Maternal exposure to a brominated flame retardant and genitourinary conditions in male offspring.

abstract：:The activities of plants and plant/microbial associations may offer a viable means of accomplishing the in situ remediation of contaminated soils. Two uses of plants for phytoremediation are reported here. In one set of studies, the ability of plants to foster degradative microorganisms was investigated. Results indic...

journal_title：Environmental health perspectives

authors： Shann JR

更新日期：1995-06-01 00:00:00

abstract：:The available data on the influence of selenium on the toxicity of methylmercury and of methylmercury on selenium as a nutrient and toxic agent are reviewed. Selenium as selenite has a relative protective effect on acute and subacute toxicity of methylmercury in the rat and the quail. The protective mechanism is far f...

journal_title：Environmental health perspectives

authors： Skerfving S

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Most studies on endocrine-disrupting chemicals and breast cancer have focused on single compounds and have produced inconclusive findings. OBJECTIVES:We assessed the combined estrogenic effects of mixtures of xenoestrogens in serum and their relationship to breast cancer risk. METHODS:A total of 186 incide...

journal_title：Environmental health perspectives

authors： Pastor-Barriuso R,Fernández MF,Castaño-Vinyals G,Whelan D,Pérez-Gómez B,Llorca J,Villanueva CM,Guevara M,Molina-Molina JM,Artacho-Cordón F,Barriuso-Lapresa L,Tusquets I,Dierssen-Sotos T,Aragonés N,Olea N,Kogevinas M,Pollá

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Dozens of studies link acute exposure to particulate matter (PM) air pollution with premature mortality and morbidity, but questions remain about which species and sources in the vast PM mixture are responsible for the observed health effects. Although a few studies exist on the effects of species and source...

journal_title：Environmental health perspectives

authors： Ostro B,Tobias A,Querol X,Alastuey A,Amato F,Pey J,Pérez N,Sunyer J

更新日期：2011-12-01 00:00:00

abstract：:In vitro liver preparations are increasingly used for the study of hepatotoxicity of chemicals. In recent years their actual advantages and limitations have been better defined. The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions...

journal_title：Environmental health perspectives

authors： Guillouzo A

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Tungsten carbide nanoparticles are being explored for their use in the manufacture of hard metals. To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. OBJECTIVE:We aimed to assess the toxicity of well-characte...

journal_title：Environmental health perspectives

authors： Bastian S,Busch W,Kühnel D,Springer A,Meissner T,Holke R,Scholz S,Iwe M,Pompe W,Gelinsky M,Potthoff A,Richter V,Ikonomidou C,Schirmer K

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Glycol ethers (GE) are widely used organic solvents. Despite the potential neurotoxicity of several families of organic solvents, little is known about the impact of GE on the neurodevelopment of infants and children. OBJECTIVES:We investigated the relation between urinary concentrations of GE metabolites i...

journal_title：Environmental health perspectives

authors： Béranger R,Garlantézec R,Le Maner-Idrissi G,Lacroix A,Rouget F,Trowbridge J,Warembourg C,Monfort C,Le Gléau F,Jourdin M,Multigner L,Cordier S,Chevrier C

更新日期：2017-04-01 00:00:00

abstract：:We review pharmacokinetic and pharmacodynamic factors that should be considered in the design and interpretation of developmental neurotoxicity studies. Toxicologic effects on the developing nervous system depend on the delivered dose, exposure duration, and developmental stage at which exposure occurred. Several phar...

journal_title：Environmental health perspectives

authors： Dorman DC,Allen SL,Byczkowski JZ,Claudio L,Fisher JE Jr,Fisher JW,Harry GJ,Li AA,Makris SL,Padilla S,Sultatos LG,Mileson BE

更新日期：2001-03-01 00:00:00

abstract：:A series of experiments is described in which operant methodology is used to study the effects of drugs on "learning." Emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state. In this technique, each subject is required to learn a new discriminati...

journal_title：Environmental health perspectives

authors： Thompson DM,Moerschbaecher JM

更新日期：1978-10-01 00:00:00

abstract：:This article briefly summarizes the epidemiology of the health effects of fine particulate air pollution, provides an early, somewhat speculative, discussion of the contribution of epidemiology to evaluating biologic mechanisms, and evaluates who's at risk or is susceptible to adverse health effects. Based on prelimin...

