Two Welsh surveys of blood lead and blood pressure.

abstract：BACKGROUND:Although many studies have examined the effects of air pollution on mortality, data limitations have resulted in fewer studies of both particulate matter with an aerodynamic diameter of 2.5 and < 10 mi...

journal_title：Environmental health perspectives

authors： Zanobetti A,Schwartz J

更新日期：2009-06-01 00:00:00

abstract：:The accumulation of genetic damage in the forms of activated proto-oncogenes and inactivated tumor-suppressor genes is the driving force in the evolution of a normal cell to a malignant cell. For example, both the activation of ras oncogenes and the inactivation of several suppressor genes, including p53, have been ob...

journal_title：Environmental health perspectives

authors： Anderson MW,Reynolds SH,You M,Maronpot RM

更新日期：1992-11-01 00:00:00

abstract：:Aluminum lactate [Al(lact)3] (hydrophilic, hydrolytically unstable) and aluminum acetylacetonate [Al(acae)3] (lipophilic, hydrolytically stable) were tested as potential toxicants to rabbits upon IV administration both as aqueous solutions and as liposome suspensions. Both chemicals behaved as cardiotoxic agents when ...

journal_title：Environmental health perspectives

authors： Bombi GG,Corain B,Favarato M,Giordano R,Nicolini M,Perazzolo M,Tapparo A,Zatta P

更新日期：1990-11-01 00:00:00

abstract：:On 15-16 September 1997, the U.S. Environmental Protection Agency sponsored the Conference on Preventable Causes of Cancer in Children. The conference was convened to examine rising trends in reported incidence of childhood cancer and the association of these trends with environmental exposures. This paper summarizes ...

journal_title：Environmental health perspectives

authors： Carroquino MJ,Galson SK,Licht J,Amler RW,Perera FP,Claxton LD,Landrigan PJ

更新日期：1998-06-01 00:00:00

abstract：:Gene expression is a unique way of characterizing how cells and organisms adapt to changes in the external environment. The measurements of gene expression levels upon exposure to a chemical can be used both to provide information about the mechanism of action of the toxicant and to form a sort of "genetic signature" ...

journal_title：Environmental health perspectives

authors： Lettieri T

更新日期：2006-01-01 00:00:00

abstract：:Chronic exposure to oxidants is associated with an increased incidence of malignancy; however, the mechanism(s) by which oxidants contribute to carcinogenesis is unknown. Since oncogene activation plays an important role in carcinogenesis, we hypothesized that hydroxyl radical-induced DNA damage might contribute to ca...

journal_title：Environmental health perspectives

authors： Jackson JH

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and endocrine-disrupting chemicals. OBJECTIVES:We used handwipes to estimate exposure to PBDEs in house dust among toddlers and examined sex, age, breast-feeding, race, and parents' education as predictors of serum PBDEs. METHODS:Eight...

journal_title：Environmental health perspectives

authors： Stapleton HM,Eagle S,Sjödin A,Webster TF

更新日期：2012-07-01 00:00:00

abstract：:The association of blood lead (B-Pb) concentration to blood pressure was investigated in men aged 55 to 75 years living in the Rome area, who had no history of exposure to lead in the workplace and who participated between 1989 and 1990 in an epidemiologic survey for coronary heart disease (New Risk Factor Project). O...

journal_title：Environmental health perspectives

authors： Menditto A,Morisi G,Spagnolo A,Menotti A

更新日期：1994-11-01 00:00:00

abstract：:A biodosimetric approach to determine alpha-particle dose to the respiratory tract epithelium from known exposures to radon has been developed in the rat. Cytotoxicity assays have been used to obtain dose-conversion factors for cumulative exposures typical of those encountered by underground uranium miners. However, t...

journal_title：Environmental health perspectives

authors： Johnson NF,Carpenter TR,Jaramillo RJ,Liberati TA

更新日期：1997-06-01 00:00:00

abstract：:Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1...

journal_title：Environmental health perspectives

authors： Meeker JD,Ryan L,Barr DB,Herrick RF,Bennett DH,Bravo R,Hauser R

更新日期：2004-12-01 00:00:00

abstract：:The carcinogenic properties of selected metals and their compounds are reviewed to provide a useful reference for existing knowledge on relationships between physical and chemical forms, kinetics and carcinogenic potential and between epidemiology, bioassays, and short-term tests. Extensive consideration is given to a...

