Abstract:
:Determination of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in fly ash and cinders collected from nine municipal incinerators in Japan was made. The concentrations of PCDDs and PCDFs in this study were generally in the same range as those in Europe and North America. However, the rather different congener composition compared with those published already were found: higher percentages of lower chlorinated (di- and tri-) dibenzo-p-dioxins and dibenzofurans and no or trace levels of the octachloro compounds, O8CDD and O8CDF. One possible explanation for this difference may be the higher incineration temperature in Japan. The same ranges of concentrations of PCDDs and PCDFs were found in cinders as well as fly ash. The volumes of the cinders are much larger than those of fly ash and therefore the fate and impact of PCDDs and PCDFs in dump sites of these cinders should be studied.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Wakimoto T,Tatsukawa Rdoi
10.1289/ehp.59-1568091subject
Has Abstractpub_date
1985-02-01 00:00:00pages
159-62eissn
0091-6765issn
1552-9924journal_volume
59pub_type
杂志文章abstract::According to current data, the capacity to cause nonprogrammed or unscheduled cell proliferation in target tissues, a common characteristic of chemical carcinogens, may play a more important role in the development of tumors than does genotoxicity. This paper provides strong support for the validity of this conclusion...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.9610440
更新日期:1996-01-01 00:00:00
abstract::Tobacco smoke contains a number of genotoxic compounds that are metabolized to their biologically active forms that subsequently react with cellular DNA to form covalently bound carcinogen-DNA adducts. Several analytical procedures have been developed to detect these adducts in human tissues. Using the nuclease P1-enh...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9399229
更新日期:1993-03-01 00:00:00
abstract::Pesticides used in agriculture may cause adverse health effects among the population living near agricultural areas. However, identifying the populations most likely to be exposed is difficult. We conducted a feasibility study to determine whether satellite imagery could be used to reconstruct historical crop patterns...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.001085
更新日期:2000-01-01 00:00:00
abstract::The phenomenon of fiber-induced cytotoxicity to P388D1 macrophagelike cells has been demonstrated to parallel (thus far without exception) the probability that the fiber will induce a pleural sarcoma (mesothelioma) in rats. This startling parallel in both cases seems to be essentially independent of the chemical natur...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.803491
更新日期:1980-02-01 00:00:00
abstract::Research conducted in recent years has increased public health concern about the toxicity of lead at low dose and has supported a reappraisal of the levels of lead exposure that may be safely tolerated in the workplace. In this article, which appears as part of a mini-monograph on adult lead exposure, we summarize a b...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.9784
更新日期:2007-03-01 00:00:00
abstract::[This corrects the article DOI: 10.1289/EHP2580.]. ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,已发布勘误
doi:10.1289/EHP4002
更新日期:2018-07-05 00:00:00
abstract:BACKGROUND:After several decades of commercial use, the flame-retardant chemicals polybrominated diphenyl ethers (PBDEs) and their metabolites are pervasive environmental contaminants and are detected in the human body. Decabrominated diphenyl ether (decaBDE) is currently the only PBDE in production in the United State...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.11814
更新日期:2009-12-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1307277
更新日期:2014-06-01 00:00:00
abstract::Asbestos and other mineral fibers are carcinogenic to humans and animals but differ from many carcinogens in that they do not induce gene mutations. An understanding of these interesting human carcinogens, therefore, is an important problem in cancer research. Asbestos and other fibers induce predominantly two types o...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.898181
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited. OBJECTIVE:To evaluate whether agricultural chlorpyrifos exposure was associated with mortality, we...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9662
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Prenatal and early-life periods may be critical windows for harmful effects of air pollution on infant health. OBJECTIVES:We studied the association of air pollution exposure during pregnancy and the first year of life with respiratory illnesses, ear infections, and eczema during the first 12-18 months of a...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1205281
更新日期:2013-03-01 00:00:00
abstract::While the rat pancreas is susceptible to experimental cancer induction, the spontaneous incidence of pancreatic cancer in this species is reported to be very low. However, we observed unusually high incidences of focal acinar hyperplasia and acinar adenoma in vehicle control male F344/N rats of some NCI/NTP 2-year tox...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8456213
更新日期:1984-06-01 00:00:00
abstract::To elucidate the effect of intake of mutagenic and/or carcinogenic pyrolysis products of proteins and amino acids on carcinogenesis in man, we have undertaken two epidemiologic cohort studies: one concerning the possible association of broiled fish consumption with cancer and the other concerning the cancer mortality ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8667143
更新日期:1986-08-01 00:00:00
