Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina.

abstract：:We conducted experiments to determine whether diesel engine exhaust affects reproductive endocrine function in growing rats. The rats were assigned to three groups: a group exposed to total diesel engine exhaust containing 5.63 mg/m3 particulate matter, 4.10 ppm nitrogen dioxide, and 8.10 ppm nitrogen oxide; a group e...

journal_title：Environmental health perspectives

authors： Watanabe N,Oonuki Y

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Functional limitations are a major cause for needing care and institutionalization among older adults. Exposure to air pollution has been suggested to be associated with increased functional limitations in older people. OBJECTIVE:Our objective was to assess the association between air pollution and physical...

journal_title：Environmental health perspectives

authors： de Zwart F,Brunekreef B,Timmermans E,Deeg D,Gehring U

更新日期：2018-01-19 00:00:00

abstract：:The significance of the environment for health is increasingly being recognized. There is a need for systematic approaches to assessment of environmental factors most relevant to health, health outcomes most influenced by the environment, and the relationships between them, as well as for approaches to representing th...

journal_title：Environmental health perspectives

authors： Kyle AD,Woodruff TJ,Axelrad DA

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Particulate matter ≤ 2.5 μm in aerodynamic diameter (PM2.5) has been consistently associated with preterm birth (PTB) to varying degrees, but roles of PM2.5 species have been less studied. OBJECTIVE:We estimated risk differences (RD) of PTB (reported per 106 pregnancies) associated with change in ambient co...

journal_title：Environmental health perspectives

authors： Rappazzo KM,Daniels JL,Messer LC,Poole C,Lobdell DT

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

journal_title：Environmental health perspectives

authors： Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

更新日期：2018-04-26 00:00:00

abstract：:The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...

journal_title：Environmental health perspectives

authors：

更新日期：2014-10-30 00:00:00

abstract：:Inhaled asbestos fibers may contribute to three-fourths of malignant mesotheliomas diagnosed in men and almost 40% of cases diagnosed in women. Bans on the manufacture and sale of amphibole asbestos fibers are expected to reduce the incidence of mesothelioma, but the long latency period from initial exposure to clinic...

journal_title：Environmental health perspectives

authors： Tse LA,Yu IT,Goggins W,Clements M,Wang XR,Au JS,Yu KS

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these mechanisms could be important effect modifiers. OBJECTIVE:Our goal was to assess interactions between exposure to air pollution and single nucleotide polymorphisms (S...

journal_title：Environmental health perspectives

authors： Melén E,Nyberg F,Lindgren CM,Berglind N,Zucchelli M,Nordling E,Hallberg J,Svartengren M,Morgenstern R,Kere J,Bellander T,Wickman M,Pershagen G

更新日期：2008-08-01 00:00:00

abstract：:Pesticides used in agriculture may cause adverse health effects among the population living near agricultural areas. However, identifying the populations most likely to be exposed is difficult. We conducted a feasibility study to determine whether satellite imagery could be used to reconstruct historical crop patterns...

journal_title：Environmental health perspectives

authors： Ward MH,Nuckols JR,Weigel SJ,Maxwell SK,Cantor KP,Miller RS

更新日期：2000-01-01 00:00:00

abstract：:Idiopathic Parkinson's disease (IPD) represents a common neurodegenerative disorder. An estimated 2% of the U.S. population, age 65 and older, develops IPD. The number of IPD patients will certainly increase over the next several decades as the baby-boomers gradually step into this high-risk age group, concomitant wit...

journal_title：Environmental health perspectives

authors： Aschner M

更新日期：2000-06-01 00:00:00

abstract：:Calcium has been implicated as a regulatory factor in many physiological and pathophysiological processes in the renal cell. Under physiological conditions, the cytosolic free calcium concentration is maintained at approximately 100 nM. Most of the releasable cell Ca2+ resides in the nonmitochondrial compartments. In ...

