Abstract:
:We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estimation of salivary flow, which uses a filter paper for diagnosing dry mouth. Disturbed salivary secretion was observed in 84 (58.3 %) of the 144 patients. In the case of patients free of Sjögren's syndrome, the prevalence of disturbed salivary secretion differed significantly among the disease groups (P < 0.05), with the prevalence being over 50 % in all disease groups other than the rheumatoid arthritis group and the highest in the systemic sclerosis group. There was significant positive correlation between the number of colored spots and oral visual analog scale score (r = 0.45, P < 0.0001). Autoimmune diseases can be accompanied by salivary gland dysfunction, regardless of the presence/absence of complication by Sjögren's syndrome. In the present study, the screening technique for estimation of salivary flow, which uses a filter paper for diagnosing dry mouth, was shown to be a useful means of detecting salivary gland dysfunction.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Maeshima E,Furukawa K,Maeshima S,Koshiba H,Sakamoto Wdoi
10.1007/s00296-012-2611-1subject
Has Abstractpub_date
2013-12-01 00:00:00pages
3079-82issue
12eissn
0172-8172issn
1437-160Xjournal_volume
33pub_type
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journal_title:Rheumatology international
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1007/s00296-003-0421-1
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pub_type: 评论,信件
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1007/s00296-011-1809-y
更新日期:2012-04-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2008-10-01 00:00:00
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journal_title:Rheumatology international
pub_type: 临床试验,杂志文章,评审
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2002-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,meta分析
doi:10.1007/BF00290280
更新日期:1993-01-01 00:00:00