Successful use of tofacitinib in the treatment of diffuse systemic sclerosis and axial spondyloarthritis: a case-based review.

abstract：:A 45-year-old female presented to the rheumatology clinic with complaint of pain and swelling of multiple small joints of the hands and feet. She also complained of cough and shortness of breath onset around the same time. Since her cyclic citrullinated peptide antibody (anti-CCP) and rheumatoid factor tests were posi...

journal_title：Rheumatology international

authors： Larson E,Etwaru D,Siva C,Lawlor K

更新日期：2011-12-01 00:00:00

abstract：:A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and h...

journal_title：Rheumatology international

authors： Abul-Kasim K,Nilsson T,Turesson C

更新日期：2012-06-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a rare systemic vasculitis affecting multiple organs. Current standard treatment includes the use of glucocorticoids and cyclophosphamide. Unfortunately, some patients do not respond to this treatment and other therapeutic options are needed. We present a case of a young male with refract...

journal_title：Rheumatology international

authors： Krusche M,Ruffer N,Kötter I

更新日期：2019-02-01 00:00:00

abstract：:Primary osteoarthritis (OA) is a multifactorial disease with several genetics factors involved. The COL2A1 gene is of particular interest because it encodes for the most abundant protein in articular cartilage. The aim was to evaluate the association of COL2A1 gene polymorphism with OA of the knee in Mexican Mestizo p...

journal_title：Rheumatology international

authors： Gálvez-Rosas A,González-Huerta C,Borgonio-Cuadra VM,Duarte-Salazár C,Lara-Alvarado L,de los Angeles Soria-Bastida M,Cortés-González S,Ramón-Gallegos E,Miranda-Duarte A

更新日期：2010-06-01 00:00:00

abstract：:Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) c...

journal_title：Rheumatology international

authors： Metsios GS,Moe RH,van der Esch M,van Zanten JJCSV,Fenton SAM,Koutedakis Y,Vitalis P,Kennedy N,Brodin N,Bostrom C,Swinnen TW,Tzika K,Niedermann K,Nikiphorou E,Fragoulis GE,Vlieland TPVM,Van den Ende CHM,Kitas GD,IMPACT

更新日期：2020-03-01 00:00:00

abstract：:Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. W...

journal_title：Rheumatology international

authors： Dass R,Barman H,Duwarah SG,Choudhury V,Jain P,Deka NM,Murari M

更新日期：2010-06-01 00:00:00

abstract：:An abnormal immune response towards the Epstein-Barr virus (EBV) has been documented in patients with rheumatoid arthritis (RA). To investigate whether these findings are due to the transformation event caused by EBV, RA blood mononuclear cells and monocyte-enriched preparations were incubated with two different EBV s...

journal_title：Rheumatology international

authors： Häupl T,Burmester GR,Hahn G,Feige U,Rordorf-Adam C,Kalden JR

更新日期：1989-01-01 00:00:00

abstract：:Although subclinical liver disease is common in systemic lupus erythematosus (SLE), strikingly high levels of liver enzymes are rare. Our aim was to determine the cause of high levels of liver enzymes in lupus patients, particularly in patients diagnosed with toxic hepatitis. We performed a retrospective chart review ...

journal_title：Rheumatology international

authors： Her M,Lee Y,Jung E,Kim T,Kim D

更新日期：2011-01-01 00:00:00

abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare but extremely disabling genetic disease of the skeletal system. This disease is characterized by progression of heterotopic ossification within skeletal muscles, ligaments and tendons. Most patients with FOP are misdiagnosed early in life before the appearance of h...

journal_title：Rheumatology international

authors： Ulusoy H

更新日期：2012-05-01 00:00:00

abstract：:Leflunomide is a new immunosuppressive medicine that has been effectively used in the therapy of rheumatoid arthritis and subsequently used with success in animal models and patients with systemic lupus erythematosus (SLE). However, its use has also been associated with significant and serious adverse reactions involv...

