Magnetic fields and cancer: animal and cellular evidence--an overview.


:A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different initiators. One study with 2 mT applied on DMBA-initiated mice may suggest a copromotive effect together with the promoter TPA. Another study on rats suggests an inhibitory effect by a magnetic field on rat liver foci formation, induced with DENA. Cell studies show that magnetic fields at some frequencies, amplitudes, and wave forms interact with biological systems. Thus effects have been seen, e.g., on enzymes related to growth regulation, on calcium balance in the cell, on gene expression, and on pineal metabolism and its excretion of the oncostatic melatonin. Cellular and physiologic studies thus suggest effects that may be related to cell multiplication and tumor promotion.


Holmberg B




Has Abstract


1995-03-01 00:00:00








103 Suppl 2


  • Pharmaceuticals and personal care products in the environment: agents of subtle change?

    abstract::During the last three decades, the impact of chemical pollution has focused almost exclusively on the conventional "priority" pollutants, especially those acutely toxic/carcinogenic pesticides and industrial intermediates displaying persistence in the environment. This spectrum of chemicals, however, is only one piece...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Daughton CG,Ternes TA

    更新日期:1999-12-01 00:00:00

  • Exogenous and endogenous determinants of blood trihalomethane levels after showering.

    abstract:BACKGROUND:We previously conducted a study to assess whether household exposures to tap water increased an individual's internal dose of trihalomethanes (THMs). Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups. OBJECTIVES:Our goal...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Backer LC,Lan Q,Blount BC,Nuckols JR,Branch R,Lyu CW,Kieszak SM,Brinkman MC,Gordon SM,Flanders WD,Romkes M,Cantor KP

    更新日期:2008-01-01 00:00:00

  • Mercury in Alaskan Eskimo mothers and infants.

    abstract::The potential danger of natural mercury accumulation in the diet of the Eskimo is evaluated through mercury levels determined in cord blood, placenta, maternal blood, hair, and milk of 38 maternal-infant pairs from Anchorage and the Yukon-Kuskokwim Delta. Although mercury levels are not discernably dangerous, trends t...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Galster WA

    更新日期:1976-06-01 00:00:00

  • State monitoring activities related to Pfiesteria-like organisms.

    abstract::In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland dur...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Magnien RE

    更新日期:2001-10-01 00:00:00

  • Anomalous nonidentity between Salmonella genotoxicants and rodent carcinogens: nongenotoxic carcinogens and genotoxic noncarcinogens.

    abstract::According to current data, the capacity to cause nonprogrammed or unscheduled cell proliferation in target tissues, a common characteristic of chemical carcinogens, may play a more important role in the development of tumors than does genotoxicity. This paper provides strong support for the validity of this conclusion...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Yoshikawa K

    更新日期:1996-01-01 00:00:00

  • Prenatal Exposure to Nonpersistent Endocrine Disruptors and Behavior in Boys at 3 and 5 Years.

    abstract:BACKGROUND:Sex-specific associations have been reported between phthalates, bisphenol A (BPA), and child behavior. No data on large study populations are available for other phenols with possible endocrine-disrupting properties. OBJECTIVES:We aimed to study associations between prenatal exposure to phthalates and seve...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Philippat C,Nakiwala D,Calafat AM,Botton J,De Agostini M,Heude B,Slama R,EDEN Mother–Child Study Group.

    更新日期:2017-09-15 00:00:00

  • Ciguatera fish poisoning and climate change: analysis of National Poison Center Data in the United States, 2001-2011.

    abstract:BACKGROUND:Warm sea surface temperatures (SSTs) are positively related to incidence of ciguatera fish poisoning (CFP). Increased severe storm frequency may create more habitat for ciguatoxic organisms. Although climate change could expand the endemic range of CFP, the relationship between CFP incidence and specific env...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Gingold DB,Strickland MJ,Hess JJ

    更新日期:2014-06-01 00:00:00

  • Chelation of cadmium.

    abstract::The toxicity of cadmium is determined by chelation reactions: in vivo, Cd2+ exists exclusively in coordination complexes with biological ligands, or with administered chelating agents. The Cd2+ ion has some soft character, but it is not a typical soft ion. It has a high degree of polarizability, and its complexes with...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Andersen O

    更新日期:1984-03-01 00:00:00

  • Contribution of lead in dust to children's blood lead.

    abstract::The importance of urban dust as a source of lead for young children is still disputed. Although blood-lead data from various population surveys usually show a peak concentration in early childhood, there is evidence that such a peak is small or absent altogether in children without much access to the general environme...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Duggan MJ

    更新日期:1983-04-01 00:00:00

  • Relationship of aluminum to Alzheimer's disease.

    abstract::Alzheimer's disease is a progressive degenerative brain disease of unknown etiology, characterized by the development of large numbers of neurofibrillary tangles and senile plaques in the brain. Aluminum salts may be used experimentally to produce lesions which are similar, but not identical, to the neurofibrillary ta...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Perl DP

