Etodolac: efficacy in osteoarthritis and effects on chondrocyte function.

abstract：:We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...

journal_title：Rheumatology international

authors： Andersen T,Rasmussen TK,Hvid M,Holm CK,Madsen KJ,Jurik AG,Hokland M,Stengaard-Pedersen K,Schiøttz-Christensen B,Deleuran B

更新日期：2012-02-01 00:00:00

abstract：:PXK was identified as a novel candidate gene for systemic lupus erythematosus (SLE) from genome-wide association studies (GWAS) in Caucasians. But a recent replication study in Hong Kong Chinese reported that PXK was not associated with SLE. The aim of this study was to determine whether PXK is associated with SLE in ...

journal_title：Rheumatology international

authors： Kim EM,Bang SY,Kim I,Shin HD,Park BL,Lee HS,Bae SC

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to explore whether the catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with susceptibility to fibromyalgia and fibromyalgia impact questionnaire (FIQ) score in fibromyalgia patients. We conducted a meta-analysis of the associations of the COMT Val158Met polymorphism w...

journal_title：Rheumatology international

authors： Lee YH,Kim JH,Song GG

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and tolerability of long-term treatment with cyclosporin A (CsA) in patients with psoriatic arthritis (PsA). METHODS:Sixty patients with PsA were enrolled in a prospective, nonrandomised study of CsA. Patients with hypertension or hypercreatinemia were exclu...

journal_title：Rheumatology international

authors： Sarzi-Puttini P,Cazzola M,Panni B,Turiel M,Fiorini T,Belai-Beyene N,Chèrié-Lignièré EL

更新日期：2002-04-01 00:00:00

abstract：:Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...

journal_title：Rheumatology international

authors： Onur O,Akinci AS,Akbiyik F,Unsal I

更新日期：2001-05-01 00:00:00

abstract：:Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, are associated with an increased risk of coronary artery disease (CAD) as a result of accelerated atherosclerosis. However, the data on CAD risk of polymyalgia rheumatica (PMR), one of the most common chronic inflamm...

journal_title：Rheumatology international

authors： Ungprasert P,Koster MJ,Warrington KJ,Matteson EL

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to analyze the change of serum chemokins levels of CXCL16, CX3CL1/Fractalkine, and CXCL10/interferon-gamma inducible protein-10 (IP-10) with rheumatoid arthritis (RA), by infliximab treatment. The effects of infliximab treatment were studied in 23 patients with RA, over a period of 30 weeks. ...

journal_title：Rheumatology international

authors： Kageyama Y,Torikai E,Nagano A

更新日期：2007-03-01 00:00:00

abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...

journal_title：Rheumatology international

authors： Thapa R,Chakrabartty S

更新日期：2009-07-01 00:00:00

abstract：:The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with avai...

journal_title：Rheumatology international

authors： Fellous S,Rkain H,Ahid S,Abouqal R,Tahiri L,Hmamouchi I,Achemlal L,El Bouchti I,El Maghraoui A,Ghozlani I,Hassikou H,Harzy T,Ichchou L,Mkinsi O,Niamane R,Bahiri R,Allali F

更新日期：2021-01-02 00:00:00

abstract：:Among the clinical manifestations of systemic lupus erythematosus is an arthropathy, which is usually non-erosive. In many cases, the joint involvement is mild. A subset of patients has deforming, non-erosive Jaccoud's arthropathy, and a minority have an arthropathy with clinical findings similar to rheumatoid arthrit...

journal_title：Rheumatology international

authors： Pipili C,Sfritzeri A,Cholongitas E

更新日期：2009-08-01 00:00:00

abstract：:This study was performed to evaluate the effects of the TNF-alpha inhibitor etanercept on oxidation stress markers representing DNA damage, lipid peroxidation, and protein glycosylation. Twenty-two rheumatoid arthritis (RA) patients underwent etanercept treatment. The levels of serum total, urinary total, and urinary ...