journal_title：Environmental health perspectives

authors： Pope CA 3rd

更新日期：2000-08-01 00:00:00

abstract：:Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes. However, the integration of genomic information with toxicology will enhance our basic understanding of these processes and significantly change the way we apply toxicological information to ris...

journal_title：Environmental health perspectives

authors： Thomas RS,Rank DR,Penn SG,Zastrow GM,Hayes KR,Hu T,Pande K,Lewis M,Jovanovich SB,Bradfield CA

更新日期：2002-12-01 00:00:00

abstract：:Previous studies in our laboratory demonstrated that high-performance liquid chromatography (HPLC) analysis of ground corncob bedding extracts characterized two components (peak I and peak II) that disrupted endocrine function in male and female rats and stimulated breast and prostate cancer cell proliferation in vitr...

journal_title：Environmental health perspectives

authors： Markaverich BM,Crowley JR,Alejandro MA,Shoulars K,Casajuna N,Mani S,Reyna A,Sharp J

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The autonomic nervous system plays a key role in maintaining homeostasis and responding to external stimuli. In adults, exposure to fine particulate matter ( PM ...

journal_title：Environmental health perspectives

authors： Cowell WJ,Brunst KJ,Malin AJ,Coull BA,Gennings C,Kloog I,Lipton L,Wright RO,Enlow MB,Wright RJ

更新日期：2019-10-01 00:00:00

abstract：:Articles in the literature on alpha-1 antitrypsin (AAT) deficiency have been interpreted as indicating that AAT deficiency is a rare disease that affects mainly Caucasians (whites) from northern Europe. In a recent publication on the worldwide racial and ethnic distribution of AAT deficiency, new data were presented d...

journal_title：Environmental health perspectives

authors： de Serres FJ

更新日期：2003-12-01 00:00:00

abstract：:The populations of the developed nations of the world exhibit an increase in blood pressure with age, while in primitive societies blood pressure remains relatively constant throughout adult life. Hypertension may be a complex of diseases all having the same clinical manifestations but not being caused necessarily by ...

journal_title：Environmental health perspectives

authors： Tuthill RW,Calabrese EJ

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Organophosphate flame retardants (PFRs) are becoming popular replacements for the phased-out polybrominated diphenyl ether (PBDE) mixtures, and they are now commonly detected in indoor environments. However, little is known about human exposure to PFRs because they cannot be easily measured in blood or serum...

journal_title：Environmental health perspectives

authors： Hoffman K,Garantziotis S,Birnbaum LS,Stapleton HM

更新日期：2015-02-01 00:00:00

abstract：:The knowledge of specific problems of occupational cancer in Spain is scarce. The environment of the workplace has improved over the last few years after a long period distinguished by bad working conditions, incomplete legislation, and insufficient safety measures and control. It has been estimated that 3,083,479 wor...

journal_title：Environmental health perspectives

authors： González CA,Agudo A

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Perfluoroalkyl acids are persistent compounds used in various industrial -applications. Of these compounds, perfluorooctanoate (PFOA) is currently detected in humans worldwide. A recent study on low-dose developmental exposure to PFOA in mice reported increased weight and elevated biomarkers of adiposity in ...

journal_title：Environmental health perspectives

authors： Halldorsson TI,Rytter D,Haug LS,Bech BH,Danielsen I,Becher G,Henriksen TB,Olsen SF

更新日期：2012-05-01 00:00:00

abstract：:Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies demonstrated that male BD IX rats consuming diets containing 50 ppm fumonisin B1 developed hepatocellular carcinomas. In our recent studies, diets containing FB1 at 50 ...

journal_title：Environmental health perspectives

authors： Howard PC,Warbritton A,Voss KA,Lorentzen RJ,Thurman JD,Kovach RM,Bucci TJ

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Chronic exposure to arsenic (As), a human toxicant and carcinogen, remains a global public health problem. Health risks persist after As exposure has ended, suggesting epigenetic dysregulation as a mechanistic link between exposure and health outcomes. OBJECTIVES:We investigated the association between tota...

journal_title：Environmental health perspectives

authors： Bozack AK,Domingo-Relloso A,Haack K,Gamble MV,Tellez-Plaza M,Umans JG,Best LG,Yracheta J,Gribble MO,Cardenas A,Francesconi KA,Goessler W,Tang WY,Fallin MD,Cole SA,Navas-Acien A