journal_title：Environmental health perspectives

authors： Bonventre JV

更新日期：1990-03-01 00:00:00

abstract：:Metals continually rank at the top of the U.S. Environmental Protection Agency's annual list of agents that pose the greatest hazard to the people of the United States. Metals aren't going away, either. They do not biodegrade, and they often concentrate in human and animal cells and tissue. Many metals are known human...

journal_title：Environmental health perspectives

authors： Fisher BE

更新日期：1999-05-01 00:00:00

abstract：:The National Urban Air Toxics Research Center (NUATRC) hosted its first scientific workshop in 1994 that focused on possible relationships between air toxics and asthma. From that meeting came recommendations for future research including a need for more complete individual personal exposure assessments so that determ...

journal_title：Environmental health perspectives

authors： Larsen GL,Beskid C,Shirnamé-Moré L

更新日期：2002-08-01 00:00:00

abstract：:It has been estimated that 4 of 1,000 live births and 35% of spontaneous abortions are aneuploid and that an important proportion of embryo and newborn aneuploidy is of paternal origin. Exposure to organophosphorous pesticides (OP) has been associated with sperm hyperploidy/polyploidy. Therefore, we aimed to assess th...

journal_title：Environmental health perspectives

authors： Recio R,Robbins WA,Borja-Aburto V,Morán-Martínez J,Froines JR,Hernández RM,Cebrián ME

更新日期：2001-12-01 00:00:00

abstract：:A comparative analysis was performed of the phenotype and function of peripheral blood leukocytes of two age-matched cohorts of industrial workers in chemical plants, one of which was exposed occupationally to high concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Median actual TCDD burdens were 116 ng/kg ...

journal_title：Environmental health perspectives

authors： Ernst M,Flesch-Janys D,Morgenstern I,Manz A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) is a known neuro-toxicant. Emerging evidence indicates it may have adverse effects on the neuro-logic and other body systems at common low levels of exposure. Impacts of MeHg exposure could vary by individual susceptibility or be confounded by beneficial nutrients in fish containing MeHg...

journal_title：Environmental health perspectives

authors： Karagas MR,Choi AL,Oken E,Horvat M,Schoeny R,Kamai E,Cowell W,Grandjean P,Korrick S

更新日期：2012-06-01 00:00:00

abstract：:Reproduction is essential for the continuation of the species and for life itself. In biological terms, living and reproducing are essentially one and the same. There is, therefore, no sharp division between identifying factors harmful to reproduction and identifying factors harmful to life or vice versa. Detection of...

journal_title：Environmental health perspectives

authors： Palmer AK

更新日期：1993-07-01 00:00:00

abstract：:1,3-Butadiene is a major monomer in the rubber and plastics industry and is one of the highest-production industrial chemicals in the United States. Although not highly acutely toxic to rodents, inhalation of concentrations as low as 6.25 ppm causes tumors in mice. Butadiene is oncogenic in rats, but much higher expos...

journal_title：Environmental health perspectives

authors： Birnbaum LS

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes. OBJECTIVE:We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of...

journal_title：Environmental health perspectives

authors： Darrow LA,Stein CR,Steenland K

更新日期：2013-10-01 00:00:00

abstract：:The available data on binary interactions are yet to be considered within the context of mixture risk assessment because of our inability to predict the effect of a third or a fourth chemical in the mixture on the interacting binary pairs. Physiologically based pharmacokinetic (PBPK) models represent a potentially use...

journal_title：Environmental health perspectives

authors： Krishnan K,Haddad S,Béliveau M,Tardif R

更新日期：2002-12-01 00:00:00

abstract：:The U.S. Environmental Protection Agency is under a congressional mandate to revise its current standard for arsenic in drinking water. We present a risk assessment for cancers of the bladder, liver, and lung from exposure to arsenic in water, based on data from 42 villages in an arseniasis-endemic region of Taiwan. W...

