Metal speciation in environmental and biological systems.

abstract：:The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials. The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model. While acellular and in vitro systems are important for initial evaluat...

journal_title：Environmental health perspectives

authors： Bernstein DM,Mast R,Anderson R,Hesterberg TW,Musselman R,Kamstrup O,Hadley J

更新日期：1994-10-01 00:00:00

abstract：:Determination of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in fly ash and cinders collected from nine municipal incinerators in Japan was made. The concentrations of PCDDs and PCDFs in this study were generally in the same range as those in Europe and North America. However, t...

journal_title：Environmental health perspectives

authors： Wakimoto T,Tatsukawa R

更新日期：1985-02-01 00:00:00

abstract：:Chromate is an established human carcinogen. There have been many studies of the reactivity of chromate aimed at improving understanding of chromate toxicity. In the present paper a number of conclusions of these studies are reviewed and considered in the light of new results obtained in our laboratories. A number of ...

journal_title：Environmental health perspectives

authors： O'Brien P,Kortenkamp A

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. OBJECTIVES:This study was designed to evaluate whether pren...

journal_title：Environmental health perspectives

authors： Xia W,Du X,Zheng T,Zhang B,Li Y,Bassig BA,Zhou A,Wang Y,Xiong C,Li Z,Yao Y,Hu J,Zhou Y,Liu J,Xue W,Ma Y,Pan X,Peng Y,Xu S

更新日期：2016-01-01 00:00:00

abstract：:Repeated inhalation of silica dust can lead to inflammation and fibrosis in human lung and in experimental animal models. The alveolar macrophage is believed to play a pivotal role in this process. Numerous macrophage-derived growth factors, cytokines, and arachidonic acid metabolites have been shown to contribute to ...

journal_title：Environmental health perspectives

authors： Koren HS,Joyce M,Devlin RB,Becker S,Driscoll K,Madden MC

更新日期：1992-07-01 00:00:00

abstract：:Poly(vinyl chloride) resins are produced by four basic processes: suspension, emulsion, bulk and solution polymerization. PVC suspensions resins are usually relatively dust-free and granular with varying degrees of particle porosity. PVC emulsion resins are small particle powders containing very little free monomer. B...

journal_title：Environmental health perspectives

authors： Wheeler RN Jr

更新日期：1981-10-01 00:00:00

abstract：:The carcinogenic activities of sodium chlorite in B6C3F1 mice were examined. Sodium chlorite was given at concentrations of 0 (control), 0.025% (low dose), or 0.05% (high dose) in the drinking water of 150 female and 150 male mice for 80 weeks, after which time the animals were returned to distilled water without sodi...

journal_title：Environmental health perspectives

authors： Yokose Y,Uchida K,Nakae D,Shiraiwa K,Yamamoto K,Konishi Y

更新日期：1987-12-01 00:00:00

abstract：:The genetic toxicology databases for chemicals that have been tested extensively are generally composed of inconsistent responses from a diverse set of assays. Consequently, difficulties arise when the data are evaluated for classifying the agent or for assessing the chemical's hazard potential. Several years ago, the...

journal_title：Environmental health perspectives

authors： Brusick D

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Studies suggest that phthalate exposures may adversely affect child respiratory health. OBJECTIVES:We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEH...

journal_title：Environmental health perspectives

authors： Whyatt RM,Perzanowski MS,Just AC,Rundle AG,Donohue KM,Calafat AM,Hoepner LA,Perera FP,Miller RL

更新日期：2014-10-01 00:00:00

abstract：:Environmental health and environmental quality issues along the U.S.-Mexico border have been of concern for several years. The enactment of the North American Free Trade Agreement and the presence of the maquiladoras (foreign-owned industries using imported raw materials) have intensified those concerns recently. Effo...

journal_title：Environmental health perspectives

authors： Carter DE,Peña C,Varady R,Suk WA

更新日期：1996-06-01 00:00:00

abstract：:Metabolic enzymes involved in benzene activation or detoxification, including NAD(P)H, quinone oxidoreductase 1 (NQO1), cytochrome P450 2E1 (CYP2E1), myeloperoxidase (MPO), glutathione-S-transferase mu-1 (GSTM1), and glutathione-S-transferase theta-1 (GSTT1), were studied for their roles in human susceptibility to ben...

