Abstract：
:The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent examination of seven joints by 2D and 3D US for synovitis and tenosynovitis in B and PD modes and erosions in B mode. A global score for synovitis and global counts for synovitis, tenosynovitis and erosions were also calculated for every patient. Agreement between 2D and 3D US was analysed for counts and scores at the patient level with the intraclass correlation coefficient (ICC) and for counts at the joint level with Cohen's kappa coefficient. B-mode synovitis was detected at a median of five joints in each patient, frequently in wrists and hand joints but less frequently in foot joints. PD-mode synovitis, tenosynovitis and erosions were detected less frequently. All ICCs for agreement between 2D and 3D US findings were significant. All kappa coefficients were significant for B- and PD-mode synovitis and for erosions (except PIP3), while those for tenosynovitis were only significant for MCP2 (B and PD modes) and PIP2 (B mode). Although the 3D US volumes were acquired by inexperienced operators, agreement between 2D and 3D US was acceptable in detecting and scoring synovitis. A higher level of agreement was attained for patient-level global scores and counts than for individual joints.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Acebes C,McKay N,Ciechomska A,Alcorn N,Harvie JP,Robson B,Groenendijk N,McDonald M,Wilson A,Garrido Jdoi
10.1007/s00296-016-3606-0subject
Has Abstractpub_date
2017-02-01 00:00:00pages
197-205issue
2eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-016-3606-0journal_volume
37pub_type
杂志文章abstract：:The aim of this study was to evaluate whether cyclosporin A (CsA) influences the radiological disease progression in early rheumatoid arthritis (RA) patients in comparison with other disease-modifying drugs (DMARDs). A total of 103 early RA patients, without prior use of DMARDs, were randomized to receive CsA (3 mg/kg...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002960050113
更新日期：2000-01-01 00:00:00
abstract：:We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2137-y
更新日期：2012-10-01 00:00:00
abstract：:This retrospective medical chart review aimed to provide a current, real-world overview of biologic usage in patients with rheumatoid arthritis (RA) in Germany, Spain, and the UK, and estimate clinical and healthcare utilization outcomes associated with early versus late treatment. Adults (≥18 years) with a confirmed ...
journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00296-015-3312-3
更新日期：2015-11-01 00:00:00
abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1907-x
更新日期：2012-07-01 00:00:00
abstract：:We present the case of a patient with long-standing rheumatoid arthritis and an acute onset of total dysfunction of the posterior tibial tendon. On MRI, a rupture of the tendon was apparent. Intraoperatively, however, massive tenosynovitis with stricture of the tendon was identified as the cause of posterior tibial te...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0183-1
更新日期：2002-05-01 00:00:00
abstract：:We examined the agreement between self-reported osteoporosis and bone mineral density (BMD) results through dual-energy x-ray absorptiometry (DXA) using data from a national representative sample taken from the US communities. Six-year data from the continuous National Health and Nutrition Examination Survey 2005-2006...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3573-5
更新日期：2016-12-01 00:00:00
abstract：:The group of autoimmune cutaneous connective tissue diseases (CCTD) includes systemic sclerosis, dermatomyositis (DM), lupus erythematosus (LE), and subtypes. Most CCTD patients can be assigned to one of these phenotypes or mixed forms, and transitions among the subsets exist. We present the case of a 26-year-old woma...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0354-8
更新日期：2004-03-01 00:00:00
abstract：:The case of a 29-year-old white female with a 7-year history of typical scleroderma is presented who developed excessive fibrosis of the supraclavicular lymph nodes. After 3 years of disease, firm right supraclavicular lymphadenopathy appeared, accompanied by a high fever. Biopsy revealed non-caseating granulomas and ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00301013
更新日期：1993-01-01 00:00:00
abstract：:Anti-TNF drugs may increase lymphoma risk in autoimmune rheumatic diseases, such as rheumatoid arthritis, but there have been no reports stating increased risk of lymphoma in ankylosing spondylitis (AS). Before 2 years, we had presented a case with AS developing Hodgkin's lymphoma following 6 months of etanercept trea...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1265-0
更新日期：2011-12-01 00:00:00
abstract：:Fluoride excess primarily effects dental and skeletal tissues. leading to a condition known as endemic fluorosis. The radiological and clinical features of endemic fluorosis vary in different parts of the world. The aim of this study was to investigate the clinical and radiological features of endemic fluorosis in Tur...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960100132
更新日期：2001-09-01 00:00:00
abstract：KEY MESSAGES:No difference between both hands was observed for clinical and radiographical presentations in EHOA patients. A bilateral and symmetrical relationship was found between hand joints. HIGHLIGHTS:EHOA have symmetrical distribution and specific association in structural lesions. This study aims to analyse the...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04784-1
更新日期：2021-01-27 00:00:00
abstract：:Some infectious, rheumatic, allergic diseases, and malignancies have been associated with leucocytoclastic vasculitis (LCV). LCV and cancer occur most frequently in patients with hematological malignancies such as lymphomas and leukemias. There have been a few prior cases reported of LCV associated with renal cell car...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1063-8
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:Neprilysin (neutral endopeptidase, 3:4:24:11, CD10) (NEP) is a Zn metallopeptidase linked to controlling inflammation through the degradation of neuropeptides involved in neurogenic inflammation of chronic rheumatic diseases. The aim of our study was to evaluate circulating activity and cellular expression of...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0447-z
更新日期：2005-06-01 00:00:00
