if any of these studies, are adequately adjust...

journal_title：Environmental health perspectives

authors： Speizer FE

更新日期：1983-01-01 00:00:00

abstract：:Scientists at Pacific Northwest National Laboratory in Richland, Washington, have developed a unique imaging system capable of focusing on a single living cell within an organism. This new technology will be used in what the multidisciplinary team has termed a "cellular observatory" to study the effect of environmenta...

journal_title：Environmental health perspectives

authors： Medlin J

更新日期：1999-11-01 00:00:00

abstract：:A brief overview is given of the sources, characteristics, and toxic constituents of municipal solid wastes. Several methods are presented for handling, treating, and disposal of solid wastes. Monitoring the landfill site is necessary; there has been a trend to recognize that municipal solid wastes may be hazardous an...

journal_title：Environmental health perspectives

authors： Stone R

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Phthalates may pose a risk for perinatal developmental effects. An important question relates to the choice of suitable biological matrices for assessing exposure during this period. OBJECTIVES:This study was designed to measure the concentrations of phthalate diesters or their metabolites in breast milk, b...

journal_title：Environmental health perspectives

authors： Högberg J,Hanberg A,Berglund M,Skerfving S,Remberger M,Calafat AM,Filipsson AF,Jansson B,Johansson N,Appelgren M,Håkansson H

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS:We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at ter...

journal_title：Environmental health perspectives

authors： Lederman SA,Jones RL,Caldwell KL,Rauh V,Sheets SE,Tang D,Viswanathan S,Becker M,Stein JL,Wang RY,Perera FP

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Particulate matter (PM) in outdoor air pollution was recently designated a Group I carcinogen by the International Agency for Research on Cancer (IARC). This determination was based on the evidence regarding the relationship of PM2.5 and PM10 to lung cancer risk; however, the IARC evaluation did not include ...

journal_title：Environmental health perspectives

authors： Hamra GB,Guha N,Cohen A,Laden F,Raaschou-Nielsen O,Samet JM,Vineis P,Forastiere F,Saldiva P,Yorifuji T,Loomis D

更新日期：2014-09-01 00:00:00

abstract：:Okadaic acid, dinophysistoxin-1 (35-methylokadaic acid), and calyculin A are the okadaic acid class of non-12-O-tetradecanoylphorbol-13-acetate (TPA)-type tumor promoters, which do not bind to the phorbol ester receptors in cell membranes or activate protein kinase C in vitro. They have potent tumor-promoting activiti...

journal_title：Environmental health perspectives

authors： Fujiki H,Suganuma M,Yoshizawa S,Nishiwaki S,Winyar B,Sugimura T

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Whether there is a causal relation between long-term exposure to traffic and asthma development is so far not clear. This may be explained by inaccurate exposure assessment. OBJECTIVE:We investigated the associations of long-term traffic-related exposures with asthma onset assessed retrospectively and respi...

journal_title：Environmental health perspectives

authors： Oftedal B,Nystad W,Brunekreef B,Nafstad P

更新日期：2009-05-01 00:00:00

abstract：:Potential public health effects associated with exposure to metal emissions from hazardous waste incinerators through noninhalation pathways were evaluated. Instead of relying on modeling the movement of toxicants through various environmental media, an approach based on estimating changes from baseline levels of expo...

journal_title：Environmental health perspectives

authors： Sedman RM,Polisini JM,Esparza JR

更新日期：1994-06-01 00:00:00

abstract：:Stable associations of syntrophic fermentative organisms and populations that consume fermentation products play key roles in the anaerobic biodegradation of chlorinated organic contaminants. The involvement of these syntrophic populations is essential for mineralization of chlorinated aromatic compounds under methano...

journal_title：Environmental health perspectives

authors： Becker JG,Berardesco G,Rittmann BE,Stahl DA

更新日期：2005-03-01 00:00:00

abstract：:We conducted experiments to determine whether diesel engine exhaust affects reproductive endocrine function in growing rats. The rats were assigned to three groups: a group exposed to total diesel engine exhaust containing 5.63 mg/m3 particulate matter, 4.10 ppm nitrogen dioxide, and 8.10 ppm nitrogen oxide; a group e...

journal_title：Environmental health perspectives

authors： Watanabe N,Oonuki Y

更新日期：1999-07-01 00:00:00

abstract：:The lymphocyte micronucleus assay was used to measure the average frequency of micronuclei in a population and thus assess genotoxic effects. Data from 174 persons give an average value of 16.4 +/- 7.3, and a slight age-dependence was observed. To detect combined environmental mutagen injuries the micronucleus assay w...

journal_title：Environmental health perspectives

authors： Bérces J,Otos M,Szirmai S,Crane-Uruena C,Köteles GJ

更新日期：1993-10-01 00:00:00

abstract：:Clinical and experimental studies on respiratory involvement and alterations in immune status were carried out. Respiratory distress occurring in these patients has improved gradually for 14 years but still remains. Copious expectoration at an early stage of the disease may be related to the fact that a number of disc...

journal_title：Environmental health perspectives

authors： Nakanishi Y,Shigematsu N,Kurita Y,Matsuba K,Kanegae H,Ishimaru S,Kawazoe Y

更新日期：1985-02-01 00:00:00