Increased risk of malignant mesothelioma of the pleura after residential or domestic exposure to asbestos: a case-control study in Casale Monferrato, Italy.

abstract：:We conducted a study on building-related respiratory disease and associated social impact in an office building with water incursions in the northeastern United States. An initial questionnaire had 67% participation (888/1,327). Compared with the U.S. adult population, prevalence ratios were 2.2-2.5 for wheezing, life...

journal_title：Environmental health perspectives

authors： Cox-Ganser JM,White SK,Jones R,Hilsbos K,Storey E,Enright PL,Rao CY,Kreiss K

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Pentachlorophenol, a fungicide widely used as a wood preservative, was classified in 1999 by the International Agency for Research on Cancer as a possible human carcinogen. We reviewed currently available data to determine the extent to which recent studies assist in distinguishing the effect of pentachloroph...

journal_title：Environmental health perspectives

authors： Cooper GS,Jones S

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor targeting estrogen receptors (ERs), has been implicated in the promotion of breast cancer. Perinatal exposure of BPA could induce longitudinal alteration of DNA hydroxymethylation in imprinted loci of mouse blood cells. To date, no data has be...

journal_title：Environmental health perspectives

authors： Li Z,Lyu C,Ren Y,Wang H

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Humans living near industrial point emissions can experience high levels of exposures to air pollutants. Map Ta Phut Industrial Estate in Thailand is the location of the largest steel, oil refinery, and petrochemical factory complexes in Southeast Asia. Air pollution is an important source of oxidative stres...

journal_title：Environmental health perspectives

authors： Peluso M,Srivatanakul P,Munnia A,Jedpiyawongse A,Ceppi M,Sangrajrang S,Piro S,Boffetta P

更新日期：2010-01-01 00:00:00

abstract：:The potential danger of natural mercury accumulation in the diet of the Eskimo is evaluated through mercury levels determined in cord blood, placenta, maternal blood, hair, and milk of 38 maternal-infant pairs from Anchorage and the Yukon-Kuskokwim Delta. Although mercury levels are not discernably dangerous, trends t...

journal_title：Environmental health perspectives

authors： Galster WA

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are flame retardants found in North American household products during the past four decades. These chemicals leach out in dust as products age, exposing individuals daily through inhalation and ingestion. Animal studies suggest that PBDEs disrupt sex hormones and adver...

journal_title：Environmental health perspectives

authors： Goodyer CG,Poon S,Aleksa K,Hou L,Atehortua V,Carnevale A,Koren G,Jednak R,Emil S,Bagli D,Dave S,Hales BF,Chevrier J

更新日期：2017-05-26 00:00:00

abstract：:Gene expression is a unique way of characterizing how cells and organisms adapt to changes in the external environment. The measurements of gene expression levels upon exposure to a chemical can be used both to provide information about the mechanism of action of the toxicant and to form a sort of "genetic signature" ...

journal_title：Environmental health perspectives

authors： Lettieri T

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Maternal factors are implicated in the onset of childhood asthma. Differentiation of naïve CD4+ T lymphocytes into pro-allergic T-helper 2 cells induces interleukin (IL)4 expression and inhibits interferon (IFN)γ expression accompanied by concordant methylation changes in the promoters of these genes. Howeve...

journal_title：Environmental health perspectives

authors： Tang WY,Levin L,Talaska G,Cheung YY,Herbstman J,Tang D,Miller RL,Perera F,Ho SM

更新日期：2012-08-01 00:00:00

abstract：:Rats continuously exposed to NO2 at 0.04, 0.4, and 4.0 ppm for as long as 27 months were submitted to morphological observation and electronmicroscopic morphometry of the lung. At 4 ppm exposure for 9 months, bronchial epithelium showed typical proliferation, which progressed further at 18 months. At this stage, proli...

journal_title：Environmental health perspectives

authors： Kubota K,Murakami M,Takenaka S,Kawai K,Kyono H

更新日期：1987-08-01 00:00:00

abstract：:With this research I tested the hypothesis that individual preferences for specific ecosystem components and restorative environments are significantly associated with quality of life (QOL). A total of 379 human subjects responded to a structured 18-item questionnaire on topophilia and to the 26-item World Health Orga...