journal_title：Environmental health perspectives

authors： Wan J,Shi J,Hui L,Wu D,Jin X,Zhao N,Huang W,Xia Z,Hu G

更新日期：2002-12-01 00:00:00

abstract：:There is concern about the human health effects of inhalation of acid compounds found in urban air pollution. It was the purpose of this study to investigate three of these acid compounds, sulfur dioxide (SO2), sulfuric acid (H2SO4), and nitric acid (HNO3) in a group of allergic adolescent subjects. Subjects were expo...

journal_title：Environmental health perspectives

authors： Koenig JQ,Covert DS,Pierson WE

更新日期：1989-02-01 00:00:00

abstract：:The findings of studies investigating whether exposures to ionizing radiation before birth, either pre- or post-conception, increase the risk of childhood cancer have provoked much scientific controversy. An epidemiological association between the abdominal exposure of pregnant women to diagnostic X-rays and childhood...

journal_title：Environmental health perspectives

authors： Wakeford R

更新日期：1995-11-01 00:00:00

abstract：:This paper reports the results of a comprehensive survey of the effects of the accidental release of radiation caused by the accident at the Chernobyl nuclear power station in April 1986. The accident and the resulting release of radiation and radioactive products into the atmosphere produced the most serious environm...

journal_title：Environmental health perspectives

authors： Kulakov VI,Sokur TN,Volobuev AI,Tzibulskaya IS,Malisheva VA,Zikin BI,Ezova LC,Belyaeva LA,Bonartzev PD,Speranskaya NV

更新日期：1993-07-01 00:00:00

abstract：:Humans are exposed to a large number of environmental genotoxic agents. These can increase the probability that somatic mutation will occur. The use of genotoxicity testing is essential for assessment of potential human toxicity so that hazards can be prevented. Cytogenetic monitoring of human populations exposed to c...

journal_title：Environmental health perspectives

authors： Anwar WA

更新日期：1994-10-01 00:00:00

abstract：:The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was i...

journal_title：Environmental health perspectives

authors： Mazzullo M,Bartoli S,Bonora B,Colacci A,Grilli S,Lattanzi G,Niero A,Turina MP,Parodi S

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:We reviewed epidemiologic evidence related to occupational pesticide exposures and cancer incidence in the Agricultural Health Study (AHS) cohort. DATA SOURCES:Studies were identified from the AHS publication list available at http://aghealth.nci.nih.gov as well as through a Medline/PubMed database search in...

journal_title：Environmental health perspectives

authors： Weichenthal S,Moase C,Chan P

更新日期：2010-08-01 00:00:00

abstract：:In 1998, the Helicobacter pylori [(13)C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in t...

journal_title：Environmental health perspectives

authors： Herbarth O,Krumbiegel P,Fritz GJ,Richter M,Schlink U,Müller DM,Richter T

更新日期：2001-06-01 00:00:00

abstract：:Outdoor ambient air pollutant exposures in communities are relevant to the acute exacerbation and possibly the onset of asthma. However, the complexity of pollutant mixtures and etiologic heterogeneity of asthma has made it difficult to identify causal components in those mixtures. Occupational exposures associated wi...

journal_title：Environmental health perspectives

authors： Delfino RJ

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:According to the 2007 National Research Council report Toxicology for the Twenty-First Century, modern methods (e.g., "omics," in vitro assays, high-throughput testing, computational methods) will lead to the emergence of a new approach to toxicology. The Salmonella mammalian microsome mutagenicity assay has...

journal_title：Environmental health perspectives

authors： Claxton LD,Umbuzeiro Gde A,DeMarini DM

更新日期：2010-11-01 00:00:00

abstract：:Most of the general population is exposed to carbaryl and other contemporary-use insecticides at low levels. Studies of laboratory animals, in addition to limited human data, show an association between carbaryl exposure and decreased semen quality. In the present study we explored whether environmental exposures to 1...