abstract：AIM:The aim of this study was to assess the efficacy of long-term azathioprine and steroids for treatment of severe nephritis in children with Henoch-Schönlein purpura (HSP). METHODS:Analysis of case records of children with HSP followed up for a mean duration of 4.7 years (range 6 months-6.5 years) was performed. All...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0208-9
更新日期：2002-08-01 00:00:00
abstract：:Behçet's syndrome (BS) is a chronic (auto)-inflammatory disorder characterized by different clusters of symptoms, including mucocutaneous and ocular involvements. Interleukin-1 inhibitors anakinra (ANA), canakinumab (CAN), and gevokizumab (GEV) represent a promising therapeutic alternative in BS. To date, evidence on ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04259-y
更新日期：2019-06-01 00:00:00
abstract：:The risk of herpes zoster among patients with juvenile idiopathic arthritis (JIA) exposed to biologics has not been evaluated. We determined incidence rates of herpes zoster among children with JIA in correlation with medication at time of occurrence and total drug exposure. The German biologics register database was ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3197-6
更新日期：2015-03-01 00:00:00
abstract：:Systemic sclerosis is a connective tissue disease, which may lead to elevated pulmonary arterial pressure due to pulmonary arterial hypertension and/or left ventricular diastolic dysfunction. Uric acid (UA) has been shown to be elevated in patients with pulmonary hypertension (PH) and heart failure. We aimed to invest...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1557-4
更新日期：2011-02-01 00:00:00
abstract：:We have recently reported on two cases of scleroderma patients with ANCA-associated vasculitis for the first time in Korea. In order to explore the nature of this disease combination, we pooled together all the previously known cases and statistically analyzed them. Out of the 50 selected cases, survival analysis was ...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-005-0011-5
更新日期：2006-03-01 00:00:00
abstract：:Immunofluorescence on polymorphonuclear cells (PMN) of patients with Felty syndrome (FS) revealed increased amounts of IgG, IgA, and IgM bound to the PMN surface compared with PMN of patients with rheumatoid arthritis alone. A positive correlation was found between the score for surface-bound immunoglobulins on FS-PMN...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541352
更新日期：1985-01-01 00:00:00
abstract：:The objective of the study was to study the clinical utility of the Ankylosing Spondylitis Disease Activity Score (ASDAS) for the assessment of disease activity in ankylosing spondylitis (AS) patients, compared to the Bath Ankylosing Spondylitis Activity Index (BASDAI). This was a prospective longitudinal observationa...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3814-2
更新日期：2017-11-01 00:00:00
abstract：:Although arthroscopic surgery (AS) for knee osteoarthritis has been widely employed, scientific evidence is lacking. The purpose of this study was to investigate temporal changes in synovial fluid levels of biochemical markers associated with cartilage metabolism following AS. Twenty-five knees of 24 patients with med...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2374-8
更新日期：2013-01-01 00:00:00
abstract：:Addison's disease is an autoimmune process. However, Addison's disease associated with connective tissue diseases (CTD) is only occasionally reported. Here, we report six cases of Addison's disease secondary to a variety of CTD, which include systemic lupus erythematosus, Takayasu arteritis, systemic sclerosis, ankylo...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0749-7
更新日期：2009-04-01 00:00:00
abstract：:Fatigue has a large impact on quality of life and is still unmanageable for many patients. Study aims were describe (1) the prevalence and pattern of fatigue over time in patients with early rheumatoid arthritis under a treat-to-target strategy and (2) identify predictive factors for worsening and recovering of fatigu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4102-5
更新日期：2018-09-01 00:00:00
abstract：:The objectives of this study are to describe appropriateness and drug treatment of comorbidities in fibromyalgia (FM). Cross-sectional study of a group of patients. Number of drugs, indication, duration and appropriateness of prescriptions were evaluated. Patients were classified as: group 1, (FM/FM) previous FM diagn...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3568-2
更新日期：2016-12-01 00:00:00
abstract：:To translate and culturally adapt the Mayo Elbow Performance Score (MEPS), a widely used instrument for evaluating disability associated with elbow injuries, into Turkish (MEPS-T) and to determine psychometric properties of the translated version. The MEPS was translated into Turkish using published methodological gui...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3201-1
更新日期：2015-06-01 00:00:00
abstract：:Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1547-6
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:Early arthritis clinics (EACs) have been well established since 1980s. Most of the data for their effectiveness comes from rheumatoid arthritis (RA) management and is largely limited to process outcomes. There is little evidence that such clinics improve clinical outcomes particularly for psoriatic arthrit...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04253-4
更新日期：2019-04-01 00:00:00
abstract：:To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cytotoxicity in the presence of phorbol dibutyrate. This chondrocyte damage was abolished by the addition of cat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00274933
更新日期：1992-01-01 00:00:00
abstract：:A critical analysis has been performed of reports published on the incidence of gastro-intestinal (GI) side-effects found in arthritic patients being treated with non-steroid anti-inflammatory (NSAI) drugs. The results show the following: 1. The incidence of GI ulceration (as revealed by gastroscopy) and haemorrhage i...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541263
更新日期：1982-01-01 00:00:00
abstract：:We report a case of sudden onset of late infection after TKA inflamed by anti-TNFalpha therapy, Infliximab, in a 54-year-old woman with RA. Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA. One week after the third administration of Infl...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0948-x
更新日期：2010-01-01 00:00:00
