Abstract：
:We describe the case of a 59 year old man with systemic sclerosis and superficial siderosis of the central nervous system characterized by progressive worsening of walking with signs of pyramidal liberation associated with cerebellar ataxia and bilateral hypoacusia. Ferritin and oligoclonal bands were found on lumbar puncture and Magnetic Resonance Imaging of the brain and spinal cord revealed a rim of hypointensity in T2-weighted images enveloping the surface of brain and spinal cord, typical of hemosiderosis. Neurological complications, both central and peripheral, are thought to be rare and coincidental in systemic sclerosis; however over the past decade, some authors have reported a high incidence (up to 40%) of neurological involvement in the disease. In this report we consider the hypothesis that superficial siderosis may be a direct complication of systemic sclerosis. To our knowledge, this case represents the first description of superficial siderosis in a patient with systemic sclerosis.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Simeoni S,Puccetti A,Tinazzi E,Tomelleri G,Corrocher R,Lunardi Cdoi
10.1007/s00296-008-0523-xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
815-8issue
8eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
杂志文章abstract：:Polyarteritis nodosa (PAN) related to hepatitis B is an uncommon vasculitis that is sometimes associated with the rapid progression of distal ischemia. A few recent reports have proposed the use of antiviral therapy. However, there is not yet a consensus for the standard treatment of this disease entity and none of th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0103-x
更新日期：2006-08-01 00:00:00
abstract：:Diffuse idiopathic skeletal hyperostosis (DISH) is difficult to distinguish from various forms of inflammatory arthritis, including psoriatic arthritis (PsA), rheumatoid arthritis, and ankylosing spondylitis. A 67-year-old Japanese male had been treated for psoriasis vulgaris for 13 years. Numbness of his right arm an...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1368-7
更新日期：2012-05-01 00:00:00
abstract：:We determined whether repeated treatment with the tumor necrosis factor-α (TNF-α) antagonist etanercept can be effective after an initial clinical response to this drug is lost. We describe three female patients with active, refractory rheumatoid arthritis who were administered with a second course of etanercept after...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2124-3
更新日期：2012-11-01 00:00:00
abstract：:The family name of author Francesco La Torre was incorrect in the published article. The correct family name should read as La Torre F. ...
journal_title：Rheumatology international
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00296-018-4042-0
更新日期：2018-07-01 00:00:00
abstract：:Reported here is a 19-year-old female patient with familial Mediterranean fever who was seen for altered mental status and seizures. She was eventually diagnosed to have posterior reversible leukoencephalopathy syndrome. Although a variety of conditions have been reported in association with this syndrome, to our best...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1388-3
更新日期：2012-06-01 00:00:00
abstract：:Behçet's syndrome (BS) is a chronic (auto)-inflammatory disorder characterized by different clusters of symptoms, including mucocutaneous and ocular involvements. Interleukin-1 inhibitors anakinra (ANA), canakinumab (CAN), and gevokizumab (GEV) represent a promising therapeutic alternative in BS. To date, evidence on ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04259-y
更新日期：2019-06-01 00:00:00
abstract：:To investigate whether anti-inflammatory effects of HMG-CoA reductase inhibitor simvastatin (SMV) in rheumatoid arthritis (RA) is mediated by Toll-like receptor-2 (TLR-2) signal via inhibiting activation of RhoA, a small Rho GTPase that plays an important role in inflammatory responses. Peripheral blood monocytes from...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1510-6
更新日期：2011-11-01 00:00:00
abstract：:To translate and culturally adapt the Mayo Elbow Performance Score (MEPS), a widely used instrument for evaluating disability associated with elbow injuries, into Turkish (MEPS-T) and to determine psychometric properties of the translated version. The MEPS was translated into Turkish using published methodological gui...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3201-1
更新日期：2015-06-01 00:00:00
abstract：:We evaluated the presence of sarcopenia in a population of systemic sclerosis (SSc) patients, with respect to nutritional, clinical, and laboratory features. A total of 62 patients who met the ACR/EULAR 2013 classification criteria were enrolled. Sarcopenia was defined according to the Relative Skeletal Mass Index (RS...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04401-w
更新日期：2019-10-01 00:00:00
abstract：:Systemic sclerosis (SSc) is a generalized disorder characterized by fibrosis and vascular obliteration in the skin, lung, gastrointestinal tract, and kidney. One of its two subsets is a stable, limited cutaneous group (lSSc). Pulmonary involvement in scleroderma is common, and several types of pulmonary disorders are ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0230-y
更新日期：2002-09-01 00:00:00
abstract：:Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence o...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2590-2
更新日期：2013-06-01 00:00:00
abstract：:To describe the profile of Enthesitis Related Arthritis' (ERA) patients, in the era of biologic DMARDs (bDMARDs). This retrospective cohort study included patients with ERA monitored on a 3-month schedule for at least 1 year. Their metric assessment included the disease status and damage by applying the contemporary t...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04581-w
更新日期：2020-06-01 00:00:00
abstract：:An immunoglobulin-independent deposition of the complement (C) components C4 and C3 occurs on rat kidney medullary structures, when sera of patients with various inflammatory diseases are studied by indirect immunofluorescence. The diagnostic value of this new test (C4-C3-IFT) for polymyalgia rheumatica (PMR) is stres...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00271838
