Legislative aspects of hazardous waste management.

abstract：:Chromate is an established human carcinogen. There have been many studies of the reactivity of chromate aimed at improving understanding of chromate toxicity. In the present paper a number of conclusions of these studies are reviewed and considered in the light of new results obtained in our laboratories. A number of ...

journal_title：Environmental health perspectives

authors： O'Brien P,Kortenkamp A

更新日期：1994-09-01 00:00:00

abstract：:Studies of DNA base sequence alterations have shown that for every agent the mutagenic process is specific with respect to the types of base changes induced and the location of the changes in the DNA. Analysis of the types of mutations produced by mutagenic agents can provide insight into the mechanism of mutation and...

journal_title：Environmental health perspectives

authors： Skopek TR,Wood RD,Hutchinson F

更新日期：1985-10-01 00:00:00

abstract：:Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies demonstrated that male BD IX rats consuming diets containing 50 ppm fumonisin B1 developed hepatocellular carcinomas. In our recent studies, diets containing FB1 at 50 ...

journal_title：Environmental health perspectives

authors： Howard PC,Warbritton A,Voss KA,Lorentzen RJ,Thurman JD,Kovach RM,Bucci TJ

更新日期：2001-05-01 00:00:00

abstract：:Environmental health and environmental quality issues along the U.S.-Mexico border have been of concern for several years. The enactment of the North American Free Trade Agreement and the presence of the maquiladoras (foreign-owned industries using imported raw materials) have intensified those concerns recently. Effo...

journal_title：Environmental health perspectives

authors： Carter DE,Peña C,Varady R,Suk WA

更新日期：1996-06-01 00:00:00

abstract：:Metal ions form complexes with naturally occurring complexing agents or ligands released from industrial activity. The metal complexes are thereby mobilized and transported in environmental and biological systems. The impact of such metal complexes depends on the metal complex species that are kinetically and thermody...

journal_title：Environmental health perspectives

authors： Fernando Q

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Environmental air pollutants are inhaled as complex mixtures, but the long dominant focus of monitoring and research on individual pollutants has provided modest insight into pollutant interactions that may be important to health. Trends toward managing multiple pollutants to maximize aggregate health gains ...

journal_title：Environmental health perspectives

authors： Mauderly JL,Samet JM

更新日期：2009-01-01 00:00:00

abstract：:32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed occupationally to a mixture of polycyclic aromatic hydrocarbons (PAHs). Preliminary results reported here are from...

journal_title：Environmental health perspectives

authors： Schoket B,Phillips DH,Poirier MC,Vincze I

更新日期：1993-03-01 00:00:00

abstract：:comments on S. Patandin et al. : Dietary exposure to polychlorinated biphenyls and dioxins from infancy until adulthood: a comparison between breast-feeding, toddler, and long-term exposure. Environ Health Perspect 107:45-51 (1999). ...

journal_title：Environmental health perspectives

authors： LaKind JS,Filser JG

更新日期：1999-10-01 00:00:00

abstract：:According to current data, the capacity to cause nonprogrammed or unscheduled cell proliferation in target tissues, a common characteristic of chemical carcinogens, may play a more important role in the development of tumors than does genotoxicity. This paper provides strong support for the validity of this conclusion...

journal_title：Environmental health perspectives

authors： Yoshikawa K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA) is known to be biologically active in experimental models even at low levels of exposure. However, its impact on endometrial cancer remains unclear. OBJECTIVES:This study aimed to investigate whether lifelong exposure to different doses of BPA induced uterine abnormalities and molecular ch...

journal_title：Environmental health perspectives

authors： Leung YK,Biesiada J,Govindarajah V,Ying J,Kendler A,Medvedovic M,Ho SM

更新日期：2020-12-01 00:00:00

abstract：:We evaluated predictors of plasma concentrations of dichlorodiphenyldichloroethylene (DDE), a metabolite of dichlorodiphenyltrichloroethane (DDT), and polychlorinated biphenyls (PCBs) in a group of 240 women, controls from a breast cancer case-control study nested in the Nurses' Health Study. We considered personal at...

journal_title：Environmental health perspectives

authors： Laden F,Neas LM,Spiegelman D,Hankinson SE,Willett WC,Ireland K,Wolff MS,Hunter DJ

