Abstract:
:We describe the case of a 59 year old man with systemic sclerosis and superficial siderosis of the central nervous system characterized by progressive worsening of walking with signs of pyramidal liberation associated with cerebellar ataxia and bilateral hypoacusia. Ferritin and oligoclonal bands were found on lumbar puncture and Magnetic Resonance Imaging of the brain and spinal cord revealed a rim of hypointensity in T2-weighted images enveloping the surface of brain and spinal cord, typical of hemosiderosis. Neurological complications, both central and peripheral, are thought to be rare and coincidental in systemic sclerosis; however over the past decade, some authors have reported a high incidence (up to 40%) of neurological involvement in the disease. In this report we consider the hypothesis that superficial siderosis may be a direct complication of systemic sclerosis. To our knowledge, this case represents the first description of superficial siderosis in a patient with systemic sclerosis.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Simeoni S,Puccetti A,Tinazzi E,Tomelleri G,Corrocher R,Lunardi Cdoi
10.1007/s00296-008-0523-xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
815-8issue
8eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
杂志文章abstract::Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA reve...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1007/s00296-011-2056-y
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274884
更新日期:1991-01-01 00:00:00
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更新日期:2009-08-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00