Abstract:
:Balneotherapeutic applications to treat rheumatic diseases have a long-term tradition and are based on established scientific principles, and the majority of rheumatic diseases most frequently include balneotherapy. However, as other therapeutic strategies, balneological interventions require scientific proof of their effect and efficacy. Notably, recent studies providing evidence of the thermic and chemical effects on the immune system and cytokine milieu have enforced the revival of the traditional balneological interventions. This review provides an overview of the known as well as the novel aspects of balneotherapy and their clinical relevance in the treatment of rheumatic diseases.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Lange U,Müller-Ladner U,Schmidt KLdoi
10.1007/s00296-005-0019-xsubject
Has Abstractpub_date
2006-04-01 00:00:00pages
497-9issue
6eissn
0172-8172issn
1437-160Xjournal_volume
26pub_type
杂志文章,评审abstract::The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1519-x
更新日期:2011-12-01 00:00:00
abstract::Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythr...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00272435
更新日期:1988-01-01 00:00:00
abstract::We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2137-y
更新日期:2012-10-01 00:00:00
abstract::Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is exacerbated by pro-inflammatory cytokines signaling. Among the changes triggered in chondrocytes during inflammation, modified expression of tiny epigenetic regulators as microRNAs was shown having deleterious implications for articul...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2754-8
更新日期:2014-05-01 00:00:00
abstract::In this cross-sectional study a comparison was made of rheumatoid factor (RF) isotypes in 203 RF positive patients with arthritis. Of these, 129 had rheumatoid arthritis (RA) and 74 a milder disease that would formerly have been classified as probable RA. The majority (74%) of the RA patients had elevations of two or ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00290265
更新日期:1992-01-01 00:00:00
abstract::Familial Mediterranean fever is characterized by self-limited attacks of serositis and arthritis. However, substantial number of patients suffer from chronic complications of this disease, primarily involving musculoskeletal system. Treatment for these complications is challenging due to limited evidence. Interleukin-...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04490-7
更新日期:2020-01-01 00:00:00
abstract::The objective of the study was to determine the clinical features and treatment course in Canadian patients with dermatomyositis (DM) associated with the anti-melanoma differentiation-associated gene 5 antibody (MDA5). A retrospective chart review of consecutive patients with anti-MDA5 antibody DM from two Canadian te...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04398-2
更新日期:2019-11-01 00:00:00
abstract::Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1877-z
更新日期:2012-08-01 00:00:00
abstract::The aim of this study was to explore whether the catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with susceptibility to fibromyalgia and fibromyalgia impact questionnaire (FIQ) score in fibromyalgia patients. We conducted a meta-analysis of the associations of the COMT Val158Met polymorphism w...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析
doi:10.1007/s00296-014-3075-2
更新日期:2015-01-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic, progressive, debilitating disease that demands continuous therapy with multiple medications. Noncompliance with disease-modifying drugs may cause disease flares, preventable functional impairment, unnecessary treatment changes, and loss of health care resources. The aim of the c...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2162-x
更新日期:2012-10-01 00:00:00
abstract::To evaluate the correlation between measurements of antinuclear antibodies serum levels by enzyme immunoassay (ANA-EIA), and the degree of systemic lupus erythematosus disease activity. To retest the performance of the test compared to measurement of antinuclear antibodies by immunofluorescence (ANA-IIF). Eighty-five ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0324-7
更新日期:2007-08-01 00:00:00
abstract::Sphingolipids are components of the plasma membrane whose metabolic manipulation is of interest as a potential therapeutic approach in a number of diseases. Sphingosine kinase 1 (SphK1), the major kinase that phosphorylates sphingosine to sphingosine-1-phosphate (S1P), was previously shown by our group and others to m...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2493-2
更新日期:2013-10-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disease characterized by the production of autoantibodies against a spectrum of nuclear antigens. RANTES and its receptor CCR5 have been associated with the pathogenesis of SLE. The objective of this study is to analyze autoantibodies (DNA/RNA), al...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2812-2
更新日期:2013-11-01 00:00:00
abstract::The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2639-2
更新日期:2013-07-01 00:00:00
abstract::Knee osteoarthritis is a common disease in the elderly population worldwide. The alleviation of the symptoms associated with this disease can be achieved with physical exercise that induces a cascade of molecular and cellular processes. Of the neurotrophins, brain-derived neurotrophic factor (BDNF) appears to be the m...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2786-0
