Residential Exposure to Natural Background Radiation and Risk of Childhood Acute Leukemia in France, 1990-2009.

abstract：:A potential connection exists between exposure to organochlorine chemicals and the increasing prevalence of endometriosis. Evidence shows that dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) can increase the incidence and severity of the disease in monkeys and can promote the growth or survival of endometrial tissue impl...

journal_title：Environmental health perspectives

authors： Birnbaum LS,Cummings AM

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Daily adult human exposure to bisphenol A (BPA) has been estimated at <1 µg/kg, with virtually complete first-pass conjugation in the liver in primates but not in mice. We measured unconjugated and conjugated BPA levels in serum from adult female rhesus monkeys and adult female mice after oral administration ...

journal_title：Environmental health perspectives

authors： Taylor JA,Vom Saal FS,Welshons WV,Drury B,Rottinghaus G,Hunt PA,Toutain PL,Laffont CM,VandeVoort CA

更新日期：2011-04-01 00:00:00

abstract：:A series of experiments is described in which operant methodology is used to study the effects of drugs on "learning." Emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state. In this technique, each subject is required to learn a new discriminati...

journal_title：Environmental health perspectives

authors： Thompson DM,Moerschbaecher JM

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Chronic exposure to arsenic (As), a human toxicant and carcinogen, remains a global public health problem. Health risks persist after As exposure has ended, suggesting epigenetic dysregulation as a mechanistic link between exposure and health outcomes. OBJECTIVES:We investigated the association between tota...

journal_title：Environmental health perspectives

authors： Bozack AK,Domingo-Relloso A,Haack K,Gamble MV,Tellez-Plaza M,Umans JG,Best LG,Yracheta J,Gribble MO,Cardenas A,Francesconi KA,Goessler W,Tang WY,Fallin MD,Cole SA,Navas-Acien A

更新日期：2020-06-01 00:00:00

abstract：:This article summarizes the basic facts about the measurement of ionizing radiation, usually referred to as radiation dosimetry. The article defines the common radiation quantities and units; gives typical levels of natural radiation and medical exposures; and describes the most important biological effects of radiati...

journal_title：Environmental health perspectives

authors： Cameron J

更新日期：1991-02-01 00:00:00

abstract：:N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. De...

journal_title：Environmental health perspectives

authors： King CM,Glowinski IB

更新日期：1983-03-01 00:00:00

abstract：:The destruction of the World Trade Center (WTC) on 11 September 2001 in New York City resulted in the massive release of pulverized dust and combustion products. The dust and smoke settled in the surrounding area, which encompassed a large residential community. We hypothesized that previously normal residents in the ...

journal_title：Environmental health perspectives

authors： Reibman J,Lin S,Hwang SA,Gulati M,Bowers JA,Rogers L,Berger KI,Hoerning A,Gomez M,Fitzgerald EF

更新日期：2005-04-01 00:00:00

abstract：:We evaluated the effect of chronic exposure to dioxin and dioxin-like compounds on the pancreas in female Harlan Sprague-Dawley rats. This investigation represents part of an ongoing National Toxicology Program initiative to determine the relative potency of chronic toxicity and carcinogenicity of polychlorinated diox...

journal_title：Environmental health perspectives

authors： Nyska A,Jokinen MP,Brix AE,Sells DM,Wyde ME,Orzech D,Haseman JK,Flake G,Walker NJ

更新日期：2004-06-01 00:00:00

abstract：:Proto-oncogenes are cellular genes that are expressed during normal growth and developmental processes. Altered versions of normal proto-oncogenes have been implicated in the development of human neoplasia. In this report, we show the detection of activated proto-oncogenes in various spontaneous and chemically induced...

journal_title：Environmental health perspectives

authors： Stowers SJ,Maronpot RR,Reynolds SH,Anderson MW

更新日期：1987-11-01 00:00:00

abstract：:Groundwater pollution has become a worrisome phenomenon, mainly for aquifers underlying industrialized areas. In order to evaluate the risk of pollution, a model of the aquifer is needed. Herewith, we describe a quasi-tridimensional model, which we applied to a multilayered aquifer where a phreatic aquifer was coupled...

