Pentachlorophenol and cancer risk: focusing the lens on specific chlorophenols and contaminants.

abstract：:Proto-oncogenes are cellular genes that are expressed during normal growth and developmental processes. Altered versions of normal proto-oncogenes have been implicated in the development of human neoplasia. In this report, we show the detection of activated proto-oncogenes in various spontaneous and chemically induced...

journal_title：Environmental health perspectives

authors： Stowers SJ,Maronpot RR,Reynolds SH,Anderson MW

更新日期：1987-11-01 00:00:00

abstract：:To assess the possibility that increases in UV-B exposure on the earth's surface could lead to impaired resistance to several infectious diseases, we studied the effect of UV-B exposure on resistance against Trichinella spiralis. Wistar rats, orally infected with T. spiralis larvae, were exposed to suberythemal doses ...

journal_title：Environmental health perspectives

authors： Goettsch W,Garssen J,Deijns A,de Gruijl FR,van Loveren H

更新日期：1994-03-01 00:00:00

abstract：:In the fall of 1976 Congress enacted the Resource Conservation and Recovery Act, commonly referred to as RCRA. The objective of the statute is to create an orderly system for the generation, handling and disposal of hazardous waste by means of a comprehensive tracking and record keeping mechanism. RCRA does not regula...

journal_title：Environmental health perspectives

authors： Friedman M

更新日期：1983-02-01 00:00:00

abstract：:The marriage of toxicology and genomics has created not only opportunities but also novel informatics challenges. As with the larger field of gene expression analysis, toxicogenomics faces the problems of probe annotation and data comparison across different array platforms. Toxicogenomics studies are generally built ...

journal_title：Environmental health perspectives

authors： Mattes WB,Pettit SD,Sansone SA,Bushel PR,Waters MD

更新日期：2004-03-01 00:00:00

abstract：:Relative advantages and disadvantages and important design criteria for various exposure methods are presented. Five types of exposures are discussed: whole-body chambers, head-only exposures, nose or mouth-only methods, lung-only exposures, and partial-lung exposures. Design considerations covered include: air cleani...

journal_title：Environmental health perspectives

authors： Phalen RF

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Biomass smoke is an important source of particulate matter (PM), and much remains to be discovered with respect to the human health effects associated with this specific PM source. Exposure to biomass smoke can occur in one of two main categories: short-term exposures consist of periodic, seasonal exposures ...

journal_title：Environmental health perspectives

authors： Migliaccio CT,Bergauff MA,Palmer CP,Jessop F,Noonan CW,Ward TJ

更新日期：2009-01-01 00:00:00

abstract：:Di(2-ethylhexyl) phthalate (DEHP) is used to make polyvinyl chloride (PVC) plastic tubing soft and flexible. Animal data show that adverse effects of DEHP exposure may include reduced fertility, reduced sperm production in males, and ovarian dysfunction in females. Known treatments that involve high DEHP exposures are...

journal_title：Environmental health perspectives

authors： Rais-Bahrami K,Nunez S,Revenis ME,Luban NL,Short BL

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Although patients with heart failure (HF) have been identified as particularly susceptible to the acute effects of air pollution, the effects of long-term exposure to air pollution on patients with this increasingly prevalent disease are largely unknown. OBJECTIVE:This study was designed to examine the mort...

journal_title：Environmental health perspectives

authors： Medina-Ramón M,Goldberg R,Melly S,Mittleman MA,Schwartz J

更新日期：2008-04-01 00:00:00

abstract：:We report on findings from a 2-year follow-up study of immigrants originating from exposed areas around the site of the 1986 Chernobyl accident matched with comparison subjects emigrating from other republics in the Confederation of Independent States. In the initial study of 708 immigrants, the samples were matched b...

journal_title：Environmental health perspectives

authors： Cwikel J,Abdelgani A,Goldsmith JR,Quastel M,Yevelson II

更新日期：1997-12-01 00:00:00

abstract：:Because of their history of widespread use in the United States and unknown long-term health effects, organophosphate pesticides (OPs) are being considered as a chemical class of interest in planning for the National Children's Study, a longitudinal study of children's environmental health. The availability and approp...

