An association between fine particles and asthma emergency department visits for children in Seattle.

Abstract:

:Asthma is the most common chronic illness of childhood and its prevalence is increasing, causing much concern for identification of risk factors such as air pollution. We previously conducted a study showing a relationship between asthma visits in all persons < 65 years of age to emergency departments (EDs) and air pollution in Seattle, Washington. In that study the most frequent zip codes of the visits were in the inner city. The Seattle-King County Department of Public Health (Seattle, WA) subsequently published a report which showed that the hospitalization rate for children in the inner city was over 600/100,000, whereas it was < 100/100,000 for children living in the suburbs. Therefore, we conducted the present study to evaluate whether asthma visits to hospital emergency departments in the inner city of Seattle were associated with outdoor air pollution levels. ED visits to six hospitals for asthma and daily air pollution data were obtained for 15 months during 1995 and 1996. The association between air pollution and childhood ED visits for asthma from the inner city area with high asthma hospitalization rates were compared with those from lower hospital utilization areas. Daily ED counts were regressed against fine particulate matter (PM), carbon monoxide (CO), sulfur dioxide, and nitrogen dioxide using a semiparametric Poisson regression model. Significant associations were found between ED visits for asthma in children and fine PM and CO. A change of 11 microg/m3 in fine PM was associated with a relative rate of 1.15 [95% confidence interval (CI), 1.08-1.23]. There was no stronger association between ED visits for asthma and air pollution in the higher hospital utilization area than in the lower utilization area. These findings were seen when estimated PM2.5 concentrations were below the newly adopted annual National Ambient Air Quality Standard of 15 microg/m3.

authors

Norris G,YoungPong SN,Koenig JQ,Larson TV,Sheppard L,Stout JW

doi

10.1289/ehp.99107489

subject

Has Abstract

pub_date

1999-06-01 00:00:00

pages

489-93

issue

6

eissn

0091-6765

issn

1552-9924

pii

sc271_5_1835

journal_volume

107

pub_type

杂志文章
  • Cancer mortality in U.S. counties with plastics and related industries.

    abstract::Counties in the United States have been identified with chemical establishments whose primary manufacturing processes use vinyl chloride. Site-specific cancer mortality comparisons have revealed an excess of multiple myeloma in males associated with two of the manufacturing categories, synthetic rubber and synthetic f...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.751179

    authors: Mason TJ

    更新日期:1975-06-01 00:00:00

  • Using the micronucleus assay to detect genotoxic effects of metal ions.

    abstract::The lymphocyte micronucleus assay was used to measure the average frequency of micronuclei in a population and thus assess genotoxic effects. Data from 174 persons give an average value of 16.4 +/- 7.3, and a slight age-dependence was observed. To detect combined environmental mutagen injuries the micronucleus assay w...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.101-1521140

    authors: Bérces J,Otos M,Szirmai S,Crane-Uruena C,Köteles GJ

    更新日期:1993-10-01 00:00:00

  • A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study.

    abstract:BACKGROUND:The Consortium Linking Academic and Regulatory Insights on Bisphenol-A (CLARITY-BPA) is a rare collaboration of guideline-compliant (core) studies and academic hypothesis-based studies to assess the effects of bisphenol A (BPA). OBJECTIVES:We aimed to a) determine whether BPA showed effects on the developin...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP6301

    authors: Montévil M,Acevedo N,Schaeberle CM,Bharadwaj M,Fenton SE,Soto AM

    更新日期:2020-05-01 00:00:00

  • Magnetic fields and cancer: animal and cellular evidence--an overview.

    abstract::A few animal studies on the possible carcinogenic effect of magnetic fields have been published. They have been designed to reveal a possible tumor promotion obtained by applying continuous or pulsed alternating fields at flux densities varying between 0.5 microT and 30 mT on mice or rats initiated with different init...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.95103s263

    authors: Holmberg B

    更新日期:1995-03-01 00:00:00

  • Monitoring metal concentrations in tissues and single cells using ultramicrosensors.

