Sacral inflammatory pseudotumor revealed by paraneoplastic syndrome.

Abstract:

:There is still debate on whether inflammatory pseudotumor should be considered benign or malignant. This lesion has only been reported twice in bone, apart from cases complicating foreign body reaction to joint replacement arthroplasty. We report here a third case, localized at the sacrum. A 31-year-old man had inflammatory dorsalgia and polyarthralgia without synovitis but with fever, asthenia, and erythema nodosa. Biological tests and X-rays were not informative, but technetium scintigraphy revealed a high level of left sacroiliac tracer binding. Several nonsteroidal anti-inflammatory drugs and sulfasalazine treatment were given over 3 months but ineffective. Pelvic magnetic resonance imaging showed an osteolytic tumor of the sacrum. Biopsy suggested a malignant fibrosarcoma, but complete evaluation after surgical resection demonstrated an inflammatory pseudotumor. All clinical symptoms disappeared within a few days after surgery, which is suggestive of a paraneoplastic syndrome. No relapse has occurred after 4 years.

journal_name

Rheumatol Int

authors

Allanore Y,Pham XV,Clerc DA,Menkès CJ,Kahan A

doi

10.1007/s00296-003-0365-5

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

166-8

issue

3

eissn

0172-8172

issn

1437-160X

journal_volume

24

pub_type

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