Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variables.

abstract：INTRODUCTION:Prenatal exposure to some pesticides can adversely affect male reproductive health in animals. We investigated a possible human association between maternal exposure to 27 organochlorine compounds used as pesticides and cryptorchidism among male children. DESIGN:Within a prospective birth cohort, we perfo...

journal_title：Environmental health perspectives

authors： Damgaard IN,Skakkebaek NE,Toppari J,Virtanen HE,Shen H,Schramm KW,Petersen JH,Jensen TK,Main KM,Nordic Cryptorchidism Study Group.

更新日期：2006-07-01 00:00:00

abstract：:In April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths. Aflatoxin-contaminated homegrown maize was the source of the outbreak, but the extent of regional contamination and status of maize in commercial markets (market maize) were unknown. We conducted a...

journal_title：Environmental health perspectives

authors： Lewis L,Onsongo M,Njapau H,Schurz-Rogers H,Luber G,Kieszak S,Nyamongo J,Backer L,Dahiye AM,Misore A,DeCock K,Rubin C,Kenya Aflatoxicosis Investigation Group.

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Cockroaches and mice, which are common in urban homes, are sources of allergens capable of triggering asthma symptoms. Traditional pest control involves the use of scheduled applications of pesticides by professionals as well as pesticide use by residents. In contrast, integrated pest management (IPM) involv...

journal_title：Environmental health perspectives

authors： Kass D,McKelvey W,Carlton E,Hernandez M,Chew G,Nagle S,Garfinkel R,Clarke B,Tiven J,Espino C,Evans D

更新日期：2009-08-01 00:00:00

abstract：:We previously reported that cell cultures of human proximal tubule (HPT) cells respond to ionic cadmium in a manner consistent with well-defined Cd(2+)-elicited responses reported for in vivo systems. However, one unique finding was that the transepithelial electrical resistance and tight junction sealing strands were...

journal_title：Environmental health perspectives

authors： Hazen-Martin DJ,Todd JH,Sens MA,Khan W,Bylander JE,Smyth BJ,Sens DA

更新日期：1993-11-01 00:00:00

abstract：:We include in this review an assessment of the formation, environmental fate, and mammalian and ecotoxicity of CW agent degradation products relevant to environmental and occupational health. These parent CW agents include several vesicants: sulfur mustards [undistilled sulfur mustard (H), sulfur mustard (HD), and an ...

journal_title：Environmental health perspectives

authors： Munro NB,Talmage SS,Griffin GD,Waters LC,Watson AP,King JF,Hauschild V

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Organophosphate (OP) pesticides are widely used in agriculture and homes. Animal studies suggest that even moderate doses are neurodevelopmental toxicants, but there are few studies in humans. OBJECTIVES:We investigated the relationship of prenatal and child OP urinary metabolite levels with children's neur...

journal_title：Environmental health perspectives

authors： Eskenazi B,Marks AR,Bradman A,Harley K,Barr DB,Johnson C,Morga N,Jewell NP

更新日期：2007-05-01 00:00:00

abstract：:Reproduction is essential for the continuation of the species and for life itself. In biological terms, living and reproducing are essentially one and the same. There is, therefore, no sharp division between identifying factors harmful to reproduction and identifying factors harmful to life or vice versa. Detection of...

journal_title：Environmental health perspectives

authors： Palmer AK

更新日期：1993-07-01 00:00:00

abstract：:An impressive array of evidence has been obtained during the past decade establishing correlations between specific DNA adducts and carcinogenesis. Many of the studies utilized organ specific differences in carcinogenesis to establish the correlations. More recently, we have investigated similar relationships between ...

journal_title：Environmental health perspectives

authors： Swenberg JA,Richardson FC,Boucheron JA,Dyroff MC

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Rodent models for urban air pollution show consistent induction of inflammatory responses in major brain regions. However, the initial impact of air pollution particulate material on olfactory gateways has not been reported. OBJECTIVE:We evaluated the olfactory neuroepithelium (OE) and brain regional respon...

