Relation between methylmercury exposure and plasma paraoxonase activity in inuit adults from Nunavik.

abstract：BACKGROUND:Chronic exposure to well water arsenic (As) remains a major rural health challenge in Bangladesh and some other developing countries. Many mitigation programs have been implemented to reduce As exposure, although evaluation studies for these efforts are rare in the literature. OBJECTIVES:In this study we es...

journal_title：Environmental health perspectives

authors： Khan K,Ahmed E,Factor-Litvak P,Liu X,Siddique AB,Wasserman GA,Slavkovich V,Levy D,Mey JL,van Geen A,Graziano JH

更新日期：2015-12-01 00:00:00

abstract：:The presence of blue-green algae (BGA) toxins in surface waters used for drinking water sources and recreation is receiving increasing attention around the world as a public health concern. However, potential risks from exposure to these toxins in contaminated health food products that contain BGA have been largely ig...

journal_title：Environmental health perspectives

authors： Gilroy DJ,Kauffman KW,Hall RA,Huang X,Chu FS

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...

journal_title：Environmental health perspectives

authors： Ljung K,Vahter M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Understanding the potential links between extreme weather events and human health in India is important in the context of vulnerability and adaptation to climate change. Research exploring such linkages in India is sparse. OBJECTIVES:We evaluated the association between extreme precipitation and gastrointes...

journal_title：Environmental health perspectives

authors： Bush KF,O'Neill MS,Li S,Mukherjee B,Hu H,Ghosh S,Balakrishnan K

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The Consortium Linking Academic and Regulatory Insights on Bisphenol-A (CLARITY-BPA) is a rare collaboration of guideline-compliant (core) studies and academic hypothesis-based studies to assess the effects of bisphenol A (BPA). OBJECTIVES:We aimed to a) determine whether BPA showed effects on the developin...

journal_title：Environmental health perspectives

authors： Montévil M,Acevedo N,Schaeberle CM,Bharadwaj M,Fenton SE,Soto AM

更新日期：2020-05-01 00:00:00

abstract：:The role of the physical environment as a determinant of health is a major concern reported by the general public as well as by many policymakers. However, it remains one of the health determinants for which few available measures or indicators are readily available. This lack of data is compounded by the fact that ev...

journal_title：Environmental health perspectives

authors： Elliott SJ,Eyles J,DeLuca P

更新日期：2001-12-01 00:00:00

abstract：:Humans are exposed to a large number of environmental chemicals: Some of these may be toxic, and many others have unknown or poorly characterized health effects. There is intense interest in determining the impact of exposure to environmental chemical mixtures on human health. As the study of mixtures continues to evo...

journal_title：Environmental health perspectives

authors： Braun JM,Gennings C,Hauser R,Webster TF

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Previous studies indicate that the design of streets and sidewalks can influence physical activity among residents. Park features also influence park use and park-based physical activity. Although individuals can walk on streets and sidewalks, walking loops in parks offer a setting to walk in nature and to a...

journal_title：Environmental health perspectives

authors： Cohen DA,Han B,Evenson KR,Nagel C,McKenzie TL,Marsh T,Williamson S,Harnik P

更新日期：2017-02-01 00:00:00

abstract：:Biological monitoring of genotoxic hazard in the rubber industry was performed in 19 male workers and 20 age-matched controls in a local health unit in northern Italy. Peripheral blood lymphocytes were analyzed for the presence of DNA damage (single-cell microgel-electrophoresis, or comet assay) and for cytogenetic pa...

journal_title：Environmental health perspectives

authors： Moretti M,Villarini M,Scassellati-Sforzolini G,Monarca S,Libraro M,Fatigoni C,Donato F,Leonardis C,Perego L

更新日期：1996-05-01 00:00:00

abstract：:Epidemiological studies report a small but positive association between short-term increases in airborne particulate matter and small increases in morbidity and mortality from respiratory and cardiovascular disease in urban areas. However, the lack of a mechanistic explanation to link particle exposure and human healt...