journal_title：Environmental health perspectives

authors： Magos L

更新日期：1991-11-01 00:00:00

abstract：:The disruption of the reproductive system of male and female animals in the wild has been attributed to environmental chemicals (xenobiotics). The effects seen mirror alterations one might anticipate if the steroid hormone-dependent processes that regulate these systems were impaired. To determine whether xenobiotics ...

journal_title：Environmental health perspectives

authors： Danzo BJ

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:We have previously shown that adult male mice exposure to low doses of an ubiquitous endocrine disruptor, di(2-ethylhexyl) phthalate (DEHP), alters courtship behavior. OBJECTIVE:The effects of adult exposure to low doses of DEHP alone or in an environmental phthalate mixture on estrous cyclicity, reproducti...

journal_title：Environmental health perspectives

authors： Adam N,Brusamonti L,Mhaouty-Kodja S

更新日期：2021-01-01 00:00:00

abstract：:An increased gastrointestinal cancer risk is associated with occupational exposure to asbestos fiber. Examination of tissues obtained from extrapulmonary organs of exposed workmen demonstrates the presence of asbestos fibers and bodies. The amount of fiber present in these tissues is many magnitudes less than encounte...

journal_title：Environmental health perspectives

authors： Langer AM

更新日期：1974-12-01 00:00:00

abstract：:New technologies and methods for assessing human exposure to chemicals, dietary and lifestyle factors, infectious agents, and other stressors provide an opportunity to extend the range of human health investigations and advance our understanding of the relationship between environmental exposure and disease. An ad hoc...

journal_title：Environmental health perspectives

authors： Weis BK,Balshaw D,Barr JR,Brown D,Ellisman M,Lioy P,Omenn G,Potter JD,Smith MT,Sohn L,Suk WA,Sumner S,Swenberg J,Walt DR,Watkins S,Thompson C,Wilson SH

更新日期：2005-07-01 00:00:00

abstract：:The natural occurrence of palladium (Pd) is rare. It is obtained as a by-product during the extraction of platinum and, until the present time, its uses were small in number--principally in the manufacture of jewelry, dental alloys, chemical catalysts, and electrical contacts. Interest in Pd toxicology has been limite...

journal_title：Environmental health perspectives

authors： Wiester MJ

更新日期：1975-12-01 00:00:00

abstract：:The major aspects that must be considered in studies of the health effects of environmental pollutants are: the direct damage due to the exposure, the role of pre-existing disease, and effects of the exposure on the response to secondary stresses. In experimental studies at concentrations of air pollutants found in ur...

journal_title：Environmental health perspectives

authors： Ehrlich R

更新日期：1980-04-01 00:00:00

abstract：:Atlantic coast estuaries recently have experienced fish kills and fish with lesions attributed to Pfiesteria piscicida and related dinoflagellates. Human health effects have been reported from laboratory exposure and from a 1997 Maryland fish kill. North Carolina has recorded Pfiesteria-related fish kill events over t...

journal_title：Environmental health perspectives

authors： Swinker M,Koltai D,Wilkins J,Hudnell K,Hall C,Darcey D,Robertson K,Schmechel D,Stopford W,Music S

更新日期：2001-01-01 00:00:00

abstract：:This cross-sectional study examined the association between environmental lead measurements surrounding a Los Angeles County battery recycling facility and the blood lead levels of the children living nearby. Environmental lead measurements and blood lead levels of young children living in a community adjacent to a st...

journal_title：Environmental health perspectives

authors： Wohl AR,Dominguez A,Flessel P

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and...

journal_title：Environmental health perspectives

authors： Malloy TF,Zaunbrecher VM,Batteate CM,Blake A,Carroll WF Jr,Corbett CJ,Hansen SF,Lempert RJ,Linkov I,McFadden R,Moran KD,Olivetti E,Ostrom NK,Romero M,Schoenung JM,Seager TP,Sinsheimer P,Thayer KA

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:Rodent models for urban air pollution show consistent induction of inflammatory responses in major brain regions. However, the initial impact of air pollution particulate material on olfactory gateways has not been reported. OBJECTIVE:We evaluated the olfactory neuroepithelium (OE) and brain regional respon...

