Abstract：
:The assessment of skin fibrosis is vital for the diagnosis and monitoring of treatment in the systemic sclerosis (SSc)-a severe autoimmune disease. The elastography is a technique of skin fibrosis assessment through the evaluation of skin strain. We compared the efficacy of the shear wave elastography (SWE) and commonly used modified Rodnan skin score (RSS) in skin fibrosis assessment in SSc. The study included 40 SSc patients and 28 healthy individuals, with the exclusion of individuals with other skin/autoimmune diseases. Skin thickness using RSS and skin strain using SWE were assessed in the same 20 body localizations. Subjects' informed consent and the bioethics committee approval were obtained. Elastographic skin strain correlated positively with both partial and overall RSS values, with strong positive correlation (r ≥ 0.75) for hands and fingers localizations in particular. In SSc patients with normal RSS values, the elastographic strain was significantly higher than in healthy controls. Elastographic strain of fingers' skin evaluated in SWE is highly accurate for distinguishing SSc patients (sensitivity 0.897-0.923, specificity 0.929-0.964, positive predictive value 0.946-0.973, negative predictive value 0.867-0.900). ESW results are substantially more reproducible than those of RSS examination (intraclass correlation coefficients: 0.987 vs. 0.941). The shear wave elastography is more reproducible and has higher sensitivity than RSS in the evaluation of skin condition in SSc, especially in case of changes non-detectable on physical evaluation, indicating it might become a useful tool in SSc diagnosis.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Sobolewski P,Maślińska M,Zakrzewski J,Paluch Ł,Szymańska E,Walecka Idoi
10.1007/s00296-020-04539-ysubject
Has Abstractpub_date
2020-05-01 00:00:00pages
737-745issue
5eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-020-04539-yjournal_volume
40pub_type
杂志文章abstract：:Tumor necrosis factor (TNF) antagonists are among the most effective therapies for rheumatoid arthritis (RA), yet not all patients show a response. Using meta-analysis, this present study was designed to investigate whether or not the TNF-alpha promoter -308 A/G polymorphism is associated with responsiveness to anti-T...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-006-0175-7
更新日期：2006-12-01 00:00:00
abstract：:The results from previous studies on association of IL-6 -174 G/C and -572 G/C polymorphisms with the risk of systemic lupus erythematosus (SLE) remained inconsistent. Therefore, a meta-analysis was performed to assess the association between these two polymorphisms and SLE susceptibility. A literature-based search wa...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00296-013-2855-4
更新日期：2014-02-01 00:00:00
abstract：:The objectives of this study are to evaluate the prevalence of radiographic hand osteoarthritis (OA) in Chuvashian community-based sample and its associations with age, sex, body mass index (BMI), smoking, and alcohol consumption. The study population was comprised of Chuvashians (443 males, age 47.4 ± 17.0 years and ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0920-9
更新日期：2009-11-01 00:00:00
abstract：:Adult-onset Still's disease (AOSD) is a rare disease, and large epidemiological studies of this disease are limited. Furthermore, it has been difficult to show the incidence and characteristics of severe AOSD complications due to the rarity of this disease. The aim of our study was to describe the demographics of AOSD...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3546-8
更新日期：2016-10-01 00:00:00
abstract：:Antibodies to citrullinated proteins and rheumatoid factor (RF) are widely used in patients with rheumatoid arthritis (RA) and the antibodies to citrullinated proteins appear to be the most specific markers of the disease. The objective was to compare the diagnostic performance of the anti-cyclic citrullinated peptide...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0980-x
更新日期：2010-02-01 00:00:00
abstract：:Sarcoidosis is a chronic, multisystemic, non-caseating granulomatous disease of unknown etiology. Nasopharyngeal involvement is very rare in sarcoidosis. The objective of this report was to evaluate a rare involvement of sarcoidosis. This report includes a case of nasopharyngeal sarcoidosis. A 51-year-old female with ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1866-2
更新日期：2012-05-01 00:00:00
abstract：:Fluoride excess primarily effects dental and skeletal tissues. leading to a condition known as endemic fluorosis. The radiological and clinical features of endemic fluorosis vary in different parts of the world. The aim of this study was to investigate the clinical and radiological features of endemic fluorosis in Tur...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960100132
更新日期：2001-09-01 00:00:00
abstract：:Polyarteritis nodosa (PAN) related to hepatitis B is an uncommon vasculitis that is sometimes associated with the rapid progression of distal ischemia. A few recent reports have proposed the use of antiviral therapy. However, there is not yet a consensus for the standard treatment of this disease entity and none of th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0103-x
更新日期：2006-08-01 00:00:00
abstract：:The purpose of this study was to determine the association of fibromyalgia (FM) with temporomandibular disorder (TMD) and masticatory myofascial pain (MMP). Thirty-one consecutive women diagnosed as having FM according to American College of Rheumatology criteria and 21 consecutive women diagnosed as having TMD were i...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0251-z
更新日期：2007-04-01 00:00:00
abstract：:Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we r...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-006-0152-1
更新日期：2006-10-01 00:00:00
abstract：:To investigate whether anti-inflammatory effects of HMG-CoA reductase inhibitor simvastatin (SMV) in rheumatoid arthritis (RA) is mediated by Toll-like receptor-2 (TLR-2) signal via inhibiting activation of RhoA, a small Rho GTPase that plays an important role in inflammatory responses. Peripheral blood monocytes from...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1510-6
更新日期：2011-11-01 00:00:00
abstract：:When compared to general population, patients with rheumatoid arthritis are at higher risk of some malignancies (especially lymphomas and lung cancer). Genetic predisposition, chronic inflammatory stimuli and viral infections are some of the reasons untreated patients are at higher risk. Clinical studies and national/...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04706-1
