Chlorpyrifos accumulation patterns for child-accessible surfaces and objects and urinary metabolite excretion by children for 2 weeks after crack-and-crevice application.

abstract：:The steroids trenbolone acetate (TbA) and melengestrol acetate (MGA) are licensed as growth promoters for farm animals in several meat-exporting countries. Although many studies have explored their safety for both animals and consumers, little is known about their fate after excretion by the animal. Our study aimed to...

journal_title：Environmental health perspectives

authors： Schiffer B,Daxenberger A,Meyer K,Meyer HH

更新日期：2001-11-01 00:00:00

abstract：:A co-culture clonal survival assay was developed to measure the cytotoxicity of test chemical treatments to BALB/c-3T3 cells because the standard clonal survival assay using 200 wild type (WT) cells frequently overestimates chemical cytotoxicity when compared with identical treatment doses in high-density cultures. Th...

journal_title：Environmental health perspectives

authors： Matthews EJ

更新日期：1993-07-01 00:00:00

abstract：:Biological markers of intermediate health outcomes sometimes provide a superior alternative to traditional measures of pollutant-related disease. Some opportunities and methodologic issues associated with using markers are discussed in the context of exposures to four complex mixtures: environmental tobacco smoke and ...

journal_title：Environmental health perspectives

authors： Wilcosky TC

更新日期：1993-12-01 00:00:00

abstract：:Fluorescence in situ hybridization with chromosome-specific composite DNA probes (chromosome painting) is a reliable and efficient method for detecting structural chromosome aberrations. Painting is now being used to quantify chromosome damage in many human populations. In one such study we evaluated 91 unexposed peop...

journal_title：Environmental health perspectives

authors： Tucker JD,Moore DH 2nd

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The incidence of asbestos-induced human cancers is increasing worldwide, and considerable evidence suggests that reactive oxygen species (ROS) are important mediators of these diseases. Our previous studies suggested that mitochondria might be involved in the initiation of oxidative stress in asbestos-expose...

journal_title：Environmental health perspectives

authors： Huang SX,Partridge MA,Ghandhi SA,Davidson MM,Amundson SA,Hei TK

更新日期：2012-06-01 00:00:00

abstract：:During 1992 and 1993 the Wisconsin Division of Health investigated five cases in which copper-contaminated drinking water was suspected of causing gastrointestinal upsets. Each of these case studies was conducted after our office was notified of high copper levels in drinking water or notified of unexplained illnesses...

journal_title：Environmental health perspectives

authors： Knobeloch L,Ziarnik M,Howard J,Theis B,Farmer D,Anderson H,Proctor M

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The nontherapeutic use of antibiotics in swine feed can select for antibiotic resistance in swine enteric bacteria. Leaking swine waste storage pits and the land-application of swine manure can result in the dispersion of resistant bacteria to water sources. However, there are few data comparing levels of re...

journal_title：Environmental health perspectives

authors： Sapkota AR,Curriero FC,Gibson KE,Schwab KJ

更新日期：2007-07-01 00:00:00

abstract：:Previously, we found that exposure of neonatal rats to chlorpyrifos (CPF) produced brain cell damage and loss, with resultant abnormalities of synaptic development. We used the same biomarkers to examine prenatal CPF treatment so as to define the critical period of vulnerability. One group of pregnant rats received CP...

journal_title：Environmental health perspectives

authors： Qiao D,Seidler FJ,Padilla S,Slotkin TA

更新日期：2002-11-01 00:00:00

abstract：:Lipocortins are structurally related, glucocorticoid-inducible proteins that inhibit phospholipase A2 (PLA2), thereby reducing the liberation of arachidonic acid from phospholipids and so limiting the synthesis of eicosanoid inflammatory mediators. This study is the first demonstration of one lipocortin, lipocortin 1 ...

journal_title：Environmental health perspectives

authors： Smith SF,Tetley TD,Guz A,Flower RJ

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Particulate matter (PM) in outdoor air pollution was recently designated a Group I carcinogen by the International Agency for Research on Cancer (IARC). This determination was based on the evidence regarding the relationship of PM2.5 and PM10 to lung cancer risk; however, the IARC evaluation did not include ...

