Abstract:
:Pancreatitis is uncommon in systemic lupus erythematosus (SLE) and is rarely reported in children, possibly being related to macrophage activation syndrome (MAS). The incidence of MAS in children with lupus pancreatitis is unknown, as is their prognosis. In this case-based review, we report a pediatric patient with SLE complicated with pancreatitis and MAS, and performed a literature review. We report an 11-year-old girl with SLE and MAS who developed pancreatitis on the second day of methylprednisolone pulse therapy (500 mg/day). We continued methylprednisolone pulse therapy, and performed three rounds of DNA-immunoadsorption and three rounds of hemoperfusion. A second course of methylprednisolone pulse therapy was initiated 9 days later. The patient received a monthly cyclophosphamide pulse therapy (10 mg/kg/day, 2 consecutive days every month) for 6 months, after which she was treated with mycophenolate mofetil 20 mg/kg/day. The condition of the patient gradually improved, her blood amylase and lipase decreased. She was in a stable condition during 13-month follow-up period. Review of the literature of pediatric patients with SLE and pancreatitis showed that there are 127 cases that have been reported in the past 30 years, 40 cases were excluded in our study because of inadequate information. Of the 87 patients included in our literature review, the mortality rate was 33.33%, and 52.86% of the patients with pancreatitis had MAS at the same time. Pancreatitis is uncommon in SLE, but must be suspected if a patient with SLE develops digestive symptoms. Patients with SLE with pancreatitis have a high incidence of MAS and high mortality rate; however, early recognition and effective treatment can relieve the disease symptoms.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Lin Q,Zhang M,Tang H,Shen Y,Zhu Y,Xu Q,Li Xdoi
10.1007/s00296-019-04388-4subject
Has Abstractpub_date
2020-05-01 00:00:00pages
811-819issue
5eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-019-04388-4journal_volume
40pub_type
杂志文章,评审abstract::A 7-year-old child was first admitted for persistent fever of 15-day duration and suspected meningitis. Kawasaki syndrome was lately diagnosed upon the recognition of an extensive diffuse coronary artery damage characterized by medium-sized aneurysms of the epicardial vessels. An eccentric thrombus along the inferior ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-011-1814-1
更新日期:2012-03-01 00:00:00
abstract::Increased QT interval dispersion has been associated with an increased risk for ventricular arrhythmias and sudden cardiac events. We examined the QT interval dispersion in 20 North Indian children with Kawasaki disease (KD) with no coronary artery abnormalities on echocardiography compared the same with matched contr...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1252-5
更新日期:2011-03-01 00:00:00
abstract::Heart rate variability (HRV) is a useful tool for the detection of sympathetic-parasympathetic balance in the autonomic nervous system. Autonomic nervous system involvement in patients with rheumatoid arthritis (RA) has rarely been studied and has shown conflicting results. Our purpose was to determine if HRV showed c...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0357-5
更新日期:2004-07-01 00:00:00
abstract::Behçet's disease (BD) is a variable vessel vasculitis characterized by recurrent oral and genital aphthosis accompanied by skin, ocular, gastrointestinal, neurologic, and articular involvement. BD is not common in childhood and the disease characteristics considerably differ between adults and children. 18 diagnostic/...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-018-4208-9
更新日期:2019-01-01 00:00:00
abstract::To develop a semi-automated method to quantify inflammation in sacroiliac (SI) joints by measuring bone marrow edema (BME) on MRI. The SCAISS was designed as an image-processing software. Validation followed: (1) three readers evaluated SI images of 23 patients with axial SpA and various levels of BME severity with th...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4104-3
更新日期:2018-10-01 00:00:00
abstract::The study includes a case report and a literature review. The main objective of this study is to present a case of spondylodiscitis due to a fungal pathogen, Blastoschizomyces capitatus and to review the published literature on this emergent fungus in etiology of spondylodiscitis, and osteomyelitis. Osteoarticular inv...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-009-0928-1
更新日期:2009-08-01 00:00:00
abstract::Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0502-9
更新日期:2005-05-01 00:00:00
abstract::Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS. W...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1033-1
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the adequacy of the following criteria for the classification of juvenile-onset spondyloarthropathies (JSpA): European Spondyloarthropathy Study Group criteria (ESSGCr) and Amor criteria (ACr) (proposed for adult SpA), Garmisch-Partenkirchen (G-PCr), seronegative enthe...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0460-2
更新日期:2005-08-01 00:00:00
abstract::The aim of this study was to analyze the characteristics of patients with diffuse connective tissue diseases (CTDs) complicated by pneumomediastinum and identify the risk factors associated with increased mortality in these patients. Twenty-eight patients with CTD-associated pneumomediastinum, who were admitted to our...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3046-7
更新日期:2014-12-01 00:00:00
abstract::There is still debate on whether inflammatory pseudotumor should be considered benign or malignant. This lesion has only been reported twice in bone, apart from cases complicating foreign body reaction to joint replacement arthroplasty. We report here a third case, localized at the sacrum. A 31-year-old man had inflam...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0365-5
更新日期:2004-05-01 00:00:00
