Abstract:
:The presence of specific anti-Proteus antibodies in active, rheumatoid arthritis (RA) patients, has been demonstrated by four different techniques: indirect bacterial agglutination, ELISA, Western blotting and immunofluorescence. Furthermore, anti-HLA-DR4 tissue typing sera have been shown to bind to Proteus microorganisms, thereby suggesting some molecular similarity or cross-reactivity between bacteria and HLA antigens. The concept is proposed that Proteus-reactive arthritis occurs during active phases of RA and tissue damage is mediated through immunological activity involving HLA antigens.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Ebringer A,Khalafpour S,Wilson Cdoi
10.1007/BF00271885subject
Has Abstractpub_date
1989-01-01 00:00:00pages
223-8issue
3-5eissn
0172-8172issn
1437-160Xjournal_volume
9pub_type
杂志文章,评审abstract::3-Aminobenzamide is an inhibitor of poly-(ADP-ribosyl)ation. In concentrations from 3 to 10 mM it reduced the collagenase activity in culture supernatants of interleukin-1 beta-stimulated rabbit synovial fibroblasts. 3-Aminobenzoate, not an inhibiter of poly(ADP-ribosyl)ation, had no effect on collagenase activity at ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00301776
更新日期:1995-01-01 00:00:00
abstract::This study examines whether or not MBD4 polymorphism is a marker for rheumatoid arthritis (RA) susceptibility or severity for Chinese patients in Taiwan. This study included 193 patients with RA, while 190 unrelated healthy individuals living in Central Taiwan served as controls. The relationship between MBD4 polymorp...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1545-8
更新日期:2012-01-01 00:00:00
abstract::The neutrophilic granule protein proteinase 3 (PR3) is the preferred target antigen of anti-neutrophil cytoplasmic antibodies (ANCA) found in the serum of patients with Wegener's granulomatosis, a systemic small-vessel vasculitis. Due to the lack of data concerning the murine homologue of human PR3, we assessed the ne...
journal_title:Rheumatology international
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doi:10.1007/s00296-010-1672-2
更新日期:2011-08-01 00:00:00
abstract::Behçet's disease (BD) is a multi-system inflammatory disorder, in which cytokine balance is polarized to Th1. In this study, the cell surface molecule expression, Th1/Th2, inflammatory cytokine levels in blood, and synovial fluid of CD3(+) T lymphocytes in BD were investigated. The study group consisted of 10 BD, 10 a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2446-9
更新日期:2013-03-01 00:00:00
abstract::PADI4 that catalyzes the conversion of peptidylarginine to citrulline is associated with rheumatoid arthritis in some populations. The current study investigated the expressions of PADI4 in synovial fluid of RA (n = 73), osteoarthritis (OA, n = 96) and ankylosing spondylitis (AS, n = 32) using ELISA and western blotti...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0870-2
更新日期:2009-10-01 00:00:00
abstract::A meta-analysis was done with the final data from three trials that provided the first results relating to efficacy and safety of the new sustained-release (SR) formulation of etodolac versus established nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis (OA) of the knee. The studies were...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析
doi:10.1007/BF00290280
更新日期:1993-01-01 00:00:00
abstract::Rickettsia rickettsii, a tick borne disease, is the pathogen responsible for inducing Rocky Mountain Spotted Fever (RMSF), an illness that can progress to fulminant multiorgan failure and death. We present a case where R. rickettsii, acquired on a camping trip, precipitated a flare of peripheral arthritis and episcler...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04330-8
更新日期:2019-09-01 00:00:00
abstract::Therapeutics targeting sphingosine-1-phosphate (S1P), a kind of lipid mediator regulating immune cell trafficking, has been emerging rapidly as a novel line of regimen for autoimmune diseases, including rheumatoid arthritis (RA). Here, we propose that S1P-targeted therapy is beneficial not only for limiting inflammati...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1634-8
更新日期:2011-07-01 00:00:00
abstract::Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis affecting small vessels without necrotizing granulomatous inflammation and is commonly associated with necrotizing glomerulonephritis. Diagnosis is based on typical clinical features, the presence of antimyeloperoxidase-antineutrophil cytoplasmic anti...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0127-2
更新日期:2006-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1379-4
更新日期:2011-07-01 00:00:00
abstract::Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were studied prospectively for up to 12 months after beginning chrysotherapy. About half of the patients (group 1) exhibited pretreatment levels of monocyte IL-1 se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274840
更新日期:1990-01-01 00:00:00