journal_title：Environmental health perspectives

authors： Ogunseitan OA

更新日期：2005-02-01 00:00:00

abstract：:A meeting on Marine Biomedical Research, sponsored by the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health and the Smithsonian Institution Museum of Natural History, was attended by approximately 125 scientists, directors and representatives from many of the country's marine b...

journal_title：Environmental health perspectives

authors： Bessey O

更新日期：1976-02-01 00:00:00

abstract：:The metabolism of polybrominated biphenyls (PBBs) was studied in vitro by using rat liver microsomes in the presence of NADPH and atmospheric O2. Quantitative recoveries of all PBBs were obtained after incubations with control or 3-methylcholanthrene (MC) induced microsomes. Of the twelve major components, losses of o...

journal_title：Environmental health perspectives

authors： Dannan GA,Moore RW,Aust SD

更新日期：1978-04-01 00:00:00

abstract：:Embryonal carcinoma (EC) cells offer an interesting model system for evaluating differentiation because the cells are pluripotent, thus resembling germ cells and embryonic stem cells, and because a number of agents have been defined that are capable of promoting the differentiation of these cells. This chapter examine...

journal_title：Environmental health perspectives

authors： Astigiano S,Sherman MI,Abarzúa P

更新日期：1989-03-01 00:00:00

abstract：:The best evidence of an adverse human health effect is a properly conducted epidemiological study. But human beings should not be the sole test animal. Properly conducted animal studies have been shown to be preductive for carcinogenicity and toxicologic responses in human populations. We need to develop more efficien...

journal_title：Environmental health perspectives

authors： Rall DP

更新日期：1979-10-01 00:00:00

abstract：:Determination of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in fly ash and cinders collected from nine municipal incinerators in Japan was made. The concentrations of PCDDs and PCDFs in this study were generally in the same range as those in Europe and North America. However, t...

journal_title：Environmental health perspectives

authors： Wakimoto T,Tatsukawa R

更新日期：1985-02-01 00:00:00

abstract：:This report updates the risk assessment by Crump and Allen for benzene-induced leukemia that was based on a cohort exposed to benzene in the manufacture of Pliofilm. The present study derives new risk estimates using data from follow-up through 1987 (whereas the earlier assessment only had follow-up available through ...

journal_title：Environmental health perspectives

authors： Crump KS

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Lead (Pb) exposure has been associated with a host of pathological conditions in humans. In rodents Pb exposure has been shown to alter the hypothalamic-pituitary-adrenal (HPA) axis function. OBJECTIVE:We investigated the effects of lead on responses of the HPA axis to a psychosocial laboratory stressor adm...

journal_title：Environmental health perspectives

authors： Fortin MC,Cory-Slechta DA,Ohman-Strickland P,Nwankwo C,Yanger TS,Todd AC,Moynihan J,Walton J,Brooks A,Fiedler N

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Aberrant histone acetylation has been observed in carcinogenesis and cellular transformation associated with arsenic exposure; however, the molecular mechanisms and cellular outcomes of such changes are poorly understood. OBJECTIVE:We investigated the impact of tolerated and toxic arsenic trioxide (As2O3) e...

journal_title：Environmental health perspectives

authors： Rahman S,Housein Z,Dabrowska A,Mayán MD,Boobis AR,Hajji N

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Benzene is a common industrial chemical known to induce leukemia and other blood disorders, as well as aneuploidy, in both human blood cells and sperm at exposures > 10 ppm. Recent reports have identified health effects at exposure levels < 1 ppm, the permissible exposure limit (PEL; 8 hr) set by the U.S. Oc...

journal_title：Environmental health perspectives

authors： Xing C,Marchetti F,Li G,Weldon RH,Kurtovich E,Young S,Schmid TE,Zhang L,Rappaport S,Waidyanatha S,Wyrobek AJ,Eskenazi B

更新日期：2010-06-01 00:00:00

abstract：:This paper examines recent risk assessments for benzene and observes a number of inconsistencies within the study and consistencies between studies that should effect the quantitative determination of the risk from benzene exposure. Comparisons across studies show that only acute myeloid leukemia (AML) is found to be ...

