Performance of subjects with knee osteoarthritis during walking: differential parameters.


:The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It also examined the differences in stability and energy consumption between patients with OA and healthy subjects. Fifteen patients with OA and fifteen healthy subjects were recruited into this study. Kinematic and kinetic assessments were performed using Qualysis motion analysis and a force plate Kistler, respectively. Stability of the subjects during walking was determined using COP. Energy consumption was calculated using the Physiological Index. Independent t test was used to determine the differences between gait, stability, and energy consumption healthy participants and patients with knee OA. The excursion of the knee, hip and pelvis in sagittal plane, excursion of the knee joint in the mediolateral plane were significantly higher (all p < 0.05) in patients with OA of the knee compared with their healthy counterparts. In addition, energy consumption was significantly higher in patients with OA (p = 0.009) than in healthy participants. However, margin of stability was significantly lower (p = 0.05) in patients with OA of the knee than in healthy subjects. These findings suggest that gait parameters and energy consumption assessments may be important in patients with OA of the knee. Therefore, clinicians are to be aware of these findings by developing appropriate gait rehabilitation for patients with OA of the knee.


Rheumatol Int


Esrafilian A,Karimi MT,Amiri P,Fatoye F




Has Abstract


2013-07-01 00:00:00












  • Tc-99 m diethylenetriamine-pentaacetic acid (DTPA): is it reliable for assessment of methotrexate-induced cumulative effect on renal filtration in rheumatoid arthritis patients?

    abstract::Methotrexate (MTX) is commonly employed as the initial DMARD used for the treatment of rheumatoid arthritis (RA). We aimed to contribute to the safety profile of MTX by assessing its cumulative effect on renal filtration. A total of 52 RA adult female patients with normal baseline serum creatinine and GFR at the initi...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Amin A,Effat D,Goher N,Ramadan B

    更新日期:2013-12-01 00:00:00

  • Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis.

    abstract::Not all patients with osteoarthritis (OA) show the same disease progression, as some of them remain relatively stable over time, while others progress to severe structural deterioration of the joint. In this sense, the main goal of both genetic and protein biomarkers in OA is to predict not only the risk of OA at an e...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Soto-Hermida A,Fernández-Moreno M,Pértega-Díaz S,Oreiro N,Fernández-López C,Blanco FJ,Rego-Pérez I

    更新日期:2015-02-01 00:00:00

  • Cardiovascular risk in patients with rheumatoid arthritis: assessment of several traditional risk parameters and a German risk score model.

    abstract::The present cross-sectional data demonstrate cardiovascular (CV) risk in patients with rheumatoid arthritis (RA). The cross-sectional data were part of an interventional trial that included 100 patients with defined RA. Traditional CV risk parameters and risk score calculation for the German population were used to as...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Willers J,Hahn A

    更新日期:2012-12-01 00:00:00

  • Determination of inflammation of reflex sympathetic dystrophy at early stages with Tc-99m HIG scintigraphy: preliminary results.

    abstract::The pathogenesis of reflex sympathetic dystrophy (RSD) is not completely understood. However, an excessive regional inflammation, sensitization of primary somatosensory afferents, and sensitization of spinal neurons are considered to have a role in the pathogenesis of RSD. The underlying pathophysiology relating the c...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Okudan B,Celik C

    更新日期:2006-03-01 00:00:00

  • Liver enzyme abnormalities in systemic lupus erythematosus: a focus on toxic hepatitis.

    abstract::Although subclinical liver disease is common in systemic lupus erythematosus (SLE), strikingly high levels of liver enzymes are rare. Our aim was to determine the cause of high levels of liver enzymes in lupus patients, particularly in patients diagnosed with toxic hepatitis. We performed a retrospective chart review ...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Her M,Lee Y,Jung E,Kim T,Kim D

    更新日期:2011-01-01 00:00:00

  • Tocilizumab treatment in Felty's syndrome.

