Abstract：
:Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence of RA in 2007-2009 and the incidence of RA in 2008. On the basis of our previous validation study, the presence of RA was defined by the diagnostic code for RA with biologic or non-biologic disease-modifying anti-rheumatic drugs in the same claim in each year. To estimate the incidence of RA, we identified cases of RA in 2008 and set the 12-month period prior to 2008 as a disease-free period. Among the incident case of 2008, only patients who continued treatment in 2009 were defined as true incident case of RA in 2008. The corresponding prevalence estimates were 0.26 % (95 % CI 0.25-0.27) in 2006, 0.27 % (95 % CI 0.26-0.28) in 2007, and 0.27 % (95 % CI 0.26-0.28) in 2008. The incidence of RA in 2008 was estimated at 42/100,000 (95 % CI 29.3-54.7) in the general population of South Korea. Data gathered nationwide through the NHI yielded estimates of RA prevalence and incidence in South Korea. This study is the first report of nationwide prevalence and incidence of South Korea and those are comparable to values for other countries in Asia.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Sung YK,Cho SK,Choi CB,Bae SCdoi
10.1007/s00296-012-2590-2subject
Has Abstractpub_date
2013-06-01 00:00:00pages
1525-32issue
6eissn
0172-8172issn
1437-160Xjournal_volume
33pub_type
杂志文章abstract：:Interleukin-6 (IL-6) was detected at low levels in plasma [0.014 +/- 0.006 ng/ml (mean +/- SEM] and in high amounts in synovial fluid [SF; 2.6 +/- 2.2 ng/ml (mean +/- SEM)] of patients with rheumatoid arthritis. No correlation of IL-6 levels in plasma or SF with the ESR (n = 15) or with histological parameters of acut...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00307733
更新日期：1993-01-01 00:00:00
abstract：:Heart rate variability (HRV) is a useful tool for the detection of sympathetic-parasympathetic balance in the autonomic nervous system. Autonomic nervous system involvement in patients with rheumatoid arthritis (RA) has rarely been studied and has shown conflicting results. Our purpose was to determine if HRV showed c...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0357-5
更新日期：2004-07-01 00:00:00
abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0899-2
更新日期：2009-07-01 00:00:00
abstract：:Thrombotic microangiopathy (TMA)/thrombotic thrombocytopenic purpura (TTP) is a rare but potentially lethal condition requiring rapid recognition, diagnosis, and initiation of therapy. We experienced a case of a 61-year-old woman with primary Sjögren's syndrome (pSS) complicated with severe renal TMA/TTP following IgM...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1569-0
更新日期：2013-01-01 00:00:00
abstract：:Nailfold videocapillaroscopy was performed in 21 controls (C) and 21 patients (P) with systemic lupus erythematosus (SLE) classified according to the American College of Rheumatology, with, at least, 1 year of diagnosed disease and having low activity (MEX-SLEDAI) and sequel (SLICC) indexes at the time of the examinat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0033-z
更新日期：2006-05-01 00:00:00
abstract：:Several molecular epidemiological studies have been conducted in recent years to evaluate a possible association between the interferon regulatory factor 5 (IRF5) rs2004640 polymorphism and rheumatoid arthritis risk in diverse populations. However, the results remain conflicting rather than conclusive. Our aim was to ...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-013-2806-0
更新日期：2013-11-01 00:00:00
abstract：:The objective of the study is to assess the disease course and associated healthcare costs in a cohort of established rheumatoid arthritis (RA) patients in Turkey. The study cohort consisted of 75 RA patients from our outpatient clinic who took part in a previous multicenter study assessing RA-related healthcare costs...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04574-9
更新日期：2020-07-01 00:00:00
abstract：:The aim of this study was to investigate the influence of various weather parameters on pain intensity levels in patients with acute low back pain (LBP). We performed a secondary analysis using data from the PACE trial that evaluated paracetamol (acetaminophen) in the treatment of acute LBP. Data on 1604 patients with...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3419-6
更新日期：2016-05-01 00:00:00
abstract：:Among the clinical manifestations of systemic lupus erythematosus is an arthropathy, which is usually non-erosive. In many cases, the joint involvement is mild. A subset of patients has deforming, non-erosive Jaccoud's arthropathy, and a minority have an arthropathy with clinical findings similar to rheumatoid arthrit...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-008-0780-8
更新日期：2009-08-01 00:00:00
abstract：:Tumor necrosis factor (TNF) antagonists are among the most effective therapies for rheumatoid arthritis (RA), yet not all patients show a response. Using meta-analysis, this present study was designed to investigate whether or not the TNF-alpha promoter -308 A/G polymorphism is associated with responsiveness to anti-T...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-006-0175-7
更新日期：2006-12-01 00:00:00
abstract：:Sound epidemiological data are a basic requirement for decision making on the allocation of health care resources. Unfortunately, this is not the case in Estonia, where the paucity of epidemiological data has impeded health care planning for rheumatic conditions. The current paper presents the first effort to explore ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2473-6
更新日期：2013-04-01 00:00:00
abstract：:P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0307-8
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:The prevalence of dermatophytic infections in rheumatoid arthritis is unknown. This study investigated the prevalence of dermatophytosis in patients with rheumatoid arthritis and the relationship between sulfasalazine, low-dose methotrexate and steroid therapy. METHODS:We examined 53 consecutive patients wit...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0238-3
