Drug-induced lupus in anti-TNF-alpha therapy and its treatment with rituximab.

abstract：:One hundred and eighteen unrelated Greek patients with classic rheumatoid arthritis (RA) were tissue-typed for HLA-A, -B, -DR antigens and the frequency was compared to that of healthy controls. Greek RA patients regardless of sex, anatomical severity, seropositivity and age at disease onset are not associated with an...

journal_title：Rheumatology international

authors： Papasteriades CA,Kappou ID,Skopouli FN,Barla MN,Fostiropoulos GA,Moutsopoulos HM

更新日期：1985-01-01 00:00:00

abstract：:We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...

journal_title：Rheumatology international

authors： Andersen T,Rasmussen TK,Hvid M,Holm CK,Madsen KJ,Jurik AG,Hokland M,Stengaard-Pedersen K,Schiøttz-Christensen B,Deleuran B

更新日期：2012-02-01 00:00:00

abstract：:We aimed to determine left ventricular (LV) and right ventricular (RV) structure, function and mechanics, as well as heart rate variability (HRV), and their relationship, in patients with systemic sclerosis (SSc). The study included 41 SSc patients and 30 age-matched healthy volunteers. All the patients underwent clin...

journal_title：Rheumatology international

authors： Zlatanovic M,Tadic M,Celic V,Ivanovic B,Stevanovic A,Damjanov N

更新日期：2017-01-01 00:00:00

abstract：:Biological treatments aiming to neutralize TNF-alpha (tumour necrosis factor alpha) (infliximab, adalimumab and etanercept) are increasingly used to treat rheumatoid arthritis (RA). Although increased frequency has not been observed in randomized clinical trials with TNF-alpha antagonist agents, postmarketing surveill...

journal_title：Rheumatology international

authors： Inanc N,Direskeneli H

更新日期：2006-11-01 00:00:00

abstract：:Dermatomyositis (DM) is a rare inflammatory disorder affecting the muscle and skin. DM patients can present with spontaneous muscle hemorrhage, a potentially fatal complication. The best practice for management of hemorrhagic myositis in these patients remains unclear. Here we discuss the case of a patient who present...

journal_title：Rheumatology international

authors： Chandler JM,Kim YJ,Bauer JL,Wapnir IL

更新日期：2020-02-01 00:00:00

abstract：:Infliximab, a monoclonal chimeric anti-tumor necrosis factor alpha (anti-TNF-alpha) antibody, was tried in two patients suffering from severe refractory juvenile ankylosing spondylarthritis with disease duration of more than 10 years. To assess the response, validated clinical activity parameters were monitored prospe...

journal_title：Rheumatology international

authors： Schmeling H,Horneff G

更新日期：2004-05-01 00:00:00

abstract：:The aim of the study was to analyze the concentrations of sTNFR1 and sTNFR2 in both plasma and synovial fluid of patients with primary knee osteoarthritis (OA) and to determine their relationship to self-reported pain, stiffness and physical function. Twenty-seven patients with knee OA and 19 healthy subjects were enr...

journal_title：Rheumatology international

authors： Simão AP,Almeida TM,Mendonça VA,Santos SA,Gomes WF,Coimbra CC,Lacerda AC

更新日期：2014-12-01 00:00:00

abstract：:We evaluated the presence of sarcopenia in a population of systemic sclerosis (SSc) patients, with respect to nutritional, clinical, and laboratory features. A total of 62 patients who met the ACR/EULAR 2013 classification criteria were enrolled. Sarcopenia was defined according to the Relative Skeletal Mass Index (RS...

journal_title：Rheumatology international

authors： Corallo C,Fioravanti A,Tenti S,Pecetti G,Nuti R,Giordano N

更新日期：2019-10-01 00:00:00

abstract：:The cost-effectiveness of treatments that have the potential to change the "natural history" of a chronic progressive disease has to be evaluated over the long term. Cost-effectiveness estimates have been based on the concept that, with treatment, patients will not progress to the next level(s) of disease severity or ...

journal_title：Rheumatology international

authors： Benucci M,Saviola G,Baiardi P,Manfredi M

更新日期：2011-11-01 00:00:00

abstract：:Neurocognitive dysfunction and brain injury on magnetic resonance imaging (MRI) are common in patients with systemic lupus erythematosus (SLE) and are associated with increased morbidity and mortality. However, brain MRI is expensive, is restricted by payers, and requires high expertise. Neurocognitive assessment is a...