journal_title：Environmental health perspectives

authors： Cheng H,Saffari A,Sioutas C,Forman HJ,Morgan TE,Finch CE

更新日期：2016-10-01 00:00:00

abstract：:A system suitable for the detection of meiotic aneuploidy is described in which various different origins of the aneuploidy can be distinguished. Aneuploid meiotic products are detected as black disomic spores held in asci containing all the products of a single meiosis. Aneuploidy may result from nondisjunction or fr...

journal_title：Environmental health perspectives

authors： Bond DJ,McMillan L

更新日期：1979-08-01 00:00:00

abstract：:Chemicals may induce cell proliferation directly as mitogens or indirectly via cell death with subsequent proliferation to replace lost cells. Chemically induced proliferation has been demonstrated to play a role in the carcinogenic process. A wide range of procedures and techniques are currently being used to define ...

journal_title：Environmental health perspectives

authors： Goldsworthy TL,Butterworth BE,Maronpot RR

更新日期：1993-12-01 00:00:00

abstract：:In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. In recent years their actual advantages and limitations have been better defined. The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions...

journal_title：Environmental health perspectives

authors： Guillouzo A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Millions of people worldwide consume arsenic-contaminated rice; however, little is known about the uptake and bioavailability of arsenic species after arsenic-contaminated rice ingestion. OBJECTIVES:In this study, we assessed arsenic speciation in greenhouse-grown and supermarket-bought rice, and determined...

journal_title：Environmental health perspectives

authors： Juhasz AL,Smith E,Weber J,Rees M,Rofe A,Kuchel T,Sansom L,Naidu R

更新日期：2006-12-01 00:00:00

abstract：:Methylation is considered the detoxification pathway for inorganic arsenic (InAs), an established human carcinogen. Urinary speciation analysis is used to assess the distribution of metabolites [monomethylarsonate (MMA), dimethylarsinate (DMA), and unmethylated arsenic (InAs)], as indicators of methylation capacity. W...

journal_title：Environmental health perspectives

authors： Hopenhayn-Rich C,Biggs ML,Smith AH,Kalman DA,Moore LE

更新日期：1996-06-01 00:00:00

abstract：:Health is defined as homeostasis of the cellular ecology, and a state where there has not been an inordinate loss, reversible or irreversible, of the structural and/or functional reserves of the body. An adverse health effect is defined as the causation, promotion, facilitation and/or exacerbation of a structural and/...

journal_title：Environmental health perspectives

authors： Sherwin RP

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:In a 1994 Ninth Circuit decision on the remand of Daubert v. Merrell Dow Pharmaceuticals, Inc., Judge Alex Kosinski wrote that science done for the purpose of litigation should be subject to more stringent standards of admissibility than other science. OBJECTIVES:We analyze this proposition by considering l...

journal_title：Environmental health perspectives

authors： Boden LI,Ozonoff D

更新日期：2008-01-01 00:00:00

abstract：:During 1992 and 1993 the Wisconsin Division of Health investigated five cases in which copper-contaminated drinking water was suspected of causing gastrointestinal upsets. Each of these case studies was conducted after our office was notified of high copper levels in drinking water or notified of unexplained illnesses...

journal_title：Environmental health perspectives

authors： Knobeloch L,Ziarnik M,Howard J,Theis B,Farmer D,Anderson H,Proctor M

更新日期：1994-11-01 00:00:00

abstract：:The many anatomical, physiological, and biochemical differences among various mammalian species make it difficult to extrapolate carcinogenic potency data from animals to humans. The process is further complicated by the multistep origin of most malignant tumors in animals and humans due to the interaction of target c...

journal_title：Environmental health perspectives

authors： Slaga TJ

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000-2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon. OBJECTIVES:We a...

journal_title：Environmental health perspectives

authors： Williams MK,Rundle A,Holmes D,Reyes M,Hoepner LA,Barr DB,Camann DE,Perera FP,Whyatt RM

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Although public concern has focused on the environmental impact of the Deepwater Horizon oil spill, the public health impact on a broad range of coastal communities is minimally known. OBJECTIVE:We sought to determine the acute level of distress (depression, anxiety), mechanisms of adjustment (coping, resil...

