Abstract:
:We have recently reported on two cases of scleroderma patients with ANCA-associated vasculitis for the first time in Korea. In order to explore the nature of this disease combination, we pooled together all the previously known cases and statistically analyzed them. Out of the 50 selected cases, survival analysis was done for comparison of the scleroderma disease period and the clinical factors associated with ANCA-associated vasculitis (AAV). Kaplan-Meier analysis revealed that patients having anti-topoisomerase antibody (anti-Scl-70) and, probably, PR-3 ANCA are at a higher risk for developing AAV than patients without both anti-topoisomerase antibody and anti-centromere antibody (ACA), and patients with MPO-ANCA. Multivariate Cox regression analysis revealed having anti-topoisomerase antibody as a risk factor for developing AAV [OR 3.1 (95% CI 1.11-8.55), P=0.031]. We suggest that having anti-topoisomerase antibodies may play a role among scleroderma patients in developing AAV.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Rho YH,Choi SJ,Lee YH,Ji JD,Song GGdoi
10.1007/s00296-005-0011-5subject
Has Abstractpub_date
2006-03-01 00:00:00pages
369-75issue
5eissn
0172-8172issn
1437-160Xjournal_volume
26pub_type
杂志文章,评审abstract::The aim of this study was to evaluate whether the serum concentration of interleukin-6 (IL-6) reflects disease activity in ankylosing spondylitis (AS). A group of 271 AS patients were enrolled in the study, 261 of whom completed the entire protocol (201 males, 60 females, median age of 53 years). Serum IL-6 was measur...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s002960050066
更新日期:1998-01-01 00:00:00
abstract::Patients with rheumatoid arthritis (RA) showed significantly (P < 0.01) increased numbers of granulocytes in their peripheral blood compared with normal donors and patients with osteoarthritis, and this finding correlated with interleukin-6 and C-reactive protein levels and active joint score. Then, 17 patients with R...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00290518
更新日期:1996-01-01 00:00:00
abstract::Systemic sclerosis is a connective tissue disease, which may lead to elevated pulmonary arterial pressure due to pulmonary arterial hypertension and/or left ventricular diastolic dysfunction. Uric acid (UA) has been shown to be elevated in patients with pulmonary hypertension (PH) and heart failure. We aimed to invest...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1557-4
更新日期:2011-02-01 00:00:00
abstract::Adult-onset Still's disease (AOSD) is known as a systemic inflammatory disease of unknown etiology and pathogenesis, characterized by fever, skin eruptions, systemic organ involvement, and arthralgias. AOSD is difficult to diagnose because of its heterogeneous clinical manifestations and prevalence (although more prev...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1991-y
更新日期:2012-08-01 00:00:00
abstract::TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is mainly adipocyte-derived hormone controlling appetite and energy expenditure. It acts through inhibition of neuropeptide Y secretion. It is possible that TNF-α-...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2182-6
更新日期:2012-11-01 00:00:00
abstract::The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1519-x
更新日期:2011-12-01 00:00:00
abstract::Fifty-five patients with systemic lupus erythematosus (SLE) were examined for antineutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence (IIF). Enzyme-linked immunosorbent assay (ELISA) for ANCA against myeloperoxidase (MPO), lactoferrin (LF), proteinase 3 (PR3), elastase (HLE), and bactericidal/perme...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960100108
更新日期:2001-07-01 00:00:00
abstract::Radiation synovectomy (RS) is one of many therapeutic options used for recurrent joint synovitis. Our aim was to analyze the effect of the surgical synovectomy combined with yttrium 90 ((90)Y) in the treatment for recurrent joint synovitis. A surgical combined RS procedure was used on 32 knees of 30 patients. They wer...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2540-z
更新日期:2013-05-01 00:00:00
abstract::In a study of synovial fluid from 110 patients with various forms of arthritis, platelets were identified in the synovial fluid of all the 50 rheumatoids, in 18 out of the 25 (72%) with osteoarthritis and in all 35 of those with other forms of inflammatory osteoarthrosis. Identification of platelets by light microscop...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00683878
更新日期:1984-01-01 00:00:00
abstract::Elderly often have Heberden nodes (HN) and Bouchard nodes (BN) that may affect finger dexterity. The aim of this cross-sectional study was to assess an effect of HN and BN on finger dexterity of the elderly. The nine-hole peg test was used for dexterity measurement in 200 elderly with HN and/or BN. Mean age was 68.6 +...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1196-9
更新日期:2010-02-01 00:00:00
abstract::The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2937-3
更新日期:2014-08-01 00:00:00
abstract::The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent exami...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3606-0
更新日期:2017-02-01 00:00:00
abstract::In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conv...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04584-7
更新日期:2020-06-01 00:00:00
abstract::Behçet's disease (BD) is a variable vessel vasculitis characterized by recurrent oral and genital aphthosis accompanied by skin, ocular, gastrointestinal, neurologic, and articular involvement. BD is not common in childhood and the disease characteristics considerably differ between adults and children. 18 diagnostic/...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-018-4208-9
