Metal speciation in environmental and biological systems.


:Metal ions form complexes with naturally occurring complexing agents or ligands released from industrial activity. The metal complexes are thereby mobilized and transported in environmental and biological systems. The impact of such metal complexes depends on the metal complex species that are kinetically and thermodynamically stable in these homogeneous and heterogeneous systems. The distribution of metal complex species in these complex systems can be calculated from available formation constant data. This article describes the importance of verifying the validity of these calculations by employing experimental techniques that can speciate metal complexes.


Fernando Q




Has Abstract


1995-02-01 00:00:00








103 Suppl 1


  • Long-Term Exposure to Transportation Noise in Relation to Development of Obesity—a Cohort Study.

    abstract:BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Pyko A,Eriksson C,Lind T,Mitkovskaya N,Wallas A,Ögren M,Östenson CG,Pershagen G

    更新日期:2017-11-20 00:00:00

  • The role of cell calcium in current approaches to toxicology.

    abstract::All cells contain elaborate systems for the spatial and temporal regulation of the calcium ion, [Ca2+]i, and diverse Ca2+ receptor and biochemical response systems that are regulated by these changes in [Ca2+]i. Toxicants that perturb the mobilization or homeostasis of [Ca2+]i will place the regulation of these proces...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Pounds JG

    更新日期:1990-03-01 00:00:00

  • Relationships among polycyclic aromatic hydrocarbon-DNA adducts, proximity to the World Trade Center, and effects on fetal growth.

    abstract::Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants released by the World Trade Center (WTC) fires and various urban combustion sources. Benzo[a]pyrene (BaP) is a representative member of the class of PAHs. PAH-DNA adducts, or BaP-DNA adducts as their proxy, provide a measure of chemical-specific genetic dama...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Perera FP,Tang D,Rauh V,Lester K,Tsai WY,Tu YH,Weiss L,Hoepner L,King J,Del Priore G,Lederman SA

    更新日期:2005-08-01 00:00:00

  • General subcellular effects of lead, mercury, cadmium, and arsenic.

    abstract::This working paper summarizes the known ultrastructural and biochemical effects of lead, mercury, cadmium, and arsenic on subcellular organelle systems following in vivo administration. Documented metal-induced alterations in nuclear, mitochondrial, microsomal, and lysosomal functions are discussed in relation to thei...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Fowler BA

    更新日期:1978-02-01 00:00:00

  • Environmental practices for biomedical research facilities.

    abstract::As a result of the Leadership Conference on Biomedical Research and the Environment, the Facilities Committee focused its work on the development of best environmental practices at biomedical research facilities at the university and independent research facility level as well as consideration of potential involvement...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Medlin EL,Grupenhoff JT

    更新日期:2000-12-01 00:00:00

  • Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research.

    abstract::Biomedical developments in the 21st century provide an unprecedented opportunity to gain a dynamic systems-level and human-specific understanding of the causes and pathophysiologies of disease. This understanding is a vital need, in view of continuing failures in health research, drug discovery, and clinical translati...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Langley G,Austin CP,Balapure AK,Birnbaum LS,Bucher JR,Fentem J,Fitzpatrick SC,Fowle JR 3rd,Kavlock RJ,Kitano H,Lidbury BA,Muotri AR,Peng SQ,Sakharov D,Seidle T,Trez T,Tonevitsky A,van de Stolpe A,Whelan M,Willett C

    更新日期:2015-11-01 00:00:00

  • Legislative aspects of hazardous waste management.

    abstract::In the fall of 1976 Congress enacted the Resource Conservation and Recovery Act, commonly referred to as RCRA. The objective of the statute is to create an orderly system for the generation, handling and disposal of hazardous waste by means of a comprehensive tracking and record keeping mechanism. RCRA does not regula...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Friedman M

    更新日期:1983-02-01 00:00:00

  • Estimation of gene frequency and test for Hardy-Weinberg equilibrium in the HLA system.

    abstract::This paper concerns the testing for Hardy-Weinberg equilibrium and the estimation of gene frequency in the human leukocyte antigens (HLA) system. An extensive simulation study for both testing and estimation is given for investigating the performance of the projection method by Eguchi and Matsuura, which has a closed ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Matsuura M,Eguchi S

    更新日期:1990-07-01 00:00:00

  • The Prevalence and Use of Walking Loops in Neighborhood Parks: A National Study.

    abstract:BACKGROUND:Previous studies indicate that the design of streets and sidewalks can influence physical activity among residents. Park features also influence park use and park-based physical activity. Although individuals can walk on streets and sidewalks, walking loops in parks offer a setting to walk in nature and to a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Cohen DA,Han B,Evenson KR,Nagel C,McKenzie TL,Marsh T,Williamson S,Harnik P