journal_title：Environmental health perspectives

authors： Ponzini G,Crosta G,Giudici M

更新日期：1989-11-01 00:00:00

abstract：:Studies of DNA base sequence alterations have shown that for every agent the mutagenic process is specific with respect to the types of base changes induced and the location of the changes in the DNA. Analysis of the types of mutations produced by mutagenic agents can provide insight into the mechanism of mutation and...

journal_title：Environmental health perspectives

authors： Skopek TR,Wood RD,Hutchinson F

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Organophosphate flame retardants (PFRs) are becoming popular replacements for the phased-out polybrominated diphenyl ether (PBDE) mixtures, and they are now commonly detected in indoor environments. However, little is known about human exposure to PFRs because they cannot be easily measured in blood or serum...

journal_title：Environmental health perspectives

authors： Hoffman K,Garantziotis S,Birnbaum LS,Stapleton HM

更新日期：2015-02-01 00:00:00

abstract：:Mass poisonings, called yusho and yu-cheng, occurred in western Japan in 1968 and central Taiwan in 1979, respectively. These occurrences were separately caused by ingestion of rice oils contaminated with polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs) and polychlorinated quaterphenyls. The tot...

journal_title：Environmental health perspectives

authors： Masuda Y

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Genetics may partially explain observed heterogeneity in associations between traffic-related air pollution and incident asthma. OBJECTIVE:Our aim was to investigate the impact of gene variants associated with oxidative stress and inflammation on associations between air pollution and incident childhood ast...

journal_title：Environmental health perspectives

authors： MacIntyre EA,Brauer M,Melén E,Bauer CP,Bauer M,Berdel D,Bergström A,Brunekreef B,Chan-Yeung M,Klümper C,Fuertes E,Gehring U,Gref A,Heinrich J,Herbarth O,Kerkhof M,Koppelman GH,Kozyrskyj AL,Pershagen G,Postma DS,Th

更新日期：2014-04-01 00:00:00

abstract：:Studies on the fate of 14C-labeled vinyl chloride (VC) following oral administration and inhalation exposure in rats demonstrated that the disposition of VC in the body is a function of the dose. More importantly, from the data available, it appears that a correlation exists between doses of VC which cause tumors and ...

journal_title：Environmental health perspectives

authors： Watanabe PG,Gehring PJ

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Cadmium exposure may increase the risk of cardiovascular disease. The only published longitudinal study on cadmium and incident cardiovascular disease was performed in American Indians with relatively high cadmium exposure. OBJECTIVES:Our aim was to examine the association between blood cadmium at baseline ...

journal_title：Environmental health perspectives

authors： Barregard L,Sallsten G,Fagerberg B,Borné Y,Persson M,Hedblad B,Engström G

更新日期：2016-05-01 00:00:00

abstract：:Cooking, heat processing, or pyrolysis of protein-rich foods induce the formation of a series of structurally related heterocyclic aromatic bases that have been found to be mutagens. The primary genetic assay utilized to detect and isolate these mutagens has been the his reversion assay in Salmonella typhimurium. The ...

journal_title：Environmental health perspectives

authors： Hatch FT

更新日期：1986-08-01 00:00:00

abstract：:With the "graying of America," the prevalence of neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease (PD) will make increasingly greater demands on Medicare/Medicaid resources, which will greatly strain the national economy. It is imperative that prevention and intervention strategies for t...

journal_title：Environmental health perspectives

authors：

更新日期：1999-07-01 00:00:00

abstract：:Humans are exposed to a large number of environmental genotoxic agents. These can increase the probability that somatic mutation will occur. The use of genotoxicity testing is essential for assessment of potential human toxicity so that hazards can be prevented. Cytogenetic monitoring of human populations exposed to c...

journal_title：Environmental health perspectives

authors： Anwar WA

更新日期：1994-10-01 00:00:00

abstract：:An impressive array of evidence has been obtained during the past decade establishing correlations between specific DNA adducts and carcinogenesis. Many of the studies utilized organ specific differences in carcinogenesis to establish the correlations. More recently, we have investigated similar relationships between ...

