Comparative development of the nervous, respiratory, and cardiovascular systems.

abstract：:To evaluate the effectiveness of mass screening for uterine cancer in Japan, we compared the changes in the age-adjusted rates of potential years of life lost (PYLL) due to uterine cancer between 1969 and 1972 to 1973 through 1977 between the high coverage-rate (intensively screened) areas and the comparable control a...

journal_title：Environmental health perspectives

authors： Kuroishi T,Hirose K,Tominaga S

更新日期：1990-07-01 00:00:00

abstract：:In this study, we explored the efficacy of upper-room ultraviolet germicidal irradiation (UVGI) in reducing the concentration of Serratia marcescens and Mycobacterium bovis bacille Calmette-Guérin (BCG) aerosols in enclosed places. We constructed a facility (4.5 m x 3 m x 2.9 m) in which both ceiling- and wall-mounted...

journal_title：Environmental health perspectives

authors： Ko G,First MW,Burge HA

更新日期：2002-01-01 00:00:00

abstract：:We examined 100 symptomatic Gulf War veterans (patients) and 100 controls for immunologic assays. The veterans and controls were compared for the percentage of T cells (CD3); B cells (CD19); helper:suppressor (CD4:CD8) ratio; natural killer (NK) cell activity; mitogenic response to phytohemagglutin (PHA) and pokeweed ...

journal_title：Environmental health perspectives

authors： Vojdani A,Thrasher JD

更新日期：2004-06-01 00:00:00

abstract：:Because of rampant concern that estrogenic chemicals in the environment may be adversely affecting the health of humans and wildlife, reliable methods for detecting and characterizing estrogenic chemicals are needed. It is important that general agreement be reached on which tests to use and that these tests then be a...

journal_title：Environmental health perspectives

authors： Shelby MD,Newbold RR,Tully DB,Chae K,Davis VL

更新日期：1996-12-01 00:00:00

abstract：:This article briefly summarizes the epidemiology of the health effects of fine particulate air pollution, provides an early, somewhat speculative, discussion of the contribution of epidemiology to evaluating biologic mechanisms, and evaluates who's at risk or is susceptible to adverse health effects. Based on prelimin...

journal_title：Environmental health perspectives

authors： Pope CA 3rd

更新日期：2000-08-01 00:00:00

abstract：:Phthalates are a group of multifunctional chemicals used in consumer and personal care products, plastics, and medical devices. Laboratory studies show that some phthalates are reproductive and developmental toxicants. Recently, human studies have shown measurable levels of several phthalates in most of the U.S. gener...

journal_title：Environmental health perspectives

authors： Hauser R,Duty S,Godfrey-Bailey L,Calafat AM

更新日期：2004-05-01 00:00:00

abstract：:One of the most serious consequences of cancer therapy is the development of a second cancer, especially leukemia. Several distinct subsets of therapy-related leukemia can now be distinguished. Classic therapy-related myeloid leukemia typically occurs 5 to 7 years after exposure to alkylating agents and/or irradiation...

journal_title：Environmental health perspectives

authors： Larson RA,LeBeau MM,Vardiman JW,Rowley JD

更新日期：1996-12-01 00:00:00

abstract：:A microscopic, ultrastructural, and morphometric study was made of the gills of tench (Tinca tinca, L.) subjected to acute experimental lead nitrate poisoning. Twenty-one adult tench were subjected to poisoning and a further 22 were used as controls. Lesions were characterized by the appearance of edema and epithelial...

journal_title：Environmental health perspectives

authors： Roncero V,Vincente JA,Redondo E,Gãzquez A,Duran E

更新日期：1990-11-01 00:00:00

abstract：:Asbestos and silica are well-known fibrogenic dusts. However, there is no comprehensive understanding of the molecular and cellular events that lead to fibrosis as a consequence of asbestos or silica inhalation. Previous studies have shown that asbestos stimulates superoxide anion production in alveolar macrophages th...

journal_title：Environmental health perspectives

authors： Holian A,Kelley K,Hamilton RF Jr

更新日期：1994-12-01 00:00:00

abstract：:Children may be more susceptible to exposures to environmental toxins than adults and may be more vulnerable to their effects. Because of this, the health care community and those responsible for children need to be alert to possible environmental factors in identifying and responding to the health problems of childre...