更新日期：1999-01-01 00:00:00

abstract：:The chlorinated hydrocarbons chloroform (CHCl3), 1,1-dichlorethane (1,1-DCE) and 1,2-dichloroethane (1,2-DCE) have been detected in finished drinking water. When administered to B6C3F1 mice by gavage in corn oil, these compounds have been shown to induce hepatic tumors. The present study examines the effect on liver t...

journal_title：Environmental health perspectives

authors： Klaunig JE,Ruch RJ,Pereira MA

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Radon is the second-leading cause of lung cancer worldwide. Most indoor exposure occurs by diffusion of soil gas. Radon is also found in well water, natural gas, and ambient air. Pennsylvania has high indoor radon concentrations; buildings are often tested during real estate transactions, with results report...

journal_title：Environmental health perspectives

authors： Casey JA,Ogburn EL,Rasmussen SG,Irving JK,Pollak J,Locke PA,Schwartz BS

更新日期：2015-11-01 00:00:00

abstract：:Embryonal carcinoma (EC) cells offer an interesting model system for evaluating differentiation because the cells are pluripotent, thus resembling germ cells and embryonic stem cells, and because a number of agents have been defined that are capable of promoting the differentiation of these cells. This chapter examine...

journal_title：Environmental health perspectives

authors： Astigiano S,Sherman MI,Abarzúa P

更新日期：1989-03-01 00:00:00

abstract：:Okadaic acid, dinophysistoxin-1 (35-methylokadaic acid), and calyculin A are the okadaic acid class of non-12-O-tetradecanoylphorbol-13-acetate (TPA)-type tumor promoters, which do not bind to the phorbol ester receptors in cell membranes or activate protein kinase C in vitro. They have potent tumor-promoting activiti...

journal_title：Environmental health perspectives

authors： Fujiki H,Suganuma M,Yoshizawa S,Nishiwaki S,Winyar B,Sugimura T

更新日期：1991-06-01 00:00:00

abstract：:Rats were instilled intrabronchially with 1 mg UICC amosite suspended in 0.2 mL of filtered saline; control animals received the saline instillation only. Five animals from each group were killed on various days after instillation, up to day 128/129. Total retrieved cell counts and differential cell analysis were perf...

journal_title：Environmental health perspectives

authors： Oberdoerster G,Ferin J,Marcello NL,Meinhold SH

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Previous literature suggests an association between organochlorines and behavioral measures in childhood, including inattention. OBJECTIVE:This study was designed to assess whether prenatal organochlorine exposure is associated with measures of attention in early infancy. METHODS:We investigated an associa...

journal_title：Environmental health perspectives

authors： Sagiv SK,Nugent JK,Brazelton TB,Choi AL,Tolbert PE,Altshul LM,Korrick SA

更新日期：2008-05-01 00:00:00

abstract：:New technologies and methods for assessing human exposure to chemicals, dietary and lifestyle factors, infectious agents, and other stressors provide an opportunity to extend the range of human health investigations and advance our understanding of the relationship between environmental exposure and disease. An ad hoc...

journal_title：Environmental health perspectives

authors： Weis BK,Balshaw D,Barr JR,Brown D,Ellisman M,Lioy P,Omenn G,Potter JD,Smith MT,Sohn L,Suk WA,Sumner S,Swenberg J,Walt DR,Watkins S,Thompson C,Wilson SH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and...

journal_title：Environmental health perspectives

authors： Malloy TF,Zaunbrecher VM,Batteate CM,Blake A,Carroll WF Jr,Corbett CJ,Hansen SF,Lempert RJ,Linkov I,McFadden R,Moran KD,Olivetti E,Ostrom NK,Romero M,Schoenung JM,Seager TP,Sinsheimer P,Thayer KA

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:Pregnancy is a sensitive condition during which adverse environmental exposures should be monitored thoroughly and minimized whenever possible. In particular, the hormone balance during gestation is delicate, and disturbance may cause acute or chronic long-term health effects. A potential endocrine disruptio...

journal_title：Environmental health perspectives

authors： Warth B,Preindl K,Manser P,Wick P,Marko D,Buerki-Thurnherr T

更新日期：2019-10-01 00:00:00

abstract：:Neurobehavioral toxicology is now established as a core discipline of the environmental health sciences. Despite its recognized scientific prowess, stemming from its deep roots in psychology and neuroscience and its acknowledged successes, it faces additional demands and challenges. The latter, in fact, are a product ...