journal_title：Environmental health perspectives

authors： Hamra GB,Guha N,Cohen A,Laden F,Raaschou-Nielsen O,Samet JM,Vineis P,Forastiere F,Saldiva P,Yorifuji T,Loomis D

更新日期：2014-09-01 00:00:00

abstract：:Dose influences mechanism; and over a wide range of doses, one can envision that mechanism will change with changing dose. This basic concept in toxicology is juxtaposed with the biologic importance of maintaining normal DNA methylation status to provide the focus of this paper. The idea that altered DNA methylation p...

journal_title：Environmental health perspectives

authors： Goodman JI

更新日期：1998-02-01 00:00:00

abstract：:In April 2004, one of the largest aflatoxicosis outbreaks occurred in rural Kenya, resulting in 317 cases and 125 deaths. Aflatoxin-contaminated homegrown maize was the source of the outbreak, but the extent of regional contamination and status of maize in commercial markets (market maize) were unknown. We conducted a...

journal_title：Environmental health perspectives

authors： Lewis L,Onsongo M,Njapau H,Schurz-Rogers H,Luber G,Kieszak S,Nyamongo J,Backer L,Dahiye AM,Misore A,DeCock K,Rubin C,Kenya Aflatoxicosis Investigation Group.

更新日期：2005-12-01 00:00:00

abstract：:In 1998, the Helicobacter pylori [(13)C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in t...

journal_title：Environmental health perspectives

authors： Herbarth O,Krumbiegel P,Fritz GJ,Richter M,Schlink U,Müller DM,Richter T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Several per- and polyfluoroalkyl substances (PFAS) are ubiquitous anthropogenic pollutants almost universally detected in humans. Experimental evidence indicates that PFAS alter glucose metabolism and insulin secretion. However, epidemiological studies have yielded inconsistent results. OBJECTIVE:We sought ...

journal_title：Environmental health perspectives

authors： Cardenas A,Gold DR,Hauser R,Kleinman KP,Hivert MF,Calafat AM,Ye X,Webster TF,Horton ES,Oken E

更新日期：2017-10-02 00:00:00

abstract：:Calcium has been implicated as a regulatory factor in many physiological and pathophysiological processes in the renal cell. Under physiological conditions, the cytosolic free calcium concentration is maintained at approximately 100 nM. Most of the releasable cell Ca2+ resides in the nonmitochondrial compartments. In ...

journal_title：Environmental health perspectives

authors： Bonventre JV

更新日期：1990-03-01 00:00:00

abstract：:The relationship between blood pressure and blood lead was examined in two population samples. One of these consisted of 1137 men aged 49 to 65 years, the other of 865 men and 856 women aged 18 to 64 years. Neither population had any known important exposure to lead, and the 95% ranges of blood lead levels were 6 to 2...

journal_title：Environmental health perspectives

authors： Elwood PC,Davey-Smith G,Oldham PD,Toothill C

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:The mechanisms governing the correlation between exposure to ultrafine particles and the increased incidence of cardiovascular disease remain unknown. Ultrafine particles appear to cross the pulmonary epithelial barrier into the bloodstream, raising the possibility of direct contact with the vascular endothe...

journal_title：Environmental health perspectives

authors： Gojova A,Guo B,Kota RS,Rutledge JC,Kennedy IM,Barakat AI

更新日期：2007-03-01 00:00:00

abstract：:Attention has been focussed, both in man and experimental animals, on the effects of inhalation of the gas monomer, vinyl chloride. Recently, note is being taken of the possible effects of the inhalation of the polymer in man. The particles in question are those produced commercially as paste polymer or dispersion pol...

journal_title：Environmental health perspectives

authors： Wagner JC,Johnson NF

更新日期：1981-10-01 00:00:00

abstract：:Erythropoietic cells in bone marrow are vulnerable to cytotoxic substances. There are three types of erythroid precursors: cells that can take up Fe but do not proliferate (reticulocytes), those that can take up Fe and proliferate (normoblasts and pronormoblasts), and those cells that do not take up Fe but can prolife...

journal_title：Environmental health perspectives

authors： Lee EW,Kocsis JJ,Snyder R

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exhibits neurotoxicity through accumulation in the brain. The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) plays an important role in reducing the cellular accumulation of MeHg. OBJECTIVES:We investigated the protective effect of isothiocyanates, which are kno...