    abstract::Intercellular and extracellular metal concentrations were measured using carbon fiber ultramicrosensors plated with mercury or with polymeric porphyrinic p-type semiconductors. Concentrations of unbound nickel and lead ions were studied within individual BC3H-1 myocytes, and H4-11-C3 rat hepatoma cells. Unbound ions a...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.94102s3147

    authors: Malinski T,Grunfeld S,Taha Z,Tomboulian P

    更新日期:1994-09-01 00:00:00

  • Behavioral assessment of visual toxicity.

    abstract::A wide variety of behavioral methods has been employed with animals to assess visual changes induced by drugs or toxicants. The methods range from simple to complex, from broad screening devices to narrowly focused techniques. Their relative advantages for the environmental toxicologist are discussed. Manipulation of ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.782653

    authors: Evans HL

    更新日期:1978-10-01 00:00:00

  • Depression, Mental Distress, and Domestic Conflict among Louisiana Women Exposed to the Deepwater Horizon Oil Spill in the WaTCH Study.

    abstract:BACKGROUND:Psychological sequelae are among the most pronounced effects in populations following exposure to oil spills. Women in particular represent a vulnerable yet influential population but have remained relatively understudied with respect to the Deepwater Horizon oil spill (DHOS). OBJECTIVE:To describe the rela...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP167

    authors: Rung AL,Gaston S,Oral E,Robinson WT,Fontham E,Harrington DJ,Trapido E,Peters ES

    更新日期:2016-09-01 00:00:00

  • Mold and endotoxin levels in the aftermath of Hurricane Katrina: a pilot project of homes in New Orleans undergoing renovation.

    abstract:BACKGROUND:After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth. OBJECTIVES:A small demonstration project was conducted November 2005-January 2006 aiming to recommend safe remediation techniques and safe levels of worker protection, and to characterize airborne m...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.9258

    authors: Chew GL,Wilson J,Rabito FA,Grimsley F,Iqbal S,Reponen T,Muilenberg ML,Thorne PS,Dearborn DG,Morley RL

    更新日期:2006-12-01 00:00:00

  • Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border.

    abstract::In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extrac...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.6058

    authors: Arrieta DE,Ontiveros CC,Li WW,Garcia JH,Denison MS,McDonald JD,Burchiel SW,Washburn BS

    更新日期:2003-08-01 00:00:00

  • Climate factors influencing coccidioidomycosis seasonality and outbreaks.

    abstract::Although broad links between climatic factors and coccidioidomycosis have been established, the identification of simple and robust relationships linking climatic controls to seasonal timing and outbreaks of the disease has remained elusive. Using an adaptive data-oriented method for estimating date of exposure, in th...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.7786

    authors: Comrie AC

    更新日期:2005-06-01 00:00:00

  • Epidemiological bases for the current ambient carbon monoxide standards.

    abstract::Carbon monoxide is widely distributed in the environment, and acute or chronic toxic effects may be of considerable public health significance. A review of the basis for current ambient standards is given. Mortality and morbidity studies have been negative or equivocal in relating carbon monoxide levels to health effe...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8352131

    authors: Kuller LH,Radford EP

    更新日期:1983-10-01 00:00:00

  • Mechanisms underlying Children's susceptibility to environmental toxicants.

    abstract::An important public health challenge has been the need to protect children's health. To accomplish this goal, the scientific community needs scientifically based child-specific risk assessment methods. Critical to their development is the need to understand mechanisms underlying children's sensitivity to environmental...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.00108s113

    authors: Faustman EM,Silbernagel SM,Fenske RA,Burbacher TM,Ponce RA

    更新日期:2000-03-01 00:00:00

  • Metabolic activation and lung toxicity: a basis for cell-selective pulmonary damage by foreign chemicals.

    abstract::The lungs may be exposed to potentially toxic metabolites that are either formed in situ or which are present in the circulation. Therefore, pulmonary injury may be a prominent effect of certain classes of chemicals that undergo bioactivation in the body. The specific types of lung cells damaged may depend upon factor...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.845547

    authors: Boyd MR

    更新日期:1984-04-01 00:00:00

  • Discriminating different classes of toxicants by transcript profiling.

    abstract::Male rats were treated with various model compounds or the appropriate vehicle controls. Most substances were either well-known hepatotoxicants or showed hepatotoxicity during preclinical testing. The aim of the present study was to determine if biological samples from rats treated with various compounds can be classi...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/txg.7036

    authors: Steiner G,Suter L,Boess F,Gasser R,de Vera MC,Albertini S,Ruepp S

    更新日期:2004-08-01 00:00:00

  • Overview of inhalation toxicology.