journal_title：Environmental health perspectives

authors： Weiss B,Elsner J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Differences in the neighborhood food environment may contribute to disparities in obesity. OBJECTIVES:The purpose of this study was to examine the association of neighborhood food environments with body mass index (BMI) and obesity after control for neighborhood walkability. METHODS:This study employed a c...

journal_title：Environmental health perspectives

authors： Rundle A,Neckerman KM,Freeman L,Lovasi GS,Purciel M,Quinn J,Richards C,Sircar N,Weiss C

更新日期：2009-03-01 00:00:00

abstract：:Chlordane is a polychlorinated hydrocarbon that causes liver enlargement and induces mixed-function oxidases similar to those induced by phenobarbitone in the mouse. We have assessed the hepatocarcinogenicity (after 2 years) and the time course (over 6 months) of liver and thyroid cell proliferation in C57Bl/10J mice ...

journal_title：Environmental health perspectives

authors： Barrass N,Stewart M,Warburton S,Aitchison J,Jackson D,Wadsworth P,Marsden A,Orton T

更新日期：1993-12-01 00:00:00

abstract：:To assess quantitatively the association between benzene and leukemia, we evaluated the rate of mortality experienced by a cohort occupationally exposed to benzene. Using data from historical air sampling surveys, we estimated the daily benzene exposure for each member of the cohort. The expected number of leukemia de...

journal_title：Environmental health perspectives

authors： Rinsky RA

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Drinking water contamination related to the use of aqueous film-forming foam (AFFF) has been documented at hundreds of military bases, airports, and firefighter training facilities. AFFF has historically contained high levels of long-chain per- and polyfluoroalkyl substances (PFAS), which pose serious health...

journal_title：Environmental health perspectives

authors： Annunziato KM,Doherty J,Lee J,Clark JM,Liang W,Clark CW,Nguyen M,Roy MA,Timme-Laragy AR

更新日期：2020-09-01 00:00:00

abstract：:In these studies the effects of ingested arsenic (As(+5)) on hepatic heme biosynthetic capability and hemoprotein function in adult male rats were investigated. Animals exposed for 6 weeks to 0, 20, 40, or 85 ppm sodium arsenate in the drinking water suffered depression of hepatic delta-aminolevulinic acid (ALA) synth...

journal_title：Environmental health perspectives

authors： Woods JS,Fowler BA

更新日期：1977-08-01 00:00:00

abstract：:The results of our previous and recent work on cadmium metabolism in relation to age and diet are presented. Experiments were performed on albino rats aged 1-26 weeks. In some experiments rats were given different foods (milk, meat, bread) instead of standard rat diet. Some animals received trisodium calcium salt of d...

journal_title：Environmental health perspectives

authors： Kostial K

更新日期：1984-03-01 00:00:00

abstract：:Cofactors involved in respiratory tract carcinogenesis were studied in Syrian golden hamsters or in rats using benzo(a)pyrene as the carcinogenic agent. These factors included severe tissue damage induced by electro-coagulation, glass fibers administered by intratracheal instillation, acetaldehyde as irritant vapor, f...

journal_title：Environmental health perspectives

authors： Reuzel PG,Feron VJ,Spit BJ,Beems RB,Kroes R

更新日期：1983-04-01 00:00:00

abstract：:Serious problems emerge when evaluating evidence on lead neurotoxicity in children. The extent of these problems and ways to control them were explored in a study of 1291 children from the first class in the schools of Aarhus municipality, Denmark. The lead retention in circumpulpal dentin in shed deciduous teeth was ...

journal_title：Environmental health perspectives

authors： Grandjean P,Lyngbye T,Hansen ON

更新日期：1991-08-01 00:00:00

abstract：:There is widespread concern regarding the safety of silver-mercury amalgam dental restorations, yet little evidence to support their harm or safety. We examined whether mercury dental amalgams are adversely associated with cognitive functioning in a cross-sectional sample of healthy working adults. We studied 550 adul...

journal_title：Environmental health perspectives

authors： Factor-Litvak P,Hasselgren G,Jacobs D,Begg M,Kline J,Geier J,Mervish N,Schoenholtz S,Graziano J

更新日期：2003-05-01 00:00:00