journal_title：Environmental health perspectives

authors： Meeker JD,Ryan L,Barr DB,Herrick RF,Bennett DH,Bravo R,Hauser R

更新日期：2004-12-01 00:00:00

abstract：:With this research I tested the hypothesis that individual preferences for specific ecosystem components and restorative environments are significantly associated with quality of life (QOL). A total of 379 human subjects responded to a structured 18-item questionnaire on topophilia and to the 26-item World Health Orga...

journal_title：Environmental health perspectives

authors： Ogunseitan OA

更新日期：2005-02-01 00:00:00

abstract：:Ecological risk assessment can be enhanced with predictive models for metal toxicity. Modelings of published data were done under the simplifying assumption that intermetal trends in toxicity reflect relative metal-ligand complex stabilities. This idea has been invoked successfully since 1904 but has yet to be applied...

journal_title：Environmental health perspectives

authors： Newman MC,McCloskey JT,Tatara CP

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:The toxicity of many xenobiotic compounds is believed to involve oxidative injury to cells. Direct assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achievable. Development of genetically encoded probes designed for monitoring intracellular redox changes represent...

journal_title：Environmental health perspectives

authors： Gibbs-Flournoy EA,Simmons SO,Bromberg PA,Dick TP,Samet JM

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Humans living near industrial point emissions can experience high levels of exposures to air pollutants. Map Ta Phut Industrial Estate in Thailand is the location of the largest steel, oil refinery, and petrochemical factory complexes in Southeast Asia. Air pollution is an important source of oxidative stres...

journal_title：Environmental health perspectives

authors： Peluso M,Srivatanakul P,Munnia A,Jedpiyawongse A,Ceppi M,Sangrajrang S,Piro S,Boffetta P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A critical question regarding the association between short-term exposure to ozone and mortality is the extent to which this relationship is confounded by ambient exposure to particles. OBJECTIVES:We investigated whether particulate matter < 10 and < 2.5 microm in aerodynamic diameter (PM(10) and PM(2.5)) i...

journal_title：Environmental health perspectives

authors： Bell ML,Kim JY,Dominici F

更新日期：2007-11-01 00:00:00

abstract：:Locating geographic hot spots of cancer may lead to new causal hypotheses and ultimately to new knowledge of cancer-causing factors. The Cape Cod region of Massachusetts has experienced elevated incidence of breast cancer compared with statewide averages. The origins of the excess remain largely unexplained, even afte...

journal_title：Environmental health perspectives

authors： Paulu C,Aschengrau A,Ozonoff D

更新日期：2002-05-01 00:00:00

abstract：:We analyzed questionnaire and physician examination data for 1560 new immigrants from the former USSR divided into three groups by potential exposure to Chernobyl radiation. Two groups were chosen according to soil contamination by cesium-137 at former residences, as confirmed by our findings in a 137Cs body burden st...

journal_title：Environmental health perspectives

authors： Kordysh EA,Goldsmith JR,Quastel MR,Poljak S,Merkin L,Cohen R,Gorodischer R

更新日期：1995-10-01 00:00:00

abstract：:Perchlorate (ClO4-) has been detected in groundwater sources in numerous communities in California and other parts of the United States, raising concerns about potential impacts on health. For California communities where ClO4- was tested in 1997 and 1998, we evaluated the prevalence of primary congenital hypothyroidi...

journal_title：Environmental health perspectives

authors： Buffler PA,Kelsh MA,Lau EC,Edinboro CH,Barnard JC,Rutherford GW,Daaboul JJ,Palmer L,Lorey FW

更新日期：2006-05-01 00:00:00

abstract：:Uranium accumulates in bone, affects bone metabolism in laboratory animals, and when ingested in drinking water increases urinary excretion of calcium and phosphate, important components in the bone structure. However, little is known about bone effects of ingested natural uranium in humans. We studied 146 men and 142...

journal_title：Environmental health perspectives

authors： Kurttio P,Komulainen H,Leino A,Salonen L,Auvinen A,Saha H

更新日期：2005-01-01 00:00:00