Proliferative lesions of the exocrine pancreas in male F344/N rats.

abstract：BACKGROUND:The biological mechanisms involved in inflammatory response to air pollution are not clearly understood. OBJECTIVE:In this study we assessed the association of short-term air pollutant exposure with inflammatory markers and lung function. METHODS:We studied a cohort of 158 asthmatic and 50 nonasthmatic sch...

journal_title：Environmental health perspectives

authors： Barraza-Villarreal A,Sunyer J,Hernandez-Cadena L,Escamilla-Nuñez MC,Sienra-Monge JJ,Ramírez-Aguilar M,Cortez-Lugo M,Holguin F,Diaz-Sánchez D,Olin AC,Romieu I

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Exposures to high-dose ionizing radiation and high-dose rate ionizing radiation are established risk factors for childhood acute leukemia (AL). The risk of AL following exposure to lower doses due to natural background radiation (NBR) has yet to be conclusively determined. METHODS:AL cases diagnosed over 19...

journal_title：Environmental health perspectives

authors： Demoury C,Marquant F,Ielsch G,Goujon S,Debayle C,Faure L,Coste A,Laurent O,Guillevic J,Laurier D,Hémon D,Clavel J

更新日期：2017-04-01 00:00:00

abstract：:The fundamental problems in population monitoring for genetic effects are twofold: the binomialized nature of the data and the lower power due to small risk of finding positive results. The binomial character is artificial, even forced, and can with advantage be replaced by more refined analysis, and by a focus on all...

journal_title：Environmental health perspectives

authors： Murphy EA

更新日期：1981-12-01 00:00:00

abstract：:The activities of plants and plant/microbial associations may offer a viable means of accomplishing the in situ remediation of contaminated soils. Two uses of plants for phytoremediation are reported here. In one set of studies, the ability of plants to foster degradative microorganisms was investigated. Results indic...

journal_title：Environmental health perspectives

authors： Shann JR

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Human epidemiological and animal studies suggest that developmental exposure to contaminants that activate the aryl hydrocarbon receptor (AHR) lead to suppression of immune system function throughout life. The persistence of immune deficiency throughout life suggests that the cellular target of AHR activatio...

journal_title：Environmental health perspectives

authors： Laiosa MD,Tate ER,Ahrenhoerster LS,Chen Y,Wang D

更新日期：2016-07-01 00:00:00

abstract：:Large quantities of food processing, crop, forestry, and animal solid wastes are generated in the United States each year. The major components of these wastes are biodegradable. However, they also contain components such as nitrogen, human and animal pathogens, medicinals, feed additives, salts, and certain metals, t...

journal_title：Environmental health perspectives

authors： Loehr RC

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. OBJECTIVES:This study was designed to evaluate whether pren...

journal_title：Environmental health perspectives

authors： Xia W,Du X,Zheng T,Zhang B,Li Y,Bassig BA,Zhou A,Wang Y,Xiong C,Li Z,Yao Y,Hu J,Zhou Y,Liu J,Xue W,Ma Y,Pan X,Peng Y,Xu S

更新日期：2016-01-01 00:00:00

abstract：:Collaborative studies were performed to develop a functional assay for fish-killing activity produced by Pfiesteria piscicida. Eight cell lines were used to screen organic fractions and residual water fraction by using a 3-[4, 5-dimethylthiazol-(2-4)]-diphenyltetrazolium bromide cytotoxicity assay. Diethyl ether and a...

journal_title：Environmental health perspectives

authors： Fairey ER,Edmunds JS,Deamer-Melia NJ,Glasgow H Jr,Johnson FM,Moeller PR,Burkholder JM,Ramsdell JS

更新日期：1999-09-01 00:00:00

abstract：:I examined non-Hispanic Black and non-Hispanic White differences in exposure to noncriteria air pollutants in 44 U.S. Census Bureau-defined metropolitan areas with populations greater than one million, using data on air toxics concentrations prepared for the U.S. Environmental Protection Agency as part of its Cumulati...

journal_title：Environmental health perspectives

authors： Lopez R

更新日期：2002-04-01 00:00:00

abstract：:The subchronic inhalation toxicology of ethylene glycol monoethyl ether (EGEE) was evaluated in rats and rabbits using a 13-week exposure regimen. Groups of 20 rabbits (10 M, 10 F) and 30 rats (15 M, 15 F) were exposed to a vapor of 25 ppm, 100 ppm, or 400 ppm, 6 hr/day, 5 days/week. The control groups received air on...