abstract::Systemic immune defects might reflect severely dysregulated control of chronic inflammation related to disease progression. Th17/Treg cell imbalance has been demonstrated to be involved in rheumatoid arthritis (RA) pathogenesis. Despite controversial results, a growing anti-inflammatory role in this process has been r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2895-9
更新日期:2014-02-01 00:00:00
abstract::We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0988-2
更新日期:2010-04-01 00:00:00
abstract::Polyarteritis nodosa (PAN) related to hepatitis B is an uncommon vasculitis that is sometimes associated with the rapid progression of distal ischemia. A few recent reports have proposed the use of antiviral therapy. However, there is not yet a consensus for the standard treatment of this disease entity and none of th...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0103-x
更新日期:2006-08-01 00:00:00
abstract::Clinically diagnosed cases with different grades of rheumatoid arthritis (RA) were studied for (a) cryoglobulin content (b) constituents of cryoglobulins, and (c) rheumatoid factor (RF) titers in sera and cryoglobulins. Of 60 patients, 28 (46.66%) had significantly high levels of cryoglobulins and were mainly distribu...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541520
更新日期:1985-01-01 00:00:00
abstract::Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1547-6
更新日期:2012-01-01 00:00:00
abstract::The aims of this study were to assess the health-related quality of life (HRQoL) in patients with self-reported rheumatic diseases (RD), to classify self-reported rheumatic patients in groups according to their health state and to explore the associations between health status and sociodemographic variables. Data came...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3517-0
更新日期:2016-09-01 00:00:00
abstract::We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2137-y
更新日期:2012-10-01 00:00:00
abstract::The objective of the study is to assess the disease course and associated healthcare costs in a cohort of established rheumatoid arthritis (RA) patients in Turkey. The study cohort consisted of 75 RA patients from our outpatient clinic who took part in a previous multicenter study assessing RA-related healthcare costs...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04574-9
更新日期:2020-07-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04483-6
更新日期:2020-03-01 00:00:00
abstract::The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2639-2
更新日期:2013-07-01 00:00:00
abstract::Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastr...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-014-3109-9
更新日期:2015-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0723-4
更新日期:2009-03-01 00:00:00
abstract::The purpose of this study was to detect the frequency of inflammatory cervical spine changes and characteristic features such as resorption in rheumatoid arthritis (RA) with arthritis mutilans (AM) hand deformity. The series included 23 patients with AM hand deformity who fulfilled the 1987 American Rheumatism Associa...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960100114
更新日期:2001-08-01 00:00:00
abstract::Diagnostic accuracy of anti-DNase I antibodies measurement in a differentiation between SLE and other autoimmune rheumatic diseases was evaluated. The share of anti-DNase I and actin in the DNase I activity decrease in SLE was established. Serum samples were obtained from 54 patients with verified SLE, 52 control pati...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3437-z
更新日期:2016-04-01 00:00:00
abstract::The objective of this study is to describe the interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients of China, and to study clinical significance of high-resolution computed tomography (HRCT) in evaluation and treatment. One hundred and ten Chinese patients (79 women and 31 man) diagnosed with RA betwe...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1665-1
更新日期:2012-03-01 00:00:00
abstract::The aim of this study was to analyze the characteristics of patients with diffuse connective tissue diseases (CTDs) complicated by pneumomediastinum and identify the risk factors associated with increased mortality in these patients. Twenty-eight patients with CTD-associated pneumomediastinum, who were admitted to our...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3046-7
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of and evaluate the factors associated with fatigue patients with psoriatic arthritis (PsA) in an Asian population. METHODS:We used baseline data from a registry of patients with PsA attending an outpatient clinic of a tertiary hospital in Singapore. Demographic data and disease ch...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04678-2
更新日期:2020-11-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1176-0
更新日期:2010-09-01 00:00:00
abstract::The aim of our study was to compare the significance of risk factors for osteoporosis according to gender and menopausal state in patients with rheumatoid arthritis (RA). Bone mineral density (dual X-ray absorptiometry), cumulative glucocorticoid dose, age, disease duration, body mass index (BMI) and parameters of dis...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0576-x
更新日期:2008-09-01 00:00:00