journal_title：Rheumatology international

authors： Roldan PC,Jung RE,Sibbitt WL,Qualls CR,Flores RA,Roldan CA

更新日期：2018-08-01 00:00:00

abstract：:The capillaroscopic pattern in paraneoplastic Raynaud's phenomenon (RP) has not been investigated systematically and is not well-defined. Here, we present three case reports of patients with paraneoplastic rheumatic conditions, manifested with severe secondary RP with emphasis upon capillaroscopic findings. The first ...

journal_title：Rheumatology international

authors： Lambova S,Müller-Ladner U

更新日期：2013-06-01 00:00:00

abstract：:Splenectomy may be necessary to treat systemic lupus erythematosus (SLE) patients with thrombocytopenia; however, whether performing a splenectomy on patients without SLE increases the subsequent risk of SLE remains unknown. Therefore, this study was conducted to determine the association between splenectomy and SLE. ...

journal_title：Rheumatology international

authors： Hsu CY,Chen HJ,Hsu CY,Kao CH

更新日期：2016-02-01 00:00:00

abstract：:Healthy human sexuality is integral to a well-lived life. Recent studies reported that sexual problems were common in patients with ankylosing spondylitis (AS) in relation to the consequences of the illness such as pain, stiffness of the spine and depression. Twenty-three female patients with AS and 27 healthy female ...

journal_title：Rheumatology international

authors： Demir SE,Rezvani A,Ok S

更新日期：2013-01-01 00:00:00

abstract：:The aim of our study was to compare the significance of risk factors for osteoporosis according to gender and menopausal state in patients with rheumatoid arthritis (RA). Bone mineral density (dual X-ray absorptiometry), cumulative glucocorticoid dose, age, disease duration, body mass index (BMI) and parameters of dis...

journal_title：Rheumatology international

authors： Oelzner P,Schwabe A,Lehmann G,Eidner T,Franke S,Wolf G,Hein G

更新日期：2008-09-01 00:00:00

abstract：:We hypothesise that T-cell apoptosis and the percentage of T cells expressing molecules involved in apoptosis modulation (CD95, CD28) are altered at the inflammation site and in peripheral blood (PB) of children with juvenile idiopathic arthritis (JIA). Paired JIA samples of synovial fluid (SF) and PB ( n=7) and PB sa...

journal_title：Rheumatology international

authors： Knipp S,Feyen O,Ndagijimana J,Niehues T

更新日期：2003-05-01 00:00:00

abstract：:Arthrocutaneous disorders including Reiter's syndrome, psoriasiform rashes, and other forms of chronic arthritis and enthesopathy, such as psoriatic arthritis, occur with an increased prevalence in the setting of HIV infection. Herein we describe the spectrum and prevalence of musculoskeletal and allied skin disorders...

journal_title：Rheumatology international

authors： Brancato L,Itescu S,Skovron ML,Solomon G,Winchester R

更新日期：1989-01-01 00:00:00

abstract：:Patients with rheumatoid arthritis (RA) have an increased cardiovascular (CV) risk. This study aimed to analyze the effects of Tofacitinib treatment, a Janus kinase inhibitor, on atherosclerosis in patients with RA. Patients with an active RA (28-joint disease activity score-erythrocyte sedimentation rate > 3.2) despi...

journal_title：Rheumatology international

authors： Kume K,Amano K,Yamada S,Kanazawa T,Ohta H,Hatta K,Amano K,Kuwaba N

更新日期：2017-12-01 00:00:00

abstract：:Tumor necrosis factor (TNF) antagonists are among the most effective therapies for rheumatoid arthritis (RA), yet not all patients show a response. Using meta-analysis, this present study was designed to investigate whether or not the TNF-alpha promoter -308 A/G polymorphism is associated with responsiveness to anti-T...

journal_title：Rheumatology international

authors： Lee YH,Rho YH,Choi SJ,Ji JD,Song GG

更新日期：2006-12-01 00:00:00

abstract：:The aim of this study was to evaluate whether cyclosporin A (CsA) influences the radiological disease progression in early rheumatoid arthritis (RA) patients in comparison with other disease-modifying drugs (DMARDs). A total of 103 early RA patients, without prior use of DMARDs, were randomized to receive CsA (3 mg/kg...