journal_title：Environmental health perspectives

authors： Cheng H,Saffari A,Sioutas C,Forman HJ,Morgan TE,Finch CE

更新日期：2016-10-01 00:00:00

abstract：:The physiological function of copper(I)-metallothionein is not well understood. The respiratory function of hemocyanin, a copper(I)-containing respiratory protein found in the hemolymph of many invertebrates, has been known a long time. However, the mechanism by which Cu(I) is inserted into the oxygen-binding site of ...

journal_title：Environmental health perspectives

authors： Brouwer M,Whaling P,Engel DW

更新日期：1986-03-01 00:00:00

abstract：:The carcinogenic activities of sodium chlorite in B6C3F1 mice were examined. Sodium chlorite was given at concentrations of 0 (control), 0.025% (low dose), or 0.05% (high dose) in the drinking water of 150 female and 150 male mice for 80 weeks, after which time the animals were returned to distilled water without sodi...

journal_title：Environmental health perspectives

authors： Yokose Y,Uchida K,Nakae D,Shiraiwa K,Yamamoto K,Konishi Y

更新日期：1987-12-01 00:00:00

abstract：:This study was undertaken to explore the effects of chronic low-level cadmium ingestion in Dahl hypertension-resistant (R) and hypertension-sensitive (S) lines of rats. Groups of weanling female R and S rats were given 0 or 1 mg cadmium/1. in drinking water and fed either a low salt (0.4% NaCl) or a high salt (4% NaCl...

journal_title：Environmental health perspectives

authors： Ohanian EV,Iwai J

更新日期：1979-02-01 00:00:00

abstract：:The ability of questionnaires to predict children's exposure to pesticides was examined as part of the Minnesota Children's Pesticide Exposure Study (MNCPES). The MNCPES focused on a probability sample of 102 children between the ages of 3 and 13 years living in either urban (Minneapolis and St. Paul, MN) or nonurban ...

journal_title：Environmental health perspectives

authors： Sexton K,Adgate JL,Eberly LE,Clayton CA,Whitmore RW,Pellizzari ED,Lioy PJ,Quackenboss JJ

更新日期：2003-01-01 00:00:00

abstract：:There are still many uncertainties regarding the risk of adverse pregnancy outcomes associated with exposure to drinking water disinfection by-products. In Montréal, Québec, Canada, we carried out a hospital-based case-control study including 493 cases of intrauterine growth restriction defined as birth weight below t...

journal_title：Environmental health perspectives

authors： Infante-Rivard C

更新日期：2004-08-01 00:00:00

abstract：:Exposure to aflatoxin B1 (AFB1), an important cofactor in the etiology of hepatocellular carcinoma in Taiwan, is influenced by dietary and other factors. The present study examined the intraindividual variability in AFB1-albumin adducts, the most reliable long-term biomarker of AFB1 exposure, and whether the baseline ...

journal_title：Environmental health perspectives

authors： Ahsan H,Wang LY,Chen CJ,Tsai WY,Santella RM

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Drinking water in multiple water districts in the Mid-Ohio Valley has been contaminated with perfluorooctanoic acid (PFOA), which was released by a nearby DuPont chemical plant. Two highly contaminated water districts began granular activated carbon filtration in 2007. OBJECTIVES:To determine the rate of de...

journal_title：Environmental health perspectives

authors： Bartell SM,Calafat AM,Lyu C,Kato K,Ryan PB,Steenland K

更新日期：2010-02-01 00:00:00

abstract：:Alveolar macrophages were treated with carbon blacks and adsorbates in order to evaluate the biologic effect of adsorbate, adsorbent and adsorbate-adsorbent complexes. Their capacity to phagocytize a subsequent challenge via the Fc-membrane receptor was quantified. Phagocytosis was suppressed in a dose-related manner ...

journal_title：Environmental health perspectives

authors： Jakab GJ,Risby TH,Sehnert SS,Hmieleski RR,Farrington JE

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The biological mechanisms involved in inflammatory response to air pollution are not clearly understood. OBJECTIVE:In this study we assessed the association of short-term air pollutant exposure with inflammatory markers and lung function. METHODS:We studied a cohort of 158 asthmatic and 50 nonasthmatic sch...

journal_title：Environmental health perspectives

authors： Barraza-Villarreal A,Sunyer J,Hernandez-Cadena L,Escamilla-Nuñez MC,Sienra-Monge JJ,Ramírez-Aguilar M,Cortez-Lugo M,Holguin F,Diaz-Sánchez D,Olin AC,Romieu I

更新日期：2008-06-01 00:00:00