journal_title：Environmental health perspectives

authors： Goldman LR

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Experimental tools for studying the complex steroidogenic interactions that occur between placenta and fetus during human pregnancy are extremely limited. OBJECTIVES:We aimed to develop a co-culture model to study steroidogenesis by the human fetoplacental unit and its disruption by exposure to environmenta...

journal_title：Environmental health perspectives

authors： Hudon Thibeault AA,Deroy K,Vaillancourt C,Sanderson JT

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Adapting to extreme heat is becoming more critical as our climate changes. Previous research reveals that very few communities in the United States have programs to sufficiently prevent health problems during hot weather. OBJECTIVE:Our goal was to examine county-level local heat preparedness and response in...

journal_title：Environmental health perspectives

authors： White-Newsome JL,Ekwurzel B,Baer-Schultz M,Ebi KL,O'Neill MS,Anderson GB

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Hexavalent chromium [Cr(VI)] is recognized as a human carcinogen via inhalation. However, the molecular mechanisms by which Cr(VI) causes cancers are not well understood. OBJECTIVES:We evaluated cyclooxygenase-2 (COX-2) expression and the signaling pathway leading to this induction due to Cr(VI) exposure in...

journal_title：Environmental health perspectives

authors： Zuo Z,Cai T,Li J,Zhang D,Yu Y,Huang C

更新日期：2012-04-01 00:00:00

abstract：:Surface IR (infrared) modes of crystalline and fumed (amorphous) silica particles, calcined at temperatures up to 1095 degrees C, have been studied by Fourier transform infrared spectroscopy. The ability of these same particles to lyse cells has been measured by a hemolysis protocol. The untreated crystalline and amor...

journal_title：Environmental health perspectives

authors： Pandurangi RS,Seehra MS,Razzaboni BL,Bolsaitis P

更新日期：1990-06-01 00:00:00

abstract：:The significance of the environment for health is increasingly being recognized. There is a need for systematic approaches to assessment of environmental factors most relevant to health, health outcomes most influenced by the environment, and the relationships between them, as well as for approaches to representing th...

journal_title：Environmental health perspectives

authors： Kyle AD,Woodruff TJ,Axelrad DA

更新日期：2006-03-01 00:00:00

abstract：:Collaborative studies were performed to develop a functional assay for fish-killing activity produced by Pfiesteria piscicida. Eight cell lines were used to screen organic fractions and residual water fraction by using a 3-[4, 5-dimethylthiazol-(2-4)]-diphenyltetrazolium bromide cytotoxicity assay. Diethyl ether and a...

journal_title：Environmental health perspectives

authors： Fairey ER,Edmunds JS,Deamer-Melia NJ,Glasgow H Jr,Johnson FM,Moeller PR,Burkholder JM,Ramsdell JS

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Urbanization has been correlated with hypertension (HTN) in developing countries undergoing rapid economic and environmental transitions. OBJECTIVES:We examined the relationships among living environment (urban, suburban, and rural), day/night land surface temperatures (LST), and blood pressure in selected ...

journal_title：Environmental health perspectives

authors： Estes MG Jr,Al-Hamdan MZ,Crosson W,Estes SM,Quattrochi D,Kent S,McClure LA

更新日期：2009-12-01 00:00:00

abstract：:Elucidation of the role of vinyl chloride metabolites in the various reaction sequences which comprise the metabolic pathway, including the interaction of reactive metabolities with some purine and pyrimidine residues of target-organ DNA, provides some explanation for the (oncogenic) properties associated with the ori...

journal_title：Environmental health perspectives

authors： Hathway DE

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Tremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene. OBJECTIVE:We aimed t...

journal_title：Environmental health perspectives

authors： Ji JS,Power MC,Sparrow D,Spiro A 3rd,Hu H,Louis ED,Weisskopf MG

更新日期：2015-05-01 00:00:00

abstract：:Several examples of categorized data from epidemiological studies are analyzed to illustrate that more informative analysis than tests of independence can be performed by fitting models. All of the analyses fit into a unified conceptual framework that can be performed by weighted least squares. The methods presented s...