journal_title：Environmental health perspectives

authors： Barbee SJ,Terrill JB,DeSousa DJ,Conaway CC

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Rates of preterm birth have been rising over the past several decades. Factors contributing to this trend remain largely unclear, and exposure to environmental contaminants may play a role. OBJECTIVE:We investigated the relationship between phthalate exposure and preterm birth. METHODS:Within a large Mexic...

journal_title：Environmental health perspectives

authors： Meeker JD,Hu H,Cantonwine DE,Lamadrid-Figueroa H,Calafat AM,Ettinger AS,Hernandez-Avila M,Loch-Caruso R,Téllez-Rojo MM

更新日期：2009-10-01 00:00:00

abstract：:Polychlorinated dibenzo-p-dioxins (PCDDs, dioxins), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are environmental endocrine disruptors that have half-lives of 7-10 years in the human body and have toxicities that probably include carcinogenesis. A high ratio of 4-hydroxyl estradiol (4-O...

journal_title：Environmental health perspectives

authors： Wang SL,Chang YC,Chao HR,Li CM,Li LA,Lin LY,Päpke O

更新日期：2006-05-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) and dioxins are known as neurotoxic compounds that may modulate sex steroid hormones. Steroid hormones play a mediating role in brain development and may influence behaviors that show sex differences, such as childhood play behavior. In this study we evaluated the effects of perinatal ...

journal_title：Environmental health perspectives

authors： Vreugdenhil HJ,Slijper FM,Mulder PG,Weisglas-Kuperus N

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Ambient air ozone (O3) is a pulmonary irritant that has been associated with respiratory health effects including increased lung inflammation and permeability, airway hyperreactivity, respiratory symptoms, and decreased lung function. Estimation of O3 exposure is a complex task because the pollutant exhibits...

journal_title：Environmental health perspectives

authors： Adam-Poupart A,Brand A,Fournier M,Jerrett M,Smargiassi A

更新日期：2014-09-01 00:00:00

abstract：:Granular activated carbon (GAC), in the presence of dilute aqueous hypochlorite solutions typical of those used in water treatment, was converted to a reagent capable of carrying out free-radical coupling reactions and other oxidations of dilute aqueous solutions of phenols. The products included biphenyls with chlori...

journal_title：Environmental health perspectives

authors： Voudrias EA,Larson RA,Snoeyink VL,Chen AS,Stapleton PL

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Organophosphate (OP) pesticides are widely used in agriculture and homes. Animal studies suggest that even moderate doses are neurodevelopmental toxicants, but there are few studies in humans. OBJECTIVES:We investigated the relationship of prenatal and child OP urinary metabolite levels with children's neur...

journal_title：Environmental health perspectives

authors： Eskenazi B,Marks AR,Bradman A,Harley K,Barr DB,Johnson C,Morga N,Jewell NP

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Organophosphate developmental neurotoxicity involves multiple mechanisms converging on neural cell replication and differentiation. OBJECTIVES:We evaluated mechanisms contributing to the adverse effects of chlorpyrifos (CPF) on DNA synthesis, cell number and size, and cell signaling mediated by adenylyl cyc...

journal_title：Environmental health perspectives

authors： Slotkin TA,MacKillop EA,Ryde IT,Seidler FJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Ubiquitous polycyclic aromatic hydrocarbons (PAHs) have been shown to alter gene expression patterns and elevate micronuclei (MN) frequency, but the underlying mechanisms are largely unknown. MicroRNAs (miRNAs) are key gene regulators that may be influenced by PAH exposures and mediate their effects on MN fr...

journal_title：Environmental health perspectives

authors： Deng Q,Huang S,Zhang X,Zhang W,Feng J,Wang T,Hu D,Guan L,Li J,Dai X,Deng H,Zhang X,Wu T

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Cohort studies in North America and western Europe have reported increased risk of mortality associated with long-term exposure to fine particles (PM2.5), but to date, no such studies have been reported in China, where higher levels of exposure are experienced. OBJECTIVES:We estimated the association betwee...

journal_title：Environmental health perspectives

authors： Yin P,Brauer M,Cohen A,Burnett RT,Liu J,Liu Y,Liang R,Wang W,Qi J,Wang L,Zhou M

更新日期：2017-11-07 00:00:00

abstract：:Erythropoietic cells in bone marrow are vulnerable to cytotoxic substances. There are three types of erythroid precursors: cells that can take up Fe but do not proliferate (reticulocytes), those that can take up Fe and proliferate (normoblasts and pronormoblasts), and those cells that do not take up Fe but can prolife...