journal_title：Environmental health perspectives

authors： Wessels D,Barr DB,Mendola P

更新日期：2003-12-01 00:00:00

abstract：:As part of a cohort study of the effects of chronic exposure to lead on pregnancy outcome and child development, lead concentrations in the umbilical cord and placental tissues (body and membranes) from 9 late fetal deaths, 23 preterm births, and 18 births associated with premature rupture of the amniotic membranes we...

journal_title：Environmental health perspectives

authors： Baghurst PA,Robertson EF,Oldfield RK,King BM,McMichael AJ,Vimpani GV,Wigg NR

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Chronic exposure to arsenic (As), a human toxicant and carcinogen, remains a global public health problem. Health risks persist after As exposure has ended, suggesting epigenetic dysregulation as a mechanistic link between exposure and health outcomes. OBJECTIVES:We investigated the association between tota...

journal_title：Environmental health perspectives

authors： Bozack AK,Domingo-Relloso A,Haack K,Gamble MV,Tellez-Plaza M,Umans JG,Best LG,Yracheta J,Gribble MO,Cardenas A,Francesconi KA,Goessler W,Tang WY,Fallin MD,Cole SA,Navas-Acien A

更新日期：2020-06-01 00:00:00

abstract：:The additives and contaminants which occur in textile fibers vary widely, depending on the type of fiber and the pretreatment which it has received. Synthetic fibers such as nylon and polyester contain trace amounts of contaminants such as catalysts and catalyst deactivators which remain after the synthesis of the bas...

journal_title：Environmental health perspectives

authors： Barker RH

更新日期：1975-06-01 00:00:00

abstract：:The central feature of hemopoiesis is life-long, stable cell renewal. This process is supported by hemopoietic stem cells which, in the steady state, appear to be dormant in cell cycling. The entry into cell cycle of the dormant stem cells may be promoted by such factors as interleukin-1, interleukin-6 (IL-6), and gra...

journal_title：Environmental health perspectives

authors： Ogawa M

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Industrial air pollution is a public health hazard. Previous evidence documented increased respiratory symptoms and hospitalizations in children who live near the factories in the largest chipboard manufacturing district in Italy (Viadana). OBJECTIVES:We evaluated the association of outdoor exposure to form...

journal_title：Environmental health perspectives

authors： Marcon A,Fracasso ME,Marchetti P,Doria D,Girardi P,Guarda L,Pesce G,Pironi V,Ricci P,de Marco R

更新日期：2014-06-01 00:00:00

abstract：:Implementation of the Toxic Substances Control Act of 1977 creates the need to reliably establish testing priorities because laboratory resources are limited and the number of industrial chemicals requiring evaluation is overwhelming. The use of quantitative structure activity relationship (QSAR) models as rapid and p...

journal_title：Environmental health perspectives

authors： McKim JM,Bradbury SP,Niemi GJ

更新日期：1987-04-01 00:00:00

abstract：:Much public health research has been directed to studies of cancer risks due to chemical agents. Recently, increasing attention has been given to adverse reproductive outcomes as another, shorter-term biologic indicator of public health impact. Further, several low-level ubiquitous physical agents have been implicated...

journal_title：Environmental health perspectives

authors： Meyer RE,Aldrich TE,Easterly CE

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Air pollution data in Bangkok, Thailand, indicate that levels of particulate matter with aerodynamic diameter < or = 10 microm (PM(10)) are significantly higher than in most cities in North America and Western Europe, where the health effects of PM(10) are well documented. However, the pollution mix, seasona...

journal_title：Environmental health perspectives

authors： Vichit-Vadakan N,Vajanapoom N,Ostro B

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Studies suggest that phthalate exposures may adversely affect child respiratory health. OBJECTIVES:We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEH...

journal_title：Environmental health perspectives

authors： Whyatt RM,Perzanowski MS,Just AC,Rundle AG,Donohue KM,Calafat AM,Hoepner LA,Perera FP,Miller RL

更新日期：2014-10-01 00:00:00

abstract：:Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns ...

journal_title：Environmental health perspectives

authors： Landrigan PJ,Suk WA,Amler RW

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Pterygium is a fibrovascular growth of the bulbar conjunctiva and underlying subconjunctival tissue that may cause blindness. The mechanism of pterygium formation is not yet fully understood, but pterygium has some tumorlike features. OBJECTIVES:The objective of this study was to evaluate the association be...