更新日期：2021-02-01 00:00:00
abstract：:Diagnostic accuracy of anti-DNase I antibodies measurement in a differentiation between SLE and other autoimmune rheumatic diseases was evaluated. The share of anti-DNase I and actin in the DNase I activity decrease in SLE was established. Serum samples were obtained from 54 patients with verified SLE, 52 control pati...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3437-z
更新日期：2016-04-01 00:00:00
abstract：:Chondrocyte structure and function under the influence of two gold-containing therapeutic agents, aurothioglucose and triethylphosphine gold, were studied in a monolayer culture system for cultivating lapine articular chondrocytes. The functional parameters investigated were chondrocyte proliferation and the incorpora...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541144
更新日期：1983-01-01 00:00:00
abstract：:Bisphosphonates such as alendronate, risedronate and zoledronate have revolutionised the treatment for osteoporosis and Paget's disease. These drugs reduce fracture risk and probably mortality in patients with osteoporosis. However, they have a long in vivo half-life following cessation and may be associated with dela...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-013-2771-7
更新日期：2013-09-01 00:00:00
abstract：:Primary Sjögren syndrome (pS) is associated with autoantibodies such as rheumatoid factor (RF) and anti-nuclear antibodies such as anti-Ro (SS-A) and/or La (SS-B). Recent developments within autoimmune diagnostics allow quantitation of RF subclasses and anti-Ro epitopes. Will this refinement by autoimmune diagnostics ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4090-5
更新日期：2018-08-01 00:00:00
abstract：:In this cross-sectional study a comparison was made of rheumatoid factor (RF) isotypes in 203 RF positive patients with arthritis. Of these, 129 had rheumatoid arthritis (RA) and 74 a milder disease that would formerly have been classified as probable RA. The majority (74%) of the RA patients had elevations of two or ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00290265
更新日期：1992-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes joint pain, inflammation, and loss of function. Disease pathogenesis involves activation and proliferation of autoreactive pro-inflammatory effector T cells. While the details of RA onset and progression remain controversial, dendritic cell (DC) nu...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3671-z
更新日期：2017-07-01 00:00:00
abstract：:Sixty-six hospitalized patients with systemic lupus erythematosus (SLE) were enrolled into this study. The test for anti-mitochondrial antibodies (AMAs) was performed and biochemical parameters were determined. AMAs were detected in 15 of the 66 patients with SLE. Meanwhile, we compared enzymatic levels in AMA-positiv...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0034-y
更新日期：2006-06-01 00:00:00
abstract：:Rickettsia rickettsii, a tick borne disease, is the pathogen responsible for inducing Rocky Mountain Spotted Fever (RMSF), an illness that can progress to fulminant multiorgan failure and death. We present a case where R. rickettsii, acquired on a camping trip, precipitated a flare of peripheral arthritis and episcler...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-019-04330-8
更新日期：2019-09-01 00:00:00
abstract：:A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspir...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1113-2
更新日期：2010-11-01 00:00:00
abstract：:Arthrocutaneous disorders including Reiter's syndrome, psoriasiform rashes, and other forms of chronic arthritis and enthesopathy, such as psoriatic arthritis, occur with an increased prevalence in the setting of HIV infection. Herein we describe the spectrum and prevalence of musculoskeletal and allied skin disorders...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/BF00271870
更新日期：1989-01-01 00:00:00
abstract：:P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0307-8
更新日期：2007-07-01 00:00:00
abstract：:Wegener granulomatosis (WG) is a necrotizing granulomatous vasculitis that predominantly affects airways and kidneys. But central nervous system involvement (7-11%) is an uncommon. Massive ICH may occur in the course of WG, and this serious condition is related with high risk of mortality. Therefore, the new treatment...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1954-3
更新日期：2012-06-01 00:00:00
abstract：:Biological treatments aiming to neutralize TNF-alpha (tumour necrosis factor alpha) (infliximab, adalimumab and etanercept) are increasingly used to treat rheumatoid arthritis (RA). Although increased frequency has not been observed in randomized clinical trials with TNF-alpha antagonist agents, postmarketing surveill...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0165-9
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:Examine the association between physical activity and sedentary time with high sensitivity C-Reactive protein levels in adults with arthritis and fibromyalgia. We also investigated the dose of physical activity that was associated with lower clinical levels of high sensitivity C-Reactive protein (< 3 mg/L). MA...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04571-y
更新日期：2020-09-01 00:00:00
abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1907-x
更新日期：2012-07-01 00:00:00
abstract：:Metatarsalgia defined as pain at the plantar aspect of the forefoot. Intermetatarsal bursitis is considered one potential soft-tissue cause of metatarsalgia that is presumably under-estimated, under-investigated, and, consequently, often misdiagnosed. To assess the role of MRI in the elucidation of the cause of metata...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04381-x
更新日期：2019-12-01 00:00:00
abstract：:The aim of this study was to investigate (a) the mortality in a clinical cohort of patients with established rheumatoid arthritis in comparison with the general Dutch population over 15 years, (b) the trend in the mortality ratio during the study period, and (c) causes of death and compare these with the general popul...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3638-5
更新日期：2017-04-01 00:00:00
abstract：:HLA-DR antigens were determined in 111 patients with classic or definite rheumatoid arthritis. HLA-DR4 was significantly (P corr. less than 10(-6] increased in patients with rheumatoid arthritis (54%) compared with controls (23.2%). HLA-DR 5 was decreased in rheumatoid arthritis (12.6% vs 26.4% of controls); however, ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541190
更新日期：1983-01-01 00:00:00