更新日期:2014-06-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04736-9
更新日期:2021-02-01 00:00:00
abstract::Osteoporosis has become an increasingly recognized complication among patients with chronic liver disease (CLD). The aim of the present study was to assess the prevalence and risk factors of osteoporosis in patients with CLD (primary biliary cirrhosis and chronic viral hepatitis B or C patients) in comparison with a g...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1071-8
更新日期:2010-05-01 00:00:00
abstract::Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002960100105
更新日期:2001-05-01 00:00:00
abstract::Research suggests that health literacy (HL) is associated with rheumatoid arthritis (RA) patients' functional status. Single-item health literacy screening (SILS) questionnaires may establish patients' HL; however, the wording of SILS may be misinterpreted by RA patients as a query regarding physical limitations. Desp...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00296-010-1427-0
更新日期:2011-09-01 00:00:00
abstract::Neurocognitive dysfunction and brain injury on magnetic resonance imaging (MRI) are common in patients with systemic lupus erythematosus (SLE) and are associated with increased morbidity and mortality. However, brain MRI is expensive, is restricted by payers, and requires high expertise. Neurocognitive assessment is a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4080-7
更新日期:2018-08-01 00:00:00
abstract::The results from previous studies on association of IL-6 -174 G/C and -572 G/C polymorphisms with the risk of systemic lupus erythematosus (SLE) remained inconsistent. Therefore, a meta-analysis was performed to assess the association between these two polymorphisms and SLE susceptibility. A literature-based search wa...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00296-013-2855-4
更新日期:2014-02-01 00:00:00
abstract::We aimed to determine left ventricular (LV) and right ventricular (RV) structure, function and mechanics, as well as heart rate variability (HRV), and their relationship, in patients with systemic sclerosis (SSc). The study included 41 SSc patients and 30 age-matched healthy volunteers. All the patients underwent clin...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3618-9
更新日期:2017-01-01 00:00:00
abstract::Currently, many studies have focused on the possibility of using mean platelet volume (MPV) as a biomarker for disease activity in patients with systemic lupus erythematosus (SLE). To derive a more accurate estimation, a meta-analysis was conducted. Embase, PubMed, The Cochrane Library database and several Chinese dat...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析
doi:10.1007/s00296-018-4065-6
更新日期:2018-09-01 00:00:00
abstract::Alkaptonuria is a rare autosomal-recessive disorder that produces accumulation of homogentisic acid in body fluids. The accumulation in collagen tissues, mainly in the joint cartilage, produces ochronotic arthropathy. We report two clinical cases of one brother and sister with alkaptonuria and ochronotic arthropathy d...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-020-04640-2
更新日期:2020-07-08 00:00:00
abstract::Systemic immune defects might reflect severely dysregulated control of chronic inflammation related to disease progression. Th17/Treg cell imbalance has been demonstrated to be involved in rheumatoid arthritis (RA) pathogenesis. Despite controversial results, a growing anti-inflammatory role in this process has been r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2895-9
更新日期:2014-02-01 00:00:00
abstract::Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE) are common systemic autoimmune diseases, which impact not only patient health but also their quality of life. miRNA-146a is a microRNA that participates in the pathophysiology of SjS and SLE. In this investigation, we conducted a meta-analysis to determin...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析
doi:10.1007/s00296-017-3756-8
更新日期:2017-08-01 00:00:00
abstract::Autoantibodies have been detected in systemic sclerosis patients, and typical clinical features regarding organ involvement by each autoantibody have been reported. To reveal differences in exercise intolerance in patients with either anti-topoisomerase-I or anti-centromere antibodies, 53 systemic sclerosis patients w...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2541-y
更新日期:2013-11-01 00:00:00
abstract::Human parvovirus B19 (B19) rarely induces pure red cell aplasia (PRCA) in healthy hosts. Meanwhile B19 infection is often clinically similar to systemic lupus erythematosus (SLE), and several cases have been reported wherein B19 actually stimulated SLE exacerbation in an immunocompetent subject. An 82-year-old healthy...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0227-z
更新日期:2007-02-01 00:00:00
abstract::Anemia is common with connective tissue disorders, but pancytopenia is rare. We report a 22-year-old female who presented with menorrhagia, seizures, anemia, leukocytosis, thrombocytopenia, pericardial effusion, positive ANA, and evidence of vasculitis on CT head scan and was diagnosed with systemic lupus erythematosu...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0318-z
更新日期:2004-01-01 00:00:00