journal_title：Environmental health perspectives

authors： Grattan LM,Roberts S,Mahan WT Jr,McLaughlin PK,Otwell WS,Morris JG Jr

更新日期：2011-06-01 00:00:00

abstract：:To evaluate the effectiveness of mass screening for uterine cancer in Japan, we compared the changes in the age-adjusted rates of potential years of life lost (PYLL) due to uterine cancer between 1969 and 1972 to 1973 through 1977 between the high coverage-rate (intensively screened) areas and the comparable control a...

journal_title：Environmental health perspectives

authors： Kuroishi T,Hirose K,Tominaga S

更新日期：1990-07-01 00:00:00

abstract：:In this study we examined the impact of weather variability and tides on the transmission of Barmah Forest virus (BFV) disease and developed a weather-based forecasting model for BFV disease in the Gladstone region, Australia. We used seasonal autoregressive integrated moving-average (SARIMA) models to determine the c...

journal_title：Environmental health perspectives

authors： Naish S,Hu W,Nicholls N,Mackenzie JS,McMichael AJ,Dale P,Tong S

更新日期：2006-05-01 00:00:00

abstract：:The 11 September 2001 terrorist attack on New York City's World Trade Center (WTC) caused an unprecedented environmental emergency. The collapse of the towers sent a tremendous cloud of crushed building materials and other pollutants into the air of lower Manhattan. In response to the calamity, federal, state, and cit...

journal_title：Environmental health perspectives

authors： Gavett SH

更新日期：2003-06-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are persistent pollutants that are ubiquitous in the food chain, and detectable amounts are in the blood of almost every person in most populations that have been examined. Extensive evidence from animal studies shows that PCBs are neurotoxins, even at low doses. Interpretation of huma...

journal_title：Environmental health perspectives

authors： Longnecker MP,Wolff MS,Gladen BC,Brock JW,Grandjean P,Jacobson JL,Korrick SA,Rogan WJ,Weisglas-Kuperus N,Hertz-Picciotto I,Ayotte P,Stewart P,Winneke G,Charles MJ,Jacobson SW,Dewailly E,Boersma ER,Altshul LM,Heinzow B

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...

journal_title：Environmental health perspectives

authors： Ljung K,Vahter M

更新日期：2007-11-01 00:00:00

abstract：:Because of their history of widespread use in the United States and unknown long-term health effects, organophosphate pesticides (OPs) are being considered as a chemical class of interest in planning for the National Children's Study, a longitudinal study of children's environmental health. The availability and approp...

journal_title：Environmental health perspectives

authors： Wessels D,Barr DB,Mendola P

更新日期：2003-12-01 00:00:00

abstract：:Soil samples were collected from 28 fields which had received manure from Michigan's most highly contaminated dairy herds. The number of fields in each concentration range of PBB in soil were: 2, not detectable; 15, 0.0 to 8.0 ppb; 6, 14-102 ppb, and 5, 153 to 371 ppb. Plant tissue sampled from the 10 most highly cont...

journal_title：Environmental health perspectives

authors： Jacobs LW,Chou SF,Tiedje JM

更新日期：1978-04-01 00:00:00

abstract：:We present a model of the distribution of noise annoyance with the mean varying as a function of the noise exposure. Day-night level (DNL) and day-evening-night level (DENL) were used as noise descriptors. Because the entire annoyance distribution has been modeled, any annoyance measure that summarizes this distributi...

journal_title：Environmental health perspectives

authors： Miedema HM,Oudshoorn CG

更新日期：2001-04-01 00:00:00

abstract：:We report the results of a coordinated mitigation effort aimed at reducing arsenic (As) exposure in three counties of Guizhou province, China. Mitigation occurred in 2005 and encompassed 21 villages with 47,000 inhabitants, who were exposed to high levels of As in their diet through consumption of As-contaminated chil...

journal_title：Environmental health perspectives

authors： An D,Li D,Liang Y,Jing Z

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event i...

journal_title：Environmental health perspectives

authors： Folkmann JK,Risom L,Jacobsen NR,Wallin H,Loft S,Møller P

更新日期：2009-05-01 00:00:00