journal_title：Environmental health perspectives

authors： Lin W,Wang SL,Wu HJ,Chang KH,Yeh P,Chen CJ,Guo HR

更新日期：2008-07-01 00:00:00

abstract：:The unique nonrespiratory functions of the lungs have become more apparent in recent years. The isolated perfused lung model offers many advantages over other methods for the study of pulmonary metabolism, xenobiotic disposition and the influence of interactions among agents of different physical forms. Detailed descr...

journal_title：Environmental health perspectives

authors： Niemeier RW

更新日期：1984-06-01 00:00:00

abstract：:Following our first report on elevated polybrominated diphenyl ether (PBDE) concentrations in California women, we expanded our investigation to include diverse groups of local women. We analyzed additional adipose and serum samples collected in the late 1990s from San Francisco Bay Area women participating in a breas...

journal_title：Environmental health perspectives

authors： Petreas M,She J,Brown FR,Winkler J,Windham G,Rogers E,Zhao G,Bhatia R,Charles MJ

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and roxarsone or nitarsone concentrations in poultry meat. However, the association between poultry intake and exposure to these arsenic species, ...

journal_title：Environmental health perspectives

authors： Nigra AE,Nachman KE,Love DC,Grau-Perez M,Navas-Acien A

更新日期：2017-03-01 00:00:00

abstract：:Historical aerial applications of the insecticide Matacil 1.8D provide an opportunity to look for potential effects of the endocrine disrupting compound 4-nonylphenol (4-NP) on Atlantic salmon (Salmo salar) populations. Matacil 1.8D contained the carbamate insecticide aminocarb, with 4-NP as primary solvent. Between 1...

journal_title：Environmental health perspectives

authors： Fairchild WL,Swansburg EO,Arsenault JT,Brown SB

更新日期：1999-05-01 00:00:00

abstract：:Short-term increases in ambient air pollution have been associated with an increased incidence of acute cardiac events. We assessed the effect of inhalation exposure to concentrated ambient particles (CAPs) on myocardial ischemia in a canine model of coronary artery occlusion. Six mongrel dogs underwent thoracotomy fo...

journal_title：Environmental health perspectives

authors： Wellenius GA,Coull BA,Godleski JJ,Koutrakis P,Okabe K,Savage ST,Lawrence JE,Murthy GG,Verrier RL

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Chronic exposure to traffic-related air pollution (TRAP) may contribute to premature mortality, but few studies to date have addressed this topic. OBJECTIVES:In this study we assessed the association between TRAP and mortality in Toronto, Ontario, Canada. METHODS:We collected nitrogen dioxide samples over ...

journal_title：Environmental health perspectives

authors： Jerrett M,Finkelstein MM,Brook JR,Arain MA,Kanaroglou P,Stieb DM,Gilbert NL,Verma D,Finkelstein N,Chapman KR,Sears MR

更新日期：2009-05-01 00:00:00

abstract：:Benzene has been known to be a bone marrow poison for almost a century. However, it was not until the last decade that benzene's carcinogenic potential was demonstrated by epidemiologic studies. The proposed regulation by the Occupational Safety and Health Administration (OSHA) to lower exposure levels of benzene in t...

journal_title：Environmental health perspectives

authors： Infante PF,White MC

更新日期：1983-10-01 00:00:00

abstract：:Cap43 is a protein whose RNA is induced under conditions of severe hypoxia or prolonged elevations of intracellular calcium. Additionally, Ni and Co also induce Cap43 because they produce a state of hypoxia in cells. Cap43 protein is expressed at low levels in normal tissues; however, in a variety of cancers, includin...

journal_title：Environmental health perspectives

authors： Cangul H,Salnikow K,Yee H,Zagzag D,Commes T,Costa M

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Globally, 2.8 billion people rely on household solid fuels. Reducing the resulting adverse health, environmental, and development consequences will involve transitioning through a mix of clean fuels and improved solid fuel stoves (IS) of demonstrable effectiveness. To date, achieving uptake of IS has present...

journal_title：Environmental health perspectives

authors： Rehfuess EA,Puzzolo E,Stanistreet D,Pope D,Bruce NG

更新日期：2014-02-01 00:00:00