Abstract:
:The water extract of Biota orientalis showed a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets using [3H]PAF as a ligand in our previous screening studies for Korean medicinal antagonists by the activity-guided purification studies. Another active compound, compound 1 (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 micrograms/ml, n = 4) was isolated from the title plant. The chemical structure of compound 1 was elucidated as pinusolidic acid by chemical and spectrometric analyses.
journal_name
Planta Medjournal_title
Planta medicaauthors
Yang HO,Han BHsubject
Has Abstractpub_date
1998-02-01 00:00:00pages
72-4issue
1eissn
0032-0943issn
1439-0221journal_volume
64pub_type
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