    更新日期:1985-11-01 00:00:00

  • Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents.

    abstract::Of 240 pesticides screened for carcinogenicity by the U.S. Environmental Protection Agency Office of Pesticide Programs, at least 24 (10%) produce thyroid follicular cell tumors in rodents. Thirteen of the thyroid carcinogens also induce liver tumors, mainly in mice, and 9 chemicals produce tumors at other sites. Some...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Hurley PM

    更新日期:1998-08-01 00:00:00

  • Age as a function in the development of sodium-related hypertension.

    abstract::The populations of the developed nations of the world exhibit an increase in blood pressure with age, while in primitive societies blood pressure remains relatively constant throughout adult life. Hypertension may be a complex of diseases all having the same clinical manifestations but not being caused necessarily by ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Tuthill RW,Calabrese EJ

    更新日期:1979-04-01 00:00:00

  • Estimated reduction in cancer risk due to PAH exposures if source control measures during the 2008 Beijing Olympics were sustained.

    abstract:BACKGROUND:The 2008 Beijing Olympic Games provided a unique case study to investigate the effect of source control measures on the reduction in air pollution, and associated inhalation cancer risk, in a Chinese megacity. OBJECTIVES:We measured 17 carcinogenic polycyclic aromatic hydrocarbons (PAHs) and estimated the l...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Jia Y,Stone D,Wang W,Schrlau J,Tao S,Simonich SL

    更新日期:2011-06-01 00:00:00

  • Defining the role of pollutants in the disruption of reproduction in wildlife.

    abstract::Although chemical exposure has been associated with reduced reproduction in certain North American fish, reptiles, and mammals, definitive cause-and-effect data are lacking in many instances. Because the increasing use and global transport of industrial chemicals pose significant risk to successful reproduction, metho...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Hose JE,Guillette LJ

    更新日期:1995-05-01 00:00:00

  • A Web-Based System for Bayesian Benchmark Dose Estimation.

    abstract:BACKGROUND:Benchmark dose (BMD) modeling is an important step in human health risk assessment and is used as the default approach to identify the point of departure for risk assessment. A probabilistic framework for dose-response assessment has been proposed and advocated by various institutions and organizations; ther...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Shao K,Shapiro AJ

    更新日期:2018-01-11 00:00:00

  • Female reproductive function in areas affected by radiation after the Chernobyl power station accident.

    abstract::This paper reports the results of a comprehensive survey of the effects of the accidental release of radiation caused by the accident at the Chernobyl nuclear power station in April 1986. The accident and the resulting release of radiation and radioactive products into the atmosphere produced the most serious environm...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Kulakov VI,Sokur TN,Volobuev AI,Tzibulskaya IS,Malisheva VA,Zikin BI,Ezova LC,Belyaeva LA,Bonartzev PD,Speranskaya NV

    更新日期:1993-07-01 00:00:00

  • The importance of age and smoking in evaluating adverse cytogenetic effects of exposure to environmental agents.

    abstract::Fluorescence in situ hybridization with chromosome-specific composite DNA probes (chromosome painting) is a reliable and efficient method for detecting structural chromosome aberrations. Painting is now being used to quantify chromosome damage in many human populations. In one such study we evaluated 91 unexposed peop...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Tucker JD,Moore DH 2nd

    更新日期:1996-05-01 00:00:00

  • Possibilities of detecting health effects by studies of populations exposed to chemicals from waste disposal sites.

    abstract::Factors affecting the design of an epidemiologic study assessing possible health effects from chemical waste disposal sites are reviewed. Such epidemiologic studies will most likely be prompted either by a known release of chemicals into the environment around the site, or by an unusual disease cluster in a population...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Buffler PA,Crane M,Key MM

    更新日期:1985-10-01 00:00:00

  • Ambient particulate air pollution, heart rate variability, and blood markers of inflammation in a panel of elderly subjects.

    abstract::Epidemiologic studies report associations between particulate air pollution and cardiopulmonary morbidity and mortality. Although the underlying pathophysiologic mechanisms remain unclear, it has been hypothesized that altered autonomic function and pulmonary/systemic inflammation may play a role. In this study we exp...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Pope CA 3rd,Hansen ML,Long RW,Nielsen KR,Eatough NL,Wilson WE,Eatough DJ

    更新日期:2004-03-01 00:00:00

  • Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline.

    abstract::The heterocyclic aromatic amine 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) was evaluated for carcinogenic effects in macaques, primarily cynomolgus monkeys. IQ was administered by gavage five times a week at doses of 10 or 20 mg/kg. IQ induced hepatocellular carcinoma in 55% of the animals at the low dose and in 95%...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Adamson RH,Takayama S,Sugimura T,Thorgeirsson UP