journal_title：Environmental health perspectives

authors： Swenberg JA,Richardson FC,Boucheron JA,Dyroff MC

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Ambient air ozone (O3) is a pulmonary irritant that has been associated with respiratory health effects including increased lung inflammation and permeability, airway hyperreactivity, respiratory symptoms, and decreased lung function. Estimation of O3 exposure is a complex task because the pollutant exhibits...

journal_title：Environmental health perspectives

authors： Adam-Poupart A,Brand A,Fournier M,Jerrett M,Smargiassi A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Cockroaches and mice, which are common in urban homes, are sources of allergens capable of triggering asthma symptoms. Traditional pest control involves the use of scheduled applications of pesticides by professionals as well as pesticide use by residents. In contrast, integrated pest management (IPM) involv...

journal_title：Environmental health perspectives

authors： Kass D,McKelvey W,Carlton E,Hernandez M,Chew G,Nagle S,Garfinkel R,Clarke B,Tiven J,Espino C,Evans D

更新日期：2009-08-01 00:00:00

abstract：:A physiologically based pharmacokinetic model for trichloroethylene (TCE) in rodents and humans was calibrated with published toxicokinetic data sets. A Bayesian statistical framework was used to combine previous information about the model parameters with the data likelihood, to yield posterior parameter distribution...

journal_title：Environmental health perspectives

authors： Bois FY

更新日期：2000-05-01 00:00:00

abstract：:The Children's Post-Pesticide Application Exposure Study (CPPAES) was conducted to look at the distribution of chlorpyrifos within a home environment for 2 weeks after a routine professional crack-and-crevice application and to determine the amount of the chlorpyrifos that is absorbed by a child living within the home...

journal_title：Environmental health perspectives

authors： Hore P,Robson M,Freeman N,Zhang J,Wartenberg D,Ozkaynak H,Tulve N,Sheldon L,Needham L,Barr D,Lioy PJ

更新日期：2005-02-01 00:00:00

abstract：:In an earlier study we established that timely and adequate tissue repair response following the administration of a six-fold dose-range of thioacetamide (TA; 50, 150, and 300 mg/kg) prevented progression of injury and led to recovery and animal survival. Delayed and attenuated repair response after the 600 mg/kg TA d...

journal_title：Environmental health perspectives

authors： Mangipudy RS,Rao PS,Mehendale HM

更新日期：1996-07-01 00:00:00

abstract：:All cells contain elaborate systems for the spatial and temporal regulation of the calcium ion, [Ca2+]i, and diverse Ca2+ receptor and biochemical response systems that are regulated by these changes in [Ca2+]i. Toxicants that perturb the mobilization or homeostasis of [Ca2+]i will place the regulation of these proces...

journal_title：Environmental health perspectives

authors： Pounds JG

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:National disparities in asbestos use will likely lead to an unequal burden of asbestos diseases. OBJECTIVES:As economic status may be linked to asbestos use, we assessed, globally, the relationship between indicators of national economic development and asbestos use. METHODS:For the 135 countries that have...

journal_title：Environmental health perspectives

authors： Le GV,Takahashi K,Karjalainen A,Delgermaa V,Hoshuyama T,Miyamura Y,Furuya S,Higashi T,Pan G,Wagner G

更新日期：2010-01-01 00:00:00

abstract：:Because of rampant concern that estrogenic chemicals in the environment may be adversely affecting the health of humans and wildlife, reliable methods for detecting and characterizing estrogenic chemicals are needed. It is important that general agreement be reached on which tests to use and that these tests then be a...

journal_title：Environmental health perspectives

authors： Shelby MD,Newbold RR,Tully DB,Chae K,Davis VL

更新日期：1996-12-01 00:00:00

abstract：:Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (...

journal_title：Environmental health perspectives

authors： Lemmen JG,Arends RJ,van der Saag PT,van der Burg B

更新日期：2004-11-01 00:00:00

abstract：:In 1998, the Helicobacter pylori [(13)C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in t...

journal_title：Environmental health perspectives

authors： Herbarth O,Krumbiegel P,Fritz GJ,Richter M,Schlink U,Müller DM,Richter T

更新日期：2001-06-01 00:00:00