    abstract::The development of inhalation toxicology as a distinct discipline can be traced back well over one hundred years. The technology has advanced in terms of materials and designs used to construct inhalation chambers and the equipment used to generate controlled test atmospheres of a wide variety of gases, vapors, dusts,...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.85-1568347

    authors: Dorato MA

    更新日期:1990-04-01 00:00:00

  • Evaluation criteria for publishing in top-tier journals in environmental health sciences and toxicology.

    abstract:BACKGROUND:Trying to publish a paper in a top-rated peer-reviewed journal can be a difficult and frustrating experience for authors. It is important that authors understand the general review process before submitting manuscripts for publication. OBJECTIVES:Editors-in-chief and associate editors from top-tier journals...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1003280

    authors: Lee BM

    更新日期:2011-07-01 00:00:00

  • The risk of childhood cancer from intrauterine and preconceptional exposure to ionizing radiation.

    abstract::The findings of studies investigating whether exposures to ionizing radiation before birth, either pre- or post-conception, increase the risk of childhood cancer have provoked much scientific controversy. An epidemiological association between the abdominal exposure of pregnant women to diagnostic X-rays and childhood...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.951031018

    authors: Wakeford R

    更新日期:1995-11-01 00:00:00

  • Dioxins and endometriosis: a plausible hypothesis.

    abstract::A potential connection exists between exposure to organochlorine chemicals and the increasing prevalence of endometriosis. Evidence shows that dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) can increase the incidence and severity of the disease in monkeys and can promote the growth or survival of endometrial tissue impl...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.0211015

    authors: Birnbaum LS,Cummings AM

    更新日期:2002-01-01 00:00:00

  • Biological monitoring of genotoxic hazard in workers of the rubber industry.

    abstract::Biological monitoring of genotoxic hazard in the rubber industry was performed in 19 male workers and 20 age-matched controls in a local health unit in northern Italy. Peripheral blood lymphocytes were analyzed for the presence of DNA damage (single-cell microgel-electrophoresis, or comet assay) and for cytogenetic pa...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.96104s3543

    authors: Moretti M,Villarini M,Scassellati-Sforzolini G,Monarca S,Libraro M,Fatigoni C,Donato F,Leonardis C,Perego L

    更新日期:1996-05-01 00:00:00

  • Toxicogenomics through the eyes of informatics: conference overview and recommendations.

    abstract::Virginia Bioinformatics Institute, in conjunction with National Institutes of Environmental Health Sciences, hosted a conference, "Toxicogenomics through the Eyes of Informatics," in Bethesda, Maryland, USA, on 12-13 May 2003. Researchers around the world met to discuss how the application of bioinformatics tools, met...

    journal_title:Environmental health perspectives

    pub_type:

    doi:10.1289/ehp.112-1241996

    authors: Olden K,Call N,Sobral B,Oakes R

    更新日期:2004-05-01 00:00:00

  • Consumption of PCB-contaminated sport fish and risk of spontaneous fetal death.

    abstract::Spontaneous fetal death has been observed among various mammalian species after exposure to polychlorinated biphenyls (PCBs). Our exposure-based cohort study assessed the relationship between consumption of PCB-contaminated Lake Ontario sport fish and spontaneous fetal death using 1820 multigravid fertile women from t...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.95103498

    authors: Mendola P,Buck GM,Vena JE,Zielezny M,Sever LE

    更新日期:1995-05-01 00:00:00

  • The use of ferrokinetics in the study of experimental anemia.

    abstract::Erythropoietic cells in bone marrow are vulnerable to cytotoxic substances. There are three types of erythroid precursors: cells that can take up Fe but do not proliferate (reticulocytes), those that can take up Fe and proliferate (normoblasts and pronormoblasts), and those cells that do not take up Fe but can prolife...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.813929

    authors: Lee EW,Kocsis JJ,Snyder R

    更新日期:1981-06-01 00:00:00

  • Plasma Concentrations of Per- and Polyfluoroalkyl Substances at Baseline and Associations with Glycemic Indicators and Diabetes Incidence among High-Risk Adults in the Diabetes Prevention Program Trial.