    更新日期:2017-02-01 00:00:00

  • Effects of the workplace on fertility and related reproductive outcomes.

    abstract::This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Baranski B

    更新日期:1993-07-01 00:00:00

  • Outdoor Light at Night and Breast Cancer Incidence in the Nurses' Health Study II.

    abstract:BACKGROUND:Animal and epidemiologic studies suggest that exposure to light at night (LAN) may disrupt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regulation, leading to increased breast cancer risk. OBJECTIVES:We examined the association between residential outdoor LAN ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: James P,Bertrand KA,Hart JE,Schernhammer ES,Tamimi RM,Laden F

    更新日期:2017-08-17 00:00:00

  • Risk screening for exposure to groundwater pollution in a wastewater irrigation district of the Mexico City region.

    abstract::Untreated wastewater from the Mexico City basin has been used for decades to irrigate cropland in the Mezquital Valley, State of Hidalgo, Mexico. Excess irrigation water recharges the near-surface aquifer that is used as a domestic water supply source. We assessed the groundwater quality of three key groundwater sourc...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Downs TJ,Cifuentes-García E,Suffet IM

    更新日期:1999-07-01 00:00:00

  • Oxidatively damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes.

    abstract:BACKGROUND:C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event i...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Folkmann JK,Risom L,Jacobsen NR,Wallin H,Loft S,Møller P

    更新日期:2009-05-01 00:00:00

  • Is there evidence for synergy among air pollutants in causing health effects?

    abstract:BACKGROUND:Environmental air pollutants are inhaled as complex mixtures, but the long dominant focus of monitoring and research on individual pollutants has provided modest insight into pollutant interactions that may be important to health. Trends toward managing multiple pollutants to maximize aggregate health gains ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Mauderly JL,Samet JM

    更新日期:2009-01-01 00:00:00

  • Significance of high soil lead concentrations for childhood lead burdens.

    abstract::The lead exposure of children and their mothers has been studied in two towns with mean soil lead contents of 900 and 400 ppm. No significant difference in blood or fecal lead contents was demonstrated between the two populations, but a small difference in hair lead content was shown. The blood lead content of childre...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Barltrop D,Strehlow CD,Thorton I,Webb JS

    更新日期:1974-05-01 00:00:00

  • Genetic toxicology of phthalate esters: mutagenic and other genotoxic effects.

    abstract::The effects of DEHP on sperm morphology and on peripheral blood micronuclei were studied for 12 weeks following five subacute IP injections of DEHP at 1/6, 1/12, and 1/60 of the LD50 per day. Sperm morphology was examined in both adult mice and rats, while peripheral blood micronuclei were scored in mice up to 4 weeks...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Douglas GR,Hugenholtz AP,Blakey DH

    更新日期:1986-03-01 00:00:00

  • The role of syntrophic associations in sustaining anaerobic mineralization of chlorinated organic compounds.

    abstract::Stable associations of syntrophic fermentative organisms and populations that consume fermentation products play key roles in the anaerobic biodegradation of chlorinated organic contaminants. The involvement of these syntrophic populations is essential for mineralization of chlorinated aromatic compounds under methano...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Becker JG,Berardesco G,Rittmann BE,Stahl DA

    更新日期:2005-03-01 00:00:00

  • Hearing loss in workers exposed to toluene and noise.

    abstract::In this study we investigated the risk of hearing loss among workers exposed to both toluene and noise. We recruited 58 workers at an adhesive materials manufacturing plant who were exposured to both toluene and noise [78.6-87.1 A-weighted decibels; dB(A)], 58 workers exposed to noise only [83.5-90.1 dB(A)], and 58 ad...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Chang SJ,Chen CJ,Lien CH,Sung FC

    更新日期:2006-08-01 00:00:00

  • Effects of processing and cooking on PBB residues.

    abstract::To study the effect of processing on polybrominated biphenyl (PBB) levels, milk from four dairy herds containing less than 0.3 ppm (fat basis) of physiologically incorporated PBBs was presented individually into cream, skim milk, butter, and stirred curd cheese. Pasteurized and freeze-dried whole milk, skim milk, and ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Zabik ME,Johnson TM,Smith S

    更新日期:1978-04-01 00:00:00

  • Examples of uses of databases for quantitative and qualitative correlation studies between genotoxicity and carcinogenicity.

    abstract::In this paper we give some examples of using databases of genotoxicity and carcinogenicity for quantitative and qualitative correlation studies between short-term tests and carcinogenicity. The quality of the databases is obviously important, but one of the major deficiencies of present databases is that they are too ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Parodi S,Malacarne D,Taningher M