journal_title：Environmental health perspectives

authors： Morales KH,Ryan L,Kuo TL,Wu MM,Chen CJ

更新日期：2000-07-01 00:00:00

abstract：:The in vivo micronucleus assay can be analyzed by comparing the number of micronuclei (MN) of several dose groups with those of a control group. In several publications, difficulties arose in estimating a suitable distribution for MN, even in the untreated historical control groups. Mitchell et al. described the prese...

journal_title：Environmental health perspectives

authors： Hothorn L

更新日期：1994-01-01 00:00:00

abstract：:The articles in this monograph focus on the mechanisms whereby ambient particulate matter (PM) and co-pollutants deposited in the respiratory tract cause cardiovascular and systemic effects, especially in persons with preexisting conditions such as allergic hyperresponsiveness and pulmonary, cardiac, and vascular dise...

journal_title：Environmental health perspectives

authors： Yeates DB,Mauderly JL

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Pterygium is a fibrovascular growth of the bulbar conjunctiva and underlying subconjunctival tissue that may cause blindness. The mechanism of pterygium formation is not yet fully understood, but pterygium has some tumorlike features. OBJECTIVES:The objective of this study was to evaluate the association be...

journal_title：Environmental health perspectives

authors： Lin W,Wang SL,Wu HJ,Chang KH,Yeh P,Chen CJ,Guo HR

更新日期：2008-07-01 00:00:00

abstract：:Methyl eugenol is a naturally occurring material found in a variety of food sources, including spices, oils, and nutritionally important foods such as bananas and oranges. Given its natural occurrence, a broad cross-section of the population is likely exposed. The availability of biomonitoring and toxicology data offe...

journal_title：Environmental health perspectives

authors： Robison SH,Barr DB

更新日期：2006-11-01 00:00:00

abstract：:The capacity of in vitro bioassays to detect the potential carcinogenicity of metal compounds is reviewed. The in vitro bioassays discussed include: bacterial reversion analysis to determine the capacity of metal salts to revert Salmonella typhimurium histidine auxotrophs or to revert Escherichia coli WP 2 tryp- to tr...

journal_title：Environmental health perspectives

authors： Sirover MA

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:The pesticide atrazine does not bind to or activate the classical estrogen receptor (ER), but it up-regulates the aromatase activity in estrogen-sensitive tumor cells. The G protein estrogen receptor (GPR30/GPER) has been reported to be involved in certain biological responses to endogenous estrogens and env...

journal_title：Environmental health perspectives

authors： Albanito L,Lappano R,Madeo A,Chimento A,Prossnitz ER,Cappello AR,Dolce V,Abonante S,Pezzi V,Maggiolini M

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Phthalates may pose a risk for perinatal developmental effects. An important question relates to the choice of suitable biological matrices for assessing exposure during this period. OBJECTIVES:This study was designed to measure the concentrations of phthalate diesters or their metabolites in breast milk, b...

journal_title：Environmental health perspectives

authors： Högberg J,Hanberg A,Berglund M,Skerfving S,Remberger M,Calafat AM,Filipsson AF,Jansson B,Johansson N,Appelgren M,Håkansson H

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Prenatal and early-life periods may be critical windows for harmful effects of air pollution on infant health. OBJECTIVES:We studied the association of air pollution exposure during pregnancy and the first year of life with respiratory illnesses, ear infections, and eczema during the first 12-18 months of a...

journal_title：Environmental health perspectives

authors： Aguilera I,Pedersen M,Garcia-Esteban R,Ballester F,Basterrechea M,Esplugues A,Fernández-Somoano A,Lertxundi A,Tardón A,Sunyer J

更新日期：2013-03-01 00:00:00

abstract：:In this article we summarize the results of a series of studies that measured the relative bioavailability (RBA) of lead in a variety of soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice a day for 15 days. Blood samples were col...

journal_title：Environmental health perspectives

authors： Casteel SW,Weis CP,Henningsen GM,Brattin WJ

更新日期：2006-08-01 00:00:00