journal_title：Rheumatology international

authors： Wu GC,Xu XD,Huang Q,Wu H

更新日期：2013-02-01 00:00:00

abstract：:This retrospective medical chart review aimed to provide a current, real-world overview of biologic usage in patients with rheumatoid arthritis (RA) in Germany, Spain, and the UK, and estimate clinical and healthcare utilization outcomes associated with early versus late treatment. Adults (≥18 years) with a confirmed ...

journal_title：Rheumatology international

authors： Emery P,Solem C,Majer I,Cappelleri JC,Tarallo M

更新日期：2015-11-01 00:00:00

abstract：:The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...

journal_title：Rheumatology international

authors： Scott C,Okong'o L,Brice N,Murless S,Slamang W,Fadlelmola A,Consolaro A,Bovis F,Ruperto N,Paediatric Rheumatology International Trials Organisation (PRINTO).

更新日期：2018-04-01 00:00:00

abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

journal_title：Rheumatology international

authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

更新日期：2012-07-01 00:00:00

abstract：:Routine assessment of patient index data 3 (RAPID3) is a simple, valid and reliable tool designed to measure disease activity in patients with rheumatoid arthritis (RA). RA causes significant disability and diminishes health-related quality of life (HR-QoL). The aim of this study was to investigate how RAPID3 is relat...

journal_title：Rheumatology international

authors： Qorolli M,Rexhepi B,Rexhepi S,Mustapić M,Doko I,Grazio S

更新日期：2019-05-01 00:00:00

abstract：:The purpose of this study was to investigate specifically the correlation of hand functions determined by Duruoz hand index (DHI) with radiological findings and disease activity in rheumatoid arthritis (RA) patients. Forty-eight RA patients were evaluated with DHI questionnaire, disease activity score (DAS) 28 and mod...

journal_title：Rheumatology international

authors： Birtane M,Kabayel DD,Uzunca K,Unlu E,Tastekin N

更新日期：2008-03-01 00:00:00

abstract：:Intraperitoneal injection of pristane induced a clinical peripheral arthritis and/or tenosynovitis in 40% of 40 Balb/cJ/Ola mice. Hind paws were always affected first and fore paws were frequently involved. Involvement of knee joints was only apparent histologically. Some clinically unaffected animals and apparently u...

journal_title：Rheumatology international

authors： Hopkins SJ,Freemont AJ,Jayson MI

更新日期：1984-01-01 00:00:00

abstract：:The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...

journal_title：Rheumatology international

authors： Chen R,Wei Y,Cai Q,Duan S,Ren D,Shen J,He D,Fang M,Lv K,Cheng N,Sun S

更新日期：2011-12-01 00:00:00

abstract：:Kynurenic acid is an antagonist of ionotropic glutamate receptors. It has been found that glutamate antagonists inhibit proliferation of different human tumor cells. Since the hyperplasia of synovial fibroblasts is one of the most striking features of inflammatory arthritis, the main goals of this study were detection...

journal_title：Rheumatology international

authors： Parada-Turska J,Rzeski W,Zgrajka W,Majdan M,Kandefer-Szerszeń M,Turski W

更新日期：2006-03-01 00:00:00

abstract：:Using different monoclonal antibodies, we performed an immunofluorescent technique on labial salivary glands in order to investigate the immunological phenomena involved in Sjögren's syndrome (SS). An aberrant expression of HLA-DR molecules was detected on cytoplasm of epithelial labial salivary cells in 9 out of 19 (...

journal_title：Rheumatology international

authors： Caretto A,Ostuni PA,Chieco-Bianchi F,Pedini B,Spadaccino AC,Bagnasco M,Todesco S,Betterle C

更新日期：1995-01-01 00:00:00

abstract：:The aim of this study is to determine whether and to which extent pentosidine (PEN) is influenced in the case of advanced osteoarthritis (OA) in urine and in some tissues. Reverse phase HPLC method for PEN determination with fluorescence monitoring was utilized. Urinary pentosidine (U-PEN) and pyridinoline (U-PD) were...