    abstract::Felty's syndrome (FS) is a deforming disease, characterized by the triad of rheumatoid arthritis (RA), neutropenia, and splenomegaly. Currently, FS patients are treated mainly with immunosuppressants, such as methotrexate and glucocorticoids, which however are not suitable to some patients and may cause severe side ef...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Li R,Wan Q,Chen P,Mao S,Wang Q,Li X,Yang Y,Dong L

    更新日期:2020-07-01 00:00:00

  • Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade.

    abstract::The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验


    authors: Rooney T,Edwards CK 3rd,Gogarty M,Greenan L,Veale DJ,FitzGerald O,Dayer JM,Bresnihan B

    更新日期:2010-11-01 00:00:00

  • Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis.

    abstract::This study investigated the prevalence of antibody against annexin II (A2) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). It also explored the role of this antibody in thrombosis. Purified recombinant A2 was used in ELISA to measure the levels of IgG anti-A2 antibody in 101 AP...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Ao W,Zheng H,Chen XW,Shen Y,Yang CD

    更新日期:2011-07-01 00:00:00

  • The effect of interactive digital interventions on physical activity in people with inflammatory arthritis: a systematic review.

    abstract::The aim of this systematic review was to evaluate the evidence from randomised controlled trials (RCTs) evaluating the effectiveness of interactive digital interventions (IDIs) for physical activity (PA) and health related quality of life (HRQoL) in people with Inflammatory Arthritis [rheumatoid arthritis (RA), juveni...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Griffiths AJ,White CM,Thain PK,Bearne LM

    更新日期:2018-09-01 00:00:00

  • Effects of an exercise therapy protocol on inflammatory markers, perception of pain, and physical performance in individuals with knee osteoarthritis.

    abstract::Establishing prevention and therapeutic strategies for osteoarthritis (OA) is necessary to minimize functional disability and the impact of the disease on society. The aim of this study was to determine the effects of an exercise therapy protocol on inflammatory markers, perception of pain, and physical performance in...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Aguiar GC,Do Nascimento MR,De Miranda AS,Rocha NP,Teixeira AL,Scalzo PL

    更新日期:2015-03-01 00:00:00

  • Atypical Kawasaki disease with remarkable paucity of signs and symptoms.

    abstract::We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Thapa R,Chakrabartty S

    更新日期:2009-07-01 00:00:00

  • Hyperleptinemia independent of body adiposity in women with fibromyalgia.

    abstract::The prevalence of overweight and obesity in patients with fibromyalgia is high, which makes these patients more likely to trigger metabolic changes. It is also uncertain whether the clinical manifestations of fibromyalgia alter the metabolism in these patients. This study investigates the influence of adiposity indica...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Homann D,Carvalho HM,Stefanello JM,Góes SM,Lopes AL,de Oliveira AR,Leite N

    更新日期:2014-11-01 00:00:00

  • Comparison of self-report and objective measures of physical activity in US adults with osteoarthritis.

    abstract::To describe levels of daily physical activity and examine the extent of agreement between self-reported and objectively measured indices of physical activity, and characteristics associated with under or overestimated physical activity among persons with osteoarthritis (OA). Using cross-sectional data from the 2003-20...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Liu SH,Eaton CB,Driban JB,McAlindon TE,Lapane KL

    更新日期:2016-10-01 00:00:00

  • Effects of leflunomide and methotrexate in rheumatoid arthritis detected by digital X-ray radiogrammetry and computer-aided joint space analysis.

    abstract::The aim of the present study was to evaluate the effect of long-term leflunomide and methotrexate (MTX) therapy during the course of rheumatoid arthritis (RA) estimated by digital X-ray radiogrammetry (DXR) and computer-aided joint space analysis (CAJSA) as diagnostic tools for the quantification of disease-related pe...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Pfeil A,Lippold J,Eidner T,Lehmann G,Oelzner P,Renz DM,Hansch A,Wolf G,Hein G,Kaiser WA,Böttcher J

    更新日期:2009-01-01 00:00:00

  • Treatment efficacy of etanercept and MTX combination therapy for ankylosing spondylitis hip joint lesion in Chinese population.