    更新日期:1994-02-01 00:00:00

  • Clues from wildlife to create an assay for thyroid system disruption.

    abstract::In 1996 the U.S. Congress charged the U.S. Environmental Protection Agency to develop a screening program to test chemicals for their possible estrogenic and other endocrine effects. Shortly thereafter, the Chemical Guidelines Program of the Organisation for Economic Co-operation and Development's (OECD) Environmental...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Colborn T

    更新日期:2002-06-01 00:00:00

  • Oxidatively damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes.

    abstract:BACKGROUND:C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event i...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Folkmann JK,Risom L,Jacobsen NR,Wallin H,Loft S,Møller P

    更新日期:2009-05-01 00:00:00

  • Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border.

    abstract::In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extrac...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Arrieta DE,Ontiveros CC,Li WW,Garcia JH,Denison MS,McDonald JD,Burchiel SW,Washburn BS

    更新日期:2003-08-01 00:00:00

  • Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates.

    abstract:BACKGROUND:Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000-2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon. OBJECTIVES:We a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Williams MK,Rundle A,Holmes D,Reyes M,Hoepner LA,Barr DB,Camann DE,Perera FP,Whyatt RM

    更新日期:2008-12-01 00:00:00

  • Lead and cadmium levels and balance and vestibular dysfunction among adult participants in the National Health and Nutrition Examination Survey (NHANES) 1999-2004.

    abstract:BACKGROUND:Few studies have been conducted to identify risk factors for balance and vestibular dysfunction in general populations, but previous studies have reported evidence of adverse effects of lead and cadmium on balance control in high-risk groups. OBJECTIVE:We evaluated the relationship between blood lead and ca...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Min KB,Lee KJ,Park JB,Min JY

    更新日期:2012-03-01 00:00:00

  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells.

    abstract:BACKGROUND:Organophosphate developmental neurotoxicity involves multiple mechanisms converging on neural cell replication and differentiation. OBJECTIVES:We evaluated mechanisms contributing to the adverse effects of chlorpyrifos (CPF) on DNA synthesis, cell number and size, and cell signaling mediated by adenylyl cyc...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Slotkin TA,MacKillop EA,Ryde IT,Seidler FJ

    更新日期:2007-09-01 00:00:00

  • Cord Blood Methylmercury and Fetal Growth Outcomes in Baltimore Newborns: Potential Confounding and Effect Modification by Omega-3 Fatty Acids, Selenium, and Sex.

    abstract:BACKGROUND:Methylmercury (MeHg) may affect fetal growth; however, prior research often lacked assessment of mercury speciation, confounders, and interactions. OBJECTIVE:Our objective was to assess the relationship between MeHg and fetal growth as well as the potential for confounding or interaction of this relationshi...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Wells EM,Herbstman JB,Lin YH,Jarrett J,Verdon CP,Ward C,Caldwell KL,Hibbeln JR,Witter FR,Halden RU,Goldman LR

    更新日期:2016-03-01 00:00:00

  • Thyroid Antagonists (Perchlorate, Thiocyanate, and Nitrate) and Childhood Growth in a Longitudinal Study of U.S. Girls.

    abstract:BACKGROUND:Perchlorate, thiocyanate, and nitrate are sodium/iodide symporter (NIS) inhibitors that block iodide uptake into the thyroid, thus affecting thyroid function. Thyroid dysfunction can adversely affect somatic growth and development in children. To our knowledge, no studies have examined effects of NIS inhibit...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Mervish NA,Pajak A,Teitelbaum SL,Pinney SM,Windham GC,Kushi LH,Biro FM,Valentin-Blasini L,Blount BC,Wolff MS,Breast Cancer and Environment Research Project (BCERP).

    更新日期:2016-04-01 00:00:00

  • Aflatoxin contamination of commercial maize products during an outbreak of acute aflatoxicosis in eastern and central Kenya.

    abstract::In April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths. Aflatoxin-contaminated homegrown maize was the source of the outbreak, but the extent of regional contamination and status of maize in commercial markets (market maize) were unknown. We conducted a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Lewis L,Onsongo M,Njapau H,Schurz-Rogers H,Luber G,Kieszak S,Nyamongo J,Backer L,Dahiye AM,Misore A,DeCock K,Rubin C,Kenya Aflatoxicosis Investigation Group.

    更新日期:2005-12-01 00:00:00

  • Interference of cadmium with ATP-stimulated nuclear calcium uptake.

    abstract::The spatial and temporal regulation of intracellular free Ca2+ serves as a modulator of signal transduction pathways involved in cell growth and differentiation. Thus, interference of metals with intracellular Ca2+ homeostasis has been considered as a target of toxic action. We used the fluorescence indicator fura-2 t...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Hechtenberg S,Beyersmann D

    更新日期:1994-09-01 00:00:00