journal_title：Environmental health perspectives

authors： Lamm SH,Walters AS,Wilson R,Byrd DM,Grunwald H

更新日期：1989-07-01 00:00:00

abstract：:Sulfur trioxide in the exhaust gas of an internal combustion engine is removed and concentrated by absorption in a solution of 80% isopropyl alcohol, which quantitatively absorbs it and inhibits the oxidation of any sulfur dioxide which may be absorbed. The absorbed sulfur trioxide (sulfuric acid) is determined by an ...

journal_title：Environmental health perspectives

authors： Arnold DR

更新日期：1975-04-01 00:00:00

abstract：:Soil ingestion estimates play an important role in risk assessment of contaminated sites, and estimates of soil ingestion in children are of special interest. Current estimates of soil ingestion are trace-element specific and vary widely among elements. Although expressed as daily estimates, the actual estimates have ...

journal_title：Environmental health perspectives

authors： Stanek EJ 3rd,Calabrese EJ

更新日期：1995-03-01 00:00:00

abstract：:Reaction of chromium(VI) with one equivalent of ascorbate was studied by electron paramagnetic resonance spectroscopy in the presence of 0.10 M 5,5-dimethyl-1-pyrroline-1-oxide (DMPO) at room temperature in 0.10 M (N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid]) (HEPES) and 0.05 M tris(hydroxymethyl)aminometh...

journal_title：Environmental health perspectives

authors： Stearns DM,Courtney KD,Giangrande PH,Phieffer LS,Wetterhahn KE

更新日期：1994-09-01 00:00:00

abstract：:Our desire to understand the potential adverse human health effects of environmental chemical exposure has coincided with an increased understanding of the immune system and an appreciation of its complex regulatory network. This has spawned a broad interest in the area of immunotoxicology within the scientific commun...

journal_title：Environmental health perspectives

authors： Luster MI,Rosenthal GJ

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and endocrine-disrupting chemicals. OBJECTIVES:We used handwipes to estimate exposure to PBDEs in house dust among toddlers and examined sex, age, breast-feeding, race, and parents' education as predictors of serum PBDEs. METHODS:Eight...

journal_title：Environmental health perspectives

authors： Stapleton HM,Eagle S,Sjödin A,Webster TF

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:We reviewed epidemiologic evidence related to occupational pesticide exposures and cancer incidence in the Agricultural Health Study (AHS) cohort. DATA SOURCES:Studies were identified from the AHS publication list available at http://aghealth.nci.nih.gov as well as through a Medline/PubMed database search in...

journal_title：Environmental health perspectives

authors： Weichenthal S,Moase C,Chan P

更新日期：2010-08-01 00:00:00

abstract：:The many anatomical, physiological, and biochemical differences among various mammalian species make it difficult to extrapolate carcinogenic potency data from animals to humans. The process is further complicated by the multistep origin of most malignant tumors in animals and humans due to the interaction of target c...

journal_title：Environmental health perspectives

authors： Slaga TJ

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:We previously conducted a study to assess whether household exposures to tap water increased an individual's internal dose of trihalomethanes (THMs). Increases in blood THM levels among subjects who showered or bathed were variable, with increased levels tending to cluster in two groups. OBJECTIVES:Our goal...

journal_title：Environmental health perspectives

authors： Backer LC,Lan Q,Blount BC,Nuckols JR,Branch R,Lyu CW,Kieszak SM,Brinkman MC,Gordon SM,Flanders WD,Romkes M,Cantor KP

更新日期：2008-01-01 00:00:00

abstract：:A population of approximately 650 beluga (Delphinapterus leucas) inhabits a short segment of the St. Lawrence estuary (SLE). Over 17 years (1983-1999), we have examined 129 (or 49%) of 263 SLE beluga carcasses reported stranded. The major primary causes of death were respiratory and gastrointestinal infections with me...

journal_title：Environmental health perspectives

authors： Martineau D,Lemberger K,Dallaire A,Labelle P,Lipscomb TP,Michel P,Mikaelian I

更新日期：2002-03-01 00:00:00

abstract：:Pavlovian conditioning processes may contribute to some symptoms of multiple chemical sensitivity (MCS). This review summarizes the potential relevance of the literature on conditional taste and olfactory aversions, conditional sensitization, and conditional immunomodulation to understanding MCS. A conditioning-based ...

journal_title：Environmental health perspectives

authors： Siegel S,Kreutzer R

更新日期：1997-03-01 00:00:00