当前位置： SCI文献检索 > RHEUMATOLOGY INTERNATIONAL期刊下所有文献 > Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.

Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.

Abstract：

:The risk of herpes zoster among patients with juvenile idiopathic arthritis (JIA) exposed to biologics has not been evaluated. We determined incidence rates of herpes zoster among children with JIA in correlation with medication at time of occurrence and total drug exposure. The German biologics register database was used to identify patients with herpes zoster. Crude infection rates and incidence ratios (IRR) were compared to published rates. Demographics and overall exposure and particular exposure time to corticosteroids, immunosuppressive drugs and biologics were analyzed. The JIA cohort included 3,042 patients with 5,557.9 person-years of follow-up; 1,628 have used corticosteroids, 2,930 methotrexate and 1,685 etanercept. In total, 17 herpes zoster events have been documented [6/1,000 patients (3.5-9.0); 3.1/1,000 patient-years (1.9-4.9)]. Thus, the incidence rate in JIA patients was higher than expected [IRR 2.9 (1.8-4.5), p < 0.001]. In all patients, the event resolved completely. There were two complications, one patient developed intercostal neuralgia, and one had a recurrent herpes zoster. Compared to the healthy population, a significant higher IRR is observed in JIA patients who received a monotherapy with etanercept or in combination with steroids and methotrexate, but not in JIA patients exposed to methotrexate without biologics. In comparison with our control group of patients treated with methotrexate, the IRR was higher for exposure to etanercept monotherapy and combination of etanercept and corticosteroids irrespective of methotrexate use. A generally higher incidence rate in JIA patients treated with etanercept was observed. No serious or refractory manifestations occurred.

journal_name

Rheumatol Int

journal_title

Rheumatology international

authors

Nimmrich S,Horneff G

doi

10.1007/s00296-014-3197-6

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

465-70

issue

3

eissn

0172-8172

issn

1437-160X

journal_volume

35

pub_type

杂志文章

相关文献

RHEUMATOLOGY INTERNATIONAL文献大全
  • Effect of exercise on the plasma BDNF levels in elderly women with knee osteoarthritis.

    abstract：:Knee osteoarthritis is a common disease in the elderly population worldwide. The alleviation of the symptoms associated with this disease can be achieved with physical exercise that induces a cascade of molecular and cellular processes. Of the neurotrophins, brain-derived neurotrophic factor (BDNF) appears to be the m...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-013-2786-0

    authors： Gomes WF,Lacerda AC,Mendonça VA,Arrieiro AN,Fonseca SF,Amorim MR,Teixeira AL,Teixeira MM,Miranda AS,Coimbra CC,Brito-Melo GE

    更新日期：2014-06-01 00:00:00

  • Atypical Kawasaki disease with remarkable paucity of signs and symptoms.

    abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-0899-2

    authors： Thapa R,Chakrabartty S

    更新日期：2009-07-01 00:00:00

  • Hyperleptinemia independent of body adiposity in women with fibromyalgia.

    abstract：:The prevalence of overweight and obesity in patients with fibromyalgia is high, which makes these patients more likely to trigger metabolic changes. It is also uncertain whether the clinical manifestations of fibromyalgia alter the metabolism in these patients. This study investigates the influence of adiposity indica...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-014-2988-0

    authors： Homann D,Carvalho HM,Stefanello JM,Góes SM,Lopes AL,de Oliveira AR,Leite N

    更新日期：2014-11-01 00:00:00

  • Meta-analysis of three double-blind comparative trials with sustained-release etodolac in the treatment of osteoarthritis of the knee.

    abstract：:A meta-analysis was done with the final data from three trials that provided the first results relating to efficacy and safety of the new sustained-release (SR) formulation of etodolac versus established nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis (OA) of the knee. The studies were...

    journal_title：Rheumatology international

    pub_type： 杂志文章,meta分析

    doi：10.1007/BF00290280

    authors： Porzio F

    更新日期：1993-01-01 00:00:00

  • Higher LPS-stimulated TNF-alpha mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308G/A polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes.

    abstract：:To investigate the effects of TNF-alpha -308, -238 promoter polymorphisms on TNF-alpha transcription in B27 positive Chinese patients with ankylosing spondylitis (AS). The possible relationship between polymorphisms, MHC antigens, and quantitative TNF-alpha mRNA expression were evaluated. Single nucleotide polymorphis...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-008-0671-z

    authors： Lu MC,Yang KL,Tung CH,Huang KY,Yu HC,Liu SQ,Lai NS

    更新日期：2008-12-01 00:00:00

  • Catalase and PPARgamma2 genotype and risk of rheumatoid arthritis in Koreans.