journal_title：Rheumatology international

authors： Drosos AA,Voulgari PV,Katsaraki A,Zikou AK

更新日期：2000-01-01 00:00:00

abstract：:Familial Mediterranean fever is characterized by self-limited attacks of serositis and arthritis. However, substantial number of patients suffer from chronic complications of this disease, primarily involving musculoskeletal system. Treatment for these complications is challenging due to limited evidence. Interleukin-...

journal_title：Rheumatology international

authors： Karadeniz H,Güler AA,Atas N,Satış H,Salman RB,Babaoglu H,Tufan A

更新日期：2020-01-01 00:00:00

abstract：:Methotrexate (MTX) is commonly employed as the initial DMARD used for the treatment of rheumatoid arthritis (RA). We aimed to contribute to the safety profile of MTX by assessing its cumulative effect on renal filtration. A total of 52 RA adult female patients with normal baseline serum creatinine and GFR at the initi...

journal_title：Rheumatology international

authors： Amin A,Effat D,Goher N,Ramadan B

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:To identify recommendations on the diagnosis and management of rheumatoid arthritis (RA) supported by low recommendation grades, to study the causes of this low grading, and to propose solutions. METHODS:A group of six rheumatologists, with extensive experience in the development of systematic reviews, revi...

journal_title：Rheumatology international

authors： Ortiz AM,Silva Fernández L,Villaverde V,Abad MÁ,Maneiro JR,Candelas G,Gómez S,Valderrama M,Montoro M

更新日期：2021-01-01 00:00:00

abstract：:We investigated the overall frequency of anti-phospholipid syndrome (APS) occurrence in Korean patients with consecutively detected anti-phospholipid antibodies with an interval of 12 weeks (persistent aPLs). We retrospectively reviewed the results of blood tests of aPLs in 14,889 patients in whom aPL tests were perfo...

journal_title：Rheumatology international

authors： Choi H,Ahn SS,Song JJ,Park YB,Song J,Lee SW

更新日期：2019-08-01 00:00:00

abstract：:The results of some epidemiological studies point to the presence of an increased risk of cardiovascular disease (CVD), particularly atherosclerosis and congestive heart failure (CHF) in rheumatoid arthritis (RA). At least 50% of abnormalities remained asymptomatic. Pathological conditions contributing to myocardial d...

journal_title：Rheumatology international

authors： Wislowska M,Jaszczyk B,Kochmański M,Sypuła S,Sztechman M

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...

journal_title：Rheumatology international

authors： Swinkels RA,Bouter LM,Oostendorp RA,van den Ende CH

更新日期：2005-09-01 00:00:00

abstract：:Using different monoclonal antibodies, we performed an immunofluorescent technique on labial salivary glands in order to investigate the immunological phenomena involved in Sjögren's syndrome (SS). An aberrant expression of HLA-DR molecules was detected on cytoplasm of epithelial labial salivary cells in 9 out of 19 (...

journal_title：Rheumatology international

authors： Caretto A,Ostuni PA,Chieco-Bianchi F,Pedini B,Spadaccino AC,Bagnasco M,Todesco S,Betterle C

更新日期：1995-01-01 00:00:00

abstract：:Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastr...

journal_title：Rheumatology international

authors： Slim M,Calandre EP,Rico-Villademoros F

更新日期：2015-03-01 00:00:00

abstract：:Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...

journal_title：Rheumatology international

authors： Hussain KS,Gulati R,Satheesh S,Negi VS

更新日期：2021-02-01 00:00:00

abstract：:To investigate the clinical manifestations and outcomes of musculoskeletal (MSK) nontuberculous mycobacterium (NTM) infections. This study was a retrospective cohort study using the Siriraj Hospital database from 2005 to 2017. Enrolled were all patients aged 15 or older who had an MSK infection with NTM identified in ...

journal_title：Rheumatology international

authors： Napaumpaiporn C,Katchamart W

更新日期：2019-10-01 00:00:00

abstract：:Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE) are common systemic autoimmune diseases, which impact not only patient health but also their quality of life. miRNA-146a is a microRNA that participates in the pathophysiology of SjS and SLE. In this investigation, we conducted a meta-analysis to determin...

journal_title：Rheumatology international

authors： Sun HY,Lv AK,Yao H

更新日期：2017-08-01 00:00:00