journal_title：Environmental health perspectives

authors： Holian A,Hamilton RF Jr,Morandi MT,Brown SD,Li L

更新日期：1998-03-01 00:00:00

abstract：:The hexavalent oxidation state of chromium [Cr(VI)] is a well-established human carcinogen, although the mechanism of cancer induction is currently unknown. Intracellular reduction of Cr(VI) forms Cr(V), which is thought to play a fundamental role in the mechanism of DNA damage by this carcinogen. Two separate pathway...

journal_title：Environmental health perspectives

authors： Sugden KD,Martin BD

更新日期：2002-10-01 00:00:00

abstract：:The potential impact of an agent altering male reproductive function is greater for humans than for animals. Consequently, it is essential that sensitive criteria be used to look for effects on a multiplicity of target sites when an agent is evaluated using an animal model. No animal model has reproductive characteris...

journal_title：Environmental health perspectives

authors： Amann RP

更新日期：1986-12-01 00:00:00

abstract：:We evaluated the effect of chronic exposure to dioxin and dioxin-like compounds on the pancreas in female Harlan Sprague-Dawley rats. This investigation represents part of an ongoing National Toxicology Program initiative to determine the relative potency of chronic toxicity and carcinogenicity of polychlorinated diox...

journal_title：Environmental health perspectives

authors： Nyska A,Jokinen MP,Brix AE,Sells DM,Wyde ME,Orzech D,Haseman JK,Flake G,Walker NJ

更新日期：2004-06-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants released by the World Trade Center (WTC) fires and various urban combustion sources. Benzo[a]pyrene (BaP) is a representative member of the class of PAHs. PAH-DNA adducts, or BaP-DNA adducts as their proxy, provide a measure of chemical-specific genetic dama...

journal_title：Environmental health perspectives

authors： Perera FP,Tang D,Rauh V,Lester K,Tsai WY,Tu YH,Weiss L,Hoepner L,King J,Del Priore G,Lederman SA

更新日期：2005-08-01 00:00:00

abstract：:The subchronic inhalation toxicology of ethylene glycol monoethyl ether (EGEE) was evaluated in rats and rabbits using a 13-week exposure regimen. Groups of 20 rabbits (10 M, 10 F) and 30 rats (15 M, 15 F) were exposed to a vapor of 25 ppm, 100 ppm, or 400 ppm, 6 hr/day, 5 days/week. The control groups received air on...

journal_title：Environmental health perspectives

authors： Barbee SJ,Terrill JB,DeSousa DJ,Conaway CC

更新日期：1984-08-01 00:00:00

abstract：:A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different init...

journal_title：Environmental health perspectives

authors： Holmberg B

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:The association of DDT (dichlorodiphenyltrichloroethane) with breast cancer is controversial, but animal studies directly linking DDT to risk are lacking. Concerns with DDT reside in its environmental persistence, bioaccumulation in breast adipose tissue, and endocrine-disrupting actions. Whereas most attent...

journal_title：Environmental health perspectives

authors： Johnson NA,Ho A,Cline JM,Hughes CL,Foster WG,Davis VL

更新日期：2012-08-01 00:00:00

abstract：:This article presents discussion of the assessment of the exposure of children to fungi, substances derived from fungi, and the environmental conditions that may lead to exposure. The principles driving investigations of fungal contamination and subsequent exposure are presented as well as guidelines for conducting th...

journal_title：Environmental health perspectives

authors： Dillon HK,Miller JD,Sorenson WG,Douwes J,Jacobs RR

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Particulate matter ≤ 2.5 μm in aerodynamic diameter (PM2.5) has been consistently associated with preterm birth (PTB) to varying degrees, but roles of PM2.5 species have been less studied. OBJECTIVE:We estimated risk differences (RD) of PTB (reported per 106 pregnancies) associated with change in ambient co...

journal_title：Environmental health perspectives

authors： Rappazzo KM,Daniels JL,Messer LC,Poole C,Lobdell DT

更新日期：2015-10-01 00:00:00

abstract：:As part of a large pilot investigation of multimedia exposure to several classes of environmental contaminants, the National Human Exposure Assessment Survey (NHEXAS)-Maryland study, we collected 388 semiquantitative food checklists and duplicate diet solid food samples, analyzed for arsenic, cadmium, chromium, and le...