    更新日期:1991-12-01 00:00:00

  • Municipal solid wastes and their disposal.

    abstract::A brief overview is given of the sources, characteristics, and toxic constituents of municipal solid wastes. Several methods are presented for handling, treating, and disposal of solid wastes. Monitoring the landfill site is necessary; there has been a trend to recognize that municipal solid wastes may be hazardous an...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Stone R

    更新日期:1978-12-01 00:00:00

  • Using metal-ligand binding characteristics to predict metal toxicity: quantitative ion character-activity relationships (QICARs).

    abstract::Ecological risk assessment can be enhanced with predictive models for metal toxicity. Modelings of published data were done under the simplifying assumption that intermetal trends in toxicity reflect relative metal-ligand complex stabilities. This idea has been invoked successfully since 1904 but has yet to be applied...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Newman MC,McCloskey JT,Tatara CP

    更新日期:1998-12-01 00:00:00

  • Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain.

    abstract:BACKGROUND:Rodent models for urban air pollution show consistent induction of inflammatory responses in major brain regions. However, the initial impact of air pollution particulate material on olfactory gateways has not been reported. OBJECTIVE:We evaluated the olfactory neuroepithelium (OE) and brain regional respon...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Cheng H,Saffari A,Sioutas C,Forman HJ,Morgan TE,Finch CE

    更新日期:2016-10-01 00:00:00

  • Cellular and humoral immune abnormalities in Gulf War veterans.

    abstract::We examined 100 symptomatic Gulf War veterans (patients) and 100 controls for immunologic assays. The veterans and controls were compared for the percentage of T cells (CD3); B cells (CD19); helper:suppressor (CD4:CD8) ratio; natural killer (NK) cell activity; mitogenic response to phytohemagglutin (PHA) and pokeweed ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Vojdani A,Thrasher JD

    更新日期:2004-06-01 00:00:00

  • The biological exposure indices: a key component in protecting workers from toxic chemicals.

    abstract::Biological monitoring of exposure to chemicals in the workplace is an important component of exposure assessment and prevention of adverse health effects. It should be employed in conjunction with ambient air monitoring to provide information on the absorbed dose of a chemical agent and the effect of all routes of exp...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审


    authors: Morgan MS

    更新日期:1997-02-01 00:00:00

  • DNA damage-inducible genes as biomarkers for exposures to environmental agents.

    abstract::A biodosimetric approach to determine alpha-particle dose to the respiratory tract epithelium from known exposures to radon has been developed in the rat. Cytotoxicity assays have been used to obtain dose-conversion factors for cumulative exposures typical of those encountered by underground uranium miners. However, t...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Johnson NF,Carpenter TR,Jaramillo RJ,Liberati TA

    更新日期:1997-06-01 00:00:00

  • Transfer and Metabolism of the Xenoestrogen Zearalenone in Human Perfused Placenta.

    abstract:BACKGROUND:Pregnancy is a sensitive condition during which adverse environmental exposures should be monitored thoroughly and minimized whenever possible. In particular, the hormone balance during gestation is delicate, and disturbance may cause acute or chronic long-term health effects. A potential endocrine disruptio...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Warth B,Preindl K,Manser P,Wick P,Marko D,Buerki-Thurnherr T

    更新日期:2019-10-01 00:00:00

  • Methylarsonous acid transport by aquaglyceroporins.

    abstract::Many mammals methylate trivalent inorganic arsenic in liver to species that are released into the bloodstream and excreted in urine and feces. This study addresses how methylated arsenicals pass through cell membranes. We have previously shown that aquaglyceroporin channels, including Escherichia coli GlpF, Saccharomy...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Liu Z,Styblo M,Rosen BP

    更新日期:2006-04-01 00:00:00

  • Protein kinase C activity and the relations between blood lead and neurobehavioral function in lead workers.

    abstract::At picomolar concentrations, lead activates protein kinase C (PKC). This activation has been implicated in the neurotoxicity of lead. No prior study has evaluated the association of PKC activity with neurobehavioral function in humans. The purpose of this study was to determine whether PKC activity is associated with ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Hwang KY,Lee BK,Bressler JP,Bolla KI,Stewart WF,Schwartz BS

    更新日期:2002-02-01 00:00:00

  • Health status of Japanese and Taiwanese after exposure to contaminated rice oil.

    abstract::Mass poisonings, called yusho and yu-cheng, occurred in western Japan in 1968 and central Taiwan in 1979, respectively. These occurrences were separately caused by ingestion of rice oils contaminated with polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs) and polychlorinated quaterphenyls. The tot...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章


    authors: Masuda Y

    更新日期:1985-05-01 00:00:00