Abstract:
:The aim of our study was to compare the significance of risk factors for osteoporosis according to gender and menopausal state in patients with rheumatoid arthritis (RA). Bone mineral density (dual X-ray absorptiometry), cumulative glucocorticoid dose, age, disease duration, body mass index (BMI) and parameters of disease activity and bone turnover were registered in 343 postmenopausal women, 100 premenopausal women and 108 men with RA. Osteoporosis was found in a significantly higher percentage in postmenopausal women (55.7%) and in men (50.5%) in comparison with premenopausal women (18%; P < 0.001). The following risk factors for osteoporosis were found: older age, low BMI and high cumulative glucocorticoid dose in postmenopausal women, low BMI and high cumulative glucocorticoid dose in men and low BMI in premenopausal women. There is a very high prevalence of osteoporosis not only in postmenopausal women but also in men with RA. Osteoporosis risk factors are strongly dependent from gender and menopausal state.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Oelzner P,Schwabe A,Lehmann G,Eidner T,Franke S,Wolf G,Hein Gdoi
10.1007/s00296-008-0576-xsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
1143-50issue
11eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
杂志文章abstract::The main goal of this project was to identify the presence of fibromyalgia (FM) subgroups using a simple and frequently used clinical tool, the Fibromyalgia Impact Questionnaire (FIQ). A total of 61 women diagnosed with FM participated in this study. FM subgroups were created by applying a hierarchical cluster analysi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0722-5
更新日期:2009-03-01 00:00:00
abstract::Paediatric leg pains, long described as 'growing pains', frequently present to clinicians, are prevalent in early childhood, disrupt sleep, and distress affected children and parents. There are many cited associations, but no defined leg pain sub-types, nor revealed predictive factors. We explored the implicated facto...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4056-7
更新日期:2018-07-01 00:00:00
abstract::Pancreatitis is uncommon in systemic lupus erythematosus (SLE) and is rarely reported in children, possibly being related to macrophage activation syndrome (MAS). The incidence of MAS in children with lupus pancreatitis is unknown, as is their prognosis. In this case-based review, we report a pediatric patient with SL...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04388-4
更新日期:2020-05-01 00:00:00
abstract::Intraocular inflammation is one of the more relevant complications of Behçet's disease (BD), which tends to respond poorly to different medications. The ocular histopathologic changes are basically identical to those occurring in other organs and consist in a necrotizing leukocytoclastic obliterative vasculitis, which...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-017-3775-5
更新日期:2018-01-01 00:00:00
abstract::Autoantibodies have been detected in systemic sclerosis patients, and typical clinical features regarding organ involvement by each autoantibody have been reported. To reveal differences in exercise intolerance in patients with either anti-topoisomerase-I or anti-centromere antibodies, 53 systemic sclerosis patients w...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2541-y
更新日期:2013-11-01 00:00:00
abstract::The prevalence of overweight and obesity in patients with fibromyalgia is high, which makes these patients more likely to trigger metabolic changes. It is also uncertain whether the clinical manifestations of fibromyalgia alter the metabolism in these patients. This study investigates the influence of adiposity indica...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-2988-0
更新日期:2014-11-01 00:00:00
abstract::Leflunomide is a new immunosuppressive medicine that has been effectively used in the therapy of rheumatoid arthritis and subsequently used with success in animal models and patients with systemic lupus erythematosus (SLE). However, its use has also been associated with significant and serious adverse reactions involv...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-012-2508-z
更新日期:2013-02-01 00:00:00
abstract::The aim of this study was to investigate the percentage of regulatory T cells and the correlation with clinical activity in Behçet's disease. Forty Behçet's disease (BD) patients, 18 males and 22 females, were included in the study. The patients were diagnosed according to the published BD criteria. Twenty age- and se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2835-8
更新日期:2013-12-01 00:00:00
abstract::Chondrocyte structure and function under the influence of two gold-containing therapeutic agents, aurothioglucose and triethylphosphine gold, were studied in a monolayer culture system for cultivating lapine articular chondrocytes. The functional parameters investigated were chondrocyte proliferation and the incorpora...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541144
更新日期:1983-01-01 00:00:00
abstract::Systemic lupus erythematosus is an autoimmune disease with protean manifestation. Arthritis is one of the most common manifestations seen in SLE. Anti-CCP Ab is a recently described autoantibody that has been claimed as a most sensitive and specific marker for the diagnosis of RA. Study was performed to see whether an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1374-9
更新日期:2011-06-01 00:00:00
abstract::The aim was to further characterize the SKG model of rheumatoid arthritis (RA) and its potential for studying intervention treatments, with special focus on bone targeting therapies. Three individual studies were conducted, using a total of 71 SKG mice, comparing arthritis induction with mannan versus zymosan A, femal...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2500-7
更新日期:2013-05-01 00:00:00
abstract::A 44-year-old man with intermittent asymmetric migratory oligoarthritis lasting the recent decade was admitted to our hospital. Considerable specific biomarkers for rheumatoid arthritis such as anti-agalactosyl IgG antibody are all negative. He was diagnosed as palindromic rheumatism (PR). Although hand X-rays showed ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0654-0
更新日期:2008-11-01 00:00:00