journal_title：Rheumatology international

authors： Spacek P,Adam M

更新日期：2006-08-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) patients have high risk for anxiety and depression. We aimed to investigate the prevalence and risk factors of anxiety and depression in SLE patients in Southwest China. Participants were recruited by convenience sampling from Rheumatic Outpatient Clinic of West China Hospital Sichua...

journal_title：Rheumatology international

authors： Xie X,Wu D,Chen H

更新日期：2016-12-01 00:00:00

abstract：:To determine the possible diagnostic and prognostic value of cartilage biomarkers in early-stage progressive and nonprogressive knee osteoarthritis (OA) in a population-based cohort of middle-aged subjects with chronic knee pain. Design tibiofemoral (TF) and patellofemoral (PF) radiographs were graded in 128 subjects ...

journal_title：Rheumatology international

authors： Kumm J,Tamm A,Lintrop M,Tamm A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...

journal_title：Rheumatology international

authors： Hasegawa M,Sakai F,Konda N,Okabayashi A,Katsura H,Seto Y

更新日期：2018-06-01 00:00:00

abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...

journal_title：Rheumatology international

authors： Thapa R,Chakrabartty S

更新日期：2009-07-01 00:00:00

abstract：:Although arthroscopic surgery (AS) for knee osteoarthritis has been widely employed, scientific evidence is lacking. The purpose of this study was to investigate temporal changes in synovial fluid levels of biochemical markers associated with cartilage metabolism following AS. Twenty-five knees of 24 patients with med...

journal_title：Rheumatology international

authors： Nakajima A,Nakagawa K,Aoki Y,Sonobe M,Shibata Y,Yamazaki M,Murakami M

更新日期：2013-01-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is a rare disease, and large epidemiological studies of this disease are limited. Furthermore, it has been difficult to show the incidence and characteristics of severe AOSD complications due to the rarity of this disease. The aim of our study was to describe the demographics of AOSD...

journal_title：Rheumatology international

authors： Sakata N,Shimizu S,Hirano F,Fushimi K

更新日期：2016-10-01 00:00:00

abstract：:Reduction in jaw opening is a neglected symptom of giant cell arteritis (GCA) in clinical practice and in the scientific literature. We describe the case of a 71-year-old woman with GCA who was misdiagnosed as occipital neuritis and craniomandibular dysfunction because of headaches in the occipital region and reductio...

journal_title：Rheumatology international

authors： Kraemer M,Metz A,Herold M,Venker C,Berlit P

更新日期：2011-11-01 00:00:00

abstract：:The aim of the present study was to evaluate the effect of long-term leflunomide and methotrexate (MTX) therapy during the course of rheumatoid arthritis (RA) estimated by digital X-ray radiogrammetry (DXR) and computer-aided joint space analysis (CAJSA) as diagnostic tools for the quantification of disease-related pe...

journal_title：Rheumatology international

authors： Pfeil A,Lippold J,Eidner T,Lehmann G,Oelzner P,Renz DM,Hansch A,Wolf G,Hein G,Kaiser WA,Böttcher J

更新日期：2009-01-01 00:00:00

abstract：:Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...

journal_title：Rheumatology international

authors： Miteva LD,Manolova IM,Ivanova MG,Rashkov RK,Stoilov RM,Gulubova MV,Stanilova SA

更新日期：2012-01-01 00:00:00

abstract：:The current study was to investigate the quantity and quality of researches in the field of ankylosing spondylitis, and to reveal the characteristics of worldwide productivity on this disease. This was a bibliometric study on ankylosing spondylitis using Web of Science. The numbers of papers, citations, research outpu...

journal_title：Rheumatology international

authors： Zhao X,Chen J,Pan Y,Feng H,Meng B,Meng Y

更新日期：2019-06-01 00:00:00