journal_title：Rheumatology international

authors： Kageyama Y,Takahashi M,Nagafusa T,Torikai E,Nagano A

更新日期：2008-01-01 00:00:00

abstract：:The aim of this study was to evaluate whether cyclosporin A (CsA) influences the radiological disease progression in early rheumatoid arthritis (RA) patients in comparison with other disease-modifying drugs (DMARDs). A total of 103 early RA patients, without prior use of DMARDs, were randomized to receive CsA (3 mg/kg...

journal_title：Rheumatology international

authors： Drosos AA,Voulgari PV,Katsaraki A,Zikou AK

更新日期：2000-01-01 00:00:00

abstract：:Methotrexate (MTX) can be toxic to patients suffering from end stage renal disease (ESRD) on hemodialysis even at low doses. This increase in toxicity is more notable in terms of bone marrow suppression in the form of pancytopenia. Many methods of elimination including dialysis itself have been proven ineffective, and...

journal_title：Rheumatology international

authors： Al-Hasani H,Roussou E

更新日期：2011-12-01 00:00:00

abstract：:To date, numerous genetic and epigenetic studies have been performed and provided a crucial step forward in our understanding of the pathogenesis of rheumatic diseases. However, most of the recent advances in the treatment of rheumatic diseases including biological therapies are not based on or even discrepant from th...

journal_title：Rheumatology international

authors： Kato M,Yasuda S,Atsumi T

更新日期：2018-08-01 00:00:00

abstract：:Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA reve...

journal_title：Rheumatology international

authors： Markousis-Mavrogenis G,Nurmohamed MT,Koutsogeorgopoulou L,Dimitroulas T,Katsifis G,Vartela V,Mitsikostas D,Kolovou G,Tektonidou M,Voulgari P,Sfikakis PP,Kitas GD,Mavrogeni SI

更新日期：2020-09-01 00:00:00

abstract：:The aim of this study was to evaluate whether the serum concentration of interleukin-6 (IL-6) reflects disease activity in ankylosing spondylitis (AS). A group of 271 AS patients were enrolled in the study, 261 of whom completed the entire protocol (201 males, 60 females, median age of 53 years). Serum IL-6 was measur...

journal_title：Rheumatology international

authors： Falkenbach A,Herold M

更新日期：1998-01-01 00:00:00

abstract：:Patients with rheumatoid arthritis (RA) have an increased cardiovascular (CV) risk. This study aimed to analyze the effects of Tofacitinib treatment, a Janus kinase inhibitor, on atherosclerosis in patients with RA. Patients with an active RA (28-joint disease activity score-erythrocyte sedimentation rate > 3.2) despi...

journal_title：Rheumatology international

authors： Kume K,Amano K,Yamada S,Kanazawa T,Ohta H,Hatta K,Amano K,Kuwaba N

更新日期：2017-12-01 00:00:00

abstract：:Autoantibodies have been detected in systemic sclerosis patients, and typical clinical features regarding organ involvement by each autoantibody have been reported. To reveal differences in exercise intolerance in patients with either anti-topoisomerase-I or anti-centromere antibodies, 53 systemic sclerosis patients w...

journal_title：Rheumatology international

authors： Someya F,Mugii N,Yahata T,Nakagawa T

更新日期：2013-11-01 00:00:00

abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

journal_title：Rheumatology international

authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

更新日期：2012-07-01 00:00:00

abstract：:Systematic reviews and meta-analyses of randomized trials have long been important synthesis tools for guiding evidence-based medicine. More recently, network meta-analyses, an extension of traditional meta-analyses enabling the comparison of multiple interventions, use new statistical methods to incorporate clinical ...

journal_title：Rheumatology international

authors： Catalá-López F,Tobías A,Cameron C,Moher D,Hutton B

更新日期：2014-11-01 00:00:00

abstract：:We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two g...

