Recommendations for medical management of adult lead exposure.

abstract：:The Tradescantia genetic system developed by the late Dr. Arnold H. Sparrow for the study of effects of ionizing radiation is applicable to chemical mutagen detection. Early radiobiological data demonstrated that the stamen hairs were sensitive to as little as 0.25 rad of x-rays and that the number of cells showing a ...

journal_title：Environmental health perspectives

authors： Schairer LA,Van't Hof J,Hayes CG,Burton RM,de Serres FJ

更新日期：1978-12-01 00:00:00

abstract：:The lysosomes of several varieties of cells such as the tubular proximal cell of the kidney and the alveolar macrophage have the ability to concentrate and precipitate several elements inhaled in water-soluble form, usually as phosphate. The mechanism involved is attributed to the high acid phosphatase activity of lys...

journal_title：Environmental health perspectives

authors： Galle P,Berry JP,Galle C

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:We previously demonstrated that among 54 infants in neonatal intensive care units, exposure to polyvinyl chloride plastic medical devices containing the plasticizer di(2-ethylhexyl) phthalate (DEHP) is associated with urinary concentrations of mono(2-ethylhexyl) phthalate (MEHP) , a DEHP metabolite. In this f...

journal_title：Environmental health perspectives

authors： Weuve J,Sánchez BN,Calafat AM,Schettler T,Green RA,Hu H,Hauser R

更新日期：2006-09-01 00:00:00

abstract：:The timing of some key embryological events is given for man, rat, chick, and certain other animals. Such times, however, are approximations, and variations occur among members of the same strain and even among members of the same litter. Some differences in developmental patterns are indicated. ...

journal_title：Environmental health perspectives

authors： Monie IW

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Animal studies suggest that early-life lead exposure influences gene expression and production of proteins associated with Alzheimer's disease (AD). OBJECTIVES:We attempted to assess the relationship between early-life lead exposure and potential biomarkers for AD among young men and women. We also attempte...

journal_title：Environmental health perspectives

authors： Mazumdar M,Xia W,Hofmann O,Gregas M,Ho Sui S,Hide W,Yang T,Needleman HL,Bellinger DC

更新日期：2012-05-01 00:00:00

abstract：:We measured tumor-associated proteins (TAPs) and pollutants in blood, serum, and urine of 200 nonsmoking women 50-65 years of age, residing in the rural municipality of Peer or in Hoboken or Wilrijk, industrial suburbs of Antwerp, Belgium. Persons with occupational exposures or commuting to other towns were excluded. ...

journal_title：Environmental health perspectives

authors： van Larebeke NA,Bracke ME,Nelen V,Koppen G,Schoeters G,Van Loon H,Vlietinck R

更新日期：2006-06-01 00:00:00

abstract：:In recent years there has been an increasing focus in environmental risk assessment on children as a potentially susceptible population. There also has been growing recognition of the need for a systematic approach for organizing, evaluating, and incorporating the available data on children's susceptibilities in risk ...

journal_title：Environmental health perspectives

authors： Daston G,Faustman E,Ginsberg G,Fenner-Crisp P,Olin S,Sonawane B,Bruckner J,Breslin W,McLaughlin TJ

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Organophosphate developmental neurotoxicity involves multiple mechanisms converging on neural cell replication and differentiation. OBJECTIVES:We evaluated mechanisms contributing to the adverse effects of chlorpyrifos (CPF) on DNA synthesis, cell number and size, and cell signaling mediated by adenylyl cyc...

journal_title：Environmental health perspectives

authors： Slotkin TA,MacKillop EA,Ryde IT,Seidler FJ

更新日期：2007-09-01 00:00:00

abstract：:Nationwide, 45 states issue health advisories for sport fish consumers. Chemical contaminants in some Great Lakes (GL) sport fish include compounds suspected of causing adverse reproductive and developmental effects. Although advisories to reduce consumption of contaminated fish, especially by women, have been issued ...

journal_title：Environmental health perspectives

authors： Tilden J,Hanrahan LP,Anderson H,Palit C,Olson J,Kenzie WM

更新日期：1997-12-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are widespread, low-level environmental pollutants associated with adverse health effects such as immune suppression and teratogenicity. There is increasing evidence that some PCB compounds are capable of disrupting reproductive and endocrine function in fish, birds, and mammals, inclu...