更新日期：2020-06-01 00:00:00

abstract：:A comprehensive effort was undertaken to identify articles demonstrating chemical hormesis. Nearly 4000 potentially relevant articles were retrieved from preliminary computer database searches by using various key word descriptors and extensive cross-referencing. A priori evaluation criteria were established including...

journal_title：Environmental health perspectives

authors： Calabrese EJ,Baldwin LA

更新日期：1998-02-01 00:00:00

abstract：:Considerable attention has been given to the relationship between levels of fine particulate matter (particulate matter < or = 2.5 microm in aerodynamic diameter; PM(2.5) in the atmosphere and health effects in human populations. Since the U.S. Environmental Protection Agency began widespread monitoring of PM(2.5) lev...

journal_title：Environmental health perspectives

authors： Holloman CH,Bortnick SM,Morara M,Strauss WJ,Calder CA

更新日期：2004-09-01 00:00:00

abstract：:Aluminum lactate [Al(lact)3] (hydrophilic, hydrolytically unstable) and aluminum acetylacetonate [Al(acae)3] (lipophilic, hydrolytically stable) were tested as potential toxicants to rabbits upon IV administration both as aqueous solutions and as liposome suspensions. Both chemicals behaved as cardiotoxic agents when ...

journal_title：Environmental health perspectives

authors： Bombi GG,Corain B,Favarato M,Giordano R,Nicolini M,Perazzolo M,Tapparo A,Zatta P

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue. OBJECTIVES:We aimed to examine the relationship between environmental cadmium exposure and dental caries in children 6-12 years of age. METHODS:We analyzed c...

journal_title：Environmental health perspectives

authors： Arora M,Weuve J,Schwartz J,Wright RO

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The toxicity of many xenobiotic compounds is believed to involve oxidative injury to cells. Direct assessment of mechanistic events involved in xenobiotic-induced oxidative stress is not easily achievable. Development of genetically encoded probes designed for monitoring intracellular redox changes represent...

journal_title：Environmental health perspectives

authors： Gibbs-Flournoy EA,Simmons SO,Bromberg PA,Dick TP,Samet JM

更新日期：2013-03-01 00:00:00

abstract：:The Thomsen-Friedenreich antigen (Gal-GalNAc) represents a tumor-associated molecule, which is assumed to be one of the few chemically well-defined antigens with a proven association with malignancy. In order to analyze the role of the carbohydrate structure Gal-GalNAc for gastrointestinal tumors, we immunized Balb/c ...

journal_title：Environmental health perspectives

authors： Dippold W,Steinborn A,Meyer zum Büschenfelde KH

更新日期：1990-08-01 00:00:00

abstract：:Recent studies show that young children can be exposed to pesticides during normal oral exploration of their environment and their level of dermal contact with floors and other surfaces. Children living in agricultural areas may be exposed to higher pesticide levels than other children because of pesticides tracked in...

journal_title：Environmental health perspectives

authors： Eskenazi B,Bradman A,Castorina R

更新日期：1999-06-01 00:00:00

abstract：:Carbon monoxide is widely distributed in the environment, and acute or chronic toxic effects may be of considerable public health significance. A review of the basis for current ambient standards is given. Mortality and morbidity studies have been negative or equivocal in relating carbon monoxide levels to health effe...

journal_title：Environmental health perspectives

authors： Kuller LH,Radford EP

更新日期：1983-10-01 00:00:00

abstract：:The Florence Statement on Triclosan and Triclocarban documents a consensus of more than 200 scientists and medical professionals on the hazards of and lack of demonstrated benefit from common uses of triclosan and triclocarban. These chemicals may be used in thousands of personal care and consumer products as well as ...

journal_title：Environmental health perspectives

authors： Halden RU,Lindeman AE,Aiello AE,Andrews D,Arnold WA,Fair P,Fuoco RE,Geer LA,Johnson PI,Lohmann R,McNeill K,Sacks VP,Schettler T,Weber R,Zoeller RT,Blum A

更新日期：2017-06-20 00:00:00

abstract：:Parental occupational exposures might affect childhood cancer in the offspring through genetic changes in the ovum or sperm or through transplacental carcinogenesis. The 24 published epidemiologic studies of this association have all used case-control designs, with controls generally selected from birth certificates o...

journal_title：Environmental health perspectives

authors： Savitz DA,Chen JH

更新日期：1990-08-01 00:00:00