journal_title：Rheumatology international

authors： Unal O,Can ME,Ozcan A,Ozcan ME,Erten S,Cagil N

更新日期：2019-06-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune rheumatic disease characterised by vasculopathy, inflammation and fibrosis in multiple organs and occasionally coexists with rheumatic conditions, such as axial spondyloarthritis (axSpA). The aim of this study was to demonstrate the successful use of tofacitinib in SSc and axi...

journal_title：Rheumatology international

authors： Kyriakou A,Parperis K,Nikiphorou E,Psarelis S

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...

journal_title：Rheumatology international

authors： Hasegawa M,Sakai F,Konda N,Okabayashi A,Katsura H,Seto Y

更新日期：2018-06-01 00:00:00

abstract：:CCL28 is a mucosa-associated epithelial-cell-produced chemokine involved in oral defense. We assessed the level of CCL28 in saliva of primary Sjögren's syndrome (pSS) patients in comparison with healthy controls and correlated it with IgA salivary levels. We included 30 non-smoker pSS patients and 30 non-smoker health...

journal_title：Rheumatology international

authors： Hernandez-Molina G,Burkhardt AM,Lima G,Zlotnik A,Betanzos JL,Bahena S,Llorente L

更新日期：2015-08-01 00:00:00

abstract：:The exact elucidation of skeletal and cartilagineous involvement in neonatal-onset multisystem inflammatory disease (NOMID) is still poorly known, and there are few data providing the long-term response to treatment with the available interleukin-1 inhibitors. We present here a 13-year-old boy with NOMID treated with ...

journal_title：Rheumatology international

authors： Rigante D,Leone A,Marrocco R,Laino ME,Stabile A

更新日期：2011-12-01 00:00:00

abstract：:Uveitis may represent an opportunity to diagnose spondyloarthropathies (SpA) earlier and influence treatment decisions. We describe the percentage of acute anterior uveitis (AAU) in a diverse group of SpA patients seen at one academic setting and compare demographic and clinical characteristics according to the presen...

journal_title：Rheumatology international

authors： Gevorgyan O,Riad M,Sarran RD,Merrill PT,Block JA,Castrejon I

更新日期：2019-09-01 00:00:00

abstract：:The aim of this study was to investigate the association of three polymorphisms of CD154 with risk of SLE in Chinese population. The study population comprised 770 Chinese individuals, including 350 SLE patients and 420 healthy controls. The gene polymorphism was measured using Snapshot SNP genotyping assays and confi...

journal_title：Rheumatology international

authors： Xiang Y,Guo J,Peng YF,Huang HT,Lan Y,Wei YS

更新日期：2017-08-01 00:00:00

abstract：:Utilizing monoclonal reagents directed towards antigens of the monocyte-macrophage lineage and Ia antigens, the tissue architecture of synovial membranes obtained from patients with non-inflammatory joint diseases and patients with rheumatoid arthritis was studied. Emphasis was placed on the localization of the type I...

journal_title：Rheumatology international

authors： Burmester GR,Locher P,Koch B,Winchester RJ,Dimitriu-Bona A,Kalden JR,Mohr W

更新日期：1983-01-01 00:00:00

abstract：:The cost-effectiveness of treatments that have the potential to change the "natural history" of a chronic progressive disease has to be evaluated over the long term. Cost-effectiveness estimates have been based on the concept that, with treatment, patients will not progress to the next level(s) of disease severity or ...

journal_title：Rheumatology international

authors： Benucci M,Saviola G,Baiardi P,Manfredi M

更新日期：2011-11-01 00:00:00

abstract：:Balneotherapeutic applications to treat rheumatic diseases have a long-term tradition and are based on established scientific principles, and the majority of rheumatic diseases most frequently include balneotherapy. However, as other therapeutic strategies, balneological interventions require scientific proof of their...

journal_title：Rheumatology international

authors： Lange U,Müller-Ladner U,Schmidt KL

更新日期：2006-04-01 00:00:00