journal_title：Environmental health perspectives

authors： Ryan PB,Scanlon KA,MacIntosh DL

更新日期：2001-02-01 00:00:00

abstract：:In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extrac...

journal_title：Environmental health perspectives

authors： Arrieta DE,Ontiveros CC,Li WW,Garcia JH,Denison MS,McDonald JD,Burchiel SW,Washburn BS

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Modern toxicology is shifting from an observational to a mechanistic science. As part of this shift, high-throughput toxicity assays are being developed using alternative, nonmammalian species to prioritize chemicals and develop prediction models of human toxicity. METHODS:The nematode Caenorhabditis elegan...

journal_title：Environmental health perspectives

authors： Boyd WA,Smith MV,Co CA,Pirone JR,Rice JR,Shockley KR,Freedman JH

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:There is general concern that persistent organic pollutants (POPs) found in the environment, wildlife, food, water, house dust, human tissues, and fluids may alter normal human physiologic activities (e.g., fetal development, immune and endocrine systems). Although the levels of some POPs [polychlorinated bi...

journal_title：Environmental health perspectives

authors： Doucet J,Tague B,Arnold DL,Cooke GM,Hayward S,Goodyer CG

更新日期：2009-04-01 00:00:00

abstract：:Elucidation of the role of vinyl chloride metabolites in the various reaction sequences which comprise the metabolic pathway, including the interaction of reactive metabolities with some purine and pyrimidine residues of target-organ DNA, provides some explanation for the (oncogenic) properties associated with the ori...

journal_title：Environmental health perspectives

authors： Hathway DE

更新日期：1977-12-01 00:00:00

abstract：:It has been estimated that 4 of 1,000 live births and 35% of spontaneous abortions are aneuploid and that an important proportion of embryo and newborn aneuploidy is of paternal origin. Exposure to organophosphorous pesticides (OP) has been associated with sperm hyperploidy/polyploidy. Therefore, we aimed to assess th...

journal_title：Environmental health perspectives

authors： Recio R,Robbins WA,Borja-Aburto V,Morán-Martínez J,Froines JR,Hernández RM,Cebrián ME

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains undefined. OBJECTIVES:O...

journal_title：Environmental health perspectives

authors： Negro Silva LF,Lemaire M,Lemarié CA,Plourde D,Bolt AM,Chiavatti C,Bohle DS,Slavkovich V,Graziano JH,Lehoux S,Mann KK

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:Perfluoroalkyl acids are persistent compounds used in various industrial -applications. Of these compounds, perfluorooctanoate (PFOA) is currently detected in humans worldwide. A recent study on low-dose developmental exposure to PFOA in mice reported increased weight and elevated biomarkers of adiposity in ...

journal_title：Environmental health perspectives

authors： Halldorsson TI,Rytter D,Haug LS,Bech BH,Danielsen I,Becher G,Henriksen TB,Olsen SF

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess whether the joint effects of three androgen receptor antagonists (vinclozolin, flutamide, procymidone) on male sexual differentiation after in utero and postnatal exposures can be predicted based on dose-response data of the individual chemicals. METHODS:Test chemicals and...

journal_title：Environmental health perspectives

authors： Hass U,Scholze M,Christiansen S,Dalgaard M,Vinggaard AM,Axelstad M,Metzdorff SB,Kortenkamp A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Global climate change is anticipated to reduce future cereal yields and threaten food security, thus potentially increasing the risk of undernutrition. The causation of undernutrition is complex, and there is a need to develop models that better quantify the potential impacts of climate change on population ...

journal_title：Environmental health perspectives

authors： Lloyd SJ,Kovats RS,Chalabi Z

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:We previously conducted a study to assess whether household exposures to tap water increased an individual's internal dose of trihalomethanes (THMs). Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups. OBJECTIVES:Our goal...

journal_title：Environmental health perspectives

authors： Backer LC,Lan Q,Blount BC,Nuckols JR,Branch R,Lyu CW,Kieszak SM,Brinkman MC,Gordon SM,Flanders WD,Romkes M,Cantor KP

更新日期：2008-01-01 00:00:00