Mechanisms associated with human alveolar macrophage stimulation by particulates.

abstract：:The potential danger of natural mercury accumulation in the diet of the Eskimo is evaluated through mercury levels determined in cord blood, placenta, maternal blood, hair, and milk of 38 maternal-infant pairs from Anchorage and the Yukon-Kuskokwim Delta. Although mercury levels are not discernably dangerous, trends t...

journal_title：Environmental health perspectives

authors： Galster WA

更新日期：1976-06-01 00:00:00

abstract：:For decades, a number of guinea pig tests have been used to identify human contact allergens in workplace and consumer products, but these tests have limitations. In addition to using large numbers of test animals, they also provide only subjective measurements, because the allergic activity is measured by watching th...

journal_title：Environmental health perspectives

authors： Clay R

更新日期：1998-10-01 00:00:00

abstract：:This paper reports on the prevalence of lead poisoning in children between 1 and 5 years of age living in a marginal area to the north of Mexico City and also includes an evaluation of sources of exposure to this metal in the same area. The results show that 67.5% of the children studied have blood lead (PbB) levels >...

journal_title：Environmental health perspectives

authors： López-Carrillo L,Torres-Sánchez L,Garrido F,Papaqui-Hernández J,Palazuelos-Rendón E,López-Cervantes M

更新日期：1996-11-01 00:00:00

abstract：:The decline of many amphibian species could be caused by their susceptibility to environmental pollutants that cause cellular stress and cell death. A variety of intracellular signal transduction pathways are activated by environmental stress factors, which result in cell death. Mitogen-activated protein kinases are i...

journal_title：Environmental health perspectives

authors： Carter LA,Tabor MB,Bonner JC,Bonner LA

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS:We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at ter...

journal_title：Environmental health perspectives

authors： Lederman SA,Jones RL,Caldwell KL,Rauh V,Sheets SE,Tang D,Viswanathan S,Becker M,Stein JL,Wang RY,Perera FP

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Adverse cardiorespiratory health is associated with exposure to ambient particulate matter (PM). The highest PM concentrations in London occur in proximity to waste transfer stations (WTS), sites that experience high numbers of dust-laden, heavy-duty diesel vehicles transporting industrial and household wast...

journal_title：Environmental health perspectives

authors： Godri KJ,Duggan ST,Fuller GW,Baker T,Green D,Kelly FJ,Mudway IS

更新日期：2010-04-01 00:00:00

abstract：:The combination of cigarette smoke and high-level occupational asbestos exposure produces a synergistic increase in the incidence of lung cancer; however, smoking does not affect the incidence of mesothelioma. Here we present the results of tests of two theories that have been proposed to explain this phenomenon; name...

journal_title：Environmental health perspectives

authors： Sekhon HS,Keeling B,Churg A

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested an effect of high arsenic concentration on cognitive and neurobehavioral function in humans. OBJECTIVE:Our goal was to identify demographic and nutritional factors that are associated with As exposure and the influence of this exposure on cognitive function in school-age chil...

journal_title：Environmental health perspectives

authors： Rosado JL,Ronquillo D,Kordas K,Rojas O,Alatorre J,Lopez P,Garcia-Vargas G,Del Carmen Caamaño M,Cebrián ME,Stoltzfus RJ

更新日期：2007-09-01 00:00:00

abstract：:In different weather conditions, constituents and concentrations of pollutants, personal exposure, and biologic responses to air pollution may vary. In this study we assessed the effects of four air pollutants on mortality in both cool and warm seasons in Hong Kong, a subtropical city. Daily counts of mortality, due t...

journal_title：Environmental health perspectives

authors： Wong CM,Ma S,Hedley AJ,Lam TH

更新日期：2001-04-01 00:00:00

abstract：:Because of its unique geology, Minnesota can be divided into four agricultural regions: south-central region one (corn, soybeans); west-central region two (wheat, corn, soybeans); northwest region three (wheat, sugar beets, potatoes); and northeast region four (forested and urban in character). Cancer mortality (1980-...

journal_title：Environmental health perspectives

authors： Schreinemachers DM,Creason JP,Garry VF

更新日期：1999-03-01 00:00:00

abstract：:Millions of people worldwide are exposed to arsenic-contaminated drinking water, and ingestion of inorganic arsenic (InAs) has been associated with increased risks of cancer. The primary metabolic pathway of ingested InAs is methylation to monomethyl arsenic (MMA) and dimethyl arsenic (DMA). However, people vary great...

