Abstract:
:We describe the case of a 59 year old man with systemic sclerosis and superficial siderosis of the central nervous system characterized by progressive worsening of walking with signs of pyramidal liberation associated with cerebellar ataxia and bilateral hypoacusia. Ferritin and oligoclonal bands were found on lumbar puncture and Magnetic Resonance Imaging of the brain and spinal cord revealed a rim of hypointensity in T2-weighted images enveloping the surface of brain and spinal cord, typical of hemosiderosis. Neurological complications, both central and peripheral, are thought to be rare and coincidental in systemic sclerosis; however over the past decade, some authors have reported a high incidence (up to 40%) of neurological involvement in the disease. In this report we consider the hypothesis that superficial siderosis may be a direct complication of systemic sclerosis. To our knowledge, this case represents the first description of superficial siderosis in a patient with systemic sclerosis.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Simeoni S,Puccetti A,Tinazzi E,Tomelleri G,Corrocher R,Lunardi Cdoi
10.1007/s00296-008-0523-xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
815-8issue
8eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
杂志文章abstract::Routine assessment of patient index data 3 (RAPID3) is a simple, valid and reliable tool designed to measure disease activity in patients with rheumatoid arthritis (RA). RA causes significant disability and diminishes health-related quality of life (HR-QoL). The aim of this study was to investigate how RAPID3 is relat...
journal_title:Rheumatology international
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
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journal_title:Rheumatology international
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,meta分析
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
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