    abstract:BACKGROUND:Several per- and polyfluoroalkyl substances (PFAS) are ubiquitous anthropogenic pollutants almost universally detected in humans. Experimental evidence indicates that PFAS alter glucose metabolism and insulin secretion. However, epidemiological studies have yielded inconsistent results. OBJECTIVE:We sought ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,随机对照试验

    doi:10.1289/EHP1612

    authors: Cardenas A,Gold DR,Hauser R,Kleinman KP,Hivert MF,Calafat AM,Ye X,Webster TF,Horton ES,Oken E

    更新日期:2017-10-02 00:00:00

  • Land application of treated sewage sludge: community health and environmental justice.

    abstract:BACKGROUND:In the United States, most of the treated sewage sludge (biosolids) is applied to farmland as a soil amendment. Critics suggest that rules regulating sewage sludge treatment and land application may be insufficient to protect public health and the environment. Neighbors of land application sites report illne...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1205470

    authors: Lowman A,McDonald MA,Wing S,Muhammad N

    更新日期:2013-05-01 00:00:00

  • The effect of heat waves on mental health in a temperate Australian city.

    abstract:OBJECTIVE:The goal of this study was to identify mental, behavioral, and cognitive disorders that may be triggered or exacerbated during heat waves, predisposing individuals to heat-related morbidity and mortality. DESIGN:Using health outcome data from Adelaide, South Australia, for 1993-2006, we estimated the effect ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.11339

    authors: Hansen A,Bi P,Nitschke M,Ryan P,Pisaniello D,Tucker G

    更新日期:2008-10-01 00:00:00

  • State monitoring activities related to Pfiesteria-like organisms.

    abstract::In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland dur...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.01109s5711

    authors: Magnien RE

    更新日期:2001-10-01 00:00:00

  • Juvenile hypothyroidism among two populations exposed to radioiodine.

    abstract::We found an epidemic of juvenile hypothyroidism among a population of self-defined "downwinders" living near the Hanford nuclear facility located in southeast Washington State. The episode followed massive releases of 131I. Self-reported data on 60 cases of juvenile hypothyroidism (<20 years of age) among a group of 8...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.99107303

    authors: Goldsmith JR,Grossman CM,Morton WE,Nussbaum RH,Kordysh EA,Quastel MR,Sobel RB,Nussbaum FD

    更新日期:1999-04-01 00:00:00

  • Rat pleural mesothelial cells show damage after exposure to external but not internal cigarette smoke.

    abstract::The combination of cigarette smoke and high-level occupational asbestos exposure produces a synergistic increase in the incidence of lung cancer; however, smoking does not affect the incidence of mesothelioma. Here we present the results of tests of two theories that have been proposed to explain this phenomenon; name...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.93101326

    authors: Sekhon HS,Keeling B,Churg A

    更新日期:1993-09-01 00:00:00

  • Maternal smoking during pregnancy and the prevalence of autism spectrum disorders, using data from the autism and developmental disabilities monitoring network.

    abstract:BACKGROUND:Reported associations between gestational tobacco exposure and autism spectrum disorders (ASDs) have been inconsistent. OBJECTIVE:We estimated the association between maternal smoking during pregnancy and ASDs among children 8 years of age. METHODS:This population-based case-cohort study included 633,989 c...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1104556

    authors: Kalkbrenner AE,Braun JM,Durkin MS,Maenner MJ,Cunniff C,Lee LC,Pettygrove S,Nicholas JS,Daniels JL

    更新日期:2012-07-01 00:00:00

  • Cell proliferation in the liver and thyroid of C57Bl/10J mice after dietary administration of chlordane.

    abstract::Chlordane is a polychlorinated hydrocarbon that causes liver enlargement and induces mixed-function oxidases similar to those induced by phenobarbitone in the mouse. We have assessed the hepatocarcinogenicity (after 2 years) and the time course (over 6 months) of liver and thyroid cell proliferation in C57Bl/10J mice ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.93101s5219

    authors: Barrass N,Stewart M,Warburton S,Aitchison J,Jackson D,Wadsworth P,Marsden A,Orton T

    更新日期:1993-12-01 00:00:00