journal_title：Environmental health perspectives

authors： Toyama T,Shinkai Y,Yasutake A,Uchida K,Yamamoto M,Kumagai Y

更新日期：2011-08-01 00:00:00

abstract：:The fundamental problems in population monitoring for genetic effects are twofold: the binomialized nature of the data and the lower power due to small risk of finding positive results. The binomial character is artificial, even forced, and can with advantage be replaced by more refined analysis, and by a focus on all...

journal_title：Environmental health perspectives

authors： Murphy EA

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Microcystin-producing Microcystis bloom is a severe water problem in the world. Some reports indicate that chronic exposure to microcystin may result in liver damage in adults, but information on effects in children is limited. OBJECTIVE:We investigated the relationship between microcystin exposure and live...

journal_title：Environmental health perspectives

authors： Li Y,Chen JA,Zhao Q,Pu C,Qiu Z,Zhang R,Shu W

更新日期：2011-10-01 00:00:00

abstract：:Parental occupational exposures might affect childhood cancer in the offspring through genetic changes in the ovum or sperm or through transplacental carcinogenesis. The 24 published epidemiologic studies of this association have all used case-control designs, with controls generally selected from birth certificates o...

journal_title：Environmental health perspectives

authors： Savitz DA,Chen JH

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Exposure to flame retardants has been associated with negative health outcomes including metabolic effects. As polybrominated diphenyl ether flame retardants were pulled from commerce, human exposure to new flame retardants such as Firemaster® 550 (FM550) has increased. Although previous studies in murine sy...

journal_title：Environmental health perspectives

authors： Tung EWY,Peshdary V,Gagné R,Rowan-Carroll A,Yauk CL,Boudreau A,Atlas E

更新日期：2017-09-14 00:00:00

abstract：BACKGROUND:Psychological sequelae are among the most pronounced effects in populations following exposure to oil spills. Women in particular represent a vulnerable yet influential population but have remained relatively understudied with respect to the Deepwater Horizon oil spill (DHOS). OBJECTIVE:To describe the rela...

journal_title：Environmental health perspectives

authors： Rung AL,Gaston S,Oral E,Robinson WT,Fontham E,Harrington DJ,Trapido E,Peters ES

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Exposure to perfluorooctane sulfonic acid (PFOS) or to perfluorooctanoic acid (PFOA) increases mouse and human peroxisome proliferator-activated receptor alpha (PPARα) subtype activity, which influences lipid metabolism. Because cholesterol is the substrate from which testosterone is synthesized, exposure to...

journal_title：Environmental health perspectives

authors： Maisonet M,Calafat AM,Marcus M,Jaakkola JJ,Lashen H

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Biomass smoke is an important source of particulate matter (PM), and much remains to be discovered with respect to the human health effects associated with this specific PM source. Exposure to biomass smoke can occur in one of two main categories: short-term exposures consist of periodic, seasonal exposures ...

journal_title：Environmental health perspectives

authors： Migliaccio CT,Bergauff MA,Palmer CP,Jessop F,Noonan CW,Ward TJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes. OBJECTIVE:We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of...

journal_title：Environmental health perspectives

authors： Darrow LA,Stein CR,Steenland K

更新日期：2013-10-01 00:00:00

abstract：:32P-Postlabeling analysis and enzyme-linked immunosorbent assay (ELISA) have been used to detect DNA adducts in peripheral blood lymphocytes from primary aluminum production plant workers who were exposed occupationally to a mixture of polycyclic aromatic hydrocarbons (PAHs). Preliminary results reported here are from...

journal_title：Environmental health perspectives

authors： Schoket B,Phillips DH,Poirier MC,Vincze I

更新日期：1993-03-01 00:00:00

abstract：:Diffuse pulmonary fibrosis is associated with bleomycin administration to humans. The sequential reactions of lung cells to this drug have now been investigated in mice following injection of 20 mg/kg bleomycin twice per week for 4 to 8 weeks. Cytoplasmic and subendothelial edema was first observed in large vessels an...

journal_title：Environmental health perspectives

authors： Adamson IY

更新日期：1976-08-01 00:00:00