更新日期：2003-01-01 00:00:00
abstract：:To study the combined effect of both genetic and environmental factors in the age of rheumatoid arthritis onset. Patients (n = 507). Shared epitope characterization was performed using Lifecodes HLA-SSO. Genotyping of protein tyrosine phosphatase non-receptor 22 (PTPN22) rs2476601 and signal transducers and activators...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2090-9
更新日期：2012-10-01 00:00:00
abstract：:Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1547-6
更新日期：2012-01-01 00:00:00
abstract：:Psychiatric manifestations are common in systemic lupus erythematosus (SLE) and often represent a challenging diagnostic and therapeutic problem, mainly because the uncertainties of the pathogenic mechanisms. We report a case of acute psychosis occurring in a female with SLE due to the stress of having a severe diseas...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0479-2
更新日期：2008-02-01 00:00:00
abstract：:When compared to general population, patients with rheumatoid arthritis are at higher risk of some malignancies (especially lymphomas and lung cancer). Genetic predisposition, chronic inflammatory stimuli and viral infections are some of the reasons untreated patients are at higher risk. Clinical studies and national/...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04706-1
更新日期：2021-02-01 00:00:00
abstract：:Research suggests that health literacy (HL) is associated with rheumatoid arthritis (RA) patients' functional status. Single-item health literacy screening (SILS) questionnaires may establish patients' HL; however, the wording of SILS may be misinterpreted by RA patients as a query regarding physical limitations. Desp...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3238-9
更新日期：2015-09-01 00:00:00
abstract：:The capillaroscopic pattern in paraneoplastic Raynaud's phenomenon (RP) has not been investigated systematically and is not well-defined. Here, we present three case reports of patients with paraneoplastic rheumatic conditions, manifested with severe secondary RP with emphasis upon capillaroscopic findings. The first ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1715-8
更新日期：2013-06-01 00:00:00
abstract：:The purpose of this study was to investigate specifically the correlation of hand functions determined by Duruoz hand index (DHI) with radiological findings and disease activity in rheumatoid arthritis (RA) patients. Forty-eight RA patients were evaluated with DHI questionnaire, disease activity score (DAS) 28 and mod...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0461-z
更新日期：2008-03-01 00:00:00
abstract：:Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002960100105
更新日期：2001-05-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) patients have high risk for anxiety and depression. We aimed to investigate the prevalence and risk factors of anxiety and depression in SLE patients in Southwest China. Participants were recruited by convenience sampling from Rheumatic Outpatient Clinic of West China Hospital Sichua...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3559-3
更新日期：2016-12-01 00:00:00
abstract：:Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA reve...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04633-1
更新日期：2020-09-01 00:00:00
abstract：:Various surgical procedures including percutaneous and open release and arthroscopic procedures have been described to treat recalcitrant tennis elbow. We present the outcome of Boyd-McLeod surgical procedure for tennis elbow resistant to non-operative treatment in twenty-seven patients (twenty-nine limbs). Boyd McLeo...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1450-1
更新日期：2011-08-01 00:00:00
abstract：:Tuberculosis (TB) is an important preventable infection in patients with rheumatoid arthritis (RA). To determine the risk of TB in patients with RA by comparing with those with non-specific back pain (NSBP), and to identify the risk factors in the RA group. Medical data were retrieved from a centralized electronic dat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04583-8
更新日期：2020-06-01 00:00:00
abstract：:We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2137-y
更新日期：2012-10-01 00:00:00
abstract：:An imbalance in pro- and anti-inflammatory cytokines is suggested to contribute to tissue damage in rheumatoid arthritis (RA). This study was aimed at investigating profiles of cytokines in circulation and cytokines produced by mitogen-stimulated peripheral blood mononuclear cells (PBMC) in RA patients and healthy con...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3774-6
更新日期：2017-10-01 00:00:00
abstract：:To determine the "hand anatomic index" (HAI--a quantitative measure of hand deformity) in systemic sclerosis (scleroderma) and to compare it with the other measures of hand deformity and functional impairment. The HAI (measure of open hand span minus closed hand span/lateral height of hand) was determined in 30 patien...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0058-3
更新日期：2006-03-01 00:00:00
abstract：:To describe levels of daily physical activity and examine the extent of agreement between self-reported and objectively measured indices of physical activity, and characteristics associated with under or overestimated physical activity among persons with osteoarthritis (OA). Using cross-sectional data from the 2003-20...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3537-9
更新日期：2016-10-01 00:00:00
abstract：:Low molecular weight IgM (LMW IgM) is the monomeric subunit of the naturally occurring pentameric IgM. It is not seen in health but has been previously observed in systemic lupus erythematosus (SLE) particularly in those patients with active disease and may reflect an adverse prognostic finding. We have therefore stud...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF02274821
更新日期：1990-01-01 00:00:00