更新日期：1988-01-01 00:00:00
abstract：:Accumulating evidence suggests that defects in the function of CD4(+)CD25(+) regulatory T cells (Tregs) are important in immune-mediated diseases such as rheumatoid arthritis. Here, we investigated the effects of various disease-modifying anti-rheumatic drugs (DMARDs) on Treg function. Tregs and CD4(+)CD25(-) effector...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2365-9
更新日期：2013-02-01 00:00:00
abstract：:The clinical use of pulsed electromagnetic fields (PEMF) in osteoarticular pathology is widely extended, although the mechanisms involved are unknown. The aim of this study was to evaluate the action of a new protocol of treatment with PEMF on liquid medium cultures of fibroblast-like cells derivates of mononuclear pe...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1488-0
更新日期：2011-10-01 00:00:00
abstract：:Balneotherapeutic applications to treat rheumatic diseases have a long-term tradition and are based on established scientific principles, and the majority of rheumatic diseases most frequently include balneotherapy. However, as other therapeutic strategies, balneological interventions require scientific proof of their...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-005-0019-x
更新日期：2006-04-01 00:00:00
abstract：:Intraperitoneal injection of pristane induced a clinical peripheral arthritis and/or tenosynovitis in 40% of 40 Balb/cJ/Ola mice. Hind paws were always affected first and fore paws were frequently involved. Involvement of knee joints was only apparent histologically. Some clinically unaffected animals and apparently u...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541361
更新日期：1984-01-01 00:00:00
abstract：:The aim of this study was to investigate the percentage of regulatory T cells and the correlation with clinical activity in Behçet's disease. Forty Behçet's disease (BD) patients, 18 males and 22 females, were included in the study. The patients were diagnosed according to the published BD criteria. Twenty age- and se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2835-8
更新日期：2013-12-01 00:00:00
abstract：:Behçet's disease (BD) is a variable vessel vasculitis characterized by recurrent oral and genital aphthosis accompanied by skin, ocular, gastrointestinal, neurologic, and articular involvement. BD is not common in childhood and the disease characteristics considerably differ between adults and children. 18 diagnostic/...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-018-4208-9
更新日期：2019-01-01 00:00:00
abstract：:Several molecular epidemiological studies have been conducted in recent years to evaluate a possible association between the interferon regulatory factor 5 (IRF5) rs2004640 polymorphism and rheumatoid arthritis risk in diverse populations. However, the results remain conflicting rather than conclusive. Our aim was to ...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-013-2806-0
更新日期：2013-11-01 00:00:00
abstract：:Dermatomyositis (DM) is a rare inflammatory disorder affecting the muscle and skin. DM patients can present with spontaneous muscle hemorrhage, a potentially fatal complication. The best practice for management of hemorrhagic myositis in these patients remains unclear. Here we discuss the case of a patient who present...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-019-04501-7
更新日期：2020-02-01 00:00:00
abstract：:To validate the Thai language version of the Psoriasis Epidemiology Screening Tool (PEST) and the Early Arthritis for Psoriatic Patients Questionnaire (EARP), as well as also to develop a new tool for screening psoriatic arthritis (PsA) among psoriasis (Ps) patients. This was a cross-sectional study. Ps patients visit...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3513-4
更新日期：2016-10-01 00:00:00
abstract：:The aim of this study was to assess the changes in the characteristics of rheumatoid arthritis information on the Internet over a 15-year period and the positioning of Web sites posted by universities, hospitals, and medical associations. We replicated the methods of a 2001 study assessing rheumatoid arthritis informa...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3507-2
更新日期：2016-09-01 00:00:00
abstract：:We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two g...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04275-y
更新日期：2019-06-01 00:00:00
abstract：:Synovial fluids of patients suffering from rheumatoid arthritis contain elevated levels of granulocyte (PMN) elastase in complex with alpha 1-proteinase inhibitor (alpha 1-PI), whereas free-elastase activity is usually not detectable. This absence of free enzymatic activity in joint effusions has cast some doubt on th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00270466
更新日期：1987-01-01 00:00:00
abstract：:3-Aminobenzamide is an inhibitor of poly-(ADP-ribosyl)ation. In concentrations from 3 to 10 mM it reduced the collagenase activity in culture supernatants of interleukin-1 beta-stimulated rabbit synovial fibroblasts. 3-Aminobenzoate, not an inhibiter of poly(ADP-ribosyl)ation, had no effect on collagenase activity at ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00301776
更新日期：1995-01-01 00:00:00
abstract：:An imbalance in pro- and anti-inflammatory cytokines is suggested to contribute to tissue damage in rheumatoid arthritis (RA). This study was aimed at investigating profiles of cytokines in circulation and cytokines produced by mitogen-stimulated peripheral blood mononuclear cells (PBMC) in RA patients and healthy con...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3774-6
更新日期：2017-10-01 00:00:00
abstract：:We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0988-2
更新日期：2010-04-01 00:00:00
abstract：:To investigate the effects of TNF-alpha -308, -238 promoter polymorphisms on TNF-alpha transcription in B27 positive Chinese patients with ankylosing spondylitis (AS). The possible relationship between polymorphisms, MHC antigens, and quantitative TNF-alpha mRNA expression were evaluated. Single nucleotide polymorphis...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0671-z
更新日期：2008-12-01 00:00:00
abstract：:Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1877-z
更新日期：2012-08-01 00:00:00