journal_title：Environmental health perspectives

authors： Grizzle JE,Koch GG

更新日期：1979-10-01 00:00:00

abstract：:U.S. chemical plants currently have potentially catastrophic vulnerabilities as terrorist targets. The possible consequences of these vulnerabilities echo from the tragedies of the Bhopal incident in 1984 to the terrorist attacks on 11 September 2001 and, most recently, Hurricanes Katrina and Rita. Findings from a 200...

journal_title：Environmental health perspectives

authors： Lippin TM,McQuiston TH,Bradley-Bull K,Burns-Johnson T,Cook L,Gill ML,Howard D,Seymour TA,Stephens D,Williams BK

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. OBJECTIVE:We aimed to assess the toxicity of well-characte...

journal_title：Environmental health perspectives

authors： Bastian S,Busch W,Kühnel D,Springer A,Meissner T,Holke R,Scholz S,Iwe M,Pompe W,Gelinsky M,Potthoff A,Richter V,Ikonomidou C,Schirmer K

更新日期：2009-04-01 00:00:00

abstract：:The purpose of the investigation is to study whether an increased mortality from certain causes exists in an area around the Rönnskärsverken smelter works in northern Sweden. Founded in 1928, this metallurgical plant processing mainly nonferrous metals has since its initial operations been using ore with a high arseni...

journal_title：Environmental health perspectives

authors： Pershagen G,Elinder CG,Bolander AM

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:The rapidly increasing dissemination of carbapenem-resistant Enterobacteriaceae (CRE) in both humans and animals poses a global threat to public health. However, the transmission of CRE between humans and animals has not yet been well studied. OBJECTIVES:We investigated the prevalence, risk factors, and dri...

journal_title：Environmental health perspectives

authors： Li J,Bi Z,Ma S,Chen B,Cai C,He J,Schwarz S,Sun C,Zhou Y,Yin J,Hulth A,Wang Y,Shen Z,Wang S,Wu C,Nilsson LE,Walsh TR,Börjesson S,Shen J,Sun Q,Wang Y

更新日期：2019-10-01 00:00:00

abstract：:This paper summarizes the clinical phenomenology of multiple chemical sensitivity (MCS), outlines the concepts and evidence for the olfactory-limbic, neural sensitization model for MCS, and discusses experimental design implications of the model for exposure-related research. Neural sensitization is the progressive am...

journal_title：Environmental health perspectives

authors： Bell IR,Schwartz GE,Baldwin CM,Hardin EE,Klimas NG,Kline JP,Patarca R,Song ZY

更新日期：1997-03-01 00:00:00

abstract：:This paper examines behavioral changes in natural populations of wildlife associated with pollution. Although some changes such as lack of nest attentiveness and decreased nest defense have been noted, the results have not been consistent and have been difficult to relate to specific pollutants. Experimental studies i...

journal_title：Environmental health perspectives

authors： Peakall DB

更新日期：1996-04-01 00:00:00

abstract：:Human biomonitoring investigations have provided data on a wide array of chemicals in blood and urine and in other tissues and fluids such as hair and human milk. These data have prompted questions such as a) What is the relationship between levels of environmental chemicals in humans and external exposures? b) What i...

journal_title：Environmental health perspectives

authors： Bates MN,Hamilton JW,LaKind JS,Langenberg P,O'Malley M,Snodgrass W

更新日期：2005-11-01 00:00:00

abstract：:The toxicity of cadmium is determined by chelation reactions: in vivo, Cd2+ exists exclusively in coordination complexes with biological ligands, or with administered chelating agents. The Cd2+ ion has some soft character, but it is not a typical soft ion. It has a high degree of polarizability, and its complexes with...

journal_title：Environmental health perspectives

authors： Andersen O

更新日期：1984-03-01 00:00:00

abstract：:We present a model to plan a rational strategy for cancer prevention that has two main functions--assessment and intervention. The assessment function includes three main components: to identify populations at high cancer risk, which may be due to their ethnic group, occupational and environmental exposures, family hi...

journal_title：Environmental health perspectives

authors： Anton-Culver H

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Exposure of the U.S. population to polybrominated diphenyl ethers (PBDEs) is thought to be via exposure to dust and diet. However, little work has been done to empirically link body burdens of these compounds to either route of exposure. OBJECTIVES:The primary goal of this research was to evaluate the dieta...

journal_title：Environmental health perspectives

authors： Fraser AJ,Webster TF,McClean MD

更新日期：2009-10-01 00:00:00