journal_title：Environmental health perspectives

authors： Steinmaus C,Carrigan K,Kalman D,Atallah R,Yuan Y,Smith AH

更新日期：2005-09-01 00:00:00

abstract：:Perchlorate (ClO4-) has been detected in groundwater sources in numerous communities in California and other parts of the United States, raising concerns about potential impacts on health. For California communities where ClO4- was tested in 1997 and 1998, we evaluated the prevalence of primary congenital hypothyroidi...

journal_title：Environmental health perspectives

authors： Buffler PA,Kelsh MA,Lau EC,Edinboro CH,Barnard JC,Rutherford GW,Daaboul JJ,Palmer L,Lorey FW

更新日期：2006-05-01 00:00:00

abstract：:The remarkable frequency of uterine leiomyoma in the human population calls into question the potential for the participation of environmental factors in tumor etiology. Having been implicated in the dramatic rise in hormone-related cancers in recent years, endocrine disruptors are salient suspects in this pathogenesi...

journal_title：Environmental health perspectives

authors： Hunter DS,Hodges LC,Eagon PK,Vonier PM,Fuchs-Young R,Bergerson JS,Walker CL

更新日期：2000-10-01 00:00:00

abstract：:Determination of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in fly ash and cinders collected from nine municipal incinerators in Japan was made. The concentrations of PCDDs and PCDFs in this study were generally in the same range as those in Europe and North America. However, t...

journal_title：Environmental health perspectives

authors： Wakimoto T,Tatsukawa R

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Bacterial meningitis causes a high burden of disease in the African meningitis belt, with regular seasonal hyperendemicity and sporadic short, but intense, localized epidemics during the late dry season occurring at a small spatial scale [i.e., below the district level, in individual health centers (HCs)]. I...

journal_title：Environmental health perspectives

authors： Woringer M,Martiny N,Porgho S,Bicaba BW,Bar-Hen A,Mueller JE

更新日期：2018-09-01 00:00:00

abstract：:Benzene has been known to be a bone marrow poison for almost a century. However, it was not until the last decade that benzene's carcinogenic potential was demonstrated by epidemiologic studies. The proposed regulation by the Occupational Safety and Health Administration (OSHA) to lower exposure levels of benzene in t...

journal_title：Environmental health perspectives

authors： Infante PF,White MC

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Benzene is a common industrial chemical known to induce leukemia and other blood disorders, as well as aneuploidy, in both human blood cells and sperm at exposures > 10 ppm. Recent reports have identified health effects at exposure levels < 1 ppm, the permissible exposure limit (PEL; 8 hr) set by the U.S. Oc...

journal_title：Environmental health perspectives

authors： Xing C,Marchetti F,Li G,Weldon RH,Kurtovich E,Young S,Schmid TE,Zhang L,Rappaport S,Waidyanatha S,Wyrobek AJ,Eskenazi B

更新日期：2010-06-01 00:00:00

abstract：:Lung counting is highly geometry dependent, especially at low photon energies. Monte Carlo simulations have been used to determine the magnitude of the errors obtained if it is assumed that the deposition is homogeneous, when in fact it is not. Simulation for a germanium lung counting system consisting of four, 70 mm ...

journal_title：Environmental health perspectives

authors： Kramer GH

更新日期：1997-12-01 00:00:00

abstract：:Clinical and experimental studies on respiratory involvement and alterations in immune status were carried out. Respiratory distress occurring in these patients has improved gradually for 14 years but still remains. Copious expectoration at an early stage of the disease may be related to the fact that a number of disc...

journal_title：Environmental health perspectives

authors： Nakanishi Y,Shigematsu N,Kurita Y,Matsuba K,Kanegae H,Ishimaru S,Kawazoe Y

更新日期：1985-02-01 00:00:00

abstract：:Environmental health is a subject that has only relatively recently become prominent in the social consciousness. Even as its significance becomes known, finding ways to integrate the subject into education for primary and secondary students is difficult because of federal testing requirements under the No Child Left ...

