Abstract:
:Rickettsia rickettsii, a tick borne disease, is the pathogen responsible for inducing Rocky Mountain Spotted Fever (RMSF), an illness that can progress to fulminant multiorgan failure and death. We present a case where R. rickettsii, acquired on a camping trip, precipitated a flare of peripheral arthritis and episcleritis in an HLA-B27 positive patient. Although Yersinia, Salmonella, Mycobacteria, Chlamydia, Shigella, Campylobacter, and Brucella have been previously associated with HLA-B27 spondyloarthritis, this unusual case demonstrates that obligate intracellular rickettsial organisms, and specifically, R. rickettsii, can also induce flares of HLA-B27 spondyloarthritis. Rickettsial infections in general can rapidly become fatal in both healthy and immunosuppressed patients, and thus, prompt diagnosis and therapy are required.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Redford AH,Trost JR,Sibbitt WL Jr,Fangtham M,Emil NS,Singh S,Bankhurst ADdoi
10.1007/s00296-019-04330-8subject
Has Abstractpub_date
2019-09-01 00:00:00pages
1643-1650issue
9eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-019-04330-8journal_volume
39pub_type
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