abstract::Reported here is a 19-year-old female patient with familial Mediterranean fever who was seen for altered mental status and seizures. She was eventually diagnosed to have posterior reversible leukoencephalopathy syndrome. Although a variety of conditions have been reported in association with this syndrome, to our best...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1388-3
更新日期:2012-06-01 00:00:00
abstract::The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-018-3977-5
更新日期:2018-04-01 00:00:00
abstract::The assessment of skin fibrosis is vital for the diagnosis and monitoring of treatment in the systemic sclerosis (SSc)-a severe autoimmune disease. The elastography is a technique of skin fibrosis assessment through the evaluation of skin strain. We compared the efficacy of the shear wave elastography (SWE) and common...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04539-y
更新日期:2020-05-01 00:00:00
abstract::We present a rare case of retinoid-induced sclerotic changes of lumbar spine and femur demonstrated by dual energy x-ray absorptiometrie (DEXA). The patient had flowing ossification along thoracic spine resembling diffuse idiopathic skeletal hyperostosis (DISH), but there was no ligament calcification in the lumbar sp...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0391-3
更新日期:2004-09-01 00:00:00
abstract::Kynurenic acid is an antagonist of ionotropic glutamate receptors. It has been found that glutamate antagonists inhibit proliferation of different human tumor cells. Since the hyperplasia of synovial fibroblasts is one of the most striking features of inflammatory arthritis, the main goals of this study were detection...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0057-4
更新日期:2006-03-01 00:00:00
abstract::We studied and characterized anti-bovine beta 2-glycoprotein I antibodies (aB beta 2-GPI) in sera from patients with antiphospholipid syndrome (APS) by ELISA. Bovine beta 2-glycoprotein I (beta 2-GPI) was purified by heparin affinity and DEAE ion-exchange chromatography, and identified on immunoblots using a monoclona...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00286762
更新日期:1995-01-01 00:00:00
abstract::A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and h...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1464-8
更新日期:2012-06-01 00:00:00
abstract::Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in RA patients is stab...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1765-y
更新日期:2012-05-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a severe complex rheumatic disease, but good estimate of its prevalence and risk factors is lacking in China. The aim of the study was to explore the prevalence of SLE and risk factors in rural areas of Anhui Province of China. Eleven counties were randomly selected in Anhui Provi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2902-1
更新日期:2014-03-01 00:00:00
abstract::It is proposed that synovial fluid biomarkers may help in differentiating the type of arthritis. The aim of study is to determine whether synovial fluid adenosine deaminase (ADA) and high-sensitivity C-reactive protein (hs-CRP) can be useful in this regard. A total of 75 patients with knee monoarthritis that were admi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1602-3
更新日期:2012-01-01 00:00:00
abstract::Systemic sclerosis is a connective tissue disease, which may lead to elevated pulmonary arterial pressure due to pulmonary arterial hypertension and/or left ventricular diastolic dysfunction. Uric acid (UA) has been shown to be elevated in patients with pulmonary hypertension (PH) and heart failure. We aimed to invest...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1557-4
更新日期:2011-02-01 00:00:00
abstract::Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease affecting predominantly sacroiliac joints and axial skeleton. axSpA progression being irregular and hardly predictable, identifying functional decline is particularly important in patient with axSpA to allow delivery of timely and targeted int...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04396-4
更新日期:2019-10-01 00:00:00
abstract::The aim of our study was to evaluate effectiveness of ultrasound treatment applied with exercise therapy in patients with ankylosing spondylitis. Fifty-two patients, who were diagnosed according to modified New York criteria, were aged 25-60, and have spine pain, were randomly assigned to two groups. Ultrasound (US) a...
journal_title:Rheumatology international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00296-016-3441-3
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of and evaluate the factors associated with fatigue patients with psoriatic arthritis (PsA) in an Asian population. METHODS:We used baseline data from a registry of patients with PsA attending an outpatient clinic of a tertiary hospital in Singapore. Demographic data and disease ch...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04678-2
更新日期:2020-11-01 00:00:00
abstract::To validate the Thai language version of the Psoriasis Epidemiology Screening Tool (PEST) and the Early Arthritis for Psoriatic Patients Questionnaire (EARP), as well as also to develop a new tool for screening psoriatic arthritis (PsA) among psoriasis (Ps) patients. This was a cross-sectional study. Ps patients visit...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3513-4
更新日期:2016-10-01 00:00:00
abstract::Our aim was to investigate the relationship between the DNA methylation status of glucocorticoid receptor (GR) gene promoter and mRNA expression level of GRα gene of peripheral blood mononuclear cells (PBMCs) in patients with systemic lupus erythematosus (SLE). Fifteen newly emerging SLE patients and fifteen healthy c...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-015-3266-5
更新日期:2015-08-01 00:00:00
abstract::The aim of this study is to observe the effect of different treatment time of millimeter wave (MMW) on chondrocyte apoptosis, caspase-3, caspase-8, and matrix metalloproteinase-13 (MMP-13) in rabbit knee osteoarthritis induced by anterior cruciate ligament transection (ACLT). Thirty-two New Zealand White rabbits were ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2080-y
更新日期:2012-09-01 00:00:00
abstract::In Spain, the QUANTUM project has been promoted to reduce variability in clinical practice and improve the care and quality of life of people with psoriatic arthritis (PsA) by accrediting PsA units throughout the Spanish national health system. To present the results of this approach which sought to ensure an optimum ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04632-2
更新日期:2020-11-01 00:00:00