abstract::To analyze the implications for human health, the toxicologist requires four sets of data: the results of toxicity and other studies in animals; quantitative data on actual or potential human exposure; whatever information is available on effects of exposure in man; and the statistical extrapolations from the dose-res...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7932273
更新日期:1979-10-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.00108s1143
更新日期:2000-03-01 00:00:00
abstract::The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to interindividual variations in As metabolism that affect retention and distribution of toxic metabolites. To elucidate the role of genetic factors in As metabolism, we studied how polymorphisms in six genes affected the ...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9734
更新日期:2007-04-01 00:00:00
abstract::Short-term increases in ambient air pollution have been associated with an increased incidence of acute cardiac events. We assessed the effect of inhalation exposure to concentrated ambient particles (CAPs) on myocardial ischemia in a canine model of coronary artery occlusion. Six mongrel dogs underwent thoracotomy fo...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.5775
更新日期:2003-04-01 00:00:00
abstract::Consideration of needs for public health interventions and new research requires comparative assessments of the health benefits that are likely to result from alternative uses of limited regulatory and technical resources. This paper briefly examines regulatory and research priorities in the light of recent informatio...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8141227
更新日期:1981-10-01 00:00:00
abstract::The effect of sodium selenite administered intragastrically in repeated doses to rats receiving ethylmercuric chloride po in various repeated doses (0.25 or 2.5 mg Hg/kg) on the excretion, whole-body retention, and organ distribution of mercury was studied. Selenium was found to affect the distribution of ethylmercury...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.39-1568742
更新日期:1981-06-01 00:00:00
abstract::Acetylcholinesterase (AChE) is the enzyme that hydrolyzes the neurotransmitter acetylcholine at cholinergic synapses and neuromuscular junctions. However, results from our laboratory and others indicate that AChE has an extrasynaptic, noncholinergic role during neural development. This article is a review of our findi...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.99107s181
更新日期:1999-02-01 00:00:00
abstract::The combined effects of carbon monoxide and low temperature on daily variation in hospital admissions for congestive heart failure (CHF) were examined for a 4-year period in Chicago, Illinois. Medicare hospital admissions for CHF were analyzed as a function of the maximum hourly temperature, maximum hourly levels of c...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.98106649
更新日期:1998-10-01 00:00:00
abstract::N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. De...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.834943
更新日期:1983-03-01 00:00:00
abstract::This article provides an overview of methods for reliability assessment of quantitative structure-activity relationship (QSAR) models in the context of regulatory acceptance of human health and environmental QSARs. Useful diagnostic tools and data analytical approaches are highlighted and exemplified. Particular empha...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.5758
更新日期:2003-08-01 00:00:00
abstract::Worldwide climate change and loss of biodiversity are issues of global scope and importance that have recently become subjects of considerable public concern. Unlike classical public health issues and many environmental issues, their perceived threat lies in their potential to disrupt ecological functioning and stabil...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.9196167
更新日期:1991-12-01 00:00:00
abstract:INTRODUCTION:Ambient particulate pollution and traffic have been linked to myocardial infarction and cardiac death risk. Possible mechanisms include autonomic cardiac dysfunction. METHODS:In a repeated-measures study of 46 patients 43-75 years of age, we investigated associations of central-site ambient particulate po...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.0901003
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. OBJECTIVE:We aimed to assess the toxicity of well-characte...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.0800121
更新日期:2009-04-01 00:00:00
abstract::In recent years there has been an increasing focus in environmental risk assessment on children as a potentially susceptible population. There also has been growing recognition of the need for a systematic approach for organizing, evaluating, and incorporating the available data on children's susceptibilities in risk ...
journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.6182
更新日期:2004-02-01 00:00:00
abstract::Direct studies of the function of a given cell type often require that the cell type be obtained in pure culture. A number of different specific metabolic activities have been attributed to pulmonary endothelial cells, yet with few exceptions the conclusions were based on indirect evidence. Thus, to improve our abilit...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8035171
更新日期:1980-04-01 00:00:00
abstract::The identification of certain organic compounds in drinking water has led water treatment specialists to be increasingly concerned about the eventual risks of such pollutants to the health of consumers. Our experiments focused on the role of ozone and granular activated carbon in removing mutagenic compounds and precu...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.8669159
更新日期:1986-11-01 00:00:00
abstract:BACKGROUND:Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000-2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon. OBJECTIVES:We a...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.11367
更新日期:2008-12-01 00:00:00