    abstract：:Catalase (CAT) and peroxisome proliferator activated receptor-gamma2 (PPARgamma2) are important regulators of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis (RA). We investigated the association between CAT and PPARgamma2 genotypes and risk and severity of RA using 474...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-005-0013-3

    authors： El-Sohemy A,Cornelis MC,Park YW,Bae SC

    更新日期：2006-03-01 00:00:00

  • Relapsing polychondritis with aortic arch aneurysm and aortic arch syndrome.

    abstract：:A case of relapsing polychondritis with aortic arch aneurysm and aortic arch syndrome is described. The pattern of vascular involvement supports the inclusion of relapsing polychondritis within the spectrum of systemic vasculitides. ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00541214

    authors： Giordano M,Valentini G,Sodano A

    更新日期：1984-01-01 00:00:00

  • Cross-cultural adaptation, validation, and responsiveness of the Korean version of the AUSCAN Osteoarthritis Index.

    abstract：:The Australian/Canadian Osteoarthritis Hand Index (AUSCAN) is a patient self-reported 15-item questionnaire measuring the severity of hand osteoarthritis symptoms in the respect of pain, stiffness, and function. In this study, we developed a Korean version of the AUSCAN Index (K-AUSCAN) and confirmed its reliability, ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-011-2227-x

    authors： Moon KW,Lee SS,Kim JH,Song R,Lee EY,Song YW,Bellamy N,Lee EB

    更新日期：2012-11-01 00:00:00

  • Current concepts in the pathophysiology of fibromyalgia: the potential role of oxidative stress and nitric oxide.

    abstract：:Fibromyalgia (FM) is a common chronic pain syndrome with an unknown etiology. Recent years added new information to our understanding of FM pathophysiology. Researches on genetics, biogenic amines, neurotransmitters, hypothalamic-pituitary-adrenal axis hormones, oxidative stress, and mechanisms of pain modulation, cen...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-005-0078-z

    authors： Ozgocmen S,Ozyurt H,Sogut S,Akyol O

    更新日期：2006-05-01 00:00:00

  • Methotrexate for rheumatoid arthritis patients who are on hemodialysis.

    abstract：:Methotrexate (MTX) can be toxic to patients suffering from end stage renal disease (ESRD) on hemodialysis even at low doses. This increase in toxicity is more notable in terms of bone marrow suppression in the form of pancytopenia. Many methods of elimination including dialysis itself have been proven ineffective, and...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-011-2041-5

    authors： Al-Hasani H,Roussou E

    更新日期：2011-12-01 00:00:00

  • Health-related quality of life (Nottingham Health Profile) in knee osteoarthritis: correlation with clinical variables and self-reported disability.

    abstract：:The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 fema...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-1195-x

    authors： Yildiz N,Topuz O,Gungen GO,Deniz S,Alkan H,Ardic F

    更新日期：2010-11-01 00:00:00

  • Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis.

    abstract：:The synovial fluids (SF) of patients with rheumatoid arthritis (RA) were investigated for their effects on thymocytes of C3H/HeJ mice. Of the 20 SF tested, 17 (85%) showed an augmentation of the phytohaemagglutinin (PHA) induced thymocyte stimulation. Out of 16 SF of patients with osteoarthrosis, such an activity was ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00541245

    authors： Fontana A,Hengartner H,Weber E,Fehr K,Grob PJ,Cohen G

    更新日期：1982-01-01 00:00:00

  • Hydroxychloroquine ototoxicity in a patient with rheumatoid arthritis.

    abstract：:We report a case of reversible sensorineural hearing loss due to hydroxychloroquine (HQ) treatment. The patient was a 34-year-old woman with 1 year of rheumatoid arthritis (RA). She developed reversible hearing loss after 5 months of HQ treatment. Sensorineural deafness has previously been reported with chloroquine tr...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s002960000054

    authors： Seçkin U,Ozoran K,Ikinciogullari A,Borman P,Bostan EE

    更新日期：2000-01-01 00:00:00

  • Clinical presentation, treatment and outcome of Takayasu's arteritis in southern Chinese: a multicenter retrospective study.

    abstract：:To study the clinical presentation, treatment and outcome of southern Chinese patients with Takayasu's arteritis (TA). This is a retrospective chart review study of 78 patients managed in 14 public hospitals in Hong Kong between the years 2000 and 2010. Patients were identified from the hospital registry using the ICD...

    journal_title：Rheumatology international

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00296-018-4150-x

    authors： Wong SPY,Mok CC,Lau CS,Yip ML,Tam LS,Ying KY,Ng WL,Ng KH,Leung MH,Lee TY,To CH,Lee KL,Wan MC,Yu KL,Wong PCH,Sung CK,Lee KF,Kun EWL,Hong Kong Takayasu’s arteritis study group.