journal_title：Environmental health perspectives

authors： Bergeron JM,Crews D,McLachlan JA

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Whether there is a causal relation between long-term exposure to traffic and asthma development is so far not clear. This may be explained by inaccurate exposure assessment. OBJECTIVE:We investigated the associations of long-term traffic-related exposures with asthma onset assessed retrospectively and respi...

journal_title：Environmental health perspectives

authors： Oftedal B,Nystad W,Brunekreef B,Nafstad P

更新日期：2009-05-01 00:00:00

abstract：:A meeting on Marine Biomedical Research, sponsored by the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health and the Smithsonian Institution Museum of Natural History, was attended by approximately 125 scientists, directors and representatives from many of the country's marine b...

journal_title：Environmental health perspectives

authors： Bessey O

更新日期：1976-02-01 00:00:00

abstract：:This working paper summarizes the known ultrastructural and biochemical effects of lead, mercury, cadmium, and arsenic on subcellular organelle systems following in vivo administration. Documented metal-induced alterations in nuclear, mitochondrial, microsomal, and lysosomal functions are discussed in relation to thei...

journal_title：Environmental health perspectives

authors： Fowler BA

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Per- and polyfluoroalkyl substances (PFAS) are widespread persistent organic pollutants and endocrine disruptors. High doses of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) exposure can cause pregnancy loss and infant deaths in animals, but the associations between PFAS exposures and...

journal_title：Environmental health perspectives

authors： Liew Z,Luo J,Nohr EA,Bech BH,Bossi R,Arah OA,Olsen J

更新日期：2020-04-01 00:00:00

abstract：:Restriction-fragment-length polymorphism analysis was performed on several different types of human cancers, including carcinoma of the uterine cervix, neuroblastoma, hepatocellular carcinoma, pheochromocytoma, stomach cancer, and small-cell lung carcinoma (SCLC), to determine the chromosomal loci of putative tumor-su...

journal_title：Environmental health perspectives

authors： Yokota J,Sugimura T,Terada M

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Numerous man-made pollutants activate the aryl hydrocarbon receptor (AhR) and are risk factors for type 2 diabetes. AhR signaling also affects molecular clock genes to influence glucose metabolism. OBJECTIVE:We investigated mechanisms by which AhR activation affects glucose metabolism. METHODS:Glucose tole...

journal_title：Environmental health perspectives

authors： Wang C,Xu CX,Krager SL,Bottum KM,Liao DF,Tischkau SA

更新日期：2011-12-01 00:00:00

abstract：:Repeated inhalation of silica dust can lead to inflammation and fibrosis in human lung and in experimental animal models. The alveolar macrophage is believed to play a pivotal role in this process. Numerous macrophage-derived growth factors, cytokines, and arachidonic acid metabolites have been shown to contribute to ...

journal_title：Environmental health perspectives

authors： Koren HS,Joyce M,Devlin RB,Becker S,Driscoll K,Madden MC

更新日期：1992-07-01 00:00:00

abstract：:The available data on the influence of selenium on the toxicity of methylmercury and of methylmercury on selenium as a nutrient and toxic agent are reviewed. Selenium as selenite has a relative protective effect on acute and subacute toxicity of methylmercury in the rat and the quail. The protective mechanism is far f...

journal_title：Environmental health perspectives

authors： Skerfving S

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Psychological sequelae are among the most pronounced effects in populations following exposure to oil spills. Women in particular represent a vulnerable yet influential population but have remained relatively understudied with respect to the Deepwater Horizon oil spill (DHOS). OBJECTIVE:To describe the rela...

journal_title：Environmental health perspectives

authors： Rung AL,Gaston S,Oral E,Robinson WT,Fontham E,Harrington DJ,Trapido E,Peters ES

更新日期：2016-09-01 00:00:00

abstract：:Comamonas testosteroni YZW-D was isolated from Passaic River sediment for its ability to degrade isophthalate and terephthalate. Degradation of the two isomeric compounds proceeds via separately inducible catabolic pathways that converge at protocatechuate. Analysis of the catabolic pathways by which these two isomers...

journal_title：Environmental health perspectives

authors： Wang YZ,Zhou Y,Zylstra GJ

更新日期：1995-06-01 00:00:00

abstract：:Under a mandate from the U.S. Congress, the National Toxicology Program (NTP) of the U.S. Department of Health and Human Services conducts animal bioassays for carcinogenicity of potentially toxic chemicals to which the U.S. population might be exposed. Methyleugenol, a natural as well as synthesized substance, was no...

