Abstract：
:The presence of blue-green algae (BGA) toxins in surface waters used for drinking water sources and recreation is receiving increasing attention around the world as a public health concern. However, potential risks from exposure to these toxins in contaminated health food products that contain BGA have been largely ignored. BGA products are commonly consumed in the United States, Canada, and Europe for their putative beneficial effects, including increased energy and elevated mood. Many of these products contain Aphanizomenon flos-aquae, a BGA that is harvested from Upper Klamath Lake (UKL) in southern Oregon, where the growth of a toxic BGA, Microcystis aeruginosa, is a regular occurrence. M. aeruginosa produces compounds called microcystins, which are potent hepatotoxins and probable tumor promoters. Because M. aeruginosa coexists with A. flos-aquae, it can be collected inadvertently during the harvesting process, resulting in microcystin contamination of BGA products. In fall 1996, the Oregon Health Division learned that UKL was experiencing an extensive M. aeruginosa bloom, and an advisory was issued recommending against water contact. The advisory prompted calls from consumers of BGA products, who expressed concern about possible contamination of these products with microcystins. In response, the Oregon Health Division and the Oregon Department of Agriculture established a regulatory limit of 1 microg/g for microcystins in BGA-containing products and tested BGA products for the presence of microcystins. Microcystins were detected in 85 of 87 samples tested, with 63 samples (72%) containing concentrations > 1 microg/g. HPLC and ELISA tentatively identified microcystin-LR, the most toxic microcystin variant, as the predominant congener.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
Gilroy DJ,Kauffman KW,Hall RA,Huang X,Chu FSdoi
10.1289/ehp.00108435subject
Has Abstractpub_date
2000-05-01 00:00:00pages
435-9issue
5eissn
0091-6765issn
1552-9924pii
sc271_5_1835journal_volume
108pub_type
杂志文章abstract：BACKGROUND:Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region. OBJECTIVES:We aimed to elucidate the association between environmental and infectious exposures and cirrhosis in...
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journal_title：Environmental health perspectives
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更新日期：2008-05-01 00:00:00
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更新日期：1998-04-01 00:00:00
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更新日期：2002-05-01 00:00:00
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更新日期：1985-09-01 00:00:00
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更新日期：2012-03-01 00:00:00
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doi：10.1289/ehp.78231
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更新日期：2007-05-01 00:00:00
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更新日期：2006-12-01 00:00:00
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更新日期：2006-04-01 00:00:00
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更新日期：2021-01-01 00:00:00
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更新日期：1994-10-01 00:00:00
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