    更新日期：2018-12-01 00:00:00

  • Etodolac: efficacy in osteoarthritis and effects on chondrocyte function.

    abstract：:Some nonsteroidal anti-inflammatory drugs (NSAIDs) used in the treatment of osteoarthritis (OA) may damage articular cartilage. This damage may be caused by suppression of proteoglycan synthesis or by altered collagen synthesis in the presence of prostaglandin E2 (PGE2) induced by interleukin-1 (IL-1). The clinical an...

    journal_title：Rheumatology international

    pub_type： 临床试验,杂志文章,评审

    doi：10.1007/BF02274749

    authors： Bacon PA

    更新日期：1990-01-01 00:00:00

  • The expression of RANKL and OPG in the various grades of osteoarthritic cartilage.

    abstract：:The objective of the study was to determine whether cartilage expression of the bone regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and osteoprotegerin (OPG) varies between the different grades of osteoarthritis (OA). Cartilage samples were obtained from 30 patients undergoing total hip/kn...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-010-1733-6

    authors： Upton AR,Holding CA,Dharmapatni AA,Haynes DR

    更新日期：2012-02-01 00:00:00

  • High frequency of inflammatory back pain and other features of spondyloarthritis in patients with rheumatoid arthritis.

    abstract：:The aim of this study was to investigate the frequency of patients with rheumatoid arthritis (RA) who have inflammatory back pain (IBP) and meet the existing classification criteria for ankylosing spondylitis (AS) and spondyloarthritis (SpA). We included 167 patients fulfilling the ACR 1987 revised criteria for RA. Af...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-012-2553-7

    authors： Can G,Solmaz D,Binicier O,Akar S,Birlik M,Soysal O,Akkoc N,Manisali M,Onen F

    更新日期：2013-05-01 00:00:00

  • Klippel-Feil syndrome misdiagnosed as spondyloarthropathy: case-based review.

    abstract：:Spondyloarthropathy refers to any joint disease of the vertebral column, but the term is mainly used for a specific group of disorders called seronegative spondyloarthropathies (SpAs). The axial skeletal involvement, peripheral and extra-articular manifestations and an association with the major histocompatibility com...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-019-04346-0

    authors： Čota S,Žagar I,Delimar V,Pap M,Perić D,Perić P

    更新日期：2019-09-01 00:00:00

  • Matrix metalloproteinase genes on chromosome 11q22 and risk of carpal tunnel syndrome.

    abstract：:Involvement of tendons and/or connective tissue structures in the aetiology of idiopathic carpal tunnel syndrome (CTS) has been proposed. DNA sequence variants within genes encoding structural components of the collagen fibril, the basic structural unit of connective tissue, have been shown to associate with modulatin...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-015-3385-z

    authors： Burger MC,De Wet H,Collins M

    更新日期：2016-03-01 00:00:00

  • Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate.

    abstract：:The aim of this study was to identify the possible determinants of impaired health-related quality of life (HRQOL) in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). Fifty-eight consecutive patients of JIA aged from 8 to 18 years underwent assessment of socio-economic and demographic charac...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-014-2950-1

    authors： Abdul-Sattar AB,Elewa EA,El-Shahawy Eel-D,Waly EH

    更新日期：2014-08-01 00:00:00

  • Fibromyalgia subgroups: profiling distinct subgroups using the Fibromyalgia Impact Questionnaire. A preliminary study.

    abstract：:The main goal of this project was to identify the presence of fibromyalgia (FM) subgroups using a simple and frequently used clinical tool, the Fibromyalgia Impact Questionnaire (FIQ). A total of 61 women diagnosed with FM participated in this study. FM subgroups were created by applying a hierarchical cluster analysi...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-008-0722-5

    authors： de Souza JB,Goffaux P,Julien N,Potvin S,Charest J,Marchand S

    更新日期：2009-03-01 00:00:00

  • Determination of inflammation of reflex sympathetic dystrophy at early stages with Tc-99m HIG scintigraphy: preliminary results.

    abstract：:The pathogenesis of reflex sympathetic dystrophy (RSD) is not completely understood. However, an excessive regional inflammation, sensitization of primary somatosensory afferents, and sensitization of spinal neurons are considered to have a role in the pathogenesis of RSD. The underlying pathophysiology relating the c...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-005-0009-z

    authors： Okudan B,Celik C

    更新日期：2006-03-01 00:00:00

  • Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis.