journal_title：Environmental health perspectives

authors： Schecter A,Lucier GW,Cunningham ML,Abdo KM,Blumenthal G,Silver AG,Melnick R,Portier C,Barr DB,Barr JR,Stanfill SB,Patterson DG Jr,Needham LL,Stopford W,Masten S,Mignogna J,Tung KC

更新日期：2004-05-01 00:00:00

abstract：:Human health and aquatic animal health are organically related at three distinct interfaces. Aquatic animals serve as important contributors to the nutritional protein, lipid, and vitamin requirements of humans; as carriers and transmitters of many infectious and parasitic diseases to which humans are susceptible; and...

journal_title：Environmental health perspectives

authors： Dawe CJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Several per- and polyfluoroalkyl substances (PFAS) are ubiquitous anthropogenic pollutants almost universally detected in humans. Experimental evidence indicates that PFAS alter glucose metabolism and insulin secretion. However, epidemiological studies have yielded inconsistent results. OBJECTIVE:We sought ...

journal_title：Environmental health perspectives

authors： Cardenas A,Gold DR,Hauser R,Kleinman KP,Hivert MF,Calafat AM,Ye X,Webster TF,Horton ES,Oken E

更新日期：2017-10-02 00:00:00

abstract：BACKGROUND:The impact of prenatal lead exposure on neurodevelopment remains unclear in terms of consistency, the trimester of greatest vulnerability, and the best method for estimating fetal lead exposure. OBJECTIVE:We studied prenatal lead exposure's impact on neurodevelopment using repeated measures of fetal dose as...

journal_title：Environmental health perspectives

authors： Hu H,Téllez-Rojo MM,Bellinger D,Smith D,Ettinger AS,Lamadrid-Figueroa H,Schwartz J,Schnaas L,Mercado-García A,Hernández-Avila M

更新日期：2006-11-01 00:00:00

abstract：:The National Urban Air Toxics Research Center (NUATRC) hosted its first scientific workshop in 1994 that focused on possible relationships between air toxics and asthma. From that meeting came recommendations for future research including a need for more complete individual personal exposure assessments so that determ...

journal_title：Environmental health perspectives

authors： Larsen GL,Beskid C,Shirnamé-Moré L

更新日期：2002-08-01 00:00:00

abstract：:The progression of the cell cycle is controlled by the action of both positive and negative growth regulators. The key players in this activity include a family of cyclins and cyclin-dependent kinases, which are themselves regulated by other kinases and phosphatases. Maintenance of balanced cell cycle controls may be ...

journal_title：Environmental health perspectives

authors： Afshari CA,Barrett JC

更新日期：1993-12-01 00:00:00

abstract：:Metal ions form complexes with naturally occurring complexing agents or ligands released from industrial activity. The metal complexes are thereby mobilized and transported in environmental and biological systems. The impact of such metal complexes depends on the metal complex species that are kinetically and thermody...

journal_title：Environmental health perspectives

authors： Fernando Q

更新日期：1995-02-01 00:00:00

abstract：:The lung epithelium resorbs alveolar fluid through combined action of sodium channels and the sodium pump, Na,K-ATPase. The lung often is exposed to hyperoxia in disease states and hyperoxia generates a mixture of reactive oxygen species. In vivo and in vitro exposure of rat lung and alveolar type II cells, respective...

journal_title：Environmental health perspectives

authors： Wendt CH,Sharma R,Bair R,Towle H,Ingbar DH

更新日期：1998-10-01 00:00:00

abstract：:The subchronic inhalation toxicology of ethylene glycol monoethyl ether (EGEE) was evaluated in rats and rabbits using a 13-week exposure regimen. Groups of 20 rabbits (10 M, 10 F) and 30 rats (15 M, 15 F) were exposed to a vapor of 25 ppm, 100 ppm, or 400 ppm, 6 hr/day, 5 days/week. The control groups received air on...

journal_title：Environmental health perspectives

authors： Barbee SJ,Terrill JB,DeSousa DJ,Conaway CC

更新日期：1984-08-01 00:00:00

abstract：:The formamidines, a relatively new group of acaricide-insecticides, are novel both in their range of biological activities and in their mode of action, which is presently unknown. This paper is a review of the historical development, properties, structures, uses, and chemistry of this group of pesticides, with particu...

journal_title：Environmental health perspectives

authors： Hollingworth RM

更新日期：1976-04-01 00:00:00