更新日期:2019-01-01 00:00:00
abstract::The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with avai...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04762-7
更新日期:2021-01-02 00:00:00
abstract::We report a case of sudden onset of late infection after TKA inflamed by anti-TNFalpha therapy, Infliximab, in a 54-year-old woman with RA. Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA. One week after the third administration of Infl...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0948-x
更新日期:2010-01-01 00:00:00
abstract::The objective of this study was to analyze the clinical characteristics, associated disorders, and the most common sites of stress fractures in rheumatological patients. Over a 3-year period, 35 patients with 44 stress fractures were prospectively recruited from an outpatient rheumatological department (32 postmenopau...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0194-y
更新日期:2002-06-01 00:00:00
abstract::The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthrogenic. Bovine type II collagen ind...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274777
更新日期:1990-01-01 00:00:00
abstract::Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenic role. The presence of nailfold capillary abnormalities is useful in diagnosing SSc. Capillaroscopy, however, usually requires special equipment and may be time consuming. Dermatoscope has been presented as...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1532-0
更新日期:2011-12-01 00:00:00
abstract::Statistical analysis plays a critical role in data interpretation in all fields and particularly so for clinical data where important treatment decisions are made. We provide here an in-depth and illustrative analysis to examine patterns and radiographic scores in an early disease rheumatoid arthritis cohort over a 3-...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2879-9
更新日期:2014-02-01 00:00:00
abstract::Adult-onset Still's disease (AOSD) is a systemic inflammatory disease in which a variety of thrombotic events may occur. However, to our knowledge, portal vein thrombosis (PVT), a potential cause of gastrointestinal bleeding, has not been described in the English literature. A previously well 47-year-old man diagnosed...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-009-0894-7
更新日期:2009-10-01 00:00:00
abstract::This study was performed to evaluate the effects of the TNF-alpha inhibitor etanercept on oxidation stress markers representing DNA damage, lipid peroxidation, and protein glycosylation. Twenty-two rheumatoid arthritis (RA) patients underwent etanercept treatment. The levels of serum total, urinary total, and urinary ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0419-1
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The present study was performed to localize the articular deposition of monosodium urate (MSU) crystal in joints. We compare the detection efficiencies of dual-energy CT (DECT) and ultrasound scans. METHODS:Analyses by DECT and ultrasound were performed with 184 bilateral joints of the lower limbs of 54 cons...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-3994-4
更新日期:2018-05-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a multifactorial disease. A combination of genetic and environmental risk factors contributes to its etiology. Several genes have been reported to be associated with susceptibility to the development of RA. The MHC2TA and FCRL3 genes have been associated previously with RA in Swedish and J...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-015-3358-2
更新日期:2016-02-01 00:00:00
abstract::Dissemination of research studies is important for research ideas to be transformed from initial abstracts to full publications. Analyses of the scientific impact and publication record of the Canadian Rheumatology Association (CRA) Annual meeting have not been previously described. This study determines the publicati...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-017-3701-x
更新日期:2017-06-01 00:00:00
abstract::We report our experience and hypothesis on the diagnosis and treatment of patients with vasculitis who are simultaneously diagnosed with serum-positive cytomegalovirus (CMV) immunoglobulin (Ig)M antibodies and negative CMV DNA polymerase chain reaction (PCR). It remains unknown how to treat this kind of "phantom" CMV ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0522-5
更新日期:2005-10-01 00:00:00
abstract::To determine the forms and characteristics of rheumatic diseases whose initial presentation mimics septic arthritis. Retrospective study of 398 patients hospitalized between 1979 and 2005 for arthritis diagnosed and treated as septic. In 10 cases, initial presentation of a rheumatic disease was highly suggestive of se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2364-x
更新日期:2013-08-01 00:00:00
abstract::Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0502-9
更新日期:2005-05-01 00:00:00
abstract::The cost-effectiveness of treatments that have the potential to change the "natural history" of a chronic progressive disease has to be evaluated over the long term. Cost-effectiveness estimates have been based on the concept that, with treatment, patients will not progress to the next level(s) of disease severity or ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1502-6
更新日期:2011-11-01 00:00:00
abstract::We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two g...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04275-y
更新日期:2019-06-01 00:00:00