    abstract：:This study investigated the prevalence of antibody against annexin II (A2) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). It also explored the role of this antibody in thrombosis. Purified recombinant A2 was used in ELISA to measure the levels of IgG anti-A2 antibody in 101 AP...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-010-1379-4

    authors： Ao W,Zheng H,Chen XW,Shen Y,Yang CD

    更新日期：2011-07-01 00:00:00

  • Paleopathological interpretations of hypermobility syndrome in the art from ancient America.

    abstract：:Paleopathological representations of hypermobility syndrome were assumed in pre-Columbian artifacts from different ancient civilizations from America. Anthropomorphic sculptures from several museums and galleries visited on site or thru Internet show the human figure in contorted positions. These positions are only po...

    journal_title：Rheumatology international

    pub_type： 历史文章,杂志文章

    doi：10.1007/s00296-011-2007-7

    authors： Checa A

    更新日期：2012-10-01 00:00:00

  • Cost per response for abatacept versus adalimumab in rheumatoid arthritis by ACPA subgroups in Germany, Italy, Spain, US and Canada.

    abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disorder leading to disability and reduced quality of life. Effective treatment with biologic DMARDs poses a significant economic burden. The Abatacept versus Adalimumab Comparison in Biologic-Naïve RA Subjects with Background Methotrexate (AMPLE) trial was a head-to...

    journal_title：Rheumatology international

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00296-017-3739-9

    authors： Weijers L,Baerwald C,Mennini FS,Rodríguez-Heredia JM,Bergman MJ,Choquette D,Herrmann KH,Attinà G,Nappi C,Merino SJ,Patel C,Mtibaa M,Foo J

    更新日期：2017-07-01 00:00:00

  • High-frequency sensorineural hearing loss in patients with ankylosing spondylitis: is it an extrarticuler feature of disease?

    abstract：OBJECTIVE:The aim of this study was to investigate the ear involvement, especially at extended higher frequencies than those previously studied, in patients with ankylosing spondylitis (AS). PATIENTS AND METHODS:We prospectively evaluated 45 consecutive patients with AS. All patients underwent a complete physical exam...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-007-0458-7

    authors： Adam M,Erkan AN,Arslan D,Leblebici B,Ozlüoğlu L,Nafiz Akman M

    更新日期：2008-03-01 00:00:00

  • Autophagy is a key feature in the pathogenesis of systemic sclerosis.

    abstract：:Autophagosomes are formed during autophagy, which is activated by hypoxia and starvation. Autophagy is important for mast cell degranulation. We hypothesized that autophagy is a key feature in the pathogenesis of systemic sclerosis (SSc). We examined SSc clinical features and mast cell density across the presence and ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-013-2827-8

    authors： Frech T,De Domenico I,Murtaugh MA,Revelo MP,Li DY,Sawitzke AD,Drakos S

    更新日期：2014-03-01 00:00:00

  • Excessive fibrosis of supraclavicular lymph-node granulomas in a patient with progressive systemic sclerosis.

    abstract：:The case of a 29-year-old white female with a 7-year history of typical scleroderma is presented who developed excessive fibrosis of the supraclavicular lymph nodes. After 3 years of disease, firm right supraclavicular lymphadenopathy appeared, accompanied by a high fever. Biopsy revealed non-caseating granulomas and ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00301013

    authors： Andonopoulos AP,Tzanakakis G

    更新日期：1993-01-01 00:00:00

  • Evaluation of classification criteria for juvenile-onset spondyloarthropathies.

    abstract：OBJECTIVE:The aim of this study was to investigate the adequacy of the following criteria for the classification of juvenile-onset spondyloarthropathies (JSpA): European Spondyloarthropathy Study Group criteria (ESSGCr) and Amor criteria (ACr) (proposed for adult SpA), Garmisch-Partenkirchen (G-PCr), seronegative enthe...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-004-0460-2

    authors： Kasapçopur O,Demirli N,Ozdoğan H,Apelyan M,Calişkan S,Sever L,Arisoy N

    更新日期：2005-08-01 00:00:00

  • The distinct expressions of interleukin-15 and interleukin-15 receptor α in Behçet's disease.

    abstract：:Interleukin-15 (IL-15) is a pleotrophic cytokine that is involved in the pathogenesis of diverse inflammatory rheumatic diseases. The aims of this study were to compare serum IL-15 levels and expression of its receptor (IL-15Rα) in Behçet's disease (BD) with those in other rheumatic diseases and to identify the relati...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-013-2705-4

    authors： Choe JY,Lee H,Kim SG,Kim MJ,Park SH,Kim SK

    更新日期：2013-08-01 00:00:00