journal_title：Environmental health perspectives

authors： Lee EW,Kocsis JJ,Snyder R

更新日期：1981-06-01 00:00:00

abstract：:There is accumulating evidence that the multistage carcinogenic process is associated with the progressive acquisition of mutations in cellular proto-oncogenes and in growth-suppressor genes. At the same time, several types of evidence indicate that nongenotoxic agents and epigenetic events also play an important role...

journal_title：Environmental health perspectives

authors： Weinstein IB

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Urbanization has been correlated with hypertension (HTN) in developing countries undergoing rapid economic and environmental transitions. OBJECTIVES:We examined the relationships among living environment (urban, suburban, and rural), day/night land surface temperatures (LST), and blood pressure in selected ...

journal_title：Environmental health perspectives

authors： Estes MG Jr,Al-Hamdan MZ,Crosson W,Estes SM,Quattrochi D,Kent S,McClure LA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Early-life exposure to lead is associated with deficits in neurodevelopment and with hematopoietic system toxicity. DNA methylation may be one of the underlying mechanisms for the adverse effects of prenatal lead on the offspring, but epigenome-wide methylation data for low levels of prenatal lead exposure a...

journal_title：Environmental health perspectives

authors： Wu S,Hivert MF,Cardenas A,Zhong J,Rifas-Shiman SL,Agha G,Colicino E,Just AC,Amarasiriwardena C,Lin X,Litonjua AA,DeMeo DL,Gillman MW,Wright RO,Oken E,Baccarelli AA

更新日期：2017-08-25 00:00:00

abstract：:During the last three decades, the impact of chemical pollution has focused almost exclusively on the conventional "priority" pollutants, especially those acutely toxic/carcinogenic pesticides and industrial intermediates displaying persistence in the environment. This spectrum of chemicals, however, is only one piece...

journal_title：Environmental health perspectives

authors： Daughton CG,Ternes TA

更新日期：1999-12-01 00:00:00

abstract：:This cross-sectional study examined the association between environmental lead measurements surrounding a Los Angeles County battery recycling facility and the blood lead levels of the children living nearby. Environmental lead measurements and blood lead levels of young children living in a community adjacent to a st...

journal_title：Environmental health perspectives

authors： Wohl AR,Dominguez A,Flessel P

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Because of complex interactions of climate variables at the levels of the pathogen, vector, and host, the potential influence of climate change on vector-borne and zoonotic diseases (VBZDs) is poorly understood and difficult to predict. Climate effects on the nonvector-borne zoonotic diseases are especially ...

journal_title：Environmental health perspectives

authors： Mills JN,Gage KL,Khan AS

更新日期：2010-11-01 00:00:00

abstract：:High-dose boric acid (BA) exposure produces testicular lesions in adult rats characterized by inhibited spermiation (IS) that may progress to atrophy. In vivo and in vitro studies addressed possible mechanisms. In vivo, boron tissue disposition was examined, since no detailed data existed, and relevant boron concentra...

journal_title：Environmental health perspectives

authors： Ku WW,Chapin RE

更新日期：1994-11-01 00:00:00

abstract：:The role of lime in the formation of reactive oxygen species (ROS), i.e., O2-., H2O2, and OH., from betel-quid components (extracts of areca nut and catechu) was investigated in vitro using a chemiluminescence technique and an assay for oxidative DNA damage involving analysis of 8-hydroxy-2'-deoxyguanosine. Of the var...

journal_title：Environmental health perspectives

authors： Nair UJ,Obe G,Friesen M,Goldberg MT,Bartsch H

更新日期：1992-11-01 00:00:00

abstract：:The Clean Air Act requires that sensitive subgroups of exposed populations be protected from adverse health effects of air pollution exposure. Hence, data suggesting the existence of sensitive subgroups can have an important impact on regulatory decisions. Some investigators have interpreted differences among individu...

journal_title：Environmental health perspectives

authors： Brunekreef B,Kinney PL,Ware JH,Dockery D,Speizer FE,Spengler JD,Ferris BG Jr

更新日期：1991-01-01 00:00:00

abstract：:Neurobehavioral toxicology is now established as a core discipline of the environmental health sciences. Despite its recognized scientific prowess, stemming from its deep roots in psychology and neuroscience and its acknowledged successes, it faces additional demands and challenges. The latter, in fact, are a product ...

journal_title：Environmental health perspectives

authors： Weiss B,Elsner J

更新日期：1996-04-01 00:00:00