journal_title：Environmental health perspectives

authors： Brown VJ

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Organophosphate flame retardants (PFRs) are becoming popular replacements for the phased-out polybrominated diphenyl ether (PBDE) mixtures, and they are now commonly detected in indoor environments. However, little is known about human exposure to PFRs because they cannot be easily measured in blood or serum...

journal_title：Environmental health perspectives

authors： Hoffman K,Garantziotis S,Birnbaum LS,Stapleton HM

更新日期：2015-02-01 00:00:00

abstract：:Ingestion is an important exposure route for polycyclic aromatic hydrocarbons (PAHs) to enter the human body. Although the formation of hazardous PAH metabolites by human biotransformation enzymes is well documented, nothing is known about the PAH transformation potency of human intestinal microbiota. Using a gastroin...

journal_title：Environmental health perspectives

authors： Van de Wiele T,Vanhaecke L,Boeckaert C,Peru K,Headley J,Verstraete W,Siciliano S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:We evaluated the association between drinking-water disinfection by-products and preterm births using improved exposure assessment and more appropriate analysis methods than used in prior studies. METHODS:During 1999-2001, vital record data were obtained for a large, racially diverse population residing in ...

journal_title：Environmental health perspectives

authors： Lewis C,Suffet IH,Hoggatt K,Ritz B

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Cumulative lead exposure is associated with a widened pulse pressure (PP; the -difference between systolic and diastolic blood pressure), a marker of arterial stiffness and a predictor of cardiovascular disease. Polymorphisms in the hemochromatosis gene (HFE) have been shown to modify the impact of cumulativ...

journal_title：Environmental health perspectives

authors： Zhang A,Park SK,Wright RO,Weisskopf MG,Mukherjee B,Nie H,Sparrow D,Hu H

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Drinking water in multiple water districts in the Mid-Ohio Valley has been contaminated with perfluorooctanoic acid (PFOA), which was released by a nearby DuPont chemical plant. Two highly contaminated water districts began granular activated carbon filtration in 2007. OBJECTIVES:To determine the rate of de...

journal_title：Environmental health perspectives

authors： Bartell SM,Calafat AM,Lyu C,Kato K,Ryan PB,Steenland K

更新日期：2010-02-01 00:00:00

abstract：:Phthalates are a group of multifunctional chemicals used in consumer and personal care products, plastics, and medical devices. Laboratory studies show that some phthalates are reproductive and developmental toxicants. Recently, human studies have shown measurable levels of several phthalates in most of the U.S. gener...

journal_title：Environmental health perspectives

authors： Hauser R,Duty S,Godfrey-Bailey L,Calafat AM

更新日期：2004-05-01 00:00:00

abstract：:Diffuse pulmonary fibrosis is associated with bleomycin administration to humans. The sequential reactions of lung cells to this drug have now been investigated in mice following injection of 20 mg/kg bleomycin twice per week for 4 to 8 weeks. Cytoplasmic and subendothelial edema was first observed in large vessels an...

journal_title：Environmental health perspectives

authors： Adamson IY

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Arsenicals (roxarsone and nitarsone) used in poultry production likely increase inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and roxarsone or nitarsone concentrations in poultry meat. However, the association between poultry intake and exposure to these arsenic species, ...

journal_title：Environmental health perspectives

authors： Nigra AE,Nachman KE,Love DC,Grau-Perez M,Navas-Acien A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:We have previously shown that adult male mice exposure to low doses of an ubiquitous endocrine disruptor, di(2-ethylhexyl) phthalate (DEHP), alters courtship behavior. OBJECTIVE:The effects of adult exposure to low doses of DEHP alone or in an environmental phthalate mixture on estrous cyclicity, reproducti...

journal_title：Environmental health perspectives

authors： Adam N,Brusamonti L,Mhaouty-Kodja S

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Polybrominated diphenyl ethers (PBDEs) are flame retardants found in North American household products during the past four decades. These chemicals leach out in dust as products age, exposing individuals daily through inhalation and ingestion. Animal studies suggest that PBDEs disrupt sex hormones and adver...

journal_title：Environmental health perspectives

authors： Goodyer CG,Poon S,Aleksa K,Hou L,Atehortua V,Carnevale A,Koren G,Jednak R,Emil S,Bagli D,Dave S,Hales BF,Chevrier J

更新日期：2017-05-26 00:00:00