abstract::Different genetic variants in estrogen receptor alpha (ESR1) have been shown to influence bone phenotypes including quantitative bone ultrasound in elderly. We aimed to investigate the role of ESR1 polymorphisms in bone mass assessed by calcaneal quantitative ultrasound (QUS) in a population of young adults. The study...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-017-3748-8
更新日期:2017-08-01 00:00:00
abstract::Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenic role. The presence of nailfold capillary abnormalities is useful in diagnosing SSc. Capillaroscopy, however, usually requires special equipment and may be time consuming. Dermatoscope has been presented as...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1532-0
更新日期:2011-12-01 00:00:00
abstract::Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we r...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-006-0152-1
更新日期:2006-10-01 00:00:00
abstract::This review explores the prevalence and factors associated with disturbed sleep for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis in order to clarify consistent findings in this otherwise disparate research field. The association of physical, demographic and psychological factors co...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-016-3589-x
更新日期:2017-02-01 00:00:00
abstract::We hypothesise that T-cell apoptosis and the percentage of T cells expressing molecules involved in apoptosis modulation (CD95, CD28) are altered at the inflammation site and in peripheral blood (PB) of children with juvenile idiopathic arthritis (JIA). Paired JIA samples of synovial fluid (SF) and PB ( n=7) and PB sa...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0263-2
更新日期:2003-05-01 00:00:00
abstract::The aim of the study was to analyze the concentrations of sTNFR1 and sTNFR2 in both plasma and synovial fluid of patients with primary knee osteoarthritis (OA) and to determine their relationship to self-reported pain, stiffness and physical function. Twenty-seven patients with knee OA and 19 healthy subjects were enr...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3016-0
更新日期:2014-12-01 00:00:00
abstract::Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence o...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2590-2
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-3992-6
更新日期:2018-06-01 00:00:00
abstract::The risk of herpes zoster among patients with juvenile idiopathic arthritis (JIA) exposed to biologics has not been evaluated. We determined incidence rates of herpes zoster among children with JIA in correlation with medication at time of occurrence and total drug exposure. The German biologics register database was ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3197-6
更新日期:2015-03-01 00:00:00
abstract::The objective of the study is to investigate the clinical characteristics and long-term prognosis including flares and organ damage in patients with giant cell arteritis (GCA) from a tertiary referral centre and compare these features in different subgroups. In this retrospective observational study, patients with GCA...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04730-1
更新日期:2021-02-01 00:00:00
abstract::In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541200
更新日期:1984-01-01 00:00:00
abstract::We have prepared antibody/3H-dsDNA immune complexes and have used three independent radioimmunoassays to quantitate their interaction with complement; the solution phase C1q assay, the Raji cell assay, and a complement-based red blood cell adherence assay (RBC-CF). Our results indicate that although there is reasonabl...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541220
更新日期:1981-01-01 00:00:00
abstract::To investigate the expression and effect of farnesoid X receptor (FXR) on systemic lupus erythematosus (SLE) liver dysfunction and indicate its hepatoprotective role and the immunomodulatory property. mRNA and protein levels of FXR were determined on the liver specimens of SLE patients with liver injury as well as MRL...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1874-2
更新日期:2012-06-01 00:00:00
abstract::Ankylosing spondylitis is a rather uncommon condition in the UAE. Over a period of 10 years. 28 hospital-based patients diagnosed as having AS were retrospectively studied. They included 17 Arabs and 11 Asians. The onset of AS in most patients in this study was in adulthood (mean age at onset was 27.7 years in Arabs a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960050033
更新日期:1998-01-01 00:00:00
abstract::The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-018-3964-x
更新日期:2018-04-01 00:00:00
abstract::In a study of 199 patients with rheumatoid arthritis, 68% were found to have tried 'alternative treatments'. Some treatments (acupuncture and faith healing) gave subjective benefit in nearly half those who tried them and were considered to be better than others (such as copper bracelets). No adverse reactions were rep...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541593
更新日期:1983-01-01 00:00:00
abstract::The aim of this study was to compare clinical symptoms, perceived health status, health resource use and psychosocial features in fibromyalgia (FM) patients at different health care levels. A total of 315 participants were recruited from primary care (PC) (n=101) and rheumatology settings (RS) (n=214). Subjects comple...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0818-y
更新日期:2009-08-01 00:00:00
abstract:UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-005-0603-0
更新日期:2005-09-01 00:00:00
abstract::Histoplasmosis is an important cause of morbidity in endemic areas of the USA. Infection is often asymptomatic but can cause a broad spectrum of pathology. Less commonly, histoplasmosis can present with a wide-range of rheumatologic manifestations. The aim of this review is to provide a synopsis of the rheumatologic m...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-013-2816-y
更新日期:2013-12-01 00:00:00