    abstract::To investigate the efficacy of etanercept and MTX (methotrexate) combination therapy in Chinese patients with ankylosing spondylitis hip joint lesion, the possible courses and maintenance protocol, altogether 97 ankylosing spondylitis patients fulfilling the modified New York criteria with hip joint lesion were enroll...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Lian F,Yang X,Liang L,Xu H,Zhan Z,Qiu Q,Ye Y

    更新日期:2012-06-01 00:00:00

  • Belimumab use, clinical outcomes and glucocorticoid reduction in patients with systemic lupus erythematosus receiving belimumab in clinical practice settings: results from the OBSErve Canada Study.

    abstract::To describe the characteristics of patients receiving belimumab, overall patterns of systemic lupus erythematosus (SLE) care, clinical outcomes, and changes in glucocorticoid dose following 6 months of therapy with belimumab, and healthcare resource utilization in belimumab users in Canadian clinical practice settings...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究


    authors: Touma Z,Sayani A,Pineau CA,Fortin I,Matsos M,Ecker GA,Chow A,Iczkovitz S

    更新日期:2017-06-01 00:00:00

  • Increased plasma levels of IL-21 and IL-23 in spondyloarthritis are not associated with clinical and MRI findings.

    abstract::We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Andersen T,Rasmussen TK,Hvid M,Holm CK,Madsen KJ,Jurik AG,Hokland M,Stengaard-Pedersen K,Schiøttz-Christensen B,Deleuran B

    更新日期:2012-02-01 00:00:00

  • The relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go test in patients with symptomatic knee osteoarthritis.

    abstract::Both self-reported and physical performance tests are used as outcome measures in knee osteoarthritis (OA). The aim of this study is to investigate the relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go (TUG) test in the patients with symptomatic knee OA. Eighty-nine patients ...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Sabirli F,Paker N,Bugdayci D

    更新日期:2013-10-01 00:00:00

  • Demographic and clinical characteristics of patients with ANCA-positive vasculitis in a Colombian University Hospital over a 12-year period: 2005-2017.

    abstract::Vasculitides associated with anti-neutrophil cytoplasmic antibodies are heterogeneous, systemic, low prevalence and high morbidity and mortality entities. They include granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis. In Latin America, there are few descripti...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Fernández-Ávila DG,Rondón-Carvajal J,Villota-Eraso C,Gutiérrez-Dávila JM,Contreras-Villamizar KM

    更新日期:2020-08-01 00:00:00

  • Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.

    abstract::A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspir...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Nakamura H,Okada A,Kawakami A,Yamasaki S,Ida H,Motomura M,Imanishi D,Eguchi K

    更新日期:2010-11-01 00:00:00

  • Functional genetic polymorphisms in interleukin-12B gene in association with systemic lupus erythematosus.

    abstract::Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Miteva LD,Manolova IM,Ivanova MG,Rashkov RK,Stoilov RM,Gulubova MV,Stanilova SA

    更新日期:2012-01-01 00:00:00

  • Capturing the enthesitis related arthritis contemporary profile of Caucasian patients in the era of biologics.

    abstract::To describe the profile of Enthesitis Related Arthritis' (ERA) patients, in the era of biologic DMARDs (bDMARDs). This retrospective cohort study included patients with ERA monitored on a 3-month schedule for at least 1 year. Their metric assessment included the disease status and damage by applying the contemporary t...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Deligeorgakis D,Trachana M,Pratsidou-Gertsi P,Dimopoulou D,Haidich AB,Garyfallos A

    更新日期:2020-06-01 00:00:00

  • A bibliometric analysis of the global research in ankylosing spondyloarthritis (2008-2017).

    abstract::The current study was to investigate the quantity and quality of researches in the field of ankylosing spondylitis, and to reveal the characteristics of worldwide productivity on this disease. This was a bibliometric study on ankylosing spondylitis using Web of Science. The numbers of papers, citations, research outpu...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Zhao X,Chen J,Pan Y,Feng H,Meng B,Meng Y

    更新日期:2019-06-01 00:00:00

  • Serum levels of interleukin 1-beta, tumor necrosis factor-alpha, soluble interleukin 2 receptor and soluble CD8 in seronegative spondylarthropathies.

    abstract::Seronegative spondylarthropathies are disorders with the same predisposing antigen, namely HLA B27, a class I molecule of the HLA system. The mechanisms of the different diseases are unknown, and there is no proof of immune system participation. We have investigated patients with spondylarthropathies in order to searc...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Toussirot E,Lafforgue P,Boucraut J,Despieds P,Schiano A,Bernard D,Acquaviva PC

    更新日期:1994-01-01 00:00:00

  • Echocardiographic findings and 24-h electrocardiographic Holter monitoring in patients with nodular and non-nodular rheumatoid arthritis.

    abstract::Echocardiographic examination and 24-h electrocardiographic Holter monitoring were carried out on 35 patients with nodular rheumatoid arthritis (RA) and 35 with non-nodular RA, who were matched with the nodular RA group regarding age, sex and BSA. A further 35 patients with osteoarthrosis and spondyloarthrosis matched...

    journal_title:Rheumatology international

    pub_type: 临床试验,杂志文章


    authors: Wisłowska M,Sypuła S,Kowalik I

    更新日期:1999-01-01 00:00:00

  • Celiac disease of the joint.

    abstract::A 42-year-old woman presented with a 3-week history of left knee pain and swelling. She had suffered dermatitis herpetiformis for 12 years, proved by skin biopsy. She had never been on gluten-free diet. Knee pain increased with motion and her gait was antalgic. On admission, she was mainly dependent on wheelchair due ...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Ozyemisci-Taskiran O,Cengiz M,Atalay F

    更新日期:2011-05-01 00:00:00

  • Toxic epidermal necrolysis in a child with lupus-associated pancreatitis.

    abstract::Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening dermatological conditions that are characterized by mucosal erosions, epidermal detachments and erosions. The most common causes of SJS and TEN are drugs; other causes such as systemic lupus erythematosus (SLE), vaccinations and i...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Marija S,Ivana B,Nina R,Dragan N,Zlatko B,Branislav J,Jelena P,Dusica S

    更新日期:2017-07-01 00:00:00

  • The effect of various disease-modifying anti-rheumatic drugs on the suppressive function of CD4⁺CD25⁺ regulatory T cells.

    abstract::Accumulating evidence suggests that defects in the function of CD4(+)CD25(+) regulatory T cells (Tregs) are important in immune-mediated diseases such as rheumatoid arthritis. Here, we investigated the effects of various disease-modifying anti-rheumatic drugs (DMARDs) on Treg function. Tregs and CD4(+)CD25(-) effector...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Oh JS,Kim YG,Lee SG,So MW,Choi SW,Lee CK,Yoo B

    更新日期:2013-02-01 00:00:00

  • Establishing hospital admission criteria of pediatric Henoch-Schonlein purpura.

    abstract::The current study aimed to define evidence-based admission criteria of pediatric Henoch-Schonlein purpura (HSP). In addition, we aimed to better characterize epidemiological and clinical features of pediatric HSP in Israel. We performed a retrospective cohort study of all children with HSP admitted during a 15 years p...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Masarweh K,Horovitz Y,Avital A,Spiegel R

    更新日期:2014-11-01 00:00:00

  • C-reactive protein-mediated complement activation in polymyalgia rheumatica and other systemic inflammatory diseases.

    abstract::An immunoglobulin-independent deposition of the complement (C) components C4 and C3 occurs on rat kidney medullary structures, when sera of patients with various inflammatory diseases are studied by indirect immunofluorescence. The diagnostic value of this new test (C4-C3-IFT) for polymyalgia rheumatica (PMR) is stres...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Vaith P,Hänsch